diff --git a/pkgs/development/python-modules/pyedflib/default.nix b/pkgs/development/python-modules/pyedflib/default.nix
new file mode 100644
index 000000000000..a83fe89795b0
--- /dev/null
+++ b/pkgs/development/python-modules/pyedflib/default.nix
@@ -0,0 +1,55 @@
+{
+  lib,
+  buildPythonPackage,
+  fetchFromGitHub,
+
+  # build-system
+  cython,
+  numpy,
+  setuptools,
+
+  # tests
+  pytestCheckHook,
+}:
+
+buildPythonPackage rec {
+  pname = "pyedflib";
+  version = "0.1.38";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "holgern";
+    repo = "pyedflib";
+    tag = "v${version}";
+    hash = "sha256-sj2O5ISAy12u4GdtucLaRfOeSA6o6FJpZWTyiLq5B3U=";
+  };
+
+  build-system = [
+    cython
+    numpy
+    setuptools
+  ];
+
+  pythonImportsCheck = [
+    "pyedflib"
+  ];
+
+  # Otherwise, the module is imported from source and lacks the compiled artifacts
+  # By moving to the pyedflib directory, python imports the installed package instead of the module
+  # from the local files
+  preCheck = ''
+    cd pyedflib
+  '';
+
+  nativeCheckInputs = [
+    pytestCheckHook
+  ];
+
+  meta = {
+    description = "Python library to read/write EDF+/BDF+ files based on EDFlib";
+    homepage = "https://github.com/holgern/pyedflib";
+    changelog = "https://github.com/holgern/pyedflib/releases/tag/v${version}";
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ GaetanLepage ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index c7db18e65452..b5a48837f234 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -11619,6 +11619,8 @@ self: super: with self; {
 
   pyecowitt = callPackage ../development/python-modules/pyecowitt { };
 
+  pyedflib = callPackage ../development/python-modules/pyedflib { };
+
   pyedimax = callPackage ../development/python-modules/pyedimax { };
 
   pyee = callPackage ../development/python-modules/pyee { };