diff --git a/pkgs/by-name/au/audacity/package.nix b/pkgs/by-name/au/audacity/package.nix
index 3f4110c6c7f7..919298baf10e 100644
--- a/pkgs/by-name/au/audacity/package.nix
+++ b/pkgs/by-name/au/audacity/package.nix
@@ -78,7 +78,7 @@ stdenv.mkDerivation (finalAttrs: {
   postPatch = ''
     mkdir src/private
     substituteInPlace scripts/build/macOS/fix_bundle.py \
-      --replace-fail "path.startswith('/usr/lib/')" "path.startswith('${builtins.storeDir}')"
+      --replace-fail "path.startswith('/usr/lib/')" "path.startswith('/usr/lib/') or path.startswith('${builtins.storeDir}')"
   ''
   + lib.optionalString stdenv.hostPlatform.isLinux ''
     substituteInPlace libraries/lib-files/FileNames.cpp \
diff --git a/pkgs/by-name/wx/wxGTK31/package.nix b/pkgs/by-name/wx/wxGTK31/package.nix
index e474550d6223..b9176a248730 100644
--- a/pkgs/by-name/wx/wxGTK31/package.nix
+++ b/pkgs/by-name/wx/wxGTK31/package.nix
@@ -80,6 +80,7 @@ stdenv.mkDerivation rec {
   ++ lib.optional withPrivateFonts "--enable-privatefonts"
   ++ lib.optional withMesa "--with-opengl"
   ++ lib.optionals stdenv.hostPlatform.isDarwin [
+    "--with-macosx-version-min=${stdenv.hostPlatform.darwinMinVersion}"
     "--with-osx_cocoa"
     "--with-libiconv"
   ]
diff --git a/pkgs/by-name/wx/wxGTK32/package.nix b/pkgs/by-name/wx/wxGTK32/package.nix
index 80a179152dfb..ef47cfef5bab 100644
--- a/pkgs/by-name/wx/wxGTK32/package.nix
+++ b/pkgs/by-name/wx/wxGTK32/package.nix
@@ -101,6 +101,7 @@ stdenv.mkDerivation rec {
   ++ lib.optional unicode "--enable-unicode"
   ++ lib.optional withMesa "--with-opengl"
   ++ lib.optionals stdenv.hostPlatform.isDarwin [
+    "--with-macosx-version-min=${stdenv.hostPlatform.darwinMinVersion}"
     "--with-osx_cocoa"
     "--with-libiconv"
     "--with-urlsession" # for wxWebRequest
diff --git a/pkgs/by-name/wx/wxwidgets_3_3/package.nix b/pkgs/by-name/wx/wxwidgets_3_3/package.nix
index 9f16a12edbb5..7a8236a7792f 100644
--- a/pkgs/by-name/wx/wxwidgets_3_3/package.nix
+++ b/pkgs/by-name/wx/wxwidgets_3_3/package.nix
@@ -86,6 +86,7 @@ stdenv.mkDerivation (finalAttrs: {
   ]
   ++ lib.optional withMesa "--with-opengl"
   ++ lib.optionals stdenv.hostPlatform.isDarwin [
+    "--with-macosx-version-min=${stdenv.hostPlatform.darwinMinVersion}"
     "--with-osx_cocoa"
     "--with-libiconv"
     "--with-urlsession" # for wxWebRequest