diff --git a/pkgs/applications/misc/plover/default.nix b/pkgs/applications/misc/plover/default.nix
index ac4811b30c41..68721c846f74 100644
--- a/pkgs/applications/misc/plover/default.nix
+++ b/pkgs/applications/misc/plover/default.nix
@@ -1,4 +1,4 @@
-{ lib, fetchurl, python27Packages, python36Packages, wmctrl,
+{ lib, fetchurl, python27Packages, python3Packages, wmctrl,
   qtbase, mkDerivationWith }:
 
 {
@@ -24,9 +24,9 @@
     ];
   };
 
-  dev = with python36Packages; mkDerivationWith buildPythonPackage rec {
+  dev = with python3Packages; mkDerivationWith buildPythonPackage rec {
     pname = "plover";
-    version = "4.0.0.dev8";
+    version = "4.0.0.dev10";
 
     meta = with lib; {
       description = "OpenSteno Plover stenography software";
@@ -36,7 +36,7 @@
 
     src = fetchurl {
       url    = "https://github.com/openstenoproject/plover/archive/v${version}.tar.gz";
-      sha256 = "1wxkmik1zyw5gqig5r0cas5v6f5408fbnximzw610rdisqy09rxp";
+      sha256 = "sha256-Eun+ZgmOIjYw6FS/2OGoBvYh52U/Ue0+NtIqrvV2Tqc=";
     };
 
     # I'm not sure why we don't find PyQt5 here but there's a similar
diff --git a/pkgs/applications/misc/variety/default.nix b/pkgs/applications/misc/variety/default.nix
index 9b40c4c44f1f..948719aae762 100644
--- a/pkgs/applications/misc/variety/default.nix
+++ b/pkgs/applications/misc/variety/default.nix
@@ -1,5 +1,5 @@
 { stdenv, lib, fetchFromGitHub
-, python37Packages
+, python3Packages
 , fehSupport ? false, feh
 , imagemagickSupport ? true, imagemagick
 , intltool
@@ -13,7 +13,7 @@
 , makeWrapper
 }:
 
-with python37Packages;
+with python3Packages;
 
 buildPythonApplication rec {
   pname = "variety";
diff --git a/pkgs/applications/networking/appgate-sdp/default.nix b/pkgs/applications/networking/appgate-sdp/default.nix
index e894572dd78c..397c64141ac9 100644
--- a/pkgs/applications/networking/appgate-sdp/default.nix
+++ b/pkgs/applications/networking/appgate-sdp/default.nix
@@ -32,8 +32,7 @@
 , openssl
 , pango
 , procps
-, python37
-, python37Packages
+, python3
 , stdenv
 , systemd
 , xdg-utils
@@ -101,8 +100,8 @@ stdenv.mkDerivation rec {
   dontBuild = true;
 
   buildInputs = [
-    python37
-    python37Packages.dbus-python
+    python3
+    python3.pkgs.dbus-python
   ];
 
   nativeBuildInputs = [
diff --git a/pkgs/applications/version-management/git-and-tools/bump2version/default.nix b/pkgs/applications/version-management/git-and-tools/bump2version/default.nix
index 47d31d6c18f6..ffb9455bd19f 100644
--- a/pkgs/applications/version-management/git-and-tools/bump2version/default.nix
+++ b/pkgs/applications/version-management/git-and-tools/bump2version/default.nix
@@ -1,22 +1,37 @@
-{ buildPythonApplication, fetchFromGitHub, isPy27, pytest, testfixtures, lib }:
+{ lib
+, buildPythonApplication
+, fetchFromGitHub
+, pytestCheckHook
+, pythonOlder
+, testfixtures
+}:
 
 buildPythonApplication rec {
   pname = "bump2version";
-  version = "1.0.0";
-  disabled = isPy27;
+  version = "1.0.1";
+
+  disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "c4urself";
     repo = pname;
-    rev = "refs/tags/v${version}";
-    sha256 = "10p7rg569rk3qvzs5kjj17894bqlsg3ihhbln6ciwwfhkfq1kpja";
+    rev = "v${version}";
+    sha256 = "sha256-j6HKi3jTwSgGBrA8PCJJNg+yQqRMo1aqaLgPGf4KAKU=";
   };
 
-  checkInputs = [ pytest testfixtures ];
-  # X's in pytest are git tests which won't run in sandbox
-  checkPhase = ''
-    pytest tests/ -k 'not usage_string_fork'
-  '';
+  checkInputs = [
+    pytestCheckHook
+    testfixtures
+  ];
+
+  disabledTests = [
+    # X's in pytest are git tests which won't run in sandbox
+    "usage_string_fork"
+    "test_usage_string"
+    "test_defaults_in_usage_with_config"
+  ];
+
+  pythonImportsCheck = [ "bumpversion" ];
 
   meta = with lib; {
     description = "Version-bump your software with a single command";
diff --git a/pkgs/development/embedded/platformio/chrootenv.nix b/pkgs/development/embedded/platformio/chrootenv.nix
index 72384c0994a2..138e7186624a 100644
--- a/pkgs/development/embedded/platformio/chrootenv.nix
+++ b/pkgs/development/embedded/platformio/chrootenv.nix
@@ -23,7 +23,8 @@ in buildFHSUserEnv {
   name = "platformio";
 
   targetPkgs = pio-pkgs;
-  multiPkgs = pio-pkgs;
+  # disabled temporarily because fastdiff no longer support 32bit
+  # multiPkgs = pio-pkgs;
 
   meta = with lib; {
     description = "An open source ecosystem for IoT development";
diff --git a/pkgs/development/embedded/platformio/core.nix b/pkgs/development/embedded/platformio/core.nix
index a3dcbdd35fdf..169ff4cd5a86 100644
--- a/pkgs/development/embedded/platformio/core.nix
+++ b/pkgs/development/embedded/platformio/core.nix
@@ -1,5 +1,6 @@
 { stdenv, lib, python3
 , fetchFromGitHub
+, fetchPypi
 , git
 , spdx-license-list-data
 , version, src
@@ -20,6 +21,15 @@ let
         doCheck = false;
       });
 
+      ajsonrpc = super.ajsonrpc.overridePythonAttrs (oldAttrs: rec {
+        pname = "ajsonrpc";
+        version = "1.1.0";
+        src = fetchPypi {
+          inherit pname version;
+          sha256 = "sha256-CgHCtW0gxZho7ZavvEaODNc+KbFW4sAsHtM2Xk5Cuaw=";
+        };
+      });
+
       click = super.click.overridePythonAttrs (oldAttrs: rec {
         version = "7.1.2";
         src = oldAttrs.src.override {
@@ -28,6 +38,18 @@ let
         };
       });
 
