diff --git a/pkgs/applications/radio/gnuradio/3.9.nix b/pkgs/applications/radio/gnuradio/3.9.nix
index 606681b1d6c8..b6a8ebd2dd8e 100644
--- a/pkgs/applications/radio/gnuradio/3.9.nix
+++ b/pkgs/applications/radio/gnuradio/3.9.nix
@@ -154,6 +154,7 @@ let
       pythonRuntime = with python.pkgs; [
         scipy
         pyqtgraph
+        pyqt5
       ];
     };
     gr-analog = {
diff --git a/pkgs/applications/radio/gnuradio/default.nix b/pkgs/applications/radio/gnuradio/default.nix
index de851c24fa28..9d05e1151bd8 100644
--- a/pkgs/applications/radio/gnuradio/default.nix
+++ b/pkgs/applications/radio/gnuradio/default.nix
@@ -156,6 +156,7 @@ let
       pythonRuntime = with python.pkgs; [
         scipy
         pyqtgraph
+        pyqt5
       ];
     };
     gr-analog = {
diff --git a/pkgs/development/python-modules/binwalk/default.nix b/pkgs/development/python-modules/binwalk/default.nix
index 0f3d10d2b306..d3ebcbe91e37 100644
--- a/pkgs/development/python-modules/binwalk/default.nix
+++ b/pkgs/development/python-modules/binwalk/default.nix
@@ -19,6 +19,7 @@
   nose,
   pycrypto,
   pyqtgraph,
+  pyqt5,
   visualizationSupport ? false,
 }:
 
@@ -61,6 +62,7 @@ buildPythonPackage rec {
     ++ lib.optionals visualizationSupport [
       matplotlib
       pyqtgraph
+      pyqt5
     ]
     ++ lib.optionals (!stdenv.isDarwin) [
       cramfsprogs
diff --git a/pkgs/development/python-modules/enamlx/default.nix b/pkgs/development/python-modules/enamlx/default.nix
index 2cc2522c0d9d..4d181fab7032 100644
--- a/pkgs/development/python-modules/enamlx/default.nix
+++ b/pkgs/development/python-modules/enamlx/default.nix
@@ -4,6 +4,7 @@
   fetchFromGitHub,
   enaml,
   pyqtgraph,
+  pyqt5,
   pythonocc-core,
   typing-extensions,
 }:
@@ -24,6 +25,7 @@ buildPythonPackage rec {
     enaml
     # Until https://github.com/inkcut/inkcut/issues/105 perhaps
     pyqtgraph
+    pyqt5
     pythonocc-core
     typing-extensions
   ];
diff --git a/pkgs/development/python-modules/orange3/default.nix b/pkgs/development/python-modules/orange3/default.nix
index e59e2a5dfaad..a235fef5f044 100644
--- a/pkgs/development/python-modules/orange3/default.nix
+++ b/pkgs/development/python-modules/orange3/default.nix
@@ -29,6 +29,7 @@
   pytestCheckHook,
   pytest-qt,
   pyqtgraph,
+  pyqt5,
   pyqtwebengine,
   python,
   python-louvain,
@@ -113,6 +114,7 @@ let
       xlsxwriter
       httpx
       pyqtgraph
+      pyqt5
       orange-widget-base
       keyrings-alt
       pyyaml
diff --git a/pkgs/development/python-modules/pyqtgraph/default.nix b/pkgs/development/python-modules/pyqtgraph/default.nix
index 718b0be18477..6bfa11c30fcb 100644
--- a/pkgs/development/python-modules/pyqtgraph/default.nix
+++ b/pkgs/development/python-modules/pyqtgraph/default.nix
@@ -5,14 +5,13 @@
   fetchFromGitHub,
   scipy,
   numpy,
-  pyqt5,
+  pyqt6,
   pyopengl,
-  qt5,
+  qt6,
   pytestCheckHook,
   freefont_ttf,
   makeFontsConf,
   setuptools,
-  python,
 }:
 
 let
@@ -34,15 +33,20 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [
     numpy
-    pyqt5
     scipy
     pyopengl
   ];
+  buildInputs = [
+    # Not propagating it so that every consumer of this package will be able to
+    # use any of the upstream supported Qt Library, See:
+    # https://pyqtgraph.readthedocs.io/en/pyqtgraph-0.13.7/getting_started/how_to_use.html#pyqt-and-pyside
+    pyqt6
+  ];
 
   nativeCheckInputs = [ pytestCheckHook ];
 
   preCheck = ''
-    export QT_PLUGIN_PATH="${qt5.qtbase.bin}/${qt5.qtbase.qtPluginPrefix}"
+    export QT_PLUGIN_PATH="${lib.getBin qt6.qtbase}/${qt6.qtbase.qtPluginPrefix}"
     export QT_QPA_PLATFORM=offscreen
     export DYLD_FRAMEWORK_PATH=/System/Library/Frameworks
     export FONTCONFIG_FILE=${fontsConf}
@@ -65,13 +69,12 @@ buildPythonPackage rec {
       "test_rescaleData"
     ];
 
-  meta = with lib; {
+  meta = {
     description = "Scientific Graphics and GUI Library for Python";
     homepage = "https://www.pyqtgraph.org/";
     changelog = "https://github.com/pyqtgraph/pyqtgraph/blob/master/CHANGELOG";
-    license = licenses.mit;
-    broken = lib.versionAtLeast python.version "3.12";
-    platforms = platforms.unix;
-    maintainers = with maintainers; [ koral ];
+    license = lib.licenses.mit;
+    platforms = lib.platforms.unix;
+    maintainers = with lib.maintainers; [ koral doronbehar ];
   };
 }