diff --git a/pkgs/applications/radio/gnuradio/wrapper.nix b/pkgs/applications/radio/gnuradio/wrapper.nix
index 10896f19f1c1..d555d23e2fc4 100644
--- a/pkgs/applications/radio/gnuradio/wrapper.nix
+++ b/pkgs/applications/radio/gnuradio/wrapper.nix
@@ -64,10 +64,14 @@ let
   pythonPkgs =
     extraPythonPackages
     ++ [ (unwrapped.python.pkgs.toPythonModule unwrapped) ]
-    ++ unwrapped.passthru.uhd.pythonPath
-    ++ lib.optionals (unwrapped.passthru.uhd.pythonPath != [ ]) [
-      (unwrapped.python.pkgs.toPythonModule unwrapped.passthru.uhd)
-    ]
+    ++ lib.optionals (unwrapped.hasFeature "gr-uhd") (
+      unwrapped.passthru.uhd.pythonPath
+      # Check if uhd was built with python support, which means it should
+      # be added as a python module too.
+      ++ lib.optionals (unwrapped.passthru.uhd.pythonPath != [ ]) [
+        (unwrapped.python.pkgs.toPythonModule unwrapped.passthru.uhd)
+      ]
+    )
     # Add the extraPackages as python modules as well
     ++ (map unwrapped.python.pkgs.toPythonModule extraPackages)
     ++ lib.flatten (