+      starlette = super.starlette.overridePythonAttrs (oldAttrs: rec {
+        pname = "starlette";
+        version = "0.14.2";
+        src = fetchFromGitHub {
+          owner = "encode";
+          repo = pname;
+          rev = version;
+          sha256 = "sha256-Ki5jTEr5w6CrGK6F60E9uvdUlGx8pxdHMpxHvj9D4js=";
+        };
+        doCheck = false;
+      });
+
       uvicorn = super.uvicorn.overridePythonAttrs (oldAttrs: rec {
         version = "0.13.2";
         src = fetchFromGitHub {
diff --git a/pkgs/development/libraries/boxfort/default.nix b/pkgs/development/libraries/boxfort/default.nix
index 740e43216984..93176fb230f1 100644
--- a/pkgs/development/libraries/boxfort/default.nix
+++ b/pkgs/development/libraries/boxfort/default.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, fetchFromGitHub, meson, ninja, python37Packages }:
+{ lib, stdenv, fetchFromGitHub, meson, ninja, python3Packages }:
 
 stdenv.mkDerivation rec {
   version = "unstable-2019-10-09";
@@ -17,7 +17,7 @@ stdenv.mkDerivation rec {
     patchShebangs ci/isdir.py
   '';
 
-  checkInputs = with python37Packages; [ cram ];
+  checkInputs = with python3Packages; [ cram ];
 
   doCheck = true;
 
diff --git a/pkgs/development/libraries/criterion/default.nix b/pkgs/development/libraries/criterion/default.nix
index ba436fec0a26..a1e7137d92ab 100644
--- a/pkgs/development/libraries/criterion/default.nix
+++ b/pkgs/development/libraries/criterion/default.nix
@@ -1,5 +1,5 @@
 { lib, stdenv, fetchFromGitHub, boxfort, cmake, libcsptr, pkg-config, gettext
-, dyncall , nanomsg, python37Packages }:
+, dyncall , nanomsg, python3Packages }:
 
 stdenv.mkDerivation rec {
   version = "2.3.3";
@@ -23,7 +23,7 @@ stdenv.mkDerivation rec {
     nanomsg
   ];
 
-  checkInputs = with python37Packages; [ cram ];
+  checkInputs = with python3Packages; [ cram ];
 
   cmakeFlags = [ "-DCTESTS=ON" ];
   doCheck = true;
diff --git a/pkgs/development/libraries/science/math/caffe2/default.nix b/pkgs/development/libraries/science/math/caffe2/default.nix
index fe9a8b671459..202903b9aa18 100644
--- a/pkgs/development/libraries/science/math/caffe2/default.nix
+++ b/pkgs/development/libraries/science/math/caffe2/default.nix
@@ -139,5 +139,9 @@ stdenv.mkDerivation rec {
     platforms = with lib.platforms; linux;
     license = lib.licenses.asl20;
     maintainers = with lib.maintainers; [ yuriaisaka ];
+    # fails to compile with
+    # error: invalid conversion from 'const char*' to 'char*'
+    # TODO: Remove usage of python2, protobuf overwrite
+    broken = true;
   };
 }
diff --git a/pkgs/development/python-modules/Cython/default.nix b/pkgs/development/python-modules/Cython/default.nix
index dcede9506e32..e22037cbbb9f 100644
--- a/pkgs/development/python-modules/Cython/default.nix
+++ b/pkgs/development/python-modules/Cython/default.nix
@@ -12,8 +12,7 @@
 }:
 
 let
-  excludedTests = []
-    ++ [ "reimport_from_subinterpreter" ]
+  excludedTests = [ "reimport_from_subinterpreter" ]
     # cython's testsuite is not working very well with libc++
     # We are however optimistic about things outside of testsuite still working
     ++ lib.optionals (stdenv.cc.isClang or false) [ "cpdef_extern_func" "libcpp_algo" ]
@@ -26,19 +25,21 @@ let
 
 in buildPythonPackage rec {
   pname = "Cython";
-  version = "0.29.22";
+  version = "0.29.24";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-32uDx6bR2WfqiaKQPkqTE3djSil0WWUuRVFzTEgZVAY=";
+    sha256 = "sha256-zfBNB8NgCGDowuuq1Oj1KsP+shJFPBdkpJrAjIJ+hEM=";
   };
 
   nativeBuildInputs = [
     pkg-config
   ];
+
   checkInputs = [
     gdb numpy ncurses
   ];
+
   buildInputs = [ glibcLocales ];
   LC_ALL = "en_US.UTF-8";
 
@@ -71,9 +72,7 @@ in buildPythonPackage rec {
   # https://github.com/cython/cython/issues/2785
   # Temporary solution
   doCheck = false;
-
-#   doCheck = !stdenv.isDarwin;
-
+  # doCheck = !stdenv.isDarwin;
 
   meta = {
     description = "An optimising static compiler for both the Python programming language and the extended Cython programming language";
diff --git a/pkgs/development/python-modules/Fabric/default.nix b/pkgs/development/python-modules/Fabric/default.nix
index 2e70d3aa121e..de53512d0b47 100644
--- a/pkgs/development/python-modules/Fabric/default.nix
+++ b/pkgs/development/python-modules/Fabric/default.nix
@@ -1,9 +1,11 @@
-{ lib, buildPythonPackage, fetchPypi
+{ lib
+, buildPythonPackage
+, fetchPypi
 , cryptography
 , invoke
 , mock
 , paramiko
-, pytest
+, pytestCheckHook
 , pytest-relaxed
 }:
 
@@ -23,20 +25,21 @@ buildPythonPackage rec {
   '';
 
   propagatedBuildInputs = [ invoke paramiko cryptography ];
-  checkInputs = [ pytest mock pytest-relaxed ];
 
-  # requires pytest_relaxed, which doesnt have official support for pytest>=5
-  # https://github.com/bitprophet/pytest-relaxed/issues/12
+  checkInputs = [ pytestCheckHook pytest-relaxed mock ];
+
+  # ==================================== ERRORS ====================================
+  # ________________________ ERROR collecting test session _________________________
+  # Direct construction of SpecModule has been deprecated, please use SpecModule.from_parent
+  # See https://docs.pytest.org/en/stable/deprecations.html#node-construction-changed-to-node-from-parent for more details.
   doCheck = false;
-  checkPhase = ''
-    pytest tests
-  '';
+
   pythonImportsCheck = [ "fabric" ];
 
   meta = with lib; {
     description = "Pythonic remote execution";
-    homepage    = "https://www.fabfile.org/";
-    license     = licenses.bsd2;
+    homepage = "https://www.fabfile.org/";
+    license = licenses.bsd2;
     maintainers = [ maintainers.costrouc ];
   };
 }
diff --git a/pkgs/development/python-modules/Mako/default.nix b/pkgs/development/python-modules/Mako/default.nix
index 533e1317a091..cf3028612698 100644
--- a/pkgs/development/python-modules/Mako/default.nix
+++ b/pkgs/development/python-modules/Mako/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "Mako";
-  version = "1.1.4";
+  version = "1.1.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "17831f0b7087c313c0ffae2bcbbd3c1d5ba9eeac9c38f2eb7b50e8c99fe9d5ab";
+    sha256 = "169fa52af22a91900d852e937400e79f535496191c63712e3b9fda5a9bed6fc3";
   };
 
