diff --git a/pkgs/development/python-modules/astropy/default.nix b/pkgs/development/python-modules/astropy/default.nix
index be3519491eae..10076ca6d9ae 100644
--- a/pkgs/development/python-modules/astropy/default.nix
+++ b/pkgs/development/python-modules/astropy/default.nix
@@ -12,6 +12,7 @@
 , wheel
 # testing
 , pytestCheckHook
+, stdenv
 , pytest-xdist
 , pytest-astropy
 
@@ -82,6 +83,9 @@ buildPythonPackage rec {
     # More flaky tests, see: https://github.com/NixOS/nixpkgs/issues/294392
     "test_sidereal_lon_independent"
     "test_timedelta_full_precision_arithmetic"
+    "test_datetime_to_timedelta"
+  ] ++ lib.optionals stdenv.isDarwin [
+    "test_sidereal_lat_independent"
   ];
 
   meta = {