diff --git a/pkgs/development/compilers/ghc/8.10.7.nix b/pkgs/development/compilers/ghc/8.10.7.nix
index 873925417c16..8874f4221e81 100644
--- a/pkgs/development/compilers/ghc/8.10.7.nix
+++ b/pkgs/development/compilers/ghc/8.10.7.nix
@@ -72,7 +72,6 @@ assert !enableIntegerSimple -> gmp != null;
 assert (stdenv.targetPlatform != stdenv.hostPlatform) -> !enableHaddockProgram;
 
 let
-  libffi_name = if stdenv.isDarwin && stdenv.isAarch64 then "libffi" else "libffi_3_3";
   inherit (stdenv) buildPlatform hostPlatform targetPlatform;
 
   inherit (bootPkgs) ghc;
@@ -191,6 +190,36 @@ let
     (lib.optionalString enableIntegerSimple "-integer-simple")
   ];
 
+  libffi_name = if stdenv.isDarwin && stdenv.isAarch64 then "libffi" else "libffi_3_3";
+
+  # These libraries are library dependencies of the standard libraries bundled
+  # by GHC (core libs) users will link their compiled artifacts again. Thus,
+  # they should be taken from targetPackages.
+  #
+  # We need to use pkgsHostTarget if we are cross compiling a native GHC compiler,
+  # though (when native compiling GHC, pkgsHostTarget == targetPackages):
+  #
+  # 1. targetPackages would be empty(-ish) in this situation since we can't
+  #    execute cross compiled compilers in order to obtain the libraries
+  #    that would be in targetPackages.
+  # 2. pkgsHostTarget is fine to use since hostPlatform == targetPlatform in this
+  #    situation.
+  # 3. The core libs used by the final GHC (stage 2) for user artifacts are also
+  #    used to build stage 2 GHC itself, i.e. the core libs are both host and
+  #    target.
+  targetLibs =
+    let
+      basePackageSet =
+        if hostPlatform != targetPlatform
+        then targetPackages
+        else pkgsHostTarget;
+    in
+      {
+        inherit (basePackageSet) gmp;
+        # dynamic inherits are not possible in Nix
+        libffi = basePackageSet.${libffi_name};
+      };
+
 in
 
 # C compiler, bintools and LLVM are used at build time, but will also leak into
@@ -348,11 +377,11 @@ stdenv.mkDerivation (rec {
     "--datadir=$doc/share/doc/ghc"
   ] ++ lib.optionals (args.${libffi_name} != null) [
     "--with-system-libffi"
-    "--with-ffi-includes=${targetPackages.${libffi_name}.dev}/include"
-    "--with-ffi-libraries=${targetPackages.${libffi_name}.out}/lib"
+    "--with-ffi-includes=${targetLibs.libffi.dev}/include"
+    "--with-ffi-libraries=${targetLibs.libffi.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && !enableIntegerSimple) [
-    "--with-gmp-includes=${targetPackages.gmp.dev}/include"
-    "--with-gmp-libraries=${targetPackages.gmp.out}/lib"
+    "--with-gmp-includes=${targetLibs.gmp.dev}/include"
+    "--with-gmp-libraries=${targetLibs.gmp.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && hostPlatform.libc != "glibc" && !targetPlatform.isWindows) [
     "--with-iconv-includes=${libiconv}/include"
     "--with-iconv-libraries=${libiconv}/lib"
diff --git a/pkgs/development/compilers/ghc/common-hadrian.nix b/pkgs/development/compilers/ghc/common-hadrian.nix
index 78e0e2dd167e..11d6059a5616 100644
--- a/pkgs/development/compilers/ghc/common-hadrian.nix
+++ b/pkgs/development/compilers/ghc/common-hadrian.nix
@@ -324,6 +324,29 @@ let
     (lib.optionalString enableNativeBignum "-native-bignum")
   ];
 
+  # These libraries are library dependencies of the standard libraries bundled
+  # by GHC (core libs) users will link their compiled artifacts again. Thus,
+  # they should be taken from targetPackages.
+  #
+  # We need to use pkgsHostTarget if we are cross compiling a native GHC compiler,
+  # though (when native compiling GHC, pkgsHostTarget == targetPackages):
+  #
+  # 1. targetPackages would be empty(-ish) in this situation since we can't
+  #    execute cross compiled compilers in order to obtain the libraries
+  #    that would be in targetPackages.
+  # 2. pkgsHostTarget is fine to use since hostPlatform == targetPlatform in this
+  #    situation.
+  # 3. The core libs used by the final GHC (stage 2) for user artifacts are also
+  #    used to build stage 2 GHC itself, i.e. the core libs are both host and
+  #    target.
+  targetLibs = {
+    inherit
+      (if hostPlatform != targetPlatform then targetPackages else pkgsHostTarget)
+      elfutils
+      gmp
+      libffi;
+  };
+
 in
 