   propagatedBuildInputs = [ markupsafe ];
diff --git a/pkgs/development/python-modules/Pygments/default.nix b/pkgs/development/python-modules/Pygments/default.nix
index 640c95bfcf9f..bb17af144cbe 100644
--- a/pkgs/development/python-modules/Pygments/default.nix
+++ b/pkgs/development/python-modules/Pygments/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "Pygments";
-  version = "2.9.0";
+  version = "2.10.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a18f47b506a429f6f4b9df81bb02beab9ca21d0a5fee38ed15aef65f0545519f";
+    sha256 = "f398865f7eb6874156579fdf36bc840a03cab64d1cde9e93d68f46a425ec52c6";
   };
 
   propagatedBuildInputs = [ docutils ];
diff --git a/pkgs/development/python-modules/ROPGadget/default.nix b/pkgs/development/python-modules/ROPGadget/default.nix
index 8c34e75139f6..6be0ed48e289 100644
--- a/pkgs/development/python-modules/ROPGadget/default.nix
+++ b/pkgs/development/python-modules/ROPGadget/default.nix
@@ -3,11 +3,11 @@
 
 buildPythonPackage rec {
   pname = "ROPGadget";
-  version = "6.5";
+  version = "6.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "4c0e56f2ba0aef13b2c8ca286aad663525b92020b11bacd16791f5236247905c";
+    sha256 = "dc61186e0114ec67ec7ce374df8fd2ddc2a7cba129a1242338e900a7483fba22";
   };
 
   propagatedBuildInputs = [ capstone ];
diff --git a/pkgs/development/python-modules/acme-tiny/default.nix b/pkgs/development/python-modules/acme-tiny/default.nix
index 76e8a8401fd4..dcbb9a688f57 100644
--- a/pkgs/development/python-modules/acme-tiny/default.nix
+++ b/pkgs/development/python-modules/acme-tiny/default.nix
@@ -1,27 +1,35 @@
-{ lib, buildPythonPackage, fetchPypi, setuptools-scm, fusepy, fuse
-, openssl }:
+{ lib
+, buildPythonPackage
+, fetchPypi
+, setuptools-scm
+, fusepy
+, fuse
+, openssl
+}:
 
 buildPythonPackage rec {
   pname = "acme-tiny";
-  version = "4.1.0";
+  version = "4.1.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0jmg525n4n98hwy3hf303jbnq23z79sqwgliji9j7qcnph47gkgq";
+    sha256 = "b7050b9428d45319e14ab9ea77f0ff4eb40451e5a68325d4c5358a87cff0e793";
   };
 
   patchPhase = ''
     substituteInPlace acme_tiny.py --replace '"openssl"' '"${openssl.bin}/bin/openssl"'
-    substituteInPlace tests/monkey.py --replace '"openssl"' '"${openssl.bin}/bin/openssl"'
     substituteInPlace tests/test_module.py --replace '"openssl"' '"${openssl.bin}/bin/openssl"'
-    substituteInPlace tests/monkey.py --replace /etc/ssl/openssl.cnf ${openssl.out}/etc/ssl/openssl.cnf
+    substituteInPlace tests/utils.py --replace /etc/ssl/openssl.cnf ${openssl.out}/etc/ssl/openssl.cnf
   '';
 
   buildInputs = [ setuptools-scm ];
+
   checkInputs = [ fusepy fuse ];
 
   doCheck = false; # seems to hang, not sure
 
+  pythonImportsCheck = [ "acme_tiny" ];
+
   meta = with lib; {
     description = "A tiny script to issue and renew TLS certs from Let's Encrypt";
     homepage = "https://github.com/diafygi/acme-tiny";
diff --git a/pkgs/development/python-modules/acoustics/default.nix b/pkgs/development/python-modules/acoustics/default.nix
index 9047910a2138..e888d1241a50 100644
--- a/pkgs/development/python-modules/acoustics/default.nix
+++ b/pkgs/development/python-modules/acoustics/default.nix
@@ -1,32 +1,57 @@
-{ lib, buildPythonPackage, fetchPypi
-, pytest, numpy, scipy, matplotlib, pandas, tabulate, pythonOlder }:
+{ lib
+, buildPythonPackage
+, fetchPypi
+, matplotlib
+, numpy
+, pandas
+, pytestCheckHook
+, pythonOlder
+, scipy
+, tabulate
+}:
 
 buildPythonPackage rec {
   pname = "acoustics";
   version = "0.2.4.post0";
 
-  checkInputs = [ pytest ];
-  propagatedBuildInputs = [ numpy scipy matplotlib pandas tabulate ];
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
     sha256 = "a162625e5e70ed830fab8fab0ddcfe35333cb390cd24b0a827bcefc5bbcae97d";
   };
 
-  checkPhase = ''
+  propagatedBuildInputs = [
+    matplotlib
+    numpy
+    pandas
+    scipy
+    tabulate
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  preCheck = ''
     export HOME=$TMPDIR
     mkdir -p $HOME/.matplotlib
     echo "backend: ps" > $HOME/.matplotlib/matplotlibrc
-
-    pushd tests
-    py.test -Wignore::DeprecationWarning ./.
-    popd
   '';
 
-  disabled = pythonOlder "3.6";
+  pytestFlagsArray = [
+    "-Wignore::DeprecationWarning"
+  ];
+
+  disabledTestPaths = [
+    # All tests fail with TypeError
+    "tests/test_aio.py"
+  ];
+
+  pythonImportsCheck = [ "acoustics" ];
 
   meta = with lib; {
-    description = "A package for acousticians";
+    description = "Python package for acousticians";
     maintainers = with maintainers; [ fridh ];
     license = with licenses; [ bsd3 ];
     homepage = "https://github.com/python-acoustics/python-acoustics";
diff --git a/pkgs/development/python-modules/agate-excel/default.nix b/pkgs/development/python-modules/agate-excel/default.nix
index 752c905ee8e6..cbf49d8477c3 100644
--- a/pkgs/development/python-modules/agate-excel/default.nix
+++ b/pkgs/development/python-modules/agate-excel/default.nix
@@ -4,11 +4,11 @@
 
 buildPythonPackage rec {
   pname = "agate-excel";
-  version = "0.2.3";
+  version = "0.2.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8f255ef2c87c436b7132049e1dd86c8e08bf82d8c773aea86f3069b461a17d52";
+    sha256 = "62315708433108772f7f610ca769996b468a4ead380076dbaf6ffe262831b153";
   };
 
   propagatedBuildInputs = [ agate openpyxl xlrd ];
diff --git a/pkgs/development/python-modules/aiobotocore/default.nix b/pkgs/development/python-modules/aiobotocore/default.nix
index e07b56d3f266..591fd8c17874 100644
--- a/pkgs/development/python-modules/aiobotocore/default.nix
+++ b/pkgs/development/python-modules/aiobotocore/default.nix
@@ -10,12 +10,12 @@
 
 buildPythonPackage rec {
   pname = "aiobotocore";
-  version = "1.3.1";
+  version = "1.4.1";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8ecee55346651e0f4cbda883e3e16cfe11460b8d7adcc08d0017cbb867636ae1";
+    sha256 = "09f06723d1d69c6d407d9a356ca65ab42a5b7b73a45be4b1ed0ed1a6b6057a9f";
   };
 
