diff --git a/pkgs/development/python-modules/pyfwup/default.nix b/pkgs/development/python-modules/pyfwup/default.nix
new file mode 100644
index 000000000000..2956c34b4685
--- /dev/null
+++ b/pkgs/development/python-modules/pyfwup/default.nix
@@ -0,0 +1,50 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+  pyusb,
+  tqdm,
+  libusb1,
+  setuptools,
+  setuptools-git-versioning,
+  pythonOlder,
+}:
+
+buildPythonPackage rec {
+  pname = "pyfwup";
+  version = "0.4.0";
+
+  pyproject = true;
+
+  disabled = pythonOlder "3.8";
+
+  src = fetchFromGitHub {
+    owner = "greatscottgadgets";
+    repo = "pyfwup";
+    rev = "refs/tags/${version}";
+    hash = "sha256-JSaAEGobdLqpSj9yvKrAsXfdkHpXSCcuGYRxz2QJqck=";
+  };
+
+  dependencies = [
+    pyusb
+    tqdm
+    libusb1
+  ];
+
+  build-system = [
+    setuptools
+    setuptools-git-versioning
+  ];
+
+  pythonImportsCheck = [
+    "fwup"
+    "fwup_utils"
+  ];
+
+  meta = {
+    description = "Python FirmWare UPgrader";
+    homepage = "https://github.com/greatscottgadgets/pyfwup";
+    license = lib.licenses.bsd3;
+    maintainers = [ lib.maintainers.msanft ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 6b4e3ae10ba7..d6400d36b332 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -11300,6 +11300,10 @@ self: super: with self; {
 
   pyfuse3 = callPackage ../development/python-modules/pyfuse3 { };
 
+  pyfwup = callPackage ../development/python-modules/pyfwup {
+    inherit (pkgs) libusb1;
+  };
+
   pyfxa = callPackage ../development/python-modules/pyfxa { };
 
   pyfzf = callPackage ../development/python-modules/pyfzf {