diff --git a/pkgs/tools/admin/pgadmin/default.nix b/pkgs/tools/admin/pgadmin/default.nix
index 8f1af271341d..ab78cdeee48c 100644
--- a/pkgs/tools/admin/pgadmin/default.nix
+++ b/pkgs/tools/admin/pgadmin/default.nix
@@ -13,15 +13,17 @@
   libtool,
   libpng,
   nasm,
+  cmake,
   pkg-config,
   stdenv,
+  srcOnly,
   server-mode ? true,
 }:
 
 let
   pname = "pgadmin";
   version = "9.3";
-  yarnHash = "sha256-75FwwQ67j0aTHGvD4YwAaR8CWV4u4KsuMghidbkgVsw=";
+  yarnHash = "sha256-T6RKWuAAoJgbzJKef4ioOoUDtoGM9s9BFqxFdy5EtyQ=";
 
   src = fetchFromGitHub {
     owner = "pgadmin-org";
@@ -30,6 +32,13 @@ let
     hash = "sha256-4uupF1dw6OE/briAI5PWiQ7h6RPx1sUqf8PB8cJsNSU=";
   };
 
+  mozjpeg-bin = fetchFromGitHub {
+    owner = "imagemin";
+    repo = "mozjpeg-bin";
+    rev = "c0587fbc00b21ed8cad8bae499a0827baeaf7ffa";
+    hash = "sha256-D/pXQBlIIyk7KAgxJ1gKqxYxtlfBbLzUSmYZbH659cA=";
+  };
+
   # keep the scope, as it is used throughout the derivation and tests
   # this also makes potential future overrides easier
   pythonPackages = python3.pkgs.overrideScope (final: prev: { });
@@ -51,6 +60,14 @@ pythonPackages.buildPythonApplication rec {
   inherit pname version src;
 
   offlineCache = yarn-berry_3.fetchYarnBerryDeps {
+    # mozjpeg fails to build on darwin due to a hardocded path
+    # this has been fixed upstream on master but no new version
+    # has been released. We therefore point yarn to upstream
+    # see https://github.com/imagemin/mozjpeg-bin/issues/64
+    # and https://github.com/imagemin/mozjpeg-bin/issues/81
+    patches = [
+      ./mozjpeg.patch
+    ];
     src = src + "/web";
     hash = yarnHash;
   };
@@ -68,6 +85,11 @@ pythonPackages.buildPythonApplication rec {
   ];
 
   postPatch = ''
+    # the patch needs to be executed inside the /web subfolder
+    # therefore it is included here and not in `patches`
+    cd web
+    patch -u yarn.lock ${./mozjpeg.patch}
+    cd ..
     # patching Makefile, so it doesn't try to build sphinx documentation here
     # (will do so later)
     substituteInPlace Makefile \
@@ -89,6 +111,8 @@ pythonPackages.buildPythonApplication rec {
   '';
 
   dontYarnBerryInstallDeps = true;
+  env.YARN_ENABLE_SCRIPTS = "0";
+  dontUseCmakeConfigure = true;
 
