diff --git a/pkgs/development/python-modules/griffecli/default.nix b/pkgs/development/python-modules/griffecli/default.nix
new file mode 100644
index 000000000000..735f3ea4daa1
--- /dev/null
+++ b/pkgs/development/python-modules/griffecli/default.nix
@@ -0,0 +1,46 @@
+{
+  lib,
+  buildPythonPackage,
+  colorama,
+  fetchFromGitHub,
+  griffelib,
+  hatchling,
+  pdm-backend,
+  uv-dynamic-versioning,
+}:
+
+buildPythonPackage (finalAttrs: {
+  pname = "griffecli";
+  version = "2.1.0";
+  pyproject = true;
+
+  src = fetchFromGitHub {
+    owner = "mkdocstrings";
+    repo = "griffe";
+    tag = finalAttrs.version;
+    hash = "sha256-hNKL86LSE9PwIofxt2t5PrlThiX7hTgYADK2HDVhNjk=";
+  };
+
+  sourceRoot = "${finalAttrs.src.name}/packages/griffecli";
+
+  build-system = [
+    hatchling
+    pdm-backend
+    uv-dynamic-versioning
+  ];
+
+  dependencies = [
+    colorama
+    griffelib
+  ];
+
+  pythonImportsCheck = [ "griffecli" ];
+
+  meta = {
+    description = "Signatures for entire Python programs. Extract the structure, the frame, the skeleton of your project, to generate API documentation or find breaking changes in your API";
+    homepage = "https://github.com/mkdocstrings/griffe";
+    changelog = "https://github.com/mkdocstrings/griffe/releases/tag/${finalAttrs.src.tag}";
+    license = lib.licenses.isc;
+    maintainers = with lib.maintainers; [ fab ];
+  };
+})
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 0a7fe3a0c65c..a2dc7df387c7 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -6848,6 +6848,8 @@ self: super: with self; {
 
   griffe = callPackage ../development/python-modules/griffe { };
 
+  griffecli = callPackage ../development/python-modules/griffecli { };
+
   griffelib = callPackage ../development/python-modules/griffelib { };
 
   grip = callPackage ../development/python-modules/grip { };