diff --git a/pkgs/by-name/f3/f3d/package.nix b/pkgs/by-name/f3/f3d/package.nix
index 7ffd861b9508..9ca7fcb6e3ae 100644
--- a/pkgs/by-name/f3/f3d/package.nix
+++ b/pkgs/by-name/f3/f3d/package.nix
@@ -97,8 +97,5 @@ stdenv.mkDerivation rec {
     ];
     platforms = with platforms; unix;
     mainProgram = "f3d";
-    # error: use of undeclared identifier 'NSMenuItem'
-    # adding AppKit does not solve it
-    broken = with stdenv.hostPlatform; isDarwin && isx86_64;
   };
 }
diff --git a/pkgs/by-name/ge/geant4/package.nix b/pkgs/by-name/ge/geant4/package.nix
index 923e9c3536fe..d06e2b8e39f3 100644
--- a/pkgs/by-name/ge/geant4/package.nix
+++ b/pkgs/by-name/ge/geant4/package.nix
@@ -141,7 +141,6 @@ stdenv.mkDerivation rec {
   '';
 
   meta = with lib; {
-    broken = (stdenv.hostPlatform.isLinux && stdenv.hostPlatform.isAarch64);
     description = "Toolkit for the simulation of the passage of particles through matter";
     longDescription = ''
       Geant4 is a toolkit for the simulation of the passage of particles through matter.
diff --git a/pkgs/development/python-modules/argostranslate/default.nix b/pkgs/development/python-modules/argostranslate/default.nix
index f3121e90dd5b..512ebcc3449c 100644
--- a/pkgs/development/python-modules/argostranslate/default.nix
+++ b/pkgs/development/python-modules/argostranslate/default.nix
@@ -1,6 +1,5 @@
 {
   lib,
-  stdenv,
   buildPythonPackage,
   fetchPypi,
   pytestCheckHook,
@@ -60,7 +59,5 @@ buildPythonPackage rec {
     homepage = "https://www.argosopentech.com";
     license = lib.licenses.mit;
     maintainers = with lib.maintainers; [ misuzu ];
-    # Segfaults at import
-    broken = stdenv.hostPlatform.isDarwin && stdenv.hostPlatform.isx86_64;
   };
 }
diff --git a/pkgs/development/python-modules/bytewax/default.nix b/pkgs/development/python-modules/bytewax/default.nix
index a1963deb433f..8cc88f937900 100644
--- a/pkgs/development/python-modules/bytewax/default.nix
+++ b/pkgs/development/python-modules/bytewax/default.nix
@@ -1,6 +1,5 @@
 {
   lib,
-  stdenv,
   buildPythonPackage,
   fetchFromGitHub,
   pythonOlder,
@@ -106,7 +105,5 @@ buildPythonPackage rec {
       mslingsby
       kfollesdal
     ];
-    # mismatched type expected u8, found i8
-    broken = stdenv.hostPlatform.isAarch64;
   };
 }
diff --git a/pkgs/development/python-modules/cgal/default.nix b/pkgs/development/python-modules/cgal/default.nix
index cdebc76a1827..fe91cb60505c 100644
--- a/pkgs/development/python-modules/cgal/default.nix
+++ b/pkgs/development/python-modules/cgal/default.nix
@@ -83,7 +83,5 @@ buildPythonPackage rec {
     homepage = "https://github.com/CGAL/cgal-swig-bindings";
     license = lib.licenses.gpl3Plus;
     maintainers = with lib.maintainers; [ pbsds ];
-    # error: no template named 'unary_function' in namespace 'boost::functional::detail'
-    broken = stdenv.hostPlatform.isDarwin;
   };
 }
diff --git a/pkgs/development/python-modules/clldutils/default.nix b/pkgs/development/python-modules/clldutils/default.nix
index e0d3e1e30e5f..0018a2744d9c 100644
--- a/pkgs/development/python-modules/clldutils/default.nix
+++ b/pkgs/development/python-modules/clldutils/default.nix
@@ -64,7 +64,5 @@ buildPythonPackage rec {
     homepage = "https://github.com/clld/clldutils";
     license = licenses.asl20;
     maintainers = with maintainers; [ melling ];
-    # TypeError: EnumSymbol.__init__() missing 2 required positional arguments: 'value' and 'description'
-    broken = true;
   };
 }
diff --git a/pkgs/development/python-modules/etebase/default.nix b/pkgs/development/python-modules/etebase/default.nix
index 420f6186b36e..119ab454014c 100644
--- a/pkgs/development/python-modules/etebase/default.nix
+++ b/pkgs/development/python-modules/etebase/default.nix
@@ -1,6 +1,5 @@
 {
   lib,
-  stdenv,
   fetchFromGitHub,
   buildPythonPackage,
   rustPlatform,
@@ -75,7 +74,6 @@ buildPythonPackage rec {
   };
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     homepage = "https://www.etebase.com/";
     description = "Python client library for Etebase";
     license = licenses.bsd3;
diff --git a/pkgs/development/python-modules/gb-io/default.nix b/pkgs/development/python-modules/gb-io/default.nix
index 927315466931..32890d833233 100644
--- a/pkgs/development/python-modules/gb-io/default.nix
+++ b/pkgs/development/python-modules/gb-io/default.nix
@@ -1,12 +1,10 @@
 {
-  stdenv,
   lib,
   fetchFromGitHub,
   buildPythonPackage,
   rustPlatform,
   cargo,
   rustc,
-  setuptools-rust,
   unittestCheckHook,
 }:
 
