diff --git a/pkgs/by-name/ea/easyeda2kicad/package.nix b/pkgs/by-name/ea/easyeda2kicad/package.nix
index db16be875449..01aa63f5fc89 100644
--- a/pkgs/by-name/ea/easyeda2kicad/package.nix
+++ b/pkgs/by-name/ea/easyeda2kicad/package.nix
@@ -7,15 +7,18 @@
 python3Packages.buildPythonPackage rec {
   pname = "easyeda2kicad";
   version = "0.8.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-p4G+bRB29uBohqQpI3PrkwyZId5McJ1t2Ru26hBPSks=";
   };
 
-  dependencies = with python3Packages; [
+  build-system = with python3Packages; [
     setuptools
+  ];
+
+  dependencies = with python3Packages; [
     pydantic
     requests
   ];
diff --git a/pkgs/by-name/en/endgame-singularity/package.nix b/pkgs/by-name/en/endgame-singularity/package.nix
index 4736be067c4d..21fd5c4faff5 100644
--- a/pkgs/by-name/en/endgame-singularity/package.nix
+++ b/pkgs/by-name/en/endgame-singularity/package.nix
@@ -25,14 +25,19 @@ let
 in
 
 python3.pkgs.buildPythonApplication {
-  format = "setuptools";
+  format = "pyproject";
   inherit pname version;
 
   srcs = [ main_src ] ++ lib.optional enableDefaultMusicPack music_src;
   sourceRoot = main_src.name;
 
   nativeBuildInputs = [ unzip ]; # The music is zipped
-  propagatedBuildInputs = with python3.pkgs; [
+
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     pygame
     numpy
     polib
diff --git a/pkgs/by-name/ep/epr/package.nix b/pkgs/by-name/ep/epr/package.nix
index 4169920893a2..520237e7e018 100644
--- a/pkgs/by-name/ep/epr/package.nix
+++ b/pkgs/by-name/ep/epr/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "epr";
   version = "2.4.13";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "wustho";
@@ -16,6 +16,10 @@ python3Packages.buildPythonApplication rec {
     sha256 = "sha256-1qsqYlqGlCRhl7HINrcTDt5bGlb7g5PmaERylT+UvEg=";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   meta = with lib; {
     description = "CLI Epub Reader";
     mainProgram = "epr";
diff --git a/pkgs/by-name/er/errbot/package.nix b/pkgs/by-name/er/errbot/package.nix
index 51f8e9916b5d..071643f5ab1c 100644
--- a/pkgs/by-name/er/errbot/package.nix
+++ b/pkgs/by-name/er/errbot/package.nix
@@ -8,7 +8,7 @@ python3.pkgs.buildPythonApplication rec {
   pname = "errbot";
   version = "6.2.0";
 
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "errbotio";
@@ -17,9 +17,13 @@ python3.pkgs.buildPythonApplication rec {
     hash = "sha256-UdqzBrlcb9NkuVo8ChADJmaKevadoGLyZUrckStb5ko=";
   };
 
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
   pythonRelaxDeps = true;
 
-  propagatedBuildInputs = with python3.pkgs; [
+  dependencies = with python3.pkgs; [
     ansi
     colorlog
     daemonize
diff --git a/pkgs/by-name/es/escrotum/package.nix b/pkgs/by-name/es/escrotum/package.nix
index 306fe110ee5a..87a42a0f18df 100644
--- a/pkgs/by-name/es/escrotum/package.nix
+++ b/pkgs/by-name/es/escrotum/package.nix
@@ -9,11 +9,10 @@
   wrapGAppsHook3,
 }:
 
-with python3Packages;
-buildPythonApplication {
+python3Packages.buildPythonApplication {
   pname = "escrotum";
   version = "unstable-2020-12-07";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "Roger";
@@ -32,7 +31,11 @@ buildPythonApplication {
     wrapGAppsHook3
   ];
 