   # relax version constraints: aiobotocore works with newer botocore versions
diff --git a/pkgs/development/python-modules/aioprocessing/default.nix b/pkgs/development/python-modules/aioprocessing/default.nix
index 2f6b39678489..a4571a79b05d 100644
--- a/pkgs/development/python-modules/aioprocessing/default.nix
+++ b/pkgs/development/python-modules/aioprocessing/default.nix
@@ -7,7 +7,7 @@
 buildPythonPackage rec {
   pname = "aioprocessing";
   version = "2.0.0";
-  disabled = pythonOlder "3.4";
+  disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
diff --git a/pkgs/development/python-modules/aioredis/default.nix b/pkgs/development/python-modules/aioredis/default.nix
index fe48ba0e1e18..807b112772cf 100644
--- a/pkgs/development/python-modules/aioredis/default.nix
+++ b/pkgs/development/python-modules/aioredis/default.nix
@@ -1,20 +1,27 @@
-{ lib, buildPythonPackage, fetchPypi
-, pkgs, async-timeout, hiredis, isPyPy, isPy27
+{ lib
+, buildPythonPackage
+, fetchPypi
+, async-timeout
+, typing-extensions
+, hiredis
+, isPyPy
+, pythonOlder
 }:
 
 buildPythonPackage rec {
   pname = "aioredis";
-  version = "1.3.1";
+  version = "2.0.0";
 
-  disabled = isPy27;
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0fi7jd5hlx8cnv1m97kv9hc4ih4l8v15wzkqwsp73is4n0qazy0m";
+    sha256 = "3a2de4b614e6a5f8e104238924294dc4e811aefbe17ddf52c04a93cbf06e67db";
   };
 
   propagatedBuildInputs = [
     async-timeout
+    typing-extensions
   ] ++ lib.optional (!isPyPy) hiredis;
 
   # Wants to run redis-server, hardcoded FHS paths, too much trouble.
diff --git a/pkgs/development/python-modules/ajsonrpc/default.nix b/pkgs/development/python-modules/ajsonrpc/default.nix
index e5a81d9cfa6e..b3482cd74679 100644
--- a/pkgs/development/python-modules/ajsonrpc/default.nix
+++ b/pkgs/development/python-modules/ajsonrpc/default.nix
@@ -2,13 +2,13 @@
 
 buildPythonPackage rec {
   pname = "ajsonrpc";
-  version = "1.1.0";
+  version = "1.2.0";
 
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1b5r8975wdnk3qnc1qjnn4lkxmqcir3brbwnxml9ii90dnsw408a";
+    sha256 = "791bac18f0bf0dee109194644f151cf8b7ff529c4b8d6239ac48104a3251a19f";
   };
 
   checkInputs = [ pytestCheckHook ];
diff --git a/pkgs/development/python-modules/alembic/default.nix b/pkgs/development/python-modules/alembic/default.nix
index 9c7244b3c066..af8b1fc37215 100644
--- a/pkgs/development/python-modules/alembic/default.nix
+++ b/pkgs/development/python-modules/alembic/default.nix
@@ -1,26 +1,56 @@
-{ lib, buildPythonPackage, fetchPypi
-, pytest, pytest-cov, mock, coverage, setuptools
-, Mako, sqlalchemy, python-editor, python-dateutil
+{ lib
+, buildPythonPackage
+, fetchPypi
+, pythonOlder
+, Mako
+, python-dateutil
+, sqlalchemy
+, importlib-metadata
+, importlib-resources
+, pytest-xdist
+, pytestCheckHook
+
 }:
 
 buildPythonPackage rec {
   pname = "alembic";
-  version = "1.6.5";
+  version = "1.7.1";
+  format = "setuptools";
+
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a21fedebb3fb8f6bbbba51a11114f08c78709377051384c9c5ead5705ee93a51";
+    sha256 = "aea964d3dcc9c205b8759e4e9c1c3935ea3afeee259bffd7ed8414f8085140fb";
   };
 
-  buildInputs = [ pytest pytest-cov mock coverage ];
-  propagatedBuildInputs = [ Mako sqlalchemy python-editor python-dateutil setuptools ];
+  propagatedBuildInputs = [
+    Mako
+    python-dateutil
+    sqlalchemy
+  ] ++ lib.optionals (pythonOlder "3.9") [
+    importlib-resources
+  ] ++ lib.optionals (pythonOlder "3.8") [
+    importlib-metadata
+  ];
 
-  # no traditional test suite
-  doCheck = false;
+  pythonImportsCheck = [
+    "alembic"
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+    pytest-xdist
+  ];
+
+  pytestFlagsArray = [
+    "--numprocesses" "auto"
+  ];
 
   meta = with lib; {
     homepage = "https://bitbucket.org/zzzeek/alembic";
     description = "A database migration tool for SQLAlchemy";
     license = licenses.mit;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/ansi2html/default.nix b/pkgs/development/python-modules/ansi2html/default.nix
index 4abcec541a04..50188fe0e4a3 100644
--- a/pkgs/development/python-modules/ansi2html/default.nix
+++ b/pkgs/development/python-modules/ansi2html/default.nix
@@ -1,4 +1,4 @@
-{ lib, buildPythonPackage, fetchPypi, isPy3k, six, mock, pytestCheckHook, setuptools, setuptools-scm, toml }:
+{ lib, buildPythonPackage, fetchPypi, isPy3k, six, mock, pytestCheckHook, setuptools, setuptools-scm }:
 
 buildPythonPackage rec {
   pname = "ansi2html";
@@ -11,7 +11,7 @@ buildPythonPackage rec {
     sha256 = "0f124ea7efcf3f24f1f9398e527e688c9ae6eab26b0b84e1299ef7f94d92c596";
   };
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
   propagatedBuildInputs = [ six setuptools ];
 
   preCheck = "export PATH=$PATH:$out/bin";
diff --git a/pkgs/development/python-modules/ansible-runner/default.nix b/pkgs/development/python-modules/ansible-runner/default.nix
index ba11ef11e3b8..9dc8eadb7775 100644
--- a/pkgs/development/python-modules/ansible-runner/default.nix
+++ b/pkgs/development/python-modules/ansible-runner/default.nix
@@ -14,11 +14,11 @@
 
 buildPythonPackage rec {
   pname = "ansible-runner";
-  version = "1.4.7";
+  version = "2.0.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1bb56f9061c3238d89ec8871bc842f5b8d0e868f892347e8455c98d5b6fa58a1";
+    sha256 = "c02b690803ec0be4453411c53743cd3fdca1dfc66dfa075794e14e717c5b61b3";
   };
 
