diff --git a/pkgs/development/python-modules/POT/default.nix b/pkgs/development/python-modules/POT/default.nix
new file mode 100644
index 000000000000..a72303f6b4cc
--- /dev/null
+++ b/pkgs/development/python-modules/POT/default.nix
@@ -0,0 +1,54 @@
+{ lib
+, fetchPypi
+, buildPythonPackage
+, numpy
+, scipy
+, cython
+, matplotlib
+, scikit-learn
+, cupy
+, pymanopt
+, autograd
+, pytestCheckHook
+, enableDimensionalityReduction ? false
+, enableGPU ? false
+}:
+
+buildPythonPackage rec {
+  pname = "pot";
+  version = "0.7.0";
+
+  src = fetchPypi {
+    pname = "POT";
+    inherit version;
+    sha256 = "01mdsiv8rlgqzvm3bds9aj49khnn33i523c2cqqrl10zg742pb6l";
+  };
+
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "--cov-report= --cov=ot" \
+                ""
+  '';
+
+  nativeBuildInputs = [ numpy cython ];
+  propagatedBuildInputs = [ numpy scipy ]
+    ++ lib.optionals enableGPU [ cupy ]
+    ++ lib.optionals enableDimensionalityReduction [ pymanopt autograd ];
+  checkInputs = [ matplotlib scikit-learn pytestCheckHook ];
+
+  preCheck = ''
+    rm -r ot
+  '';
+
+  # GPU tests are always skipped because of sandboxing
+  disabledTests = [ "warnings" ];
+
+  pythonImportsCheck = [ "ot" "ot.lp" ];
+
+  meta = {
+    description = "Python Optimal Transport Library";
+    homepage = "https://pythonot.github.io/";
+    license = lib.licenses.mit;
+    maintainers = with lib.maintainers; [ yl3dy ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 14e2f7759f62..e64ac018cbbd 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5571,6 +5571,8 @@ in {
 
   postorius = callPackage ../servers/mail/mailman/postorius.nix { };
 
+  POT = callPackage ../development/python-modules/POT { };
+
   potr = callPackage ../development/python-modules/potr { };
 
   power = callPackage ../development/python-modules/power { };