diff --git a/pkgs/development/python-modules/genai-prices/default.nix b/pkgs/development/python-modules/genai-prices/default.nix
index 7c58018d1233..c27015818d1d 100644
--- a/pkgs/development/python-modules/genai-prices/default.nix
+++ b/pkgs/development/python-modules/genai-prices/default.nix
@@ -7,20 +7,20 @@
   uv-build,
 
   # dependencies
-  httpx,
+  httpx2,
   pydantic,
 }:
 
 buildPythonPackage (finalAttrs: {
   pname = "genai-prices";
-  version = "0.0.61";
+  version = "0.0.62";
   pyproject = true;
 
   src = fetchFromGitHub {
     owner = "pydantic";
     repo = "genai-prices";
     tag = "v${finalAttrs.version}";
-    hash = "sha256-3w3V6uIeRBTpc2rtkVRVsLlWGzHHksklv3YyCw6/VEI=";
+    hash = "sha256-VUhJwv15cHqIsZc103aoTX1D8kzt+cy/jdHUi++0+/w=";
   };
 
   sourceRoot = "${finalAttrs.src.name}/packages/python";
@@ -30,7 +30,7 @@ buildPythonPackage (finalAttrs: {
   ];
 
   dependencies = [
-    httpx
+    httpx2
     pydantic
   ];
 
diff --git a/pkgs/development/python-modules/httpcore2/default.nix b/pkgs/development/python-modules/httpcore2/default.nix
new file mode 100644
index 000000000000..f7708b751017
--- /dev/null
+++ b/pkgs/development/python-modules/httpcore2/default.nix
@@ -0,0 +1,95 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+
+  # build-system
+  hatchling,
+  hatch-fancy-pypi-readme,
+  uv-dynamic-versioning,
+
+  # dependencies
+  certifi,
+  h11,
+
+  # optional dependencies
+  h2,
+  socksio,
+  trio,
+  anyio,
+
+  # tests
+  pytestCheckHook,
+  pytest-httpbin,
+  pytest-trio,
+
+  # reverse deps
+  httpx2,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "httpcore2";
+  version = "2.2.0";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "pydantic";
+    repo = "httpx2";
+    tag = "v${finalAttrs.version}";
+    hash = "sha256-RdoMDF5XVOkb4JCmytdF0JmBfTUcHuM1N+SD8r+RNiU=";
+  };
+
+  postPatch = ''
+    pushd src/httpcore2
+  '';
+
+  build-system = [
+    hatchling
+    hatch-fancy-pypi-readme
+    uv-dynamic-versioning
+  ];
+
+  dependencies = [
+    certifi
+    h11
+  ];
+
+  optional-dependencies = {
+    asyncio = [ anyio ];
+    http2 = [ h2 ];
+    socks = [ socksio ];
+    trio = [ trio ];
+  };
+
+  pythonImportsCheck = [
+    "httpcore2"
+  ];
+
+  preCheck = ''
+    popd
+  '';
+
+  nativeCheckInputs = [
+    pytestCheckHook
+    pytest-httpbin
+    pytest-trio
+  ]
+  ++ lib.concatAttrValues finalAttrs.passthru.optional-dependencies;
+
+  pytestFlags = [ "tests/httpcore2" ];
+
+  passthru.tests = {
+    inherit httpx2;
+  };
+
+  __darwinAllowLocalNetworking = true;
+  __structuredAttrs = true;
+
+  meta = {
+    description = "A next generation HTTP client for Python";
+    homepage = "https://github.com/pydantic/httpx2";
+    changelog = "https://github.com/pydantic/httpx2/blob/${finalAttrs.src.tag}/src/httpcore2/CHANGELOG.md";
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ hexa ];
+  };
+})
diff --git a/pkgs/development/python-modules/httpx2/default.nix b/pkgs/development/python-modules/httpx2/default.nix
new file mode 100644
index 000000000000..82f5a2acd0fd
--- /dev/null
+++ b/pkgs/development/python-modules/httpx2/default.nix
@@ -0,0 +1,122 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  isPyPy,
+  pythonOlder,
+
+  # build-system
+  hatchling,
+  hatch-fancy-pypi-readme,
+  uv-dynamic-versioning,
+
+  # dependencies
+  anyio,
+  certifi,
+  httpcore2,
+  idna,
+
+  # optional dependencies
+  brotli,
+  brotlicffi,
+  click,
+  h2,
+  pygments,
+  rich,
+  socksio,
+  zstandard,
+
+  # tests
+  chardet,
+  pytestCheckHook,
+  pytest-httpbin,
+  pytest-trio,
+  trustme,
+  uvicorn,
+
+  # reverse deps
+  httpx2,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "httpx2";
+  version = "2.2.0";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "pydantic";
+    repo = "httpx2";
+    tag = "v${finalAttrs.version}";
+    hash = "sha256-RdoMDF5XVOkb4JCmytdF0JmBfTUcHuM1N+SD8r+RNiU=";
+  };
+
+  postPatch = ''
+    pushd src/httpx2
+  '';
+
+  build-system = [
+    hatchling
+    hatch-fancy-pypi-readme
+    uv-dynamic-versioning
+  ];
+
+  dependencies = [
+    anyio
+    certifi
+    httpcore2
+    idna
+  ];
+
+  optional-dependencies = {
+    brotli = if isPyPy then [ brotlicffi ] else [ brotli ];
+    cli = [
+      click
+      pygments
+      rich
+    ];
+    http2 = [ h2 ];
+    socks = [ socksio ];
+    zstd = lib.optionals (pythonOlder "3.14") [ zstandard ];
+  };
+
+  pythonImportsCheck = [
+    "httpx2"
+  ];
+
+  preCheck = ''
+    popd
+  '';
+
+  nativeCheckInputs = [
+    chardet
+    pytestCheckHook
+    # pytest-httpbin
+    pytest-trio
+    trustme
+    uvicorn
+  ]
+  ++ lib.concatAttrValues finalAttrs.passthru.optional-dependencies;
+
+  pytestFlags = [ "tests/httpx2" ];
+
+  disabledTests = [
+    # network access
+    "test_async_proxy_close"
+    "test_sync_proxy_close"
+  ];
+
+  passthru.tests = {
+    inherit httpx2;
+  };
+
+  __darwinAllowLocalNetworking = true;
+  __structuredAttrs = true;
+
+  meta = {
+    description = "A next generation HTTP client for Python";
+    homepage = "https://github.com/pydantic/httpx2";
+    changelog = "https://github.com/pydantic/httpx2/blob/${finalAttrs.src.tag}/src/httpx2/CHANGELOG.md";
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ hexa ];
+  };
+})
diff --git a/pkgs/development/python-modules/pydantic-ai-slim/default.nix b/pkgs/development/python-modules/pydantic-ai-slim/default.nix
index a5848ca599fc..6e86318529ef 100644
--- a/pkgs/development/python-modules/pydantic-ai-slim/default.nix
+++ b/pkgs/development/python-modules/pydantic-ai-slim/default.nix
@@ -20,14 +20,14 @@
 
