diff --git a/pkgs/development/python-modules/vllm/default.nix b/pkgs/development/python-modules/vllm/default.nix
index 0c14e61f4b87..187f2884d97d 100644
--- a/pkgs/development/python-modules/vllm/default.nix
+++ b/pkgs/development/python-modules/vllm/default.nix
@@ -427,5 +427,11 @@ buildPythonPackage rec {
       happysalada
       lach
     ];
+    badPlatforms = [
+      # CMake Error at cmake/cpu_extension.cmake:78 (find_isa):
+      # find_isa Function invoked with incorrect arguments for function named:
+      # find_isa
+      "x86_64-darwin"
+    ];
   };
 }