diff --git a/pkgs/by-name/om/omnissa-horizon-client/package.nix b/pkgs/by-name/om/omnissa-horizon-client/package.nix
index bcc6acb420eb..a29d00151f07 100644
--- a/pkgs/by-name/om/omnissa-horizon-client/package.nix
+++ b/pkgs/by-name/om/omnissa-horizon-client/package.nix
@@ -8,6 +8,8 @@
   makeDesktopItem,
   makeWrapper,
   opensc,
+  liberation_ttf,
+  writeText,
   writeTextDir,
   configText ? "",
 }:
@@ -26,11 +28,42 @@ let
 
   mainProgram = "horizon-client";
 
+  # Horizon renders its broker/desktop launch-item (tile) labels with
+  # "DejaVu Sans", but fails to instantiate the font when fontconfig resolves it
+  # to a symlinked file -- which is exactly what nixpkgs' dejavu_fonts provides
+  # (it is a symlink tree into dejavu-fonts-minimal). The labels then render as
+  # blank boxes; the rest of the UI uses the GTK theme font and is unaffected.
+  # Other toolkits load the same symlinked font without issue, so this is
+  # specific to the client's font handling.
+  #
+  # The FHS sandbox bind-mounts the host's /etc/fonts, so the FHS environment's
+  # own fontconfig does not apply. Point the client at a config that keeps the
+  # host's fonts but maps "DejaVu Sans" onto a bundled, regular-file font
+  # (Liberation Sans). This is deterministic and independent of the host's
+  # font configuration.
+  fontconfigFile = writeText "omnissa-horizon-fontconfig.conf" ''
+    <?xml version="1.0"?>
+    <!DOCTYPE fontconfig SYSTEM "urn:fontconfig:fonts.dtd">
+    <fontconfig>
+      <include ignore_missing="yes">/etc/fonts/fonts.conf</include>
+      <dir>${liberation_ttf}/share/fonts</dir>
+      <match target="pattern">
+        <test name="family" qual="any">
+          <string>DejaVu Sans</string>
+        </test>
+        <edit name="family" mode="assign" binding="same">
+          <string>Liberation Sans</string>
+        </edit>
+      </match>
+    </fontconfig>
+  '';
+
   # This forces the default GTK theme (Adwaita) because Horizon is prone to
   # UI usability issues when using non-default themes, such as Adwaita-dark.
   wrapBinCommands = path: name: ''
     makeWrapper "$out/${path}/${name}" "$out/bin/${name}_wrapper" \
     --set GTK_THEME Adwaita \
+    --set FONTCONFIG_FILE "${fontconfigFile}" \
     --suffix XDG_DATA_DIRS : "${gsettings-desktop-schemas}/share/gsettings-schemas/${gsettings-desktop-schemas.name}" \
     --suffix LD_LIBRARY_PATH : "$out/lib/omnissa/horizon/crtbora:$out/lib/omnissa"
   '';