diff --git a/pkgs/development/python-modules/quaternion/default.nix b/pkgs/development/python-modules/quaternion/default.nix
new file mode 100644
index 000000000000..ad53a085d327
--- /dev/null
+++ b/pkgs/development/python-modules/quaternion/default.nix
@@ -0,0 +1,33 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, oldest-supported-numpy
+, scipy
+, numba
+}:
+
+buildPythonPackage rec {
+  pname = "quaternion";
+  version = "2022.4.3";
+  format = "pyproject";
+
+  src = fetchFromGitHub {
+    owner = "moble";
+    repo = pname;
+    rev = "refs/tags/v${version}";
+    hash = "sha256-iLjVQ6eGwpLQXi8Sr5ShJdXMqYNclGEuq/oxR4ExDLA=";
+  };
+
+  propagatedBuildInputs = [
+    oldest-supported-numpy
+    numba
+    scipy
+  ];
+
+  meta = with lib; {
+    description = "A package add built-in support for quaternions to numpy";
+    homepage = "https://github.com/moble/quaternion";
+    license = licenses.mit;
+    maintainers = [ maintainers.ocfox ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 6bc33c124921..37350b1ec2e2 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -10941,6 +10941,8 @@ self: super: with self; {
 
   quart-cors = callPackage ../development/python-modules/quart-cors { };
 
+  quaternion = callPackage ../development/python-modules/quaternion { };
+
   qudida = callPackage ../development/python-modules/qudida { };
 
   querystring_parser = callPackage ../development/python-modules/querystring-parser { };