diff --git a/pkgs/by-name/uv/uv/package.nix b/pkgs/by-name/uv/uv/package.nix
index ce3acab23aa7..c91c318c34a8 100644
--- a/pkgs/by-name/uv/uv/package.nix
+++ b/pkgs/by-name/uv/uv/package.nix
@@ -81,5 +81,10 @@ rustPlatform.buildRustPackage (finalAttrs: {
       prince213
     ];
     mainProgram = "uv";
+
+    # Builds on 32-bit platforms fails with "out of memory" since at least 0.8.6.
+    # We don't place this in `badPlatforms` because cross-compilation on 64-bit
+    # machine may work, e.g. `pkgsCross.gnu32.uv`.
+    broken = stdenv.buildPlatform.is32bit;
   };
 })