diff --git a/pkgs/development/python-modules/pyqldb/default.nix b/pkgs/development/python-modules/pyqldb/default.nix
new file mode 100644
index 000000000000..a6fd8665fd14
--- /dev/null
+++ b/pkgs/development/python-modules/pyqldb/default.nix
@@ -0,0 +1,32 @@
+{ lib, buildPythonPackage, fetchFromGitHub, boto3, amazon-ion, ionhash, pytestCheckHook }:
+
+buildPythonPackage rec {
+  pname = "pyqldb";
+  version = "3.2.2";
+
+  src = fetchFromGitHub {
+    owner = "awslabs";
+    repo = "amazon-qldb-driver-python";
+    rev = "v${version}";
+    sha256 = "sha256-TKf43+k428h8T6ye6mJrnK9D4J1xpIu0QacM7lWJF7w=";
+  };
+
+  propagatedBuildInputs = [ boto3 amazon-ion ionhash ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  preCheck = ''
+    export AWS_DEFAULT_REGION=us-east-1
+  '';
+
+  pytestFlagsArray = [ "tests/unit" ];
+
+  pythonImportsCheck = [ "pyqldb" ];
+
+  meta = with lib; {
+    description = "Python driver for Amazon QLDB";
+    homepage = "https://github.com/awslabs/amazon-qldb-driver-python";
+    license = licenses.asl20;
+    maintainers = [ maintainers.terlar ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4c66f942609a..751704f72787 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -7480,6 +7480,8 @@ in {
 
   pypytools = callPackage ../development/python-modules/pypytools { };
 
+  pyqldb = callPackage ../development/python-modules/pyqldb { };
+
   pyqrcode = callPackage ../development/python-modules/pyqrcode { };
 
   pyqt-builder = callPackage ../development/python-modules/pyqt-builder { };