diff --git a/nixos/modules/system/boot/stage-2-init.sh b/nixos/modules/system/boot/stage-2-init.sh
index fa2884d08708..e960f1bbcc39 100755
--- a/nixos/modules/system/boot/stage-2-init.sh
+++ b/nixos/modules/system/boot/stage-2-init.sh
@@ -61,25 +61,44 @@ else
 fi
 
 
-# Make /nix/store a read-only bind mount to enforce immutability of
-# the Nix store.  Note that we can't use "chown root:nixbld" here
+# Give /nix/store the defined mount options.
+# Typically, this should be:
+# - 'ro' to enforce immutability of the Nix store
+# - 'nosuid' to enforce no suid binaries make it into the store and get executed by accident.
+#   suid-binaries should only exist in /run/wrappers.
+#   If an attacker can make the nix builder produce suid binaries in the store, those should be useless.
+#   Another example is tampering with the store from an outside system.
+# - 'nodev' to enforce no device files in the store
+# Note that we can't use "chown root:nixbld" here
 # because users/groups might not exist yet.
+
 # Silence chown/chmod to fail gracefully on a readonly filesystem
 # like squashfs.
 chown -f 0:30000 /nix/store
 chmod -f 1775 /nix/store
-if [ -n "@readOnlyNixStore@" ]; then
-    # #375257: Ensure that we pick the "top" (i.e. last) mount so we don't get a false positive for a lower mount.
-    if ! [[ "$(findmnt --direction backward --first-only --noheadings --output OPTIONS /nix/store)" =~ (^|,)ro(,|$) ]]; then
-        if [ -z "$container" ]; then
-            mount --bind /nix/store /nix/store
-        else
-            mount --rbind /nix/store /nix/store
-        fi
-        mount -o remount,ro,bind /nix/store
-    fi
-fi
 
+missing_opts=() # stores the missing mount options that still need to be applied to the nix store
+current_opts="$(findmnt --direction backward --first-only --noheadings --output OPTIONS /nix/store)"
+for mount_opt in @nixStoreMountOpts@ ; do
+    # #375257: Ensure that we pick the "top" (i.e. last) mount so we don't get a false positive for a lower mount.
+    # matches '$opt', foo,$opt', '$opt,foo', 'foo,$opt,bar'
+    # crucially, it does not match 'foo$opt', otherwise e.g. 'errors=remount-ro' would yield false positives for 'ro'
+    if ! [[ "$current_opts" =~ (^|,)"$mount_opt"(,|$) ]]; then
+        missing_opts+=("$mount_opt")
+    fi
+done
+
+# only change the mount options if any need changing
+if [[ ${#missing_opts[@]} != 0 ]]; then
+    if [ -z "$container" ]; then
+        mount --bind /nix/store /nix/store
+    else
+        mount --rbind /nix/store /nix/store
+    fi
+
+    # apply the missing mount options
+    mount -o remount,"$(IFS=, ; echo "${missing_opts[*]}")",bind /nix/store
+fi
 
 if [ "${IN_NIXOS_SYSTEMD_STAGE1:-}" != true ]; then
     # Use /etc/resolv.conf supplied by systemd-nspawn, if applicable.
diff --git a/nixos/modules/system/boot/stage-2.nix b/nixos/modules/system/boot/stage-2.nix
index d72ea225fb24..af90496753d9 100644
--- a/nixos/modules/system/boot/stage-2.nix
+++ b/nixos/modules/system/boot/stage-2.nix
@@ -17,7 +17,8 @@ let
     replacements = {
       shell = "${pkgs.bash}/bin/bash";
       systemConfig = null; # replaced in ../activation/top-level.nix
-      inherit (config.boot) readOnlyNixStore systemdExecutable;
+      inherit (config.boot) systemdExecutable;
+      nixStoreMountOpts = lib.concatStringsSep " " (map lib.escapeShellArg config.boot.nixStoreMountOpts);
       inherit (config.system.nixos) distroName;
       inherit useHostResolvConf;
       inherit (config.system.build) earlyMountScript;
@@ -57,11 +58,28 @@ in
         description = ''
           If set, NixOS will enforce the immutability of the Nix store
           by making {file}`/nix/store` a read-only bind
-          mount.  Nix will automatically make the store writable when
+          mount. Nix will automatically make the store writable when
           needed.
         '';
       };
 
+      nixStoreMountOpts = mkOption {
+        type = types.listOf types.nonEmptyStr;
+        default = [
+          "ro"
+          "nodev"
+          "nosuid"
+        ];
+        description = ''
+          Defines the mount options used on a bind mount for the {file}`/nix/store`.
+          This affects the whole system except the nix store daemon, which will undo the bind mount.
+
+          `ro` enforces immutability of the Nix store.
+          The store daemon should already not put device mappers or suid binaries in the store,
+          meaning `nosuid` and `nodev` enforce what should already be the case.
+        '';
+      };
+
       systemdExecutable = mkOption {
         default = "/run/current-system/systemd/lib/systemd/systemd";
         type = types.str;
@@ -85,6 +103,9 @@ in
   config = {
 
     system.build.bootStage2 = bootStage2;
-
+    boot.nixStoreMountOpts = [
+      "nodev"
+      "nosuid"
+    ] ++ lib.optional config.boot.readOnlyNixStore "ro";
   };
 }