diff --git a/pkgs/by-name/ca/cargo-nextest/no-dtrace-macos.patch b/pkgs/by-name/ca/cargo-nextest/no-dtrace-macos.patch
new file mode 100644
index 000000000000..ffd49c79d4dc
--- /dev/null
+++ b/pkgs/by-name/ca/cargo-nextest/no-dtrace-macos.patch
@@ -0,0 +1,62 @@
+diff --git a/nextest-runner/Cargo.toml b/nextest-runner/Cargo.toml
+index 776c9341..06196bd2 100644
+--- a/nextest-runner/Cargo.toml
++++ b/nextest-runner/Cargo.toml
+@@ -118,7 +118,7 @@ nix.workspace = true
+ #
+ # Also, usdt 0.6.0 fails to compile on x86_64-apple-darwin, so restrict it to
+ # aarch64-apple-darwin.
+-[target.'cfg(any(all(target_arch = "x86_64", any(target_os = "linux", target_os = "freebsd", target_os = "illumos")), all(target_arch = "aarch64", any(target_os = "macos", target_os = "freebsd", target_os = "illumos"))))'.dependencies]
++[target.'cfg(any(all(target_arch = "x86_64", any(target_os = "linux", target_os = "freebsd", target_os = "illumos")), all(target_arch = "aarch64", any(target_os = "freebsd", target_os = "illumos"))))'.dependencies]
+ usdt = "0.6.0"
+ 
+ [target.'cfg(windows)'.dependencies]
+diff --git a/nextest-runner/src/usdt.rs b/nextest-runner/src/usdt.rs
+index 7732eeb4..af69015b 100644
+--- a/nextest-runner/src/usdt.rs
++++ b/nextest-runner/src/usdt.rs
+@@ -28,7 +28,7 @@ use serde::Serialize;
+     ),
+     all(
+         target_arch = "aarch64",
+-        any(target_os = "macos", target_os = "freebsd", target_os = "illumos")
++        any(target_os = "freebsd", target_os = "illumos")
+     )
+ ))]
+ pub fn register_probes() -> Result<(), usdt::Error> {
+@@ -43,7 +43,7 @@ pub fn register_probes() -> Result<(), usdt::Error> {
+     ),
+     all(
+         target_arch = "aarch64",
+-        any(target_os = "macos", target_os = "freebsd", target_os = "illumos")
++        any(target_os = "freebsd", target_os = "illumos")
+     )
+ )))]
+ pub fn register_probes() -> Result<(), std::convert::Infallible> {
+@@ -57,7 +57,7 @@ pub fn register_probes() -> Result<(), std::convert::Infallible> {
+     ),
+     all(
+         target_arch = "aarch64",
+-        any(target_os = "macos", target_os = "freebsd", target_os = "illumos")
++        any(target_os = "freebsd", target_os = "illumos")
+     )
+ ))]
+ #[usdt::provider(provider = "nextest")]
+@@ -135,7 +135,7 @@ pub mod usdt_probes {
+     ),
+     all(
+         target_arch = "aarch64",
+-        any(target_os = "macos", target_os = "freebsd", target_os = "illumos")
++        any(target_os = "freebsd", target_os = "illumos")
+     )
+ ))]
+ #[macro_export]
+@@ -246,7 +246,7 @@ macro_rules! fire_usdt {
+     ),
+     all(
+         target_arch = "aarch64",
+-        any(target_os = "macos", target_os = "freebsd", target_os = "illumos")
++        any(target_os = "freebsd", target_os = "illumos")
+     )
+ )))]
+ #[macro_export]
diff --git a/pkgs/by-name/ca/cargo-nextest/package.nix b/pkgs/by-name/ca/cargo-nextest/package.nix
index 2089b3bee2c4..549f8f579250 100644
--- a/pkgs/by-name/ca/cargo-nextest/package.nix
+++ b/pkgs/by-name/ca/cargo-nextest/package.nix
@@ -1,5 +1,6 @@
 {
   lib,
+  stdenv,
   rustPlatform,
   fetchFromGitHub,
   nix-update-script,
@@ -16,6 +17,11 @@ rustPlatform.buildRustPackage rec {
     hash = "sha256-DY/FNtlNQg9Ym6PKo6UqSuWzGC3cDhbNU6MKTDxIaU4=";
   };
 
+  # FIXME: we don't support dtrace probe generation on macOS until we have a dtrace build: https://github.com/NixOS/nixpkgs/pull/392918
+  patches = lib.optionals stdenv.isDarwin [
+    ./no-dtrace-macos.patch
+  ];
+
   cargoHash = "sha256-uQH9d+9VByXe/lL4Ybz07p+iYWUhbATMBCu7mYKxOSE=";
 
   cargoBuildFlags = [