   checkInputs = [ pytest mock ];
diff --git a/pkgs/development/python-modules/apispec/default.nix b/pkgs/development/python-modules/apispec/default.nix
index 2753864fed81..c5777d7c5173 100644
--- a/pkgs/development/python-modules/apispec/default.nix
+++ b/pkgs/development/python-modules/apispec/default.nix
@@ -12,12 +12,12 @@
 
 buildPythonPackage rec {
   pname = "apispec";
-  version = "4.7.1";
+  version = "5.1.0";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1yf71c9nq1rfb5pkgmfw486fvywi1bjnmgwxcly7y3basf3980kr";
+    sha256 = "9ac7a7a6000339a02d05404ef561e013375f170de01d8b238782f8fb83082b5b";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/arrow/default.nix b/pkgs/development/python-modules/arrow/default.nix
index d47dd61c3d47..956dd5f40f2d 100644
--- a/pkgs/development/python-modules/arrow/default.nix
+++ b/pkgs/development/python-modules/arrow/default.nix
@@ -12,13 +12,13 @@
 
 buildPythonPackage rec {
   pname = "arrow";
-  version = "1.1.0";
+  version = "1.1.1";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1n2vzyrirfj7fp0zn6iipm3i8bch0g4m14z02nrvlyjiyfmi7zmq";
+    sha256 = "dee7602f6c60e3ec510095b5e301441bc56288cb8f51def14dcb3079f623823a";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/asn1/default.nix b/pkgs/development/python-modules/asn1/default.nix
new file mode 100644
index 000000000000..7a83703f862c
--- /dev/null
+++ b/pkgs/development/python-modules/asn1/default.nix
@@ -0,0 +1,45 @@
+{ lib
+, buildPythonPackage
+, pythonOlder
+, fetchFromGitHub
+, future
+, pytestCheckHook
+}:
+
+buildPythonPackage rec {
+  pname = "asn1";
+  version = "2.4.1";
+
+  disabled = pythonOlder "3.7";
+
+  src = fetchFromGitHub {
+    owner = "andrivet";
+    repo = "python-asn1";
+    rev = "v${version}";
+    sha256 = "0g2d5cr1pxsm5ackba7padf7gvlgrgv807kh0312s5axjd2cww2l";
+  };
+
+  propagatedBuildInputs = [
+    future
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "enum-compat" ""
+  '';
+
+  pytestFlagsArray = [ "tests/test_asn1.py" ];
+
+  pythonImportsCheck = [ "asn1" ];
+
+  meta = with lib; {
+    description = "Python ASN.1 encoder and decoder";
+    homepage = "https://github.com/andrivet/python-asn1";
+    license = licenses.mit;
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/development/python-modules/astroid/default.nix b/pkgs/development/python-modules/astroid/default.nix
index 59bd0bc7c369..a4694663bb6b 100644
--- a/pkgs/development/python-modules/astroid/default.nix
+++ b/pkgs/development/python-modules/astroid/default.nix
@@ -13,7 +13,7 @@
 
 buildPythonPackage rec {
   pname = "astroid";
-  version = "2.5.6"; # Check whether the version is compatible with pylint
+  version = "2.7.3"; # Check whether the version is compatible with pylint
 
   disabled = pythonOlder "3.6";
 
@@ -21,7 +21,7 @@ buildPythonPackage rec {
     owner = "PyCQA";
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-/nWXzuWkerUDvFT/tJTZuhfju46MAM0cwosVH9BXoY8=";
+    sha256 = "08qxw58cdyglkni6ahyil4cmnb48zz0wr4v05gzqk4r5ifs4gl2m";
   };
 
   SETUPTOOLS_SCM_PRETEND_VERSION=version;
diff --git a/pkgs/development/python-modules/asttokens/default.nix b/pkgs/development/python-modules/asttokens/default.nix
index bb4cf989cddf..251205419fe4 100644
--- a/pkgs/development/python-modules/asttokens/default.nix
+++ b/pkgs/development/python-modules/asttokens/default.nix
@@ -1,29 +1,35 @@
-{ lib, fetchPypi, fetchpatch, buildPythonPackage,
-  setuptools-scm, toml, six, astroid, pytest
+{ lib
+, fetchPypi
+, buildPythonPackage
+, setuptools-scm
+, six
+, astroid
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "asttokens";
-  version = "2.0.4";
+  version = "2.0.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0a2ixiz04aw4p0aivxh47k3fa9ql804l3y5iv5gcih9aizi5fbm4";
+    sha256 = "sha256-mlTBFPAsepSA1WVQkyVGo/H+cdigLxvHzNDuPuNc9NU=";
   };
 
-  patches = [
-    # Fixes compatibility with python 3.9, will be included in the next release
-    # after 2.0.4
-    (fetchpatch {
-      url = "https://github.com/gristlabs/asttokens/commit/d8ff80ee7d2e64c5e1daf50cc38eb99663f1b1ac.patch";
-      sha256 = "19y8n8vpzr2ijldbq5rh19sf0vz5azqqpkb9bx0ljjg98h6k7kjj";
-      excludes = [ "setup.cfg" ];
-    })
+  nativeBuildInputs = [
+    setuptools-scm
   ];
 
-  propagatedBuildInputs = [ setuptools-scm toml six astroid ];
+  propagatedBuildInputs = [
+    six
+    astroid
+  ];
 
-  checkInputs = [ pytest ];
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  pythonImportsCheck = [ "asttokens" ];
 
   meta = with lib; {
     homepage = "https://github.com/gristlabs/asttokens";
diff --git a/pkgs/development/python-modules/auth0-python/default.nix b/pkgs/development/python-modules/auth0-python/default.nix
index 67701afc0eb0..6d47f95e7564 100644
--- a/pkgs/development/python-modules/auth0-python/default.nix
+++ b/pkgs/development/python-modules/auth0-python/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "auth0-python";
-  version = "3.16.2";
+  version = "3.17.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-Slpwml1GDdxAZ4P6Vn2brrupRofiOHvmQF26l0gtTJM=";
+    sha256 = "7b21bf91859ea56ac3b665efe5e73340c65dfd30de01081ff334a18a35a188a6";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/authcaptureproxy/default.nix b/pkgs/development/python-modules/authcaptureproxy/default.nix
index a780ae59be70..c03b423932df 100644
--- a/pkgs/development/python-modules/authcaptureproxy/default.nix
+++ b/pkgs/development/python-modules/authcaptureproxy/default.nix
@@ -15,14 +15,14 @@
 
 buildPythonPackage rec {
   pname = "authcaptureproxy";
-  version = "1.0.1";
+  version = "1.0.2";
   format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "alandtse";
     repo = "auth_capture_proxy";
     rev = "v${version}";
-    sha256 = "1fbrmh6qa3dm3q3zdxaa0fls94wardbcvnjgwxk686wpjgs1xrs4";
+    sha256 = "1cg63qhf823nf785kyl96r7vyxfl6dlbwsmhcpny8vb65pl9gng5";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/awscrt/default.nix b/pkgs/development/python-modules/awscrt/default.nix
index 08e0563b966b..fa29e9f636e3 100644
--- a/pkgs/development/python-modules/awscrt/default.nix
+++ b/pkgs/development/python-modules/awscrt/default.nix
@@ -2,7 +2,7 @@
 
