diff --git a/pkgs/applications/networking/maestral-qt/default.nix b/pkgs/applications/networking/maestral-qt/default.nix
index 293b28e074c7..b351009d549c 100644
--- a/pkgs/applications/networking/maestral-qt/default.nix
+++ b/pkgs/applications/networking/maestral-qt/default.nix
@@ -14,8 +14,6 @@ python3.pkgs.buildPythonApplication rec {
   version = "1.9.5";
   pyproject = true;
 
-  disabled = python3.pythonOlder "3.7";
-
   src = fetchFromGitHub {
     owner = "SamSchott";
     repo = "maestral-qt";
diff --git a/pkgs/by-name/br/brutalmaze/package.nix b/pkgs/by-name/br/brutalmaze/package.nix
index 6c246383e93f..93982705deb1 100644
--- a/pkgs/by-name/br/brutalmaze/package.nix
+++ b/pkgs/by-name/br/brutalmaze/package.nix
@@ -8,7 +8,6 @@ python312Packages.buildPythonApplication rec {
   pname = "brutalmaze";
   version = "1.1.1";
   pyproject = true;
-  disabled = python312Packages.pythonOlder "3.7";
 
   src = fetchFromSourcehut {
     owner = "~cnx";
diff --git a/pkgs/by-name/dt/dt-schema/package.nix b/pkgs/by-name/dt/dt-schema/package.nix
index 098f74517f05..446e47f7b9ef 100644
--- a/pkgs/by-name/dt/dt-schema/package.nix
+++ b/pkgs/by-name/dt/dt-schema/package.nix
@@ -10,7 +10,6 @@ let
       # see https://github.com/devicetree-org/dt-schema/issues/108
       jsonschema = super.jsonschema.overridePythonAttrs (old: rec {
         version = "4.17.3";
-        disabled = self.pythonOlder "3.7";
 
         src = old.src.override {
           inherit version;
diff --git a/pkgs/by-name/gd/gdtoolkit_4/package.nix b/pkgs/by-name/gd/gdtoolkit_4/package.nix
index 23eabade70f8..253f4a131d93 100644
--- a/pkgs/by-name/gd/gdtoolkit_4/package.nix
+++ b/pkgs/by-name/gd/gdtoolkit_4/package.nix
@@ -37,8 +37,6 @@ python.pkgs.buildPythonApplication rec {
     hash = "sha256-Jam7Txm+Fq5zEkJZMmbWW5Ok4ThsPyi6NIeawQot0RE=";
   };
 
-  disabled = python.pythonOlder "3.7";
-
   propagatedBuildInputs = with python.pkgs; [
     docopt
     lark
diff --git a/pkgs/by-name/mu/mutmut/package.nix b/pkgs/by-name/mu/mutmut/package.nix
index 9fcec251b046..3604b653a107 100644
--- a/pkgs/by-name/mu/mutmut/package.nix
+++ b/pkgs/by-name/mu/mutmut/package.nix
@@ -20,8 +20,6 @@ python3Packages.buildPythonApplication rec {
     substituteInPlace requirements.txt --replace-fail 'junit-xml==1.8' 'junit-xml==1.9'
   '';
 
-  disabled = python3Packages.pythonOlder "3.7";
-
   doCheck = false;
 
   build-system = with python3Packages; [ setuptools ];
diff --git a/pkgs/by-name/of/offpunk/package.nix b/pkgs/by-name/of/offpunk/package.nix
index 462acbcc275e..01c0431ee483 100644
--- a/pkgs/by-name/of/offpunk/package.nix
+++ b/pkgs/by-name/of/offpunk/package.nix
@@ -17,8 +17,6 @@ python3Packages.buildPythonApplication rec {
   version = "2.8";
   pyproject = true;
 
