diff --git a/pkgs/by-name/mm/mmseqs2/package.nix b/pkgs/by-name/mm/mmseqs2/package.nix
index ea16ae7f621f..71be0aefcd91 100644
--- a/pkgs/by-name/mm/mmseqs2/package.nix
+++ b/pkgs/by-name/mm/mmseqs2/package.nix
@@ -17,6 +17,7 @@
   zlib,
   bzip2,
   pkgsStatic,
+  runCommand,
 }:
 let
   # require static library, libzstd.a
@@ -76,6 +77,14 @@ stdenv.mkDerivation (finalAttrs: {
     rm -r $out/util/
   '';
 
+  passthru.tests = {
+    example = runCommand "mmseqs2-test" { } ''
+      ${lib.getExe finalAttrs.finalPackage} createdb ${finalAttrs.src}/examples/DB.fasta targetDB > $out
+      ${lib.getExe finalAttrs.finalPackage} createindex targetDB tmp >> $out
+      ${lib.getExe finalAttrs.finalPackage} easy-search ${finalAttrs.src}/examples/QUERY.fasta targetDB alnRes.m8 tmp >> $out
+    '';
+  };
+
   meta = with lib; {
     description = "Ultra fast and sensitive sequence search and clustering suite";
     mainProgram = "mmseqs";