 buildPythonPackage rec {
   pname = "awscrt";
-  version = "0.11.24";
+  version = "0.12.0";
 
   buildInputs = lib.optionals stdenv.isDarwin
     (with darwin.apple_sdk.frameworks; [ CoreFoundation Security ]);
@@ -23,7 +23,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b8aa68bca404bf0085be0570eff5b542d01f7e8e3c0f9b0859abfe5e070162ff";
+    sha256 = "65fa09ce78902319392bbb62991ddd3b33cebc0e3bbc81ad2c176072ab40de52";
   };
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/azure-core/default.nix b/pkgs/development/python-modules/azure-core/default.nix
index 8dce5b8feb75..cd0a816815cd 100644
--- a/pkgs/development/python-modules/azure-core/default.nix
+++ b/pkgs/development/python-modules/azure-core/default.nix
@@ -15,14 +15,14 @@
 }:
 
 buildPythonPackage rec {
-  version = "1.16.0";
+  version = "1.17.0";
   pname = "azure-core";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
     extension = "zip";
-    sha256 = "b1c7d2e01846074f258c8b2e592239aef836a2b1c27d8d0e8491a2c7e2906ef4";
+    sha256 = "25407390dde142d3e41ecf78bb18cedda9b7f7a0af558d082dec711c4a334f46";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/azure-mgmt-iothubprovisioningservices/default.nix b/pkgs/development/python-modules/azure-mgmt-iothubprovisioningservices/default.nix
index 3401ed898c8f..fe1d5096cd34 100644
--- a/pkgs/development/python-modules/azure-mgmt-iothubprovisioningservices/default.nix
+++ b/pkgs/development/python-modules/azure-mgmt-iothubprovisioningservices/default.nix
@@ -6,23 +6,25 @@
 , msrest
 , msrestazure
 , azure-common
+, azure-mgmt-core
 , azure-mgmt-nspkg
 }:
 
 buildPythonPackage rec {
   pname = "azure-mgmt-iothubprovisioningservices";
-  version = "0.2.0";
+  version = "1.0.0";
 
   src = fetchPypi {
     inherit pname version;
     extension = "zip";
-    sha256 = "8c37acfd1c33aba845f2e0302ef7266cad31cba503cc990a48684659acb7b91d";
+    sha256 = "e5871b03488b5ae6dfc441cdbda40cb39c000635ee57c513053792b3c15826a9";
   };
 
   propagatedBuildInputs = [
     msrest
     msrestazure
     azure-common
+    azure-mgmt-core
     azure-mgmt-nspkg
   ];
 
diff --git a/pkgs/development/python-modules/azure-mgmt-kusto/azure-mgmt-apimanagement/default.nix b/pkgs/development/python-modules/azure-mgmt-kusto/azure-mgmt-apimanagement/default.nix
index 6cf775c2118e..4c7233203bb9 100644
--- a/pkgs/development/python-modules/azure-mgmt-kusto/azure-mgmt-apimanagement/default.nix
+++ b/pkgs/development/python-modules/azure-mgmt-kusto/azure-mgmt-apimanagement/default.nix
@@ -5,13 +5,13 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.3.0";
+  version = "2.1.0";
   pname = "azure-mgmt-apimanagement";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ec363581ef950945447e45d259441cb690a4b790057c7b8470ad8a6eeca04feb";
+    sha256 = "58296bd45e876df33f93f3a41c866c36476f5f3bd46818e8891308794f041c94";
     extension = "zip";
   };
 
diff --git a/pkgs/development/python-modules/azure-mgmt-recoveryservices/default.nix b/pkgs/development/python-modules/azure-mgmt-recoveryservices/default.nix
index d1f49355f8b9..29b0dd2eb1ca 100644
--- a/pkgs/development/python-modules/azure-mgmt-recoveryservices/default.nix
+++ b/pkgs/development/python-modules/azure-mgmt-recoveryservices/default.nix
@@ -11,12 +11,12 @@
 
 buildPythonPackage rec {
   pname = "azure-mgmt-recoveryservices";
-  version = "1.0.0";
+  version = "2.0.0";
 
   src = fetchPypi {
     inherit pname version;
     extension = "zip";
-    sha256 = "ab87108c0d5ce27d80583b4bfad966ad07049dcbc0e9ac28c64aa6bbdae64e22";
+    sha256 = "a7d3137d5c460f50ac2d44061d60a70b4f2779d4ca844b77419b5725e65e09be";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/backports-entry-points-selectable/default.nix b/pkgs/development/python-modules/backports-entry-points-selectable/default.nix
new file mode 100644
index 000000000000..2c1fa41f469b
--- /dev/null
+++ b/pkgs/development/python-modules/backports-entry-points-selectable/default.nix
@@ -0,0 +1,30 @@
+{ lib, buildPythonPackage, fetchPypi, pythonOlder, setuptools-scm, importlib-metadata }:
+
+buildPythonPackage rec {
+  pname = "backports-entry-points-selectable";
+  version = "1.1.0";
+
+  src = fetchPypi {
+    pname = "backports.entry_points_selectable";
+    inherit version;
+    sha256 = "988468260ec1c196dab6ae1149260e2f5472c9110334e5d51adcb77867361f6a";
+  };
+
+  nativeBuildInputs = [ setuptools-scm ];
+
+  propagatedBuildInputs = lib.optionals (pythonOlder "3.8") [
+    importlib-metadata
+  ];
+
+  # no tests
+  doCheck = false;
+
+  pythonImportsCheck = [ "backports.entry_points_selectable" ];
+
+  meta = with lib; {
+    description = "Compatibility shim providing selectable entry points for older implementations";
+    homepage = "https://github.com/jaraco/backports.entry_points_selectable";
+    license = licenses.mit;
+    maintainers = with maintainers; [ SuperSandro2000 ];
+  };
+}
diff --git a/pkgs/development/python-modules/bellows/default.nix b/pkgs/development/python-modules/bellows/default.nix
index e52e07627dbb..a95bf6054fd8 100644
--- a/pkgs/development/python-modules/bellows/default.nix
+++ b/pkgs/development/python-modules/bellows/default.nix
@@ -46,10 +46,9 @@ buildPythonPackage rec {
   ];
 
   disabledTests = [
-    # RuntimeError: coroutine 'test_remigrate_forcibly_downgraded_v4' was never awaited
-    #"test_remigrate_forcibly_downgraded_v4"
-    # RuntimeError: Event loop is closed
-    "test_thread_already_stopped"
+    # AssertionError: assert 65534 is None
+    # https://github.com/zigpy/bellows/issues/436
+    "test_startup_nwk_params"
   ];
 
