diff --git a/pkgs/development/python-modules/pyopenssl/default.nix b/pkgs/development/python-modules/pyopenssl/default.nix
index 688731033a98..3b225ad721ea 100644
--- a/pkgs/development/python-modules/pyopenssl/default.nix
+++ b/pkgs/development/python-modules/pyopenssl/default.nix
@@ -64,12 +64,12 @@ in
 
 buildPythonPackage rec {
   pname = "pyopenssl";
-  version = "20.0.1";
+  version = "21.0.0";
 
   src = fetchPypi {
     pname = "pyOpenSSL";
     inherit version;
-    sha256 = "4c231c759543ba02560fcd2480c48dcec4dae34c9da7d3747c508227e0624b51";
+    sha256 = "5e2d8c5e46d0d865ae933bef5230090bdaf5506281e9eec60fa250ee80600cb3";
   };
 
   outputs = [ "out" "dev" ];