-  propagatedBuildInputs = [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     pygobject3
     xcffib
     pycairo
diff --git a/pkgs/by-name/et/etesync-dav/package.nix b/pkgs/by-name/et/etesync-dav/package.nix
index 6c9edf44299c..8f88134a4c11 100644
--- a/pkgs/by-name/et/etesync-dav/package.nix
+++ b/pkgs/by-name/et/etesync-dav/package.nix
@@ -9,7 +9,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "etesync-dav";
   version = "0.34.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "etesync";
@@ -18,6 +18,10 @@ python3Packages.buildPythonApplication rec {
     hash = "sha256-+rNqyksOmDUh0OuvgEDWv6tuZQkn1gizz35Ptr6izos=";
   };
 
+  build-system = with python3Packages; [ setuptools ];
+
+  pythonRelaxDeps = [ "radicale" ];
+
   dependencies = with python3Packages; [
     appdirs
     etebase
@@ -25,10 +29,8 @@ python3Packages.buildPythonApplication rec {
     flask
     flask-wtf
     msgpack
-    setuptools
     (python3Packages.toPythonModule (radicale.override { python3 = python; }))
     requests
-    types-setuptools
     requests.optional-dependencies.socks
   ];
 
diff --git a/pkgs/by-name/ev/evdevremapkeys/package.nix b/pkgs/by-name/ev/evdevremapkeys/package.nix
index f1cde58569b6..2a9e1e44d200 100644
--- a/pkgs/by-name/ev/evdevremapkeys/package.nix
+++ b/pkgs/by-name/ev/evdevremapkeys/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonPackage {
   pname = "evdevremapkeys";
   version = "unstable-2021-05-04";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "philipl";
@@ -16,7 +16,11 @@ python3Packages.buildPythonPackage {
     sha256 = "sha256-FwRbo0RTiiV2AB7z6XOalMnwMbj15jM4Dxs41TsIOQI=";
   };
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     pyyaml
     pyxdg
     python-daemon
diff --git a/pkgs/by-name/fa/fastcov/package.nix b/pkgs/by-name/fa/fastcov/package.nix
index 4e3439da9ae8..95505a638c5e 100644
--- a/pkgs/by-name/fa/fastcov/package.nix
+++ b/pkgs/by-name/fa/fastcov/package.nix
@@ -10,7 +10,7 @@
 python3Packages.buildPythonPackage rec {
   pname = "fastcov";
   version = "1.16";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "RPGillespie6";
diff --git a/pkgs/by-name/ff/ffmpeg-normalize/package.nix b/pkgs/by-name/ff/ffmpeg-normalize/package.nix
index 0f7810b22a53..4739db508f91 100644
--- a/pkgs/by-name/ff/ffmpeg-normalize/package.nix
+++ b/pkgs/by-name/ff/ffmpeg-normalize/package.nix
@@ -8,7 +8,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "ffmpeg-normalize";
   version = "1.31.3";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit version;
@@ -16,6 +16,10 @@ python3Packages.buildPythonApplication rec {
     hash = "sha256-sewDSBUX6gCZSIHeRtpx5fQGtOKN8OWZKrtCF2bgI9Y=";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   dependencies =
     with python3Packages;
     [
diff --git a/pkgs/by-name/fi/fileinfo/package.nix b/pkgs/by-name/fi/fileinfo/package.nix
index 41bea4d85656..3974e5e526cc 100644
--- a/pkgs/by-name/fi/fileinfo/package.nix
+++ b/pkgs/by-name/fi/fileinfo/package.nix
@@ -6,7 +6,8 @@
 python3Packages.buildPythonApplication {
   pname = "fileinfo";
   version = "unstable-2022-09-16";
-  format = "setuptools";
+  format = "pyproject";
+
   src = fetchFromGitHub {
     owner = "sdushantha";
     repo = "fileinfo";
@@ -14,7 +15,9 @@ python3Packages.buildPythonApplication {
     hash = "sha256-tEmCsR3LmTxeDZAbMvbIwqp/6uaGNUhgGlm18gdsnOw=";
   };
 