 buildPythonPackage (finalAttrs: {
   pname = "pydantic-ai-slim";
-  version = "1.102.0";
+  version = "1.103.0";
   pyproject = true;
 
   src = fetchFromGitHub {
     owner = "pydantic";
     repo = "pydantic-ai";
     tag = "v${finalAttrs.version}";
-    hash = "sha256-5mX4o/LqiLAUmn1WXV6RVf2KwDYJ5pxFPtF2meVFp1o=";
+    hash = "sha256-eWusMERC1yZ/BltZPcYkrBGpbdG0EyWZVwYDqMLD/kY=";
   };
 
   sourceRoot = "${finalAttrs.src.name}/pydantic_ai_slim";
diff --git a/pkgs/development/python-modules/pydantic-graph/default.nix b/pkgs/development/python-modules/pydantic-graph/default.nix
index ae1f19129b20..0ff62acf21b6 100644
--- a/pkgs/development/python-modules/pydantic-graph/default.nix
+++ b/pkgs/development/python-modules/pydantic-graph/default.nix
@@ -16,14 +16,14 @@
 
 buildPythonPackage (finalAttrs: {
   pname = "pydantic-graph";
-  version = "1.102.0";
+  version = "1.103.0";
   pyproject = true;
 
   src = fetchFromGitHub {
     owner = "pydantic";
     repo = "pydantic-ai";
     tag = "v${finalAttrs.version}";
-    hash = "sha256-5mX4o/LqiLAUmn1WXV6RVf2KwDYJ5pxFPtF2meVFp1o=";
+    hash = "sha256-eWusMERC1yZ/BltZPcYkrBGpbdG0EyWZVwYDqMLD/kY=";
   };
 
   sourceRoot = "${finalAttrs.src.name}/pydantic_graph";
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4ed1ce5b08d2..a18a31464372 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -7299,6 +7299,8 @@ self: super: with self; {
 
   httpcore = callPackage ../development/python-modules/httpcore { };
 
+  httpcore2 = callPackage ../development/python-modules/httpcore2 { };
+
   httpie = callPackage ../development/python-modules/httpie { };
 
   httpie-ntlm = callPackage ../development/python-modules/httpie-ntlm { };
@@ -7333,6 +7335,8 @@ self: super: with self; {
 
   httpx-ws = callPackage ../development/python-modules/httpx-ws { };
 
+  httpx2 = callPackage ../development/python-modules/httpx2 { };
+
   huawei-lte-api = callPackage ../development/python-modules/huawei-lte-api { };
 
   hueble = callPackage ../development/python-modules/hueble { };