diff --git a/pkgs/development/python-modules/hdf5plugin/default.nix b/pkgs/development/python-modules/hdf5plugin/default.nix
new file mode 100644
index 000000000000..0716c65f2fb4
--- /dev/null
+++ b/pkgs/development/python-modules/hdf5plugin/default.nix
@@ -0,0 +1,45 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, h5py
+}:
+
+buildPythonPackage rec {
+  pname = "hdf5plugin";
+  version = "4.1.0";
+  format = "setuptools";
+
+  src = fetchFromGitHub {
+    owner = "silx-kit";
+    repo = "hdf5plugin";
+    rev = "refs/tags/v${version}";
+    hash = "sha256-fFR5t8jHOQc6eDNDhDcntibaveGAmI+j/dVte1tdcyk=";
+  };
+
+  propagatedBuildInputs = [
+    h5py
+  ];
+
+  checkPhase = ''
+    python test/test.py
+  '';
+  pythonImportsCheck = [
+    "hdf5plugin"
+  ];
+
+  preBuild = ''
+    mkdir src/hdf5plugin/plugins
+  '';
+
+  meta = with lib; {
+    description = "Additional compression filters for h5py";
+    longDescription = ''
+      hdf5plugin provides HDF5 compression filters and makes them usable from h5py.
+      Supported encodings: Blosc, Blosc2, BitShuffle, BZip2, FciDecomp, LZ4, SZ, SZ3, Zfp, ZStd
+    '';
+    homepage = "http://www.silx.org/doc/hdf5plugin/latest/";
+    license = licenses.mit;
+    maintainers = with maintainers; [ bhipple ];
+  };
+
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index dc5d0f42c90b..48b188ddf43e 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4189,6 +4189,8 @@ self: super: with self; {
 
   hdate = callPackage ../development/python-modules/hdate { };
 
+  hdf5plugin = callPackage ../development/python-modules/hdf5plugin { };
+
   ha-ffmpeg = callPackage ../development/python-modules/ha-ffmpeg { };
 
   ha-philipsjs = callPackage ../development/python-modules/ha-philipsjs{ };