-  propagatedBuildInputs = with python3Packages; [ requests ];
+  build-system = with python3Packages; [ setuptools ];
+
+  dependencies = with python3Packages; [ requests ];
 
   meta = with lib; {
     homepage = "https://github.com/sdushantha/fileinfo";
diff --git a/pkgs/by-name/fl/flac2all/package.nix b/pkgs/by-name/fl/flac2all/package.nix
index 5e8783941393..93ce231f9c54 100644
--- a/pkgs/by-name/fl/flac2all/package.nix
+++ b/pkgs/by-name/fl/flac2all/package.nix
@@ -12,7 +12,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "flac2all";
   version = "5.1";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
@@ -24,7 +24,11 @@ python3Packages.buildPythonApplication rec {
     echo ${version} > ./flac2all_pkg/version
   '';
 
-  propagatedBuildInputs = [
+  build-system = [
+    python3Packages.setuptools
+  ];
+
+  dependencies = [
     python3Packages.pyzmq
   ];
 
diff --git a/pkgs/by-name/fl/flattenReferencesGraph/package.nix b/pkgs/by-name/fl/flattenReferencesGraph/package.nix
index c5b8fbafcd68..952b71e90551 100644
--- a/pkgs/by-name/fl/flattenReferencesGraph/package.nix
+++ b/pkgs/by-name/fl/flattenReferencesGraph/package.nix
@@ -10,13 +10,17 @@ let
 in
 pythonPackages.buildPythonApplication {
   version = "0.1.0";
-  format = "setuptools";
+  format = "pyproject";
   pname = "flatten-references-graph";
 
   # Note: this uses only ./src/.gitignore
   src = nix-gitignore.gitignoreSource [ ] ./src;
 
-  propagatedBuildInputs = with pythonPackages; [
+  build-system = with pythonPackages; [
+    setuptools
+  ];
+
+  dependencies = with pythonPackages; [
     igraph
     toolz
   ];
diff --git a/pkgs/by-name/fl/flawfinder/package.nix b/pkgs/by-name/fl/flawfinder/package.nix
index 41d235b269bd..bdb99f4e6ffb 100644
--- a/pkgs/by-name/fl/flawfinder/package.nix
+++ b/pkgs/by-name/fl/flawfinder/package.nix
@@ -7,13 +7,17 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "flawfinder";
   version = "2.0.19";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchurl {
     url = "https://dwheeler.com/flawfinder/flawfinder-${version}.tar.gz";
     sha256 = "sha256-/lUJgdNwq/oKKWcTRswLA4Ipqb2QsjnqsPAfEiEt9hg=";
   };
 
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
   # Project is using a combination of bash/Python for the tests
   doCheck = false;
 
diff --git a/pkgs/by-name/fl/flent/package.nix b/pkgs/by-name/fl/flent/package.nix
index 31c9f6196b3c..c8663c675f1e 100644
--- a/pkgs/by-name/fl/flent/package.nix
+++ b/pkgs/by-name/fl/flent/package.nix
@@ -9,14 +9,17 @@
 python3Packages.buildPythonApplication rec {
   pname = "flent";
   version = "2.2.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-BPwh3oWIY1YEI+ecgi9AUiX4Ka/Y5dYikwmfvvNB+eg=";
   };
 
-  build-system = [ python3Packages.sphinx ];
+  build-system = with python3Packages; [
+    setuptools
+    sphinx
+  ];
 
   nativeBuildInputs = [ qt5.wrapQtAppsHook ];
 
diff --git a/pkgs/by-name/fl/flootty/package.nix b/pkgs/by-name/fl/flootty/package.nix
index dc3c7619261a..ac43300e145d 100644
--- a/pkgs/by-name/fl/flootty/package.nix
+++ b/pkgs/by-name/fl/flootty/package.nix
@@ -7,13 +7,17 @@
 python3Packages.buildPythonApplication rec {
   pname = "Flootty";
   version = "3.2.2";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     sha256 = "0gfl143ly81pmmrcml91yr0ypvwrs5q4s1sfdc0l2qkqpy233ih7";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   meta = with lib; {
     description = "Collaborative terminal. In practice, it's similar to a shared screen or tmux session";
     mainProgram = "flootty";
diff --git a/pkgs/by-name/fl/fluxboxlauncher/package.nix b/pkgs/by-name/fl/fluxboxlauncher/package.nix
index 1465b094e667..9c1bedd38edd 100644
--- a/pkgs/by-name/fl/fluxboxlauncher/package.nix
+++ b/pkgs/by-name/fl/fluxboxlauncher/package.nix
@@ -16,7 +16,7 @@
 python3.pkgs.buildPythonApplication {
   pname = "fluxboxlauncher";
   version = "0.2.1";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "mothsart";
@@ -46,7 +46,11 @@ python3.pkgs.buildPythonApplication {
     "--set CHARSET en_us.UTF-8"
   ];
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     pygobject3
   ];
 