   pythonImportsCheck = [
diff --git a/pkgs/development/python-modules/beniget/default.nix b/pkgs/development/python-modules/beniget/default.nix
index f8733eeed626..51f641c51eb4 100644
--- a/pkgs/development/python-modules/beniget/default.nix
+++ b/pkgs/development/python-modules/beniget/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "beniget";
-  version = "0.4.0";
+  version = "0.4.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "72bbd47b1ae93690f5fb2ad3902ce1ae61dcd868ce6cfbf33e9bad71f9ed8749";
+    sha256 = "75554b3b8ad0553ce2f607627dad3d95c60c441189875b98e097528f8e23ac0c";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/block-io/default.nix b/pkgs/development/python-modules/block-io/default.nix
index b823b8711a53..a76132e3e211 100644
--- a/pkgs/development/python-modules/block-io/default.nix
+++ b/pkgs/development/python-modules/block-io/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "block-io";
-  version = "1.1.15";
+  version = "2.0.4";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "97ea037a67af72037cb08cec7e0a9f7866ecdfaa1a8c8ebcc0f4b9359a1516d7";
+    sha256 = "817c9cd2ff76659caca4bb3d6758d5782a85f8c0ea13b08c4e14f0c2a8b7586d";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/bokeh/default.nix b/pkgs/development/python-modules/bokeh/default.nix
index 6677d9ceacb9..925eb9c8f39d 100644
--- a/pkgs/development/python-modules/bokeh/default.nix
+++ b/pkgs/development/python-modules/bokeh/default.nix
@@ -34,11 +34,11 @@
 buildPythonPackage rec {
   pname = "bokeh";
   # update together with panel which is not straightforward
-  version = "2.3.2";
+  version = "2.3.3";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fcc0d0a3129ae457cdb0a4f503843a4d13d1f5d07af7748424ea8c7ddfc321f1";
+    sha256 = "a5fdcc181835561447fcc5a371300973fce4114692d5853addec284d1cdeb677";
   };
 
   patches = [
diff --git a/pkgs/development/python-modules/boto3/default.nix b/pkgs/development/python-modules/boto3/default.nix
index c8b8210f6503..07a79a6a886b 100644
--- a/pkgs/development/python-modules/boto3/default.nix
+++ b/pkgs/development/python-modules/boto3/default.nix
@@ -13,11 +13,11 @@
 
 buildPythonPackage rec {
   pname = "boto3";
-  version = "1.17.97"; # N.B: if you change this, change botocore and awscli to a matching version
+  version = "1.17.106"; # N.B: if you change this, change botocore and awscli to a matching version
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0ab5afc51461c30f27aebef944211d16f47697b98ff8d2e2f6e49e59584853bb";
+    sha256 = "sha256-wHQDeLkTylP1/A26kemadSxaMK57WKDF5U4+KmjfJsU=";
   };
 
   propagatedBuildInputs = [ botocore jmespath s3transfer ] ++ lib.optionals (!isPy3k) [ futures ];
diff --git a/pkgs/development/python-modules/botocore/default.nix b/pkgs/development/python-modules/botocore/default.nix
index d05c2decf497..fc275edcc9de 100644
--- a/pkgs/development/python-modules/botocore/default.nix
+++ b/pkgs/development/python-modules/botocore/default.nix
@@ -13,11 +13,11 @@
 
 buildPythonPackage rec {
   pname = "botocore";
-  version = "1.20.97"; # N.B: if you change this, change boto3 and awscli to a matching version
+  version = "1.20.106"; # N.B: if you change this, change boto3 and awscli to a matching version
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f7e119cf3e0f4a36100f0e983583afa91a84fb27c479a1716820aee4f2e190ab";
+    sha256 = "sha256-bVyYOAix0AQ39W0MCEEr2C2fgBL9t35VX5cneh/U1d8=";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/braintree/default.nix b/pkgs/development/python-modules/braintree/default.nix
index 6d64def54ab6..17681f053337 100644
--- a/pkgs/development/python-modules/braintree/default.nix
+++ b/pkgs/development/python-modules/braintree/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "braintree";
-  version = "4.10.0";
+  version = "4.12.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f934a329c7a2b3f7058d5c733cc95da694f66afb5a789162ec701ba4d26a0d90";
+    sha256 = "946abd50fe2843eec586ac3cec285d27dfae0cc5a43a64b505e8a2800b8a74a6";
   };
 
   propagatedBuildInputs = [ requests ];
diff --git a/pkgs/development/python-modules/brotli/default.nix b/pkgs/development/python-modules/brotli/default.nix
index 1edc62317a64..0556c5b4e2a2 100644
--- a/pkgs/development/python-modules/brotli/default.nix
+++ b/pkgs/development/python-modules/brotli/default.nix
@@ -1,4 +1,7 @@
-{ lib, buildPythonPackage, fetchFromGitHub, pytest }:
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pytestCheckHook }:
 
 buildPythonPackage rec {
   pname = "brotli";
@@ -16,15 +19,18 @@ buildPythonPackage rec {
 
   dontConfigure = true;
 
-  checkInputs = [ pytest ];
+  checkInputs = [
+    pytestCheckHook
+  ];
 
-  checkPhase = ''
-    pytest python/tests
-  '';
+  pytestFlagsArray = [
+    "python/tests"
+  ];
 
-  meta = {
+  meta = with lib; {
     homepage = "https://github.com/google/brotli";
     description = "Generic-purpose lossless compression algorithm";
-    license = lib.licenses.mit;
+    license = licenses.mit;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/canonicaljson/default.nix b/pkgs/development/python-modules/canonicaljson/default.nix
index 4a4f56f5abf5..ca64d599534e 100644
--- a/pkgs/development/python-modules/canonicaljson/default.nix
+++ b/pkgs/development/python-modules/canonicaljson/default.nix
@@ -1,5 +1,11 @@
-{ lib, buildPythonPackage, fetchPypi
-, frozendict, simplejson, six, isPy27
+{ lib
+, buildPythonPackage
+, fetchPypi
+, frozendict
+, simplejson
+, six
+, isPy27
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
@@ -13,7 +19,15 @@ buildPythonPackage rec {
   };
 
   propagatedBuildInputs = [
-    frozendict simplejson six
+    frozendict
+    simplejson
+    six
+  ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  disabledTests = [
+    "test_frozen_dict"
   ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/casbin/default.nix b/pkgs/development/python-modules/casbin/default.nix
index 3f2b26e9c5f9..47a6a48eaca7 100644
--- a/pkgs/development/python-modules/casbin/default.nix
+++ b/pkgs/development/python-modules/casbin/default.nix
@@ -8,7 +8,7 @@
 
 buildPythonPackage rec {
   pname = "casbin";
-  version = "0.20.0";
+  version = "1.7.0";
 
   disabled = isPy27;
 
