diff --git a/pkgs/development/python-modules/grpcio-status/default.nix b/pkgs/development/python-modules/grpcio-status/default.nix
index 173353fc9f2f..4e72e19392ff 100644
--- a/pkgs/development/python-modules/grpcio-status/default.nix
+++ b/pkgs/development/python-modules/grpcio-status/default.nix
@@ -9,14 +9,14 @@
 
 buildPythonPackage rec {
   pname = "grpcio-status";
-  version = "1.45.0";
+  version = "1.46.1";
   format = "setuptools";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-S6rY6Ow8RHiOA4wk49fccCWeBroJ9ApbgXhThWO6Plo=";
+    sha256 = "700ad7bdc2da6b1d873ae9abffd957b3df6b74c8ca4b34c50bf1b062ae10a620";
   };
 
   propagatedBuildInputs = [