diff --git a/pkgs/development/python-modules/essentials-openapi/default.nix b/pkgs/development/python-modules/essentials-openapi/default.nix
index cc31f97a17bb..450aedcca5b2 100644
--- a/pkgs/development/python-modules/essentials-openapi/default.nix
+++ b/pkgs/development/python-modules/essentials-openapi/default.nix
@@ -14,6 +14,7 @@
   pyyaml,
   rich,
   setuptools,
+  stdenv,
 }:
 buildPythonPackage rec {
   pname = "essentials-openapi";
@@ -59,6 +60,13 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "openapidocs" ];
 
+  disabledTestPaths = lib.optionals stdenv.hostPlatform.isDarwin [
+    # These tests start a server using a hardcoded port, and since
+    # multiple Python versions are always built simultaneously, this
+    # failure is quite likely to occur.
+    "tests/test_cli.py"
+  ];
+
   meta = {
     homepage = "https://github.com/Neoteroi/essentials-openapi";
     description = "Functions to handle OpenAPI Documentation";
diff --git a/pkgs/development/python-modules/essentials/default.nix b/pkgs/development/python-modules/essentials/default.nix
index e94a3ccf98b8..f0174bb0a081 100644
--- a/pkgs/development/python-modules/essentials/default.nix
+++ b/pkgs/development/python-modules/essentials/default.nix
@@ -3,6 +3,7 @@
   fetchFromGitHub,
   setuptools,
   pytestCheckHook,
+  stdenv,
   lib,
 }:
 buildPythonPackage rec {
@@ -21,6 +22,12 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [ pytestCheckHook ];
 
+  disabledTests = lib.optionals stdenv.hostPlatform.isDarwin [
+    # time.sleep(0.01) can be up to 0.05s on darwin
+    "test_stopwatch"
+    "test_stopwatch_with_context_manager"
+  ];
+
   pythonImportsCheck = [ "essentials" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/neoteroi-mkdocs/default.nix b/pkgs/development/python-modules/neoteroi-mkdocs/default.nix
index ad9f8ef42bd9..cc7fd7dc4542 100644
--- a/pkgs/development/python-modules/neoteroi-mkdocs/default.nix
+++ b/pkgs/development/python-modules/neoteroi-mkdocs/default.nix
@@ -12,6 +12,7 @@
   pytestCheckHook,
   rich,
   setuptools,
+  stdenv,
 }:
 buildPythonPackage rec {
   pname = "neoteroi-mkdocs";
@@ -48,6 +49,13 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "neoteroi.mkdocs" ];
 
+  disabledTestPaths = lib.optionals stdenv.hostPlatform.isDarwin [
+    # These tests start a server using a hardcoded port, and since
+    # multiple Python versions are always built simultaneously, this
+    # failure is quite likely to occur.
+    "tests/test_http.py"
+  ];
+
   meta = with lib; {
     homepage = "https://github.com/Neoteroi/mkdocs-plugins";
     description = "Plugins for MkDocs";