diff --git a/pkgs/servers/matrix-synapse/default.nix b/pkgs/servers/matrix-synapse/default.nix
index f18c6f83ffc9..04700a9e209e 100644
--- a/pkgs/servers/matrix-synapse/default.nix
+++ b/pkgs/servers/matrix-synapse/default.nix
@@ -1,5 +1,6 @@
 { lib, stdenv, python3, openssl
 , enableSystemd ? stdenv.isLinux, nixosTests
+, enableRedis ? false
 }:
 
 with python3.pkgs;
@@ -9,11 +10,11 @@ let
 in
 buildPythonApplication rec {
   pname = "matrix-synapse";
-  version = "1.21.2";
+  version = "1.22.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "061b2mpdzqxyks1kj3p7xmw8i4akqfd2s9vb7v8w27k2qpcw7528";
+    sha256 = "0dl4a5zirrjabbfibl9vj4zb16md11kqkz2v9l299gxbwwvzqc39";
   };
 
   patches = [
@@ -53,13 +54,15 @@ buildPythonApplication rec {
     typing-extensions
     authlib
     pyjwt
-  ] ++ lib.optional enableSystemd systemd;
+  ] ++ lib.optional enableSystemd systemd
+    ++ lib.optional enableRedis hiredis;
 
   checkInputs = [ mock parameterized openssl ];
 
   doCheck = !stdenv.isDarwin;
 
   checkPhase = ''
+    ${lib.optionalString (!enableRedis) "rm -r tests/replication # these tests need the optional dependency 'hiredis'"}
     PYTHONPATH=".:$PYTHONPATH" ${python3.interpreter} -m twisted.trial tests
   '';