diff --git a/pkgs/development/python-modules/mypy-boto3/default.nix b/pkgs/development/python-modules/mypy-boto3/default.nix
index 0ced918e8cd9..65f50ef39116 100644
--- a/pkgs/development/python-modules/mypy-boto3/default.nix
+++ b/pkgs/development/python-modules/mypy-boto3/default.nix
@@ -1342,8 +1342,8 @@ in
       "sha256-EGelGYE1b7seBg7WHOnY1Vumlw8iMqBAMIuUpPmIUIA=";
 
   mypy-boto3-synthetics =
-    buildMypyBoto3Package "synthetics" "1.43.33"
-      "sha256-vfHbGu/CUJKHLc7G5FVwvedPdsQ6d0ft5vlU25khVdQ=";
+    buildMypyBoto3Package "synthetics" "1.43.45"
+      "sha256-WEz+PMPa1ojI7uyLyMq2s5P6u19uBI/8pra73oWsyKA=";
 
   mypy-boto3-textract =
     buildMypyBoto3Package "textract" "1.43.0"