   preBuild = ''
     # Adapted from pkg/pip/build.sh
@@ -117,6 +141,25 @@ pythonPackages.buildPythonApplication rec {
     export LD=$CC # https://github.com/imagemin/optipng-bin/issues/108
     yarnBerryConfigHook
     )
+    # mozjpeg vendored source isn't included in the checkout for yarn. If we copy it before the
+    # yarnConfigHook it will just get overwritten. So we first run the configHook without build,
+    # then copy the vendored source and then build the dependencies
+    # This has the disadvantage of repeating some of the yarnConfigHooks logic here
+    mkdir -p node_modules/mozjpeg/vendor/source
+    cp ${mozjpeg-bin}/vendor/source/mozjpeg.tar.gz node_modules/mozjpeg/vendor/source/
+    (
+    # https://github.com/mozilla/mozjpeg/issues/438
+    substituteInPlace node_modules/mozjpeg/lib/install.js --replace-fail "cmake -DCMAKE" "cmake -DENABLE_STATIC=FALSE -DCMAKE"
+    substituteInPlace node_modules/mozjpeg/lib/install.js --replace-fail "cp cjpeg-static" "cp cjpeg"
+    export LD=$CC
+    export HOME=$(mktemp -d)
+    export YARN_ENABLE_SCRIPTS=1
+    YARN_IGNORE_PATH=1 ${yarn-berry_3.yarn-berry-offline}/bin/yarn config set enableTelemetry false
+    YARN_IGNORE_PATH=1 ${yarn-berry_3.yarn-berry-offline}/bin/yarn config set enableGlobalCache false
+    export npm_config_nodedir="${srcOnly nodejs}"
+    export npm_config_node_gyp="${nodejs}/lib/node_modules/npm/node_modules/node-gyp/bin/node-gyp.js"
+    YARN_IGNORE_PATH=1 ${yarn-berry_3.yarn-berry-offline}/bin/yarn install --inline-builds
+    )
     yarn webpacker
     cp -r * ../pip-build/pgadmin4
     # save some disk space
@@ -147,6 +190,7 @@ pythonPackages.buildPythonApplication rec {
     nodejs
 
     # for building mozjpeg2
+    cmake
     autoconf
     automake
     libtool
diff --git a/pkgs/tools/admin/pgadmin/mozjpeg.patch b/pkgs/tools/admin/pgadmin/mozjpeg.patch
new file mode 100644
index 000000000000..dc73c7b4957a
--- /dev/null
+++ b/pkgs/tools/admin/pgadmin/mozjpeg.patch
@@ -0,0 +1,45 @@
+diff --git a/yarn.lock b/yarn.lock
+index fa189ef..54066a6 100644
+--- a/yarn.lock
++++ b/yarn.lock
+@@ -7299,6 +7299,23 @@ __metadata:
+   languageName: node
+   linkType: hard
+ 
++"execa@npm:^7.1.1":
++  version: 7.1.1
++  resolution: "execa@npm:7.1.1"
++  dependencies:
++    cross-spawn: ^7.0.3
++    get-stream: ^6.0.1
++    human-signals: ^3.0.1
++    is-stream: ^3.0.0
++    merge-stream: ^2.0.0
++    npm-run-path: ^5.1.0
++    onetime: ^6.0.0
++    signal-exit: ^3.0.7
++    strip-final-newline: ^3.0.0
++  checksum: 21fa46fc69314ace4068cf820142bdde5b643a5d89831c2c9349479c1555bff137a291b8e749e7efca36535e4e0a8c772c11008ca2e84d2cbd6ca141a3c8f937
++  languageName: node
++  linkType: hard
++
+ "executable@npm:^4.1.0":
+   version: 4.1.1
+   resolution: "executable@npm:4.1.1"
+@@ -11027,13 +11044,14 @@ __metadata:
+ 
+ "mozjpeg@npm:^8.0.0":
+   version: 8.0.0
+-  resolution: "mozjpeg@npm:8.0.0"
++  resolution: "mozjpeg@https://github.com/imagemin/mozjpeg-bin.git#commit=c0587fbc00b21ed8cad8bae499a0827baeaf7ffa"
+   dependencies:
+     bin-build: ^3.0.0
+     bin-wrapper: ^4.0.0
++    execa: ^7.1.1
+   bin:
+     mozjpeg: cli.js
+-  checksum: cba27c2efbc21a48434da1c6c8d6886988432430f958315fc59ef9b52bc2d6ee597e19f1cf6aae0fd611d5b2a113561fe2e85ec30a1ccd55c007340c638eb557
++  checksum: cba27c2efbc21a48434da1c6c8d6886988432430f958315fc59ef9b52bc2d6ee597e19f1cf6aae0fd611d5b2a113561fe2e85ec30a1ccd55c007340c638eb556
+   languageName: node
+   linkType: hard
+