diff --git a/pkgs/by-name/fp/fprettify/package.nix b/pkgs/by-name/fp/fprettify/package.nix
index 0433d9294f39..f5b647e3df0a 100644
--- a/pkgs/by-name/fp/fprettify/package.nix
+++ b/pkgs/by-name/fp/fprettify/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "fprettify";
   version = "0.3.7";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "pseewald";
@@ -20,7 +20,11 @@ python3Packages.buildPythonApplication rec {
     patchShebangs fprettify.py
   '';
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     configargparse
   ];
 
diff --git a/pkgs/by-name/fr/frida-tools/package.nix b/pkgs/by-name/fr/frida-tools/package.nix
index 5ef11d72dde6..c55458108dd0 100644
--- a/pkgs/by-name/fr/frida-tools/package.nix
+++ b/pkgs/by-name/fr/frida-tools/package.nix
@@ -7,14 +7,23 @@
 python3Packages.buildPythonApplication rec {
   pname = "frida-tools";
   version = "14.4.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-ACiznCkOZvnPUSB+Xcs4IZfbPGyknr193gLok0FrzqA=";
   };
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  pythonRelaxDeps = [
+    "frida"
+    "websockets"
+  ];
+
+  dependencies = with python3Packages; [
     pygments
     prompt-toolkit
     colorama
diff --git a/pkgs/by-name/ge/genxword/package.nix b/pkgs/by-name/ge/genxword/package.nix
index c16affd8aa22..a65408897ee8 100644
--- a/pkgs/by-name/ge/genxword/package.nix
+++ b/pkgs/by-name/ge/genxword/package.nix
@@ -12,7 +12,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "genxword";
   version = "2.1.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "riverrun";
@@ -32,7 +32,11 @@ python3.pkgs.buildPythonApplication rec {
     gtksourceview3
   ];
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     pycairo
     pygobject3
   ];
diff --git a/pkgs/by-name/ge/gersemi/package.nix b/pkgs/by-name/ge/gersemi/package.nix
index e17fe104e49e..e51346216df8 100644
--- a/pkgs/by-name/ge/gersemi/package.nix
+++ b/pkgs/by-name/ge/gersemi/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "gersemi";
   version = "0.19.3";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "BlankSpruce";
@@ -16,7 +16,11 @@ python3Packages.buildPythonApplication rec {
     hash = "sha256-CVb6ibO5+Tp0o+nB+bo9G9OKyB4L05wN1QiB9J4bOqY=";
   };
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     appdirs
     colorama
     lark
diff --git a/pkgs/by-name/gh/gh2md/package.nix b/pkgs/by-name/gh/gh2md/package.nix
index 648a47731d08..8683047dffdc 100644
--- a/pkgs/by-name/gh/gh2md/package.nix
+++ b/pkgs/by-name/gh/gh2md/package.nix
@@ -7,14 +7,18 @@
 python3Packages.buildPythonApplication rec {
   pname = "gh2md";
   version = "2.3.1";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-B7IB1TWfZ0StH2zo/tXfDAaPlgLvr4ciIv7B8EQyp8w=";
   };
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     six
     requests
     python-dateutil
diff --git a/pkgs/by-name/gh/ghdorker/package.nix b/pkgs/by-name/gh/ghdorker/package.nix
index be12f9e18ed6..4d0a079da2af 100644
--- a/pkgs/by-name/gh/ghdorker/package.nix
+++ b/pkgs/by-name/gh/ghdorker/package.nix
@@ -7,14 +7,18 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "ghdorker";
   version = "0.3.2";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-wF4QoXxH55SpdYgKLHf4sCwUk1rkCpSdnIX5FvFi/BU=";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     ghapi
     glom
     python-dotenv
diff --git a/pkgs/by-name/gh/ghost/package.nix b/pkgs/by-name/gh/ghost/package.nix
index 3a771183511e..10cda94d8eb1 100644
--- a/pkgs/by-name/gh/ghost/package.nix
+++ b/pkgs/by-name/gh/ghost/package.nix
@@ -7,7 +7,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "ghost";
   version = "8.0.0";
-  format = "setuptools";
+  format = "pyproject";
 
