diff --git a/pkgs/development/python-modules/matplotlib/default.nix b/pkgs/development/python-modules/matplotlib/default.nix
index 4c23466b9880..926dd2467971 100644
--- a/pkgs/development/python-modules/matplotlib/default.nix
+++ b/pkgs/development/python-modules/matplotlib/default.nix
@@ -4,6 +4,7 @@
   fetchPypi,
   buildPythonPackage,
   isPyPy,
+  pythonAtLeast,
   pythonOlder,
 
   # build-system
@@ -52,7 +53,8 @@
 
   # Tk
   # Darwin has its own "MacOSX" backend, PyPy has tkagg backend and does not support tkinter
-  enableTk ? (!stdenv.hostPlatform.isDarwin && !isPyPy),
+  # tkinter fails to build on Python 3.11
+  enableTk ? (!stdenv.hostPlatform.isDarwin && !isPyPy && pythonAtLeast "3.12"),
   tkinter,
 
   # Qt