diff --git a/pkgs/applications/science/math/cemu-ti/cmake-no-deploy.patch b/pkgs/applications/science/math/cemu-ti/cmake-no-deploy.patch
new file mode 100644
index 000000000000..919dbc05331d
--- /dev/null
+++ b/pkgs/applications/science/math/cemu-ti/cmake-no-deploy.patch
@@ -0,0 +1,13 @@
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index 68ce1294..5c2924f6 100644
+--- a/CMakeLists.txt
++++ b/CMakeLists.txt
+@@ -350,7 +350,7 @@ message("Binary dir: ${CMAKE_CURRENT_BINARY_DIR}")
+
+ # TODO: linux .desktop/.xml files
+
+-if(COMMAND qt_generate_deploy_app_script)
++if(FALSE)
+     qt_generate_deploy_app_script(
+         TARGET CEmu
+         FILENAME_VARIABLE deploy_script
diff --git a/pkgs/applications/science/math/cemu-ti/default.nix b/pkgs/applications/science/math/cemu-ti/default.nix
index 01e1602406fd..1a4f3c253513 100644
--- a/pkgs/applications/science/math/cemu-ti/default.nix
+++ b/pkgs/applications/science/math/cemu-ti/default.nix
@@ -26,6 +26,8 @@ stdenv.mkDerivation (finalAttrs: {
     # This is resolved upstream, but I can't apply the patch because the
     # sourceRoot isn't set to the base of the Git repo.
     ./resolve-ambiguous-constexpr.patch
+    # Disable the deploy_script generation. It's broken with Qt 6.10 and not used by this package.
+    ./cmake-no-deploy.patch
   ];
 
   nativeBuildInputs = [