   disabled = python3.pythonOlder "3.7";
 
@@ -18,7 +18,11 @@ python3.pkgs.buildPythonApplication rec {
     sha256 = "13p3inw7v55na8438awr692v9vb7zgf5ggxpha9r3m8vfm3sb4iz";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     adb-shell
   ];
 
diff --git a/pkgs/by-name/gi/git-branchstack/package.nix b/pkgs/by-name/gi/git-branchstack/package.nix
index 5df2b45409cd..db3aff164061 100644
--- a/pkgs/by-name/gi/git-branchstack/package.nix
+++ b/pkgs/by-name/gi/git-branchstack/package.nix
@@ -8,7 +8,7 @@ let
   self = python3Packages.buildPythonApplication {
     pname = "git-branchstack";
     version = "0.2.0";
-    format = "setuptools";
+    format = "pyproject";
 
     src = fetchPypi {
       pname = "git-branchstack";
@@ -16,6 +16,10 @@ let
       hash = "sha256-gja93LOcVCQ6l+Cygvsm+3uomvxtvUl6t23GIb/tKyQ=";
     };
 
+    build-system = with python3Packages; [
+      setuptools
+    ];
+
     dependencies = with python3Packages; [
       git-revise
     ];
diff --git a/pkgs/by-name/gi/git-crecord/package.nix b/pkgs/by-name/gi/git-crecord/package.nix
index 8ca27f22df10..230ebe72c5f0 100644
--- a/pkgs/by-name/gi/git-crecord/package.nix
+++ b/pkgs/by-name/gi/git-crecord/package.nix
@@ -7,7 +7,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "git-crecord";
   version = "20230226.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "andrewshadura";
@@ -16,7 +16,9 @@ python3.pkgs.buildPythonApplication rec {
     sha256 = "sha256-zsrMAD9EU+TvkWfWl9x6WbMXuw7YEz50LxQzSFVkKdQ=";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [ docutils ];
+  build-system = with python3.pkgs; [ setuptools ];
+
+  dependencies = with python3.pkgs; [ docutils ];
 
   # has no tests
   doCheck = false;
diff --git a/pkgs/by-name/gi/git-machete/package.nix b/pkgs/by-name/gi/git-machete/package.nix
index e48473843ddc..ef60f119c4e5 100644
--- a/pkgs/by-name/gi/git-machete/package.nix
+++ b/pkgs/by-name/gi/git-machete/package.nix
@@ -10,7 +10,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "git-machete";
   version = "3.36.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "virtuslab";
@@ -19,6 +19,8 @@ python3.pkgs.buildPythonApplication rec {
     hash = "sha256-iSuOiQC+dKqcDCS4nTPMrNFpo3ipPUQhfoofM11UInI=";
   };
 
