diff --git a/pkgs/development/libraries/pixman/default.nix b/pkgs/development/libraries/pixman/default.nix
index 8bc8934d9561..121bb03f4cac 100644
--- a/pkgs/development/libraries/pixman/default.nix
+++ b/pkgs/development/libraries/pixman/default.nix
@@ -1,6 +1,8 @@
 { lib
 , stdenv
 , fetchurl
+, meson
+, ninja
 , pkg-config
 , libpng
 , glib /*just passthru*/
@@ -12,29 +14,37 @@
 , tigervnc
 , wlroots
 , xwayland
+
+, gitUpdater
 }:
 
 stdenv.mkDerivation rec {
   pname = "pixman";
-  version = "0.42.2";
+  version = "0.43.0";
 
   src = fetchurl {
     urls = [
       "mirror://xorg/individual/lib/${pname}-${version}.tar.gz"
       "https://cairographics.org/releases/${pname}-${version}.tar.gz"
     ];
-    hash = "sha256-6hSA762i/ZSLx1Nm98NJ4cltMpfQmj/mJibjjiNKYl4=";
+    hash = "sha256-plwoIJhY+xa+5Q2AnID5Co5BXA5P2DIQeKGCJ4WlVgo=";
   };
 
   separateDebugInfo = !stdenv.hostPlatform.isStatic;
 
-  nativeBuildInputs = [ pkg-config ];
+  nativeBuildInputs = [ meson ninja pkg-config ];
 
   buildInputs = [ libpng ];
 
-  configureFlags = lib.optional stdenv.isAarch32 "--disable-arm-iwmmxt"
-    # Disable until https://gitlab.freedesktop.org/pixman/pixman/-/issues/46 is resolved
-    ++ lib.optional (stdenv.isAarch64 && !stdenv.cc.isGNU) "--disable-arm-a64-neon";
+  # Default "enabled" value attempts to enable CPU features on all
+  # architectures and requires used to disable them:
+  #   https://gitlab.freedesktop.org/pixman/pixman/-/issues/88
+  mesonAutoFeatures = "auto";
+  mesonFlags = [
+    "-Diwmmxt=disabled"
+  ]
+  # Disable until https://gitlab.freedesktop.org/pixman/pixman/-/issues/46 is resolved
+  ++ lib.optional (stdenv.isAarch64 && !stdenv.cc.isGNU) "-Da64-neon=disabled";
 
   preConfigure = ''
     # https://gitlab.freedesktop.org/pixman/pixman/-/issues/62
@@ -47,8 +57,14 @@ stdenv.mkDerivation rec {
 
   postInstall = glib.flattenInclude;
 
-  passthru.tests = {
-    inherit cairo qemu scribus tigervnc wlroots xwayland;
+  passthru = {
+    tests = {
+      inherit cairo qemu scribus tigervnc wlroots xwayland;
+    };
+    updateScript = gitUpdater {
+      url = "https://gitlab.freedesktop.org/pixman/pixman.git";
+      rev-prefix = "pixman-";
+    };
   };
 
   meta = with lib; {