diff --git a/pkgs/by-name/re/remmina/package.nix b/pkgs/by-name/re/remmina/package.nix
index 14faf6c54cf9..eadf47a271b9 100644
--- a/pkgs/by-name/re/remmina/package.nix
+++ b/pkgs/by-name/re/remmina/package.nix
@@ -124,6 +124,9 @@ stdenv.mkDerivation (finalAttrs: {
       "-DHAVE_LIBAPPINDICATOR=OFF"
       "-DWITH_CUPS=OFF"
       "-DWITH_ICON_CACHE=OFF"
+      # Don't use system installed Python like on GitHub Actions runners
+      "-DPYTHON_INCLUDE_DIR=${python3}/include/${python3.libPrefix}"
+      "-DPYTHON_LIBRARY=${python3}/lib/libpython${python3.pythonVersion}${stdenv.hostPlatform.extensions.sharedLibrary}"
     ];
 
   dontWrapQtApps = true;
@@ -135,6 +138,7 @@ stdenv.mkDerivation (finalAttrs: {
       ${lib.optionalString stdenv.hostPlatform.isDarwin ''
         --prefix XDG_DATA_DIRS : "$XDG_ICON_DIRS"
       ''}
+      --prefix PATH : "${lib.makeBinPath [ python3 ]}"
     )
   '';