+  build-system = with python3.pkgs; [ setuptools ];
+
   nativeBuildInputs = [ installShellFiles ];
 
   nativeCheckInputs =
diff --git a/pkgs/by-name/gi/git-privacy/package.nix b/pkgs/by-name/gi/git-privacy/package.nix
index b898beded66e..0a02f7c1ba96 100644
--- a/pkgs/by-name/gi/git-privacy/package.nix
+++ b/pkgs/by-name/gi/git-privacy/package.nix
@@ -8,7 +8,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "git-privacy";
   version = "2.3.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "EMPRI-DEVOPS";
@@ -17,7 +17,11 @@ python3.pkgs.buildPythonApplication rec {
     hash = "sha256-b2RkRL8/mZwqc3xCs+oltzualhQtp/7F9POlLlT3UUU=";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     click
     git-filter-repo
     gitpython
diff --git a/pkgs/by-name/gi/git-remote-codecommit/package.nix b/pkgs/by-name/gi/git-remote-codecommit/package.nix
index 038475eb87d6..6e929ec79877 100644
--- a/pkgs/by-name/gi/git-remote-codecommit/package.nix
+++ b/pkgs/by-name/gi/git-remote-codecommit/package.nix
@@ -8,7 +8,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "git-remote-codecommit";
   version = "1.17";
-  format = "setuptools";
+  format = "pyproject";
   disabled = !python3Packages.isPy3k;
 
   # The check dependency awscli has some overrides
@@ -25,6 +25,8 @@ python3Packages.buildPythonApplication rec {
     hash = "sha256-8heI0Oyfhuvshedw+Eqmwd+e9cOHdDt4O588dplqv/k=";
   };
 
+  build-system = with python3Packages; [ setuptools ];
+
   dependencies = with python3Packages; [ botocore ];
 
   nativeCheckInputs =
diff --git a/pkgs/by-name/gi/git-remote-hg/package.nix b/pkgs/by-name/gi/git-remote-hg/package.nix
index 2c480a162d7c..aecaaa05b842 100644
--- a/pkgs/by-name/gi/git-remote-hg/package.nix
+++ b/pkgs/by-name/gi/git-remote-hg/package.nix
@@ -13,7 +13,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "git-remote-hg";
   version = "1.0.4";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "mnauw";
@@ -31,6 +31,8 @@ python3Packages.buildPythonApplication rec {
     libxml2
   ];
 
+  build-system = with python3Packages; [ setuptools ];
+
   dependencies = with python3Packages; [ mercurial ];
 
   postInstall = ''
diff --git a/pkgs/by-name/gi/gitless/package.nix b/pkgs/by-name/gi/gitless/package.nix
index a2dc1a72a35e..deb6505c025a 100644
--- a/pkgs/by-name/gi/gitless/package.nix
+++ b/pkgs/by-name/gi/gitless/package.nix
@@ -7,7 +7,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "gitless";
   version = "0.9.17";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "goldstar611";
@@ -16,7 +16,11 @@ python3.pkgs.buildPythonApplication rec {
     hash = "sha256-XDB1i2b1reMCM6i1uK3IzTnsoLXO7jldYtNlYUo1AoQ=";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     pygit2
     argcomplete
   ];
diff --git a/pkgs/by-name/gl/gladtex/package.nix b/pkgs/by-name/gl/gladtex/package.nix
index e1c778ee3990..528a428978a2 100644
--- a/pkgs/by-name/gl/gladtex/package.nix
+++ b/pkgs/by-name/gl/gladtex/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonPackage {
   pname = "gladtex";
   version = "unstable-2023-01-22";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "humenda";
@@ -16,6 +16,10 @@ python3Packages.buildPythonPackage {
     sha256 = "sha256-B5sNEmLO4iIJRDgcPhr9LFKV77dPJws8ITNz4R+FE08=";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   meta = with lib; {
     description = "Embed LaTeX formulas into HTML documents as SVG images";
     mainProgram = "gladtex";
diff --git a/pkgs/by-name/go/gomp/package.nix b/pkgs/by-name/go/gomp/package.nix
index 6a91b600e35b..88e296b4f9f6 100644
--- a/pkgs/by-name/go/gomp/package.nix
+++ b/pkgs/by-name/go/gomp/package.nix
@@ -7,13 +7,17 @@
 python3Packages.buildPythonApplication rec {
   pname = "gomp";
   version = "1.1.1";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     sha256 = "sha256-Ixq9jtV56FKbh68jqmRd3lwpbMG00GcOUIpjzJhnSp0=";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   doCheck = false; # tests require interactive terminal
 
