diff --git a/pkgs/development/python-modules/ghostscript/default.nix b/pkgs/development/python-modules/ghostscript/default.nix
new file mode 100644
index 000000000000..34d88bd2c91d
--- /dev/null
+++ b/pkgs/development/python-modules/ghostscript/default.nix
@@ -0,0 +1,63 @@
+{
+  stdenv,
+  lib,
+  buildPythonPackage,
+  fetchFromGitLab,
+  pytestCheckHook,
+
+  setuptools,
+
+  ghostscript_headless,
+}:
+
+buildPythonPackage rec {
+  pname = "ghostscript";
+  version = "0.7";
+  pyproject = true;
+
+  src = fetchFromGitLab {
+    owner = "pdftools";
+    repo = "python-ghostscript";
+    tag = "v${version}";
+    hash = "sha256-yBJuAnLK/4YDU9PBsSWPQay4pDws3bP+3rCplysq41w=";
+  };
+
+  postPatch =
+    let
+      extLib = stdenv.hostPlatform.extensions.sharedLibrary;
+    in
+    ''
+      substituteInPlace ghostscript/__init__.py \
+        --replace-fail '__version__ = gs.__version__' '__version__ = "${version}"'
+
+      substituteInPlace ghostscript/_gsprint.py \
+        --replace-fail 'cdll.LoadLibrary("libgs.so")' 'cdll.LoadLibrary("${lib.getLib ghostscript_headless}/lib/libgs${extLib}")'
+    '';
+
+  build-system = [
+    setuptools
+  ];
+
+  nativeCheckInputs = [
+    pytestCheckHook
+  ];
+
+  disabledTests = [
+    # Some tests don't (fully) match anymore.
+    # Not sure if ghostscript ever promised to keep producing the same outputs, bit-by-bit…
+    "test_simple"
+    "test_unicode_arguments"
+    "test_run_string"
+    "test_stdin"
+  ];
+
+  pythonImportsCheck = [ "ghostscript" ];
+
+  meta = {
+    description = "Interface to the Ghostscript C-API using ctypes.";
+    homepage = "https://gitlab.com/pdftools/python-ghostscript";
+    changelog = "https://gitlab.com/pdftools/python-ghostscript/-/blob/v${version}/CHANGES.txt";
+    license = lib.licenses.gpl3Plus;
+    maintainers = with lib.maintainers; [ flokli ];
+  };
+}
diff --git a/pkgs/development/python-modules/img2pdf/default.nix b/pkgs/development/python-modules/img2pdf/default.nix
index 1d29ce17352a..08f676729163 100644
--- a/pkgs/development/python-modules/img2pdf/default.nix
+++ b/pkgs/development/python-modules/img2pdf/default.nix
@@ -1,5 +1,6 @@
 {
   lib,
+  pkgs,
   buildPythonPackage,
   fetchFromGitea,
   fetchpatch,
@@ -10,7 +11,6 @@
   pillow,
   stdenv,
   exiftool,
-  ghostscript,
   imagemagick,
   mupdf-headless,
   netpbm,
@@ -67,7 +67,7 @@ buildPythonPackage rec {
 
   nativeCheckInputs = [
     exiftool
-    ghostscript
+    pkgs.ghostscript
     imagemagick
     mupdf-headless
     netpbm
diff --git a/pkgs/development/python-modules/pdfplumber/default.nix b/pkgs/development/python-modules/pdfplumber/default.nix
index 5130c287c9c1..3678634fd942 100644
--- a/pkgs/development/python-modules/pdfplumber/default.nix
+++ b/pkgs/development/python-modules/pdfplumber/default.nix
@@ -1,8 +1,8 @@
 {
   lib,
+  pkgs,
   buildPythonPackage,
   fetchFromGitHub,
-  ghostscript,
   jupyterlab,
   nbexec,
   pandas,
@@ -42,7 +42,7 @@ buildPythonPackage rec {
   '';
 
   nativeCheckInputs = [
-    ghostscript
+    pkgs.ghostscript
     jupyterlab
     nbexec
     pandas
diff --git a/pkgs/development/python-modules/pydyf/default.nix b/pkgs/development/python-modules/pydyf/default.nix
index 46a001bb1c26..8f9b12f17c0a 100644
--- a/pkgs/development/python-modules/pydyf/default.nix
+++ b/pkgs/development/python-modules/pydyf/default.nix
@@ -1,9 +1,9 @@
 {
+  pkgs,
   lib,
   buildPythonPackage,
   fetchPypi,
   flit-core,
-  ghostscript,
   pillow,
   pytestCheckHook,
   pytest-cov-stub,
@@ -30,7 +30,7 @@ buildPythonPackage rec {
   nativeBuildInputs = [ flit-core ];
 
   nativeCheckInputs = [
-    ghostscript
+    pkgs.ghostscript
     pillow
     pytestCheckHook
     pytest-cov-stub
diff --git a/pkgs/development/python-modules/weasyprint/default.nix b/pkgs/development/python-modules/weasyprint/default.nix
index 36824cdcc2ff..696bee47ac5f 100644
--- a/pkgs/development/python-modules/weasyprint/default.nix
+++ b/pkgs/development/python-modules/weasyprint/default.nix
@@ -1,4 +1,7 @@
 {
+  stdenv,
+  lib,
+  pkgs,
   buildPythonPackage,
   cffi,
   cssselect2,
@@ -6,10 +9,8 @@
   flit-core,
   fontconfig,
   fonttools,
-  ghostscript,
   glib,
   harfbuzz,
-  lib,
   pango,
   pillow,
   pydyf,
@@ -18,7 +19,6 @@
   pytestCheckHook,
   pythonOlder,
   replaceVars,
-  stdenv,
   tinycss2,
   tinyhtml5,
 }:
@@ -61,7 +61,7 @@ buildPythonPackage rec {
   ] ++ fonttools.optional-dependencies.woff;
 
   nativeCheckInputs = [
-    ghostscript
+    pkgs.ghostscript
     pytest-cov-stub
     pytestCheckHook
   ];
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 15b2df126598..6b4e3e795bd7 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -5551,6 +5551,8 @@ self: super: with self; {
 
   ghome-foyer-api = callPackage ../development/python-modules/ghome-foyer-api { };
 
+  ghostscript = callPackage ../development/python-modules/ghostscript { };
+
   ghp-import = callPackage ../development/python-modules/ghp-import { };
 
   ghrepo-stats = callPackage ../development/python-modules/ghrepo-stats { };