diff --git a/pkgs/development/python-modules/rpcq/default.nix b/pkgs/development/python-modules/rpcq/default.nix
new file mode 100644
index 000000000000..671038c8b468
--- /dev/null
+++ b/pkgs/development/python-modules/rpcq/default.nix
@@ -0,0 +1,53 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, msgpack
+, numpy
+, pytest-asyncio
+, pytestCheckHook
+, python-rapidjson
+, pythonOlder
+, pyzmq
+, ruamel-yaml
+}:
+
+buildPythonPackage rec {
+  pname = "rpcq";
+  version = "3.9.2";
+
+  disabled = pythonOlder "3.6";
+
+  src = fetchFromGitHub {
+    owner = "rigetti";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "1vvf6y7459f8aamhkcxx36ajiai143s2vwg751x0dl0lx7hp3yn5";
+  };
+
+  propagatedBuildInputs = [
+    msgpack
+    python-rapidjson
+    pyzmq
+    ruamel-yaml
+  ];
+
+  checkInputs = [
+    numpy
+    pytest-asyncio
+    pytestCheckHook
+  ];
+
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "msgpack>=0.6,<1.0" "msgpack"
+  '';
+
+  pythonImportsCheck = [ "rpcq" ];
+
+  meta = with lib; {
+    description = "The RPC framework and message specification for rigetti Quantum Cloud services";
+    homepage = "https://github.com/rigetti/rpcq";
+    license = licenses.asl20;
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 70a534aae074..c009d0a95000 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -1465,6 +1465,8 @@ in {
 
   cirq-google = callPackage ../development/python-modules/cirq-google { };
 
+  cirq-rigetti = callPackage ../development/python-modules/cirq-rigetti { };
+
   cirq-pasqal = callPackage ../development/python-modules/cirq-pasqal { };
 
   cirq-web = callPackage ../development/python-modules/cirq-web { };
@@ -7918,6 +7920,8 @@ in {
 
   routes = callPackage ../development/python-modules/routes { };
 
+  rpcq = callPackage ../development/python-modules/rpcq { };
+
   rpdb = callPackage ../development/python-modules/rpdb { };
 
   rply = callPackage ../development/python-modules/rply { };