diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index a010651b51b0..6cfcdc82c07e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5313,7 +5313,10 @@ in {
 
   lzstring = callPackage ../development/python-modules/lzstring { };
 
-  m2crypto = callPackage ../development/python-modules/m2crypto { };
+  m2crypto = callPackage ../development/python-modules/m2crypto {
+    # https://gitlab.com/m2crypto/m2crypto/-/issues/310
+    openssl = pkgs.openssl_1_1;
+  };
 
   m2r = callPackage ../development/python-modules/m2r { };