@@ -43,7 +41,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "gb_io" ];
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     homepage = "https://github.com/althonos/gb-io.py";
     description = "Python interface to gb-io, a fast GenBank parser written in Rust";
     license = licenses.mit;
diff --git a/pkgs/development/python-modules/greeclimate/default.nix b/pkgs/development/python-modules/greeclimate/default.nix
index 5679c3145d46..ee705a9087d9 100644
--- a/pkgs/development/python-modules/greeclimate/default.nix
+++ b/pkgs/development/python-modules/greeclimate/default.nix
@@ -1,5 +1,4 @@
 {
-  stdenv,
   lib,
   buildPythonPackage,
   pythonOlder,
@@ -63,7 +62,6 @@ buildPythonPackage rec {
   ];
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     description = "Discover, connect and control Gree based minisplit systems";
     homepage = "https://github.com/cmroche/greeclimate";
     changelog = "https://github.com/cmroche/greeclimate/blob/${src.rev}/CHANGELOG.md";
diff --git a/pkgs/development/python-modules/imagecodecs-lite/default.nix b/pkgs/development/python-modules/imagecodecs-lite/default.nix
index b21b80c7c694..1e2f172da593 100644
--- a/pkgs/development/python-modules/imagecodecs-lite/default.nix
+++ b/pkgs/development/python-modules/imagecodecs-lite/default.nix
@@ -1,5 +1,4 @@
 {
-  stdenv,
   lib,
   fetchPypi,
   buildPythonPackage,
@@ -29,8 +28,6 @@ buildPythonPackage rec {
   '';
 
   meta = with lib; {
-    broken =
-      (stdenv.hostPlatform.isLinux && stdenv.hostPlatform.isAarch64) || stdenv.hostPlatform.isDarwin;
     description = "Block-oriented, in-memory buffer transformation, compression, and decompression functions";
     homepage = "https://www.lfd.uci.edu/~gohlke/";
     maintainers = [ maintainers.tbenst ];
diff --git a/pkgs/development/python-modules/mayavi/default.nix b/pkgs/development/python-modules/mayavi/default.nix
index 046ef18f3628..540b401fcbe6 100644
--- a/pkgs/development/python-modules/mayavi/default.nix
+++ b/pkgs/development/python-modules/mayavi/default.nix
@@ -11,7 +11,6 @@
   pyqt5,
   pythonOlder,
   pythonAtLeast,
-  stdenv,
   traitsui,
   vtk,
   wrapQtAppsHook,
@@ -60,8 +59,5 @@ buildPythonPackage rec {
     license = licenses.bsdOriginal;
     maintainers = with maintainers; [ ];
     mainProgram = "mayavi2";
-    # Fails during stripping with:
-    # The file was not recognized as a valid object file
-    broken = stdenv.hostPlatform.isDarwin;
   };
 }
diff --git a/pkgs/development/python-modules/open-clip-torch/default.nix b/pkgs/development/python-modules/open-clip-torch/default.nix
index d9b06c1d2130..bef5ea802b4b 100644
--- a/pkgs/development/python-modules/open-clip-torch/default.nix
+++ b/pkgs/development/python-modules/open-clip-torch/default.nix
@@ -95,7 +95,5 @@ buildPythonPackage rec {
     license = lib.licenses.asl20;
     maintainers = with lib.maintainers; [ iynaix ];
     mainProgram = "open-clip";
-    # Segfaults during pythonImportsCheck phase
-    broken = stdenv.hostPlatform.system == "x86_64-darwin";
   };
 }
diff --git a/pkgs/development/python-modules/osc/default.nix b/pkgs/development/python-modules/osc/default.nix
index bb16aa7d40e0..d45d7ff4f09e 100644
--- a/pkgs/development/python-modules/osc/default.nix
+++ b/pkgs/development/python-modules/osc/default.nix
@@ -1,5 +1,4 @@
 {
-  stdenv,
   bashInteractive,
   buildPythonPackage,
   cryptography,
@@ -49,7 +48,6 @@ buildPythonPackage rec {
   preCheck = "HOME=$TOP/tmp";
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     homepage = "https://github.com/openSUSE/osc";
     description = "opensuse-commander with svn like handling";
     mainProgram = "osc";
diff --git a/pkgs/development/python-modules/pint-pandas/default.nix b/pkgs/development/python-modules/pint-pandas/default.nix
index 6bd27a237e7f..44688b331958 100644
--- a/pkgs/development/python-modules/pint-pandas/default.nix
+++ b/pkgs/development/python-modules/pint-pandas/default.nix
@@ -1,5 +1,4 @@
 {
-  stdenv,
   lib,
   buildPythonPackage,
   fetchFromGitHub,
@@ -9,6 +8,7 @@
   wheel,
   pint,
   pandas,
+  packaging,
   pytestCheckHook,
 }:
 
