diff --git a/pkgs/development/libraries/libspatialindex/default.nix b/pkgs/development/libraries/libspatialindex/default.nix
index 0f9d958ab8c9..e8cce6133c1f 100644
--- a/pkgs/development/libraries/libspatialindex/default.nix
+++ b/pkgs/development/libraries/libspatialindex/default.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, fetchFromGitHub, cmake }:
+{ lib, stdenv, fetchFromGitHub, cmake, fixDarwinDylibNames }:
 
 stdenv.mkDerivation (finalAttrs: {
   pname = "libspatialindex";
@@ -15,7 +15,7 @@ stdenv.mkDerivation (finalAttrs: {
     patchShebangs test/
   '';
 
-  nativeBuildInputs = [ cmake ];
+  nativeBuildInputs = [ cmake ] ++ lib.optional stdenv.isDarwin fixDarwinDylibNames;
 
   cmakeFlags = [
     (lib.cmakeBool "BUILD_TESTING" finalAttrs.finalPackage.doCheck)
@@ -31,6 +31,10 @@ stdenv.mkDerivation (finalAttrs: {
 
   doCheck = true;
 
+  postFixup = lib.optionalString stdenv.isDarwin ''
+    install_name_tool -change "@rpath/libspatialindex.7.dylib" "$out/lib/libspatialindex.7.dylib" $out/lib/libspatialindex_c.dylib
+  '';
+
   meta = with lib; {
     description = "Extensible spatial index library in C++";
     homepage = "https://libspatialindex.org";