diff --git a/pkgs/development/python-modules/pyqtgraph/default.nix b/pkgs/development/python-modules/pyqtgraph/default.nix
index 23cceed4e7e0..2b7b4a1377a7 100644
--- a/pkgs/development/python-modules/pyqtgraph/default.nix
+++ b/pkgs/development/python-modules/pyqtgraph/default.nix
@@ -58,6 +58,9 @@ buildPythonPackage rec {
     # upstream doesn't consider it serious.
     # https://github.com/pyqtgraph/pyqtgraph/issues/2110
     "test_PolyLineROI"
+  ] ++ lib.optionals (stdenv.isLinux && stdenv.isAarch64) [
+    # https://github.com/pyqtgraph/pyqtgraph/issues/2645
+    "test_rescaleData"
   ];
 
   meta = with lib; {