diff --git a/pkgs/development/python-modules/rustworkx/default.nix b/pkgs/development/python-modules/rustworkx/default.nix
new file mode 100644
index 000000000000..09f15fdc1c94
--- /dev/null
+++ b/pkgs/development/python-modules/rustworkx/default.nix
@@ -0,0 +1,47 @@
+{ fetchFromGitHub
+, buildPythonPackage
+, rustPlatform
+, setuptools-rust
+, numpy
+, fixtures
+, networkx
+, libiconv
+, stdenv
+, lib
+}:
+
+buildPythonPackage rec {
+  pname = "rustworkx";
+  version = "0.12.1";
+
+  src = fetchFromGitHub {
+    owner = "Qiskit";
+    repo = pname;
+    rev = version;
+    hash = "sha256-d/KCxhJdyzhTjwJZ+GsXJE4ww30iPaXcPngpCi4hBZw=";
+  };
+
+  cargoDeps = rustPlatform.fetchCargoTarball {
+    inherit src;
+    hash = "sha256-imhiPj763iumRQb+oeBOpICD1nCvzZx+3yQWu1QRRQQ=";
+  };
+
+  nativeBuildInputs = [ setuptools-rust ] ++ (with rustPlatform; [
+    cargoSetupHook
+    rust.cargo
+    rust.rustc
+  ]);
+
+  buildInputs = [ numpy ] ++ lib.optionals stdenv.isDarwin [ libiconv ];
+
+  checkInputs = [ fixtures networkx ];
+
+  pythonImportsCheck = [ "rustworkx" ];
+
+  meta = with lib; {
+    description = "A high performance Python graph library implemented in Rust.";
+    homepage = "https://github.com/Qiskit/rustworkx";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ raitobezarius ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 1fc4fe9ed5e5..b54543c3c4a7 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -12123,6 +12123,8 @@ self: super: with self; {
 
   tzlocal = callPackage ../development/python-modules/tzlocal { };
 
+  rustworkx = callPackage ../development/python-modules/rustworkx { };
+
   uamqp = callPackage ../development/python-modules/uamqp {
     openssl = pkgs.openssl_1_1;
     inherit (pkgs.darwin.apple_sdk.frameworks) CFNetwork CoreFoundation Security;