diff --git a/pkgs/servers/sql/mariadb/default.nix b/pkgs/servers/sql/mariadb/default.nix
index 232b10706468..3a8dc0594415 100644
--- a/pkgs/servers/sql/mariadb/default.nix
+++ b/pkgs/servers/sql/mariadb/default.nix
@@ -120,10 +120,16 @@ let
         prePatch = ''
           sed -i 's,[^"]*/var/log,/var/log,g' storage/mroonga/vendor/groonga/CMakeLists.txt
         '';
+        env = lib.optionalAttrs (stdenv.hostPlatform.isLinux && !stdenv.hostPlatform.isGnu) {
+          # MariaDB uses non-POSIX fopen64, which musl only conditionally defines.
+          NIX_CFLAGS_COMPILE = "-D_LARGEFILE64_SOURCE";
+        };
 
         patches =
           [
             ./patch/cmake-includedir.patch
+            # patch for musl compatibility
+            ./patch/include-cstdint-full.patch
           ]
           # Fixes a build issue as documented on
           # https://jira.mariadb.org/browse/MDEV-26769?focusedCommentId=206073&page=com.atlassian.jira.plugin.system.issuetabpanels:comment-tabpanel#comment-206073
diff --git a/pkgs/servers/sql/mariadb/patch/include-cstdint-full.patch b/pkgs/servers/sql/mariadb/patch/include-cstdint-full.patch
new file mode 100644
index 000000000000..b2697df992af
--- /dev/null
+++ b/pkgs/servers/sql/mariadb/patch/include-cstdint-full.patch
@@ -0,0 +1,48 @@
+diff --git a/storage/rocksdb/rocksdb/table/block_based/data_block_hash_index.h b/storage/rocksdb/rocksdb/table/block_based/data_block_hash_index.h
+index f356395..3215221 100644
+--- a/storage/rocksdb/rocksdb/table/block_based/data_block_hash_index.h
++++ b/storage/rocksdb/rocksdb/table/block_based/data_block_hash_index.h
+@@ -5,6 +5,7 @@
+ 
+ #pragma once
+ 
++#include <cstdint>
+ #include <string>
+ #include <vector>
+ 
+diff --git a/storage/rocksdb/rocksdb/util/string_util.h b/storage/rocksdb/rocksdb/util/string_util.h
+index a761be6..064d059 100644
+--- a/storage/rocksdb/rocksdb/util/string_util.h
++++ b/storage/rocksdb/rocksdb/util/string_util.h
+@@ -6,6 +6,7 @@
+ 
+ #pragma once
+ 
++#include <cstdint>
+ #include <sstream>
+ #include <string>
+ #include <unordered_map>
+diff --git a/storage/rocksdb/rocksdb/include/rocksdb/utilities/checkpoint.h b/storage/rocksdb/rocksdb/include/rocksdb/utilities/checkpoint.h
+index c7f93b4..3c2ab80 100644
+--- a/storage/rocksdb/rocksdb/include/rocksdb/utilities/checkpoint.h
++++ b/storage/rocksdb/rocksdb/include/rocksdb/utilities/checkpoint.h
+@@ -8,6 +8,7 @@
+ #pragma once
+ #ifndef ROCKSDB_LITE
+ 
++#include <cstdint>
+ #include <string>
+ #include <vector>
+ #include "rocksdb/status.h"
+diff --git a/storage/rocksdb/rocksdb/db/compaction/compaction_iteration_stats.h b/storage/rocksdb/rocksdb/db/compaction/compaction_iteration_stats.h
+index 963c1d8..8d70309 100644
+--- a/storage/rocksdb/rocksdb/db/compaction/compaction_iteration_stats.h
++++ b/storage/rocksdb/rocksdb/db/compaction/compaction_iteration_stats.h
+@@ -6,6 +6,7 @@
+ #pragma once
+ 
+ #include "rocksdb/rocksdb_namespace.h"
++#include <cstdint>
+ 
+ struct CompactionIterationStats {
+   // Compaction statistics