   meta = with lib; {
diff --git a/pkgs/by-name/go/gorilla-cli/package.nix b/pkgs/by-name/go/gorilla-cli/package.nix
index 6081e3c16023..a98bb8b3a52f 100644
--- a/pkgs/by-name/go/gorilla-cli/package.nix
+++ b/pkgs/by-name/go/gorilla-cli/package.nix
@@ -8,7 +8,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "gorilla-cli";
   version = "0.0.9";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "gorilla-llm";
@@ -19,7 +19,11 @@ python3.pkgs.buildPythonApplication rec {
 
   disabled = python3.pythonOlder "3.6";
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     requests
     halo
     prompt-toolkit
diff --git a/pkgs/by-name/gr/grabserial/package.nix b/pkgs/by-name/gr/grabserial/package.nix
index d95ca513b5ec..e51150729b5d 100644
--- a/pkgs/by-name/gr/grabserial/package.nix
+++ b/pkgs/by-name/gr/grabserial/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "grabserial";
   version = "2.1.8";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "tbird20d";
@@ -16,6 +16,8 @@ python3Packages.buildPythonApplication rec {
     hash = "sha256-XHI5r4OkJUtMuH83jKvNttEpKpqARjxj9SDLzhSPxSc=";
   };
 
+  build-system = [ python3Packages.setuptools ];
+
   dependencies = [ python3Packages.pyserial ];
 
   # no usable tests
diff --git a/pkgs/by-name/gr/graph-cli/package.nix b/pkgs/by-name/gr/graph-cli/package.nix
index b819722d5fac..53ef6d90fed4 100644
--- a/pkgs/by-name/gr/graph-cli/package.nix
+++ b/pkgs/by-name/gr/graph-cli/package.nix
@@ -8,7 +8,7 @@
 python3Packages.buildPythonApplication rec {
   pname = "graph-cli";
   version = "0.1.19";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit version;
@@ -24,7 +24,11 @@ python3Packages.buildPythonApplication rec {
     makeWrapperArgs+=("''${qtWrapperArgs[@]}")
   '';
 
-  propagatedBuildInputs = with python3Packages; [
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
+  dependencies = with python3Packages; [
     numpy
     pandas
     (matplotlib.override { enableQt = true; })
diff --git a/pkgs/by-name/gr/graphqlmap/package.nix b/pkgs/by-name/gr/graphqlmap/package.nix
index eb81d9457fbc..4208d54fa3fa 100644
--- a/pkgs/by-name/gr/graphqlmap/package.nix
+++ b/pkgs/by-name/gr/graphqlmap/package.nix
@@ -7,7 +7,7 @@
 python3.pkgs.buildPythonApplication {
   pname = "graphqlmap";
   version = "unstable-2022-01-17";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "swisskyrepo";
@@ -16,7 +16,11 @@ python3.pkgs.buildPythonApplication {
     hash = "sha256-lGnhNwtDc8KoPlwJ1p2FYq0NQ8PhSR3HgtluU7uxa/c=";
   };
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     requests
   ];
 
