diff --git a/pkgs/development/python-modules/msprime/default.nix b/pkgs/development/python-modules/msprime/default.nix
index b2e0cd54af53..4ea724ca1c60 100644
--- a/pkgs/development/python-modules/msprime/default.nix
+++ b/pkgs/development/python-modules/msprime/default.nix
@@ -17,12 +17,12 @@
 
 buildPythonPackage rec {
   pname = "msprime";
-  version = "1.3.4";
+  version = "1.4.1";
   pyproject = true;
 
   src = fetchPypi {
     inherit pname version;
-    hash = "sha256-0PlEo3pREx34zZZ5fyR5gXPEC6L/XAlFgdHKVvxRFzA=";
+    hash = "sha256-aKcgjq6jDKRzNlKHyDMHj2VK8eGGsk/AEF53F8k7uWc=";
   };
 
   postPatch = ''