-  disabled = python3Packages.pythonOlder "3.7";
-
   src = fetchFromSourcehut {
     owner = "~lioploum";
     repo = "offpunk";
diff --git a/pkgs/by-name/xc/xcat/package.nix b/pkgs/by-name/xc/xcat/package.nix
index cff20eecb07c..728d997d364a 100644
--- a/pkgs/by-name/xc/xcat/package.nix
+++ b/pkgs/by-name/xc/xcat/package.nix
@@ -7,7 +7,6 @@
 python3.pkgs.buildPythonApplication rec {
   pname = "xcat";
   version = "1.2.0";
-  disabled = python3.pythonOlder "3.7";
   pyproject = true;
 
   src = fetchFromGitHub {
diff --git a/pkgs/by-name/ze/zerobin/package.nix b/pkgs/by-name/ze/zerobin/package.nix
index ba73962d9833..1ff4b914e546 100644
--- a/pkgs/by-name/ze/zerobin/package.nix
+++ b/pkgs/by-name/ze/zerobin/package.nix
@@ -17,8 +17,6 @@ python3Packages.buildPythonApplication rec {
     sha256 = "1dfy3h823ylz4w2vv3mrmnmiyvf6rvyvsp4j3llr074w9id0zy16";
   };
 
-  disabled = python3Packages.pythonOlder "3.7";
-
   nativeBuildInputs = [
     python3Packages.doit
     python3Packages.pyscss
diff --git a/pkgs/development/python-modules/asynctest/default.nix b/pkgs/development/python-modules/asynctest/default.nix
index ffd3c0e7bdbf..62333d77a3a5 100644
--- a/pkgs/development/python-modules/asynctest/default.nix
+++ b/pkgs/development/python-modules/asynctest/default.nix
@@ -2,7 +2,6 @@
   lib,
   buildPythonPackage,
   fetchPypi,
-  pythonOlder,
   python,
   pythonAtLeast,
 }:
@@ -26,9 +25,6 @@ buildPythonPackage rec {
       --replace "test_events_watched_outside_test_are_ignored" "xtest_events_watched_outside_test_are_ignored"
   '';
 
-  # https://github.com/Martiusweb/asynctest/issues/132
-  doCheck = pythonOlder "3.7";
-
   checkPhase = ''
     ${python.interpreter} -m unittest test
   '';
diff --git a/pkgs/development/python-modules/fipy/default.nix b/pkgs/development/python-modules/fipy/default.nix
index c2dcdd60488d..40d8434a88d3 100644
--- a/pkgs/development/python-modules/fipy/default.nix
+++ b/pkgs/development/python-modules/fipy/default.nix
@@ -15,7 +15,6 @@
   openssh,
   fetchFromGitHub,
   pythonAtLeast,
-  pythonOlder,
 }:
 
 buildPythonPackage rec {
@@ -26,7 +25,7 @@ buildPythonPackage rec {
   # Python 3.12 is not yet supported.
   # https://github.com/usnistgov/fipy/issues/997
   # https://github.com/usnistgov/fipy/pull/1023
-  disabled = pythonOlder "3.7" || pythonAtLeast "3.12";
+  disabled = pythonAtLeast "3.12";
 
   src = fetchFromGitHub {
     owner = "usnistgov";
diff --git a/pkgs/development/python-modules/jupyter-server-fileid/default.nix b/pkgs/development/python-modules/jupyter-server-fileid/default.nix
index 7e39775da161..cb61e0d69844 100644
--- a/pkgs/development/python-modules/jupyter-server-fileid/default.nix
+++ b/pkgs/development/python-modules/jupyter-server-fileid/default.nix
@@ -1,7 +1,6 @@
 {
   lib,
   buildPythonPackage,
-  pythonOlder,
   fetchFromGitHub,
   hatchling,
   jupyter-events,
@@ -16,8 +15,6 @@ buildPythonPackage rec {
   version = "0.9.3";
   pyproject = true;
 
-  disables = pythonOlder "3.7";
-
   src = fetchFromGitHub {
     owner = "jupyter-server";
     repo = "jupyter_server_fileid";
diff --git a/pkgs/development/python-modules/lmtpd/default.nix b/pkgs/development/python-modules/lmtpd/default.nix
index 9e50439a0a1f..5f7f89a357c1 100644
--- a/pkgs/development/python-modules/lmtpd/default.nix
+++ b/pkgs/development/python-modules/lmtpd/default.nix
@@ -3,7 +3,6 @@
   buildPythonPackage,
   fetchPypi,
   pythonAtLeast,
-  pythonOlder,
   setuptools,
 }:
 
@@ -13,7 +12,7 @@ buildPythonPackage rec {
   pyproject = true;
 
   # smtpd will be removed in version 3.12
-  disabled = pythonOlder "3.7" || pythonAtLeast "3.12";
+  disabled = pythonAtLeast "3.12";
 
   src = fetchPypi {
     inherit pname version;
diff --git a/pkgs/development/python-modules/manifestoo-core/default.nix b/pkgs/development/python-modules/manifestoo-core/default.nix
index e74437bf5405..1235fef6fb30 100644
--- a/pkgs/development/python-modules/manifestoo-core/default.nix
+++ b/pkgs/development/python-modules/manifestoo-core/default.nix
@@ -1,12 +1,9 @@
 {
   buildPythonPackage,
-  typing-extensions,
   fetchPypi,
   lib,
   nix-update-script,
   hatch-vcs,
-  pythonOlder,
-  importlib-resources,
 }:
 
 buildPythonPackage rec {
@@ -22,10 +19,6 @@ buildPythonPackage rec {
 
   nativeBuildInputs = [ hatch-vcs ];
 
-  propagatedBuildInputs =
-    lib.optionals (pythonOlder "3.7") [ importlib-resources ]
-    ++ lib.optionals (pythonOlder "3.8") [ typing-extensions ];
-
   passthru.updateScript = nix-update-script { };
 
   meta = {
diff --git a/pkgs/development/python-modules/mezzanine/default.nix b/pkgs/development/python-modules/mezzanine/default.nix
index 08be1bf506e2..1c3ba200b8bb 100644
--- a/pkgs/development/python-modules/mezzanine/default.nix
+++ b/pkgs/development/python-modules/mezzanine/default.nix
@@ -14,7 +14,6 @@
   pytestCheckHook,
   pytest-cov-stub,
   pytest-django,
-  pythonOlder,
   pytz,
   requests,
   requests-oauthlib,
@@ -28,7 +27,7 @@ buildPythonPackage rec {
   version = "6.1.1";
   format = "setuptools";
 
-  disabled = pythonOlder "3.7" || isPyPy;
+  disabled = isPyPy;
 
   src = fetchFromGitHub {
     owner = "stephenmcd";
diff --git a/pkgs/development/python-modules/objgraph/default.nix b/pkgs/development/python-modules/objgraph/default.nix
index b249f096b331..7188d5daac6d 100644
--- a/pkgs/development/python-modules/objgraph/default.nix
+++ b/pkgs/development/python-modules/objgraph/default.nix
@@ -6,7 +6,6 @@
   graphvizPkgs,
   isPyPy,
   python,
-  pythonOlder,
   replaceVars,
   setuptools,
 }:
@@ -16,7 +15,7 @@ buildPythonPackage rec {
   version = "3.6.2";
   pyproject = true;
 
-  disabled = pythonOlder "3.7" || isPyPy;
+  disabled = isPyPy;
 
   src = fetchPypi {
     inherit pname version;
diff --git a/pkgs/development/python-modules/pyodbc/default.nix b/pkgs/development/python-modules/pyodbc/default.nix
index 5a308bc148bc..e84f991ae68e 100644
--- a/pkgs/development/python-modules/pyodbc/default.nix
+++ b/pkgs/development/python-modules/pyodbc/default.nix
@@ -3,7 +3,6 @@
   buildPythonPackage,
   fetchPypi,
   isPyPy,
-  pythonOlder,
   unixODBC,
 }:
 
@@ -12,7 +11,7 @@ buildPythonPackage rec {
   version = "5.2.0";
   format = "setuptools";
 