 # C compiler, bintools and LLVM are used at build time, but will also leak into
@@ -447,11 +470,11 @@ stdenv.mkDerivation ({
     "--datadir=$doc/share/doc/ghc"
   ] ++ lib.optionals (libffi != null && !targetPlatform.isGhcjs) [
     "--with-system-libffi"
-    "--with-ffi-includes=${targetPackages.libffi.dev}/include"
-    "--with-ffi-libraries=${targetPackages.libffi.out}/lib"
+    "--with-ffi-includes=${targetLibs.libffi.dev}/include"
+    "--with-ffi-libraries=${targetLibs.libffi.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && !enableNativeBignum) [
-    "--with-gmp-includes=${targetPackages.gmp.dev}/include"
-    "--with-gmp-libraries=${targetPackages.gmp.out}/lib"
+    "--with-gmp-includes=${targetLibs.gmp.dev}/include"
+    "--with-gmp-libraries=${targetLibs.gmp.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && hostPlatform.libc != "glibc" && !targetPlatform.isWindows) [
     "--with-iconv-includes=${libiconv}/include"
     "--with-iconv-libraries=${libiconv}/lib"
@@ -465,8 +488,8 @@ stdenv.mkDerivation ({
     "--disable-large-address-space"
   ] ++ lib.optionals enableDwarf [
     "--enable-dwarf-unwind"
-    "--with-libdw-includes=${lib.getDev targetPackages.elfutils}/include"
-    "--with-libdw-libraries=${lib.getLib targetPackages.elfutils}/lib"
+    "--with-libdw-includes=${lib.getDev targetLibs.elfutils}/include"
+    "--with-libdw-libraries=${lib.getLib targetLibs.elfutils}/lib"
   ] ++ lib.optionals targetPlatform.isDarwin [
     # Darwin uses llvm-ar. GHC will try to use `-L` with `ar` when it is `llvm-ar`
     # but it doesn’t currently work because Cabal never uses `-L` on Darwin. See:
diff --git a/pkgs/development/compilers/ghc/common-make-native-bignum.nix b/pkgs/development/compilers/ghc/common-make-native-bignum.nix
index 3d5d9d6329a5..812bb8fa95ab 100644
--- a/pkgs/development/compilers/ghc/common-make-native-bignum.nix
+++ b/pkgs/development/compilers/ghc/common-make-native-bignum.nix
@@ -191,6 +191,28 @@ let
     (lib.optionalString enableNativeBignum "-native-bignum")
   ];
 
+  # These libraries are library dependencies of the standard libraries bundled
+  # by GHC (core libs) users will link their compiled artifacts again. Thus,
+  # they should be taken from targetPackages.
+  #
+  # We need to use pkgsHostTarget if we are cross compiling a native GHC compiler,
+  # though (when native compiling GHC, pkgsHostTarget == targetPackages):
+  #
+  # 1. targetPackages would be empty(-ish) in this situation since we can't
+  #    execute cross compiled compilers in order to obtain the libraries
+  #    that would be in targetPackages.
+  # 2. pkgsHostTarget is fine to use since hostPlatform == targetPlatform in this
+  #    situation.
+  # 3. The core libs used by the final GHC (stage 2) for user artifacts are also
+  #    used to build stage 2 GHC itself, i.e. the core libs are both host and
+  #    target.
+  targetLibs = {
+    inherit
+      (if hostPlatform != targetPlatform then targetPackages else pkgsHostTarget)
+      gmp
+      libffi;
+  };
+
 in
 
 # C compiler, bintools and LLVM are used at build time, but will also leak into
@@ -366,11 +388,11 @@ stdenv.mkDerivation (rec {
     "--datadir=$doc/share/doc/ghc"
   ] ++ lib.optionals (libffi != null) [
     "--with-system-libffi"
-    "--with-ffi-includes=${targetPackages.libffi.dev}/include"
-    "--with-ffi-libraries=${targetPackages.libffi.out}/lib"
+    "--with-ffi-includes=${targetLibs.libffi.dev}/include"
+    "--with-ffi-libraries=${targetLibs.libffi.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && !enableNativeBignum) [
-    "--with-gmp-includes=${targetPackages.gmp.dev}/include"
-    "--with-gmp-libraries=${targetPackages.gmp.out}/lib"
+    "--with-gmp-includes=${targetLibs.gmp.dev}/include"
+    "--with-gmp-libraries=${targetLibs.gmp.out}/lib"
   ] ++ lib.optionals (targetPlatform == hostPlatform && hostPlatform.libc != "glibc" && !targetPlatform.isWindows) [
     "--with-iconv-includes=${libiconv}/include"
     "--with-iconv-libraries=${libiconv}/lib"