diff --git a/pkgs/by-name/gl/glycin-loaders/package.nix b/pkgs/by-name/gl/glycin-loaders/package.nix
index 06bc12716d63..a3588b6628a9 100644
--- a/pkgs/by-name/gl/glycin-loaders/package.nix
+++ b/pkgs/by-name/gl/glycin-loaders/package.nix
@@ -20,6 +20,7 @@
   ninja,
   pkg-config,
   rustc,
+  rustPlatform,
 }:
 
 stdenv.mkDerivation (finalAttrs: {
@@ -39,6 +40,8 @@ stdenv.mkDerivation (finalAttrs: {
     finalAttrs.passthru.glycinPathsPatch
   ];
 
+  cargoVendorDir = "vendor";
+
   nativeBuildInputs = [
     cargo
     gettext # for msgfmt
@@ -47,6 +50,7 @@ stdenv.mkDerivation (finalAttrs: {
     ninja
     pkg-config
     rustc
+    rustPlatform.cargoSetupHook
   ];
 
   buildInputs = [
@@ -68,6 +72,13 @@ stdenv.mkDerivation (finalAttrs: {
 
   strictDeps = true;
 
+  postPatch = ''
+    substituteInPlace loaders/meson.build \
+      --replace-fail "cargo_target_dir / rust_target / loader," "cargo_target_dir / '${stdenv.hostPlatform.rust.cargoShortTarget}' / rust_target / loader,"
+  '';
+
+  env.CARGO_BUILD_TARGET = stdenv.hostPlatform.rust.rustcTargetSpec;
+
   passthru = {
     updateScript = gnome.updateScript {
       attrPath = "glycin-loaders";