diff --git a/pkgs/by-name/gs/gshogi/package.nix b/pkgs/by-name/gs/gshogi/package.nix
index c015b3c92c05..39ba5269110a 100644
--- a/pkgs/by-name/gs/gshogi/package.nix
+++ b/pkgs/by-name/gs/gshogi/package.nix
@@ -10,7 +10,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "gshogi";
   version = "0.5.1";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "johncheetham";
@@ -30,7 +30,11 @@ python3.pkgs.buildPythonApplication rec {
     gobject-introspection
   ];
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     pygobject3
     pycairo
   ];
diff --git a/pkgs/by-name/ha/hashid/package.nix b/pkgs/by-name/ha/hashid/package.nix
index 15e015dd6589..7aa8ff7e69f6 100644
--- a/pkgs/by-name/ha/hashid/package.nix
+++ b/pkgs/by-name/ha/hashid/package.nix
@@ -7,7 +7,7 @@
 python3Packages.buildPythonApplication {
   pname = "hashid";
   version = "3.1.4-unstable-2015-03-17";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "psypanda";
@@ -16,6 +16,10 @@ python3Packages.buildPythonApplication {
     hash = "sha256-R2r/UYRcHbpfOz/XqtSUIpd826eT1Erfo7frAiArT34=";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   meta = with lib; {
     description = "Software to identify the different types of hashes";
     homepage = "https://github.com/psypanda/hashID";
diff --git a/pkgs/by-name/he/heisenbridge/package.nix b/pkgs/by-name/he/heisenbridge/package.nix
index 0015cc014bab..18c80d69b3f6 100644
--- a/pkgs/by-name/he/heisenbridge/package.nix
+++ b/pkgs/by-name/he/heisenbridge/package.nix
@@ -8,7 +8,7 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "heisenbridge";
   version = "1.15.3";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "hifi";
@@ -21,7 +21,15 @@ python3.pkgs.buildPythonApplication rec {
     echo "${version}" > heisenbridge/version.txt
   '';
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  pythonRelaxDeps = [
+    "irc"
+  ];
+
+  dependencies = with python3.pkgs; [
     irc
     ruamel-yaml
     mautrix
diff --git a/pkgs/by-name/ho/holehe/package.nix b/pkgs/by-name/ho/holehe/package.nix
index 7ca26d2d10af..6b706c77bdb6 100644
--- a/pkgs/by-name/ho/holehe/package.nix
+++ b/pkgs/by-name/ho/holehe/package.nix
@@ -7,7 +7,7 @@
 python3.pkgs.buildPythonApplication {
   pname = "holehe";
   version = "unstable-2023-05-18";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "megadose";
@@ -19,10 +19,14 @@ python3.pkgs.buildPythonApplication {
   postPatch = ''
     # https://github.com/megadose/holehe/pull/178
     substituteInPlace setup.py \
-      --replace "bs4" "beautifulsoup4"
+      --replace-fail "bs4" "beautifulsoup4"
   '';
 
-  propagatedBuildInputs = with python3.pkgs; [
+  build-system = with python3.pkgs; [
+    setuptools
+  ];
+
+  dependencies = with python3.pkgs; [
     beautifulsoup4
     colorama
     httpx
diff --git a/pkgs/by-name/ht/httpstat/package.nix b/pkgs/by-name/ht/httpstat/package.nix
index c80eeeb9e8ea..e26f52ffd092 100644
--- a/pkgs/by-name/ht/httpstat/package.nix
+++ b/pkgs/by-name/ht/httpstat/package.nix
@@ -9,13 +9,16 @@
 python3Packages.buildPythonApplication rec {
   pname = "httpstat";
   version = "1.3.1";
-  format = "setuptools";
+  format = "pyproject";
   src = fetchFromGitHub {
     owner = "reorx";
     repo = "httpstat";
     rev = version;
     sha256 = "sha256-zUdis41sQpJ1E3LdNwaCVj6gexi/Rk21IBUgoFISiDM=";
   };
+
+  build-system = with python3Packages; [ setuptools ];
+
   doCheck = false; # No tests
   buildInputs = [ glibcLocales ];
   runtimeDeps = [ curl ];
diff --git a/pkgs/by-name/hy/hyp/package.nix b/pkgs/by-name/hy/hyp/package.nix
index e084aba76528..35ed214941a8 100644
--- a/pkgs/by-name/hy/hyp/package.nix
+++ b/pkgs/by-name/hy/hyp/package.nix
@@ -7,13 +7,17 @@
 python3Packages.buildPythonPackage rec {
   pname = "hyp-server";
   version = "1.2.0";
-  format = "setuptools";
+  format = "pyproject";
 
   src = fetchPypi {
     inherit pname version;
     sha256 = "1lafjdcn9nnq6xc3hhyizfwh6l69lc7rixn6dx65aq71c913jc15";
   };
 
+  build-system = with python3Packages; [
+    setuptools
+  ];
+
   meta = with lib; {
     description = "Hyperminimal https server";
     mainProgram = "hyp";