@@ -16,7 +16,7 @@ buildPythonPackage rec {
     owner = pname;
     repo = "pycasbin";
     rev = "v${version}";
-    sha256 = "1j7kd4rvf4myg4x4sm4njlhzkxm2m3cva9wmp9vx0nnpfdlyb67f";
+    sha256 = "1qwns8ph8w5bb26hzkk1dadm2bjq74g65wm6g971llb5jdq9a8z9";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/cffi/default.nix b/pkgs/development/python-modules/cffi/default.nix
index 92899ed85e58..94aecdcc4ec4 100644
--- a/pkgs/development/python-modules/cffi/default.nix
+++ b/pkgs/development/python-modules/cffi/default.nix
@@ -2,11 +2,11 @@
 
 if isPyPy then null else buildPythonPackage rec {
   pname = "cffi";
-  version = "1.14.5";
+  version = "1.14.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fd78e5fee591709f32ef6edb9a015b4aa1a5022598e36227500c8f4e02328d9c";
+    sha256 = "c9a875ce9d7fe32887784274dd533c57909b7b1dcadcc128a2ac21331a9765dd";
   };
 
   outputs = [ "out" "dev" ];
diff --git a/pkgs/development/python-modules/cfn-lint/default.nix b/pkgs/development/python-modules/cfn-lint/default.nix
index d8e0af78e1cd..6f6d55502958 100644
--- a/pkgs/development/python-modules/cfn-lint/default.nix
+++ b/pkgs/development/python-modules/cfn-lint/default.nix
@@ -21,13 +21,13 @@
 
 buildPythonPackage rec {
   pname = "cfn-lint";
-  version = "0.53.0";
+  version = "0.53.1";
 
   src = fetchFromGitHub {
     owner = "aws-cloudformation";
     repo = "cfn-python-lint";
     rev = "v${version}";
-    sha256 = "sha256-UHcbbBoByoxW7+AUxu5mQmcvC3irHPQvBv4CbBXPTNo=";
+    sha256 = "1wj2pzrrmrdf3mkhnz1qx41rshvfpgwlrxrb80d63r098pnq6df8";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/chart-studio/default.nix b/pkgs/development/python-modules/chart-studio/default.nix
index e059725cad24..9d8c6ecb84d5 100644
--- a/pkgs/development/python-modules/chart-studio/default.nix
+++ b/pkgs/development/python-modules/chart-studio/default.nix
@@ -10,14 +10,14 @@
 
 buildPythonPackage rec {
   pname = "chart-studio";
-  version = "4.14.3";
+  version = "5.3.0";
 
   # chart-studio was split from plotly
   src = fetchFromGitHub {
     owner = "plotly";
     repo = "plotly.py";
     rev = "v${version}";
-    sha256 = "1yrrcn9032r3l8y2cc1wvpydg4rkqvgkpyv1s7znby5mrxa1rjma";
+    sha256 = "059rq278r5zb2sngby7jzh8kd9c48sd82b6b7s5bbrmzj42sds3n";
   };
 
   sourceRoot = "source/packages/python/chart-studio";
diff --git a/pkgs/development/python-modules/cliff/default.nix b/pkgs/development/python-modules/cliff/default.nix
index bb856736d92b..7eee574dad48 100644
--- a/pkgs/development/python-modules/cliff/default.nix
+++ b/pkgs/development/python-modules/cliff/default.nix
@@ -16,11 +16,11 @@
 
 buildPythonPackage rec {
   pname = "cliff";
-  version = "3.8.0";
+  version = "3.9.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8dd215d0a84c9a3ab2fa2aa700849f4e7b786639f66caa0ad4108c85dca95a7c";
+    sha256 = "95363e9b43e2ec9599e33b5aea27a6953beda2d0673557916fa4f5796857daa3";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/cmd2/default.nix b/pkgs/development/python-modules/cmd2/default.nix
index b5bbc88c341f..7d979d1f0216 100644
--- a/pkgs/development/python-modules/cmd2/default.nix
+++ b/pkgs/development/python-modules/cmd2/default.nix
@@ -1,21 +1,58 @@
-{ lib, stdenv, fetchPypi, buildPythonPackage, pythonOlder, isPy3k
-, pyperclip, six, pyparsing, vim, wcwidth, colorama, attrs
-, contextlib2 ? null, typing ? null, setuptools-scm
-, pytest, mock ? null, pytest-mock
-, which, glibcLocales
+{ lib
+, stdenv
+, attrs
+, buildPythonPackage
+, colorama
+, fetchPypi
+, glibcLocales
+, importlib-metadata
+, pyperclip
+, pytest-mock
+, pytestCheckHook
+, pythonOlder
+, setuptools-scm
+, typing-extensions
+, vim
+, wcwidth
 }:
+
 buildPythonPackage rec {
   pname = "cmd2";
-  version = "1.5.0";
+  version = "2.1.2";
+
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "701a8c9975c4abc45e5d13906ab149f959f812869106347323a3f89ac0e82a62";
+    sha256 = "25dbb2e9847aaa686a8a21e84e3d101db8b79f5cb992e044fc54210ab8c0ad41";
   };
 
-  LC_ALL="en_US.UTF-8";
+  LC_ALL = "en_US.UTF-8";
 
-  postPatch = lib.optionalString stdenv.isDarwin ''
+  buildInputs = [
+    setuptools-scm
+  ];
+
+  propagatedBuildInputs = [
+    attrs
+    colorama
+    pyperclip
+    wcwidth
+  ] ++ lib.optionals (pythonOlder "3.8") [
+    typing-extensions
+    importlib-metadata
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+    glibcLocales
+    pytest-mock
+    vim
+  ];
+
+  postPatch = ''
+    sed -i "/--cov/d" setup.cfg
+  '' + lib.optionalString stdenv.isDarwin ''
     # Fake the impure dependencies pbpaste and pbcopy
     mkdir bin
     echo '#!${stdenv.shell}' > bin/pbpaste
@@ -24,33 +61,9 @@ buildPythonPackage rec {
     export PATH=$(realpath bin):$PATH
   '';
 
-  disabled = !isPy3k;
-
-  buildInputs = [
-    setuptools-scm
-  ];
-
-  propagatedBuildInputs = [
-    colorama
-    pyperclip
-    six
-    pyparsing
-    wcwidth
-    attrs
-  ]
-  ++ lib.optionals (pythonOlder "3.5") [contextlib2 typing]
-  ;
-
-
   doCheck = !stdenv.isDarwin;
-  # pytest-cov
-  # argcomplete  will generate errors
-  checkInputs= [ pytest mock which vim glibcLocales pytest-mock ]
-        ++ lib.optional (pythonOlder "3.6") [ mock ];
-  checkPhase = ''
-    # test_path_completion_user_expansion might be fixed in the next release
-    py.test -k 'not test_path_completion_user_expansion'
-  '';
+
+  pythonImportsCheck = [ "cmd2" ];
 
   meta = with lib; {
     description = "Enhancements for standard library's cmd module";
diff --git a/pkgs/development/python-modules/colorlog/default.nix b/pkgs/development/python-modules/colorlog/default.nix
index 39b64e4faf3e..6abb6ff023ad 100644
--- a/pkgs/development/python-modules/colorlog/default.nix
+++ b/pkgs/development/python-modules/colorlog/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "colorlog";
-  version = "5.0.1";
+  version = "6.4.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-8XwBOgaWKwL0RJ7gfP2+ayh98p78LJoVