diff --git a/pkgs/by-name/bc/bcc/libbcc-path.patch b/pkgs/by-name/bc/bcc/libbcc-path.patch
deleted file mode 100644
index 187bb3aadd00..000000000000
--- a/pkgs/by-name/bc/bcc/libbcc-path.patch
+++ /dev/null
@@ -1,11 +0,0 @@
---- source.org/src/python/bcc/libbcc.py	2018-05-13 08:35:06.850522883 +0100
-+++ source/src/python/bcc/libbcc.py	2018-05-13 08:36:24.602733151 +0100
-@@ -14,7 +14,7 @@
- 
- import ctypes as ct
- 
--lib = ct.CDLL("libbcc.so.0", use_errno=True)
-+lib = ct.CDLL("@out@/lib/libbcc.so.0", use_errno=True)
- 
- # keep in sync with bpf_common.h
- lib.bpf_module_create_b.restype = ct.c_void_p
diff --git a/pkgs/by-name/bc/bcc/package.nix b/pkgs/by-name/bc/bcc/package.nix
index c45d4b854b7e..27cd51936203 100644
--- a/pkgs/by-name/bc/bcc/package.nix
+++ b/pkgs/by-name/bc/bcc/package.nix
@@ -16,15 +16,14 @@
   nixosTests,
   python3Packages,
   readline,
-  stdenv,
+  replaceVars,
   zip,
 }:
 
 python3Packages.buildPythonApplication rec {
   pname = "bcc";
   version = "0.35.0";
-
-  disabled = !stdenv.hostPlatform.isLinux;
+  pyproject = false;
 
   src = fetchFromGitHub {
     owner = "iovisor";
@@ -32,12 +31,36 @@ python3Packages.buildPythonApplication rec {
     tag = "v${version}";
     hash = "sha256-eP/VEq7cPALi2oDKAZFQGQ3NExdmcBKyi6ddRZiYmbI=";
   };
-  format = "other";
 
-  buildInputs = with llvmPackages; [
-    llvm
-    llvm.dev
-    libclang
+  patches = [
+    # This is needed until we fix
+    # https://github.com/NixOS/nixpkgs/issues/40427
+    ./fix-deadlock-detector-import.patch
+    # Quick & dirty fix for bashreadline
+    # https://github.com/NixOS/nixpkgs/issues/328743
+    ./bashreadline.py-remove-dependency-on-elftools.patch
+
+    (replaceVars ./absolute-ausyscall.patch {
+      ausyscall = lib.getExe' audit "ausyscall";
+    })
+  ];
+
+  build-system = [ python3Packages.setuptools ];
+
+  dependencies = [ python3Packages.netaddr ];
+
+  nativeBuildInputs = [
+    bison
+    cmake
+    flex
+    llvmPackages.llvm
+    makeWrapper
+    zip
+  ];
+
+  buildInputs = [
+    llvmPackages.llvm
+    llvmPackages.libclang
     elfutils
     luajit
     netperf
@@ -47,45 +70,18 @@ python3Packages.buildPythonApplication rec {
     libbpf
   ];
 
-  patches = [
-    # This is needed until we fix
-    # https://github.com/NixOS/nixpkgs/issues/40427
-    ./fix-deadlock-detector-import.patch
-    # Quick & dirty fix for bashreadline
-    # https://github.com/NixOS/nixpkgs/issues/328743
-    ./bashreadline.py-remove-dependency-on-elftools.patch
-  ];
-
-  propagatedBuildInputs = [ python3Packages.netaddr ];
-  nativeBuildInputs = [
-    bison
-    cmake
-    flex
-    llvmPackages.llvm.dev
-    makeWrapper
-    python3Packages.setuptools
-    zip
-  ];
-
   cmakeFlags = [
-    "-DBCC_KERNEL_MODULES_DIR=/run/booted-system/kernel-modules/lib/modules"
-    "-DREVISION=${version}"
-    "-DENABLE_USDT=ON"
-    "-DENABLE_CPP_API=ON"
-    "-DCMAKE_USE_LIBBPF_PACKAGE=ON"
-    "-DENABLE_LIBDEBUGINFOD=OFF"
+    (lib.cmakeFeature "BCC_KERNEL_MODULES_DIR" "/run/booted-system/kernel-modules/lib/modules")
+    (lib.cmakeFeature "REVISION" version)
+    (lib.cmakeBool "ENABLE_USDT" true)
+    (lib.cmakeBool "ENABLE_CPP_API" true)
+    (lib.cmakeBool "CMAKE_USE_LIBBPF_PACKAGE" true)
+    (lib.cmakeBool "ENABLE_LIBDEBUGINFOD" false)
   ];
 
-  # to replace this executable path:
-  # https://github.com/iovisor/bcc/blob/master/src/python/bcc/syscall.py#L384
-  ausyscall = "${audit}/bin/ausyscall";
-
   postPatch = ''
-    substituteAll ${./libbcc-path.patch} ./libbcc-path.patch
-    patch -p1 < libbcc-path.patch
-
-    substituteAll ${./absolute-ausyscall.patch} ./absolute-ausyscall.patch
-    patch -p1 < absolute-ausyscall.patch
+    substituteInPlace src/python/bcc/libbcc.py \
+      --replace-fail "libbcc.so.0" "$out/lib/libbcc.so.0"
 
     # https://github.com/iovisor/bcc/issues/3996
     substituteInPlace src/cc/libbcc.pc.in \
@@ -95,10 +91,6 @@ python3Packages.buildPythonApplication rec {
       --replace-fail '/bin/bash' '${readline}/lib/libreadline.so'
   '';
 
-  preInstall = ''
-    # required for setuptool during install
-    export PYTHONPATH=$out/${python3Packages.python.sitePackages}:$PYTHONPATH
-  '';
   postInstall = ''
     mkdir -p $out/bin $out/share
     rm -r $out/share/bcc/tools/old