diff --git a/pkgs/development/interpreters/python/cpython/default.nix b/pkgs/development/interpreters/python/cpython/default.nix
index 6778dc460e05..4e60b15ba4cb 100644
--- a/pkgs/development/interpreters/python/cpython/default.nix
+++ b/pkgs/development/interpreters/python/cpython/default.nix
@@ -195,25 +195,22 @@ let
         if parsed.cpu.significantByte.name == "littleEndian" then "arm" else "armeb"
       else if isx86_32 then "i386"
       else parsed.cpu.name;
-    # Python doesn't distinguish musl and glibc and always prefixes with "gnu"
-    gnuAbiName = replaceStrings [ "musl" ] [ "gnu" ] parsed.abi.name;
-    pythonAbiName =
-      # python's build doesn't support every gnu<extension>, and doesn't
-      # differentiate between musl and glibc, so we list those supported in
-      # here:
+
+    pythonAbiName = let
+      # python's build doesn't match the nixpkgs abi in some cases.
       # https://github.com/python/cpython/blob/e488e300f5c01289c10906c2e53a8e43d6de32d8/configure.ac#L724
-      # Note: this is an approximation, as it doesn't take into account the CPU
-      # family, or the nixpkgs abi naming conventions.
-      if elem gnuAbiName [
-        "gnux32"
-        "gnueabihf"
-        "gnueabi"
-        "gnuabin32"
-        "gnuabi64"
-        "gnuspe"
-      ]
-      then gnuAbiName
-      else "gnu";
+      nixpkgsPythonAbiMappings = {
+        "gnuabielfv2" = "gnu";
+        "muslabielfv2" = "musl";
+      };
+      pythonAbi = nixpkgsPythonAbiMappings.${parsed.abi.name} or parsed.abi.name;
+    in
+      # Python <3.11 doesn't distinguish musl and glibc and always prefixes with "gnu"
+      if lib.versionOlder version "3.11" then
+        replaceStrings [ "musl" ] [ "gnu" ] pythonAbi
+      else
+        pythonAbi;
+
     multiarch =
       if isDarwin then "darwin"
       else if isWindows then ""