diff --git a/pkgs/development/python-modules/snakemake-storage-plugin-s3/default.nix b/pkgs/development/python-modules/snakemake-storage-plugin-s3/default.nix
index 3b8529714ed8..d757a619609a 100644
--- a/pkgs/development/python-modules/snakemake-storage-plugin-s3/default.nix
+++ b/pkgs/development/python-modules/snakemake-storage-plugin-s3/default.nix
@@ -2,24 +2,33 @@
   lib,
   buildPythonPackage,
   fetchFromGitHub,
+
+  # build-system
+  poetry-core,
+
+  # dependencies
   boto3,
   botocore,
-  poetry-core,
-  snakemake,
-  snakemake-interface-storage-plugins,
   snakemake-interface-common,
+  snakemake-interface-storage-plugins,
   urllib3,
+
+  # tests
+  pytestCheckHook,
+  snakemake,
+  writableTmpDirAsHomeHook,
 }:
 
-buildPythonPackage rec {
+buildPythonPackage (finalAttrs: {
   pname = "snakemake-storage-plugin-s3";
   version = "0.3.6";
   pyproject = true;
+  __structuredAttrs = true;
 
   src = fetchFromGitHub {
     owner = "snakemake";
     repo = "snakemake-storage-plugin-s3";
-    tag = "v${version}";
+    tag = "v${finalAttrs.version}";
     hash = "sha256-hvyQ6V6POUBWTCWt9moQlH0RgSM4J36kjbXK4TtO8Bo=";
   };
 
@@ -33,15 +42,31 @@ buildPythonPackage rec {
     urllib3
   ];
 
-  nativeCheckInputs = [ snakemake ];
-
   pythonImportsCheck = [ "snakemake_storage_plugin_s3" ];
 
+  nativeCheckInputs = [
+    pytestCheckHook
+    snakemake
+    writableTmpDirAsHomeHook
+  ];
+
+  enabledTestPaths = [ "tests/tests.py" ];
+
+  disabledTests = [
+    # Requires internet access
+    "test_storage"
+
+    # snakemake_interface_common.exceptions.WorkflowError: Failed to create local storage prefix .snakemake/storage/s3
+    # PermissionError: [Errno 13] Permission denied: '.snakemake'
+    "test_group_workflow"
+    "test_simple_workflow"
+  ];
+
   meta = {
     description = "Snakemake storage plugin for S3 API storage (AWS S3, MinIO, etc.)";
     homepage = "https://github.com/snakemake/snakemake-storage-plugin-s3";
-    changelog = "https://github.com/snakemake/snakemake-storage-plugin-s3/releases/tag/${src.tag}";
+    changelog = "https://github.com/snakemake/snakemake-storage-plugin-s3/releases/tag/${finalAttrs.src.tag}";
     license = lib.licenses.mit;
     maintainers = with lib.maintainers; [ veprbl ];
   };
-}
+})