-  disabled = pythonOlder "3.7" || isPyPy; # use pypypdbc instead
+  disabled = isPyPy; # use pypypdbc instead
 
   src = fetchPypi {
     inherit pname version;
diff --git a/pkgs/development/python-modules/pyosmium/default.nix b/pkgs/development/python-modules/pyosmium/default.nix
index 2928d134a2c3..7ad9f2b2cc3f 100644
--- a/pkgs/development/python-modules/pyosmium/default.nix
+++ b/pkgs/development/python-modules/pyosmium/default.nix
@@ -10,7 +10,6 @@
   bzip2,
   zlib,
   pybind11,
-  pythonOlder,
   pytest-httpserver,
   pytestCheckHook,
   setuptools,
@@ -26,7 +25,7 @@ buildPythonPackage rec {
   version = "4.0.2";
   pyproject = true;
 
-  disabled = pythonOlder "3.7" || isPyPy;
+  disabled = isPyPy;
 
   src = fetchFromGitHub {
     owner = "osmcode";
diff --git a/pkgs/development/python-modules/raincloudy/default.nix b/pkgs/development/python-modules/raincloudy/default.nix
index 58973cc8a0a0..120ffc25b80f 100644
--- a/pkgs/development/python-modules/raincloudy/default.nix
+++ b/pkgs/development/python-modules/raincloudy/default.nix
@@ -10,7 +10,6 @@
   pytest-aiohttp,
   pytestCheckHook,
   pythonAtLeast,
-  pythonOlder,
   requests,
   requests-mock,
   setuptools,
@@ -25,7 +24,7 @@ buildPythonPackage rec {
   pypriject = true;
 
   # https://github.com/vanstinator/raincloudy/issues/65
-  disabled = pythonOlder "3.7" || pythonAtLeast "3.12";
+  disabled = pythonAtLeast "3.12";
 
   src = fetchFromGitHub {
     owner = "vanstinator";
diff --git a/pkgs/development/python-modules/sopel/default.nix b/pkgs/development/python-modules/sopel/default.nix
index f54e7bf9b29a..3b0165fed65a 100644
--- a/pkgs/development/python-modules/sopel/default.nix
+++ b/pkgs/development/python-modules/sopel/default.nix
@@ -10,7 +10,6 @@
   praw,
   pyenchant,
   pytestCheckHook,
-  pythonOlder,
   pytz,
   sqlalchemy,
   xmltodict,
@@ -23,7 +22,7 @@ buildPythonPackage rec {
   version = "8.0.4";
   pyproject = true;
 
-  disabled = isPyPy || pythonOlder "3.7";
+  disabled = isPyPy;
 
   src = fetchPypi {
     inherit pname version;
diff --git a/pkgs/development/python-modules/tzdata/default.nix b/pkgs/development/python-modules/tzdata/default.nix
index e489e3e4c41c..7989a6016e12 100644
--- a/pkgs/development/python-modules/tzdata/default.nix
+++ b/pkgs/development/python-modules/tzdata/default.nix
@@ -2,10 +2,8 @@
   lib,
   buildPythonPackage,
   fetchPypi,
-  importlib-resources,
   pytest-subtests,
   pytestCheckHook,
-  pythonOlder,
   setuptools,
 }:
 
@@ -24,8 +22,7 @@ buildPythonPackage rec {
   nativeCheckInputs = [
     pytestCheckHook
     pytest-subtests
-  ]
-  ++ lib.optionals (pythonOlder "3.7") [ importlib-resources ];
+  ];
 
   pythonImportsCheck = [ "tzdata" ];
 
diff --git a/pkgs/development/python-modules/zimports/default.nix b/pkgs/development/python-modules/zimports/default.nix
index 000338a49034..f76f386e6a0e 100644
--- a/pkgs/development/python-modules/zimports/default.nix
+++ b/pkgs/development/python-modules/zimports/default.nix
@@ -8,7 +8,6 @@
   setuptools,
   pytestCheckHook,
   pythonAtLeast,
-  pythonOlder,
 }:
 
 buildPythonPackage rec {
@@ -17,7 +16,7 @@ buildPythonPackage rec {
   format = "setuptools";
 
   # upstream technically support 3.7 through 3.9, but 3.10 happens to work while 3.11 breaks with an import error
-  disabled = pythonOlder "3.7" || pythonAtLeast "3.11";
+  disabled = pythonAtLeast "3.11";
 
   src = fetchFromGitHub {
     owner = "sqlalchemyorg";