diff --git a/pkgs/development/libraries/at-spi2-core/default.nix b/pkgs/development/libraries/at-spi2-core/default.nix
index 2a47de8d5643..f144ec1dad6b 100644
--- a/pkgs/development/libraries/at-spi2-core/default.nix
+++ b/pkgs/development/libraries/at-spi2-core/default.nix
@@ -1,7 +1,6 @@
 { lib
 , stdenv
 , fetchurl
-, fetchpatch
 , meson
 , ninja
 , pkg-config
@@ -24,23 +23,15 @@
 
 stdenv.mkDerivation rec {
   pname = "at-spi2-core";
-  version = "2.48.3";
+  version = "2.49.90";
 
   outputs = [ "out" "dev" ];
 
   src = fetchurl {
     url = "mirror://gnome/sources/${pname}/${lib.versions.majorMinor version}/${pname}-${version}.tar.xz";
-    sha256 = "NzFt9DypmJzlOdVM9CmnaMKLs4oLNJUL6t0EIYJ+31U=";
+    sha256 = "HmYSdV1xu+lSFW3AUbKB0aQyalaWrDu8jP1ayP2XHxg=";
   };
 
-  patches = [
-    # Fix implicit declaration of `strcasecmp`, which is an error on clang 16.
-    (fetchpatch {
-      url = "https://gitlab.gnome.org/GNOME/at-spi2-core/-/merge_requests/147.patch";
-      hash = "sha256-UU2n//Z9F1SyUGyuDKsiwZDyThsp/tJprz/zolDDTyw=";
-    })
-  ];
-
   nativeBuildInputs = [
     glib
     meson