@@ -35,12 +35,12 @@ buildPythonPackage rec {
   dependencies = [
     pint
     pandas
+    packaging
   ];
 
   nativeCheckInputs = [ pytestCheckHook ];
 
   meta = {
-    broken = stdenv.hostPlatform.isDarwin;
     description = "Pandas support for pint";
     license = lib.licenses.bsd3;
     homepage = "https://github.com/hgrecco/pint-pandas";
diff --git a/pkgs/development/python-modules/pylibjpeg-openjpeg/default.nix b/pkgs/development/python-modules/pylibjpeg-openjpeg/default.nix
index ddd616eb0bfe..d4de581a112f 100644
--- a/pkgs/development/python-modules/pylibjpeg-openjpeg/default.nix
+++ b/pkgs/development/python-modules/pylibjpeg-openjpeg/default.nix
@@ -72,9 +72,7 @@ buildPythonPackage rec {
     changelog = "https://github.com/pydicom/pylibjpeg-openjpeg/releases/tag/v${version}";
     license = [ lib.licenses.mit ];
     maintainers = with lib.maintainers; [ bcdarwin ];
-    # x86-linux: test_encode.py::TestEncodeBuffer failures
-    # darwin: numerous test failures, seemingly due to issues setting up test data
-    broken =
-      (stdenv.hostPlatform.isAarch64 && stdenv.hostPlatform.isLinux) || stdenv.hostPlatform.isDarwin;
+    # darwin: numerous test failures, test dependency pydicom is marked as unsupported
+    broken = stdenv.hostPlatform.isDarwin;
   };
 }
diff --git a/pkgs/development/python-modules/pysequoia/default.nix b/pkgs/development/python-modules/pysequoia/default.nix
index aa1256a89d9e..852f1d64433c 100644
--- a/pkgs/development/python-modules/pysequoia/default.nix
+++ b/pkgs/development/python-modules/pysequoia/default.nix
@@ -58,7 +58,5 @@ buildPythonPackage rec {
     homepage = "https://sequoia-pgp.gitlab.io/pysequoia";
     license = licenses.asl20;
     maintainers = with maintainers; [ doronbehar ];
-    # Broken since the 0.1.20 update according to ofborg. The errors are not clear...
-    broken = stdenv.hostPlatform.isDarwin;
   };
 }
diff --git a/pkgs/development/python-modules/pysptk/default.nix b/pkgs/development/python-modules/pysptk/default.nix
index e148d8af8b06..1e070413f8f0 100644
--- a/pkgs/development/python-modules/pysptk/default.nix
+++ b/pkgs/development/python-modules/pysptk/default.nix
@@ -1,6 +1,5 @@
 {
   lib,
-  stdenv,
   buildPythonPackage,
   cython,
   decorator,
@@ -8,6 +7,7 @@
   numpy,
   pythonOlder,
   scipy,
+  setuptools,
   six,
 }:
 
@@ -31,6 +31,7 @@ buildPythonPackage rec {
     decorator
     numpy
     scipy
+    setuptools
     six
   ];
 
@@ -40,7 +41,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "pysptk" ];
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     description = "Wrapper for Speech Signal Processing Toolkit (SPTK)";
     homepage = "https://pysptk.readthedocs.io/";
     license = licenses.mit;
diff --git a/pkgs/development/python-modules/pyvlx/default.nix b/pkgs/development/python-modules/pyvlx/default.nix
index 9a746bb96d1e..bff1a08f380f 100644
--- a/pkgs/development/python-modules/pyvlx/default.nix
+++ b/pkgs/development/python-modules/pyvlx/default.nix
@@ -1,6 +1,5 @@
 {
   lib,
-  stdenv,
   buildPythonPackage,
   fetchFromGitHub,
   pytestCheckHook,
@@ -47,6 +46,5 @@ buildPythonPackage rec {
     changelog = "https://github.com/Julius2342/pyvlx/releases/tag/${version}";
     license = licenses.lgpl2Only;
     maintainers = with maintainers; [ fab ];
-    broken = stdenv.hostPlatform.isDarwin;
   };
 }
diff --git a/pkgs/development/python-modules/stups-fullstop/default.nix b/pkgs/development/python-modules/stups-fullstop/default.nix
index a2662d754c55..b071b6a405af 100644
--- a/pkgs/development/python-modules/stups-fullstop/default.nix
+++ b/pkgs/development/python-modules/stups-fullstop/default.nix
@@ -15,7 +15,7 @@ buildPythonPackage rec {
   pname = "stups-fullstop";
   version = "1.1.31";
   format = "setuptools";
-  disabled = !isPy3k;
+  disabled = !isPy3k || pythonAtLeast "3.11"; # Uses regex patterns deprecated in 3.9, errors in 3.11+
 
   src = fetchFromGitHub {
     owner = "zalando-stups";
@@ -44,8 +44,5 @@ buildPythonPackage rec {
     homepage = "https://github.com/zalando-stups/stups-fullstop-cli";
     license = licenses.asl20;
     maintainers = [ maintainers.mschuwalow ];
-    # Uses regex patterns deprecated in 3.9:
-    #     re.error: global flags not at the start of the expression at ...
-    broken = pythonAtLeast "3.11";
   };
 }
diff --git a/pkgs/development/python-modules/tabcmd/default.nix b/pkgs/development/python-modules/tabcmd/default.nix
index 0cbc0acf4612..12911b3552fc 100644
--- a/pkgs/development/python-modules/tabcmd/default.nix
+++ b/pkgs/development/python-modules/tabcmd/default.nix
@@ -90,7 +90,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "tabcmd" ];
 
   meta = with lib; {
-    broken = true;
     description = "Command line client for working with Tableau Server";
     homepage = "https://github.com/tableau/tabcmd";
     changelog = "https://github.com/tableau/tabcmd/releases/tag/v${version}";
diff --git a/pkgs/development/python-modules/type-infer/default.nix b/pkgs/development/python-modules/type-infer/default.nix
index 97d8e1f48614..4ce88d3b049f 100644
--- a/pkgs/development/python-modules/type-infer/default.nix
+++ b/pkgs/development/python-modules/type-infer/default.nix
@@ -2,6 +2,7 @@
   lib,
   buildPythonPackage,
   pythonOlder,
+  pythonAtLeast,
   fetchFromGitHub,
   poetry-core,
   colorlog,
@@ -36,7 +37,7 @@ buildPythonPackage {
   inherit version;
   pyproject = true;
 
-  disabled = pythonOlder "3.8";
+  disabled = pythonOlder "3.8" || pythonAtLeast "3.13";
 
   src = fetchFromGitHub {
     owner = "mindsdb";
@@ -87,7 +88,5 @@ buildPythonPackage {
     homepage = "https://github.com/mindsdb/type_infer";
     license = licenses.gpl3Only;
     maintainers = with maintainers; [ mbalatsko ];
-    # ModuleNotFoundError: No module named 'imghdr', unrelated
-    broken = true;
   };
 }
diff --git a/pkgs/development/python-modules/zeroc-ice/default.nix b/pkgs/development/python-modules/zeroc-ice/default.nix
index 7d6cc236f8f4..9217dddaa6cf 100644
--- a/pkgs/development/python-modules/zeroc-ice/default.nix
+++ b/pkgs/development/python-modules/zeroc-ice/default.nix
@@ -1,5 +1,4 @@
 {
-  stdenv,
   lib,
   buildPythonPackage,
   fetchPypi,
@@ -29,7 +28,6 @@ buildPythonPackage rec {
   pythonImportsCheck = [ "Ice" ];
 
   meta = with lib; {
-    broken = stdenv.hostPlatform.isDarwin;
     homepage = "https://zeroc.com/";
     license = licenses.gpl2;
     description = "Comprehensive RPC framework with support for Python, C++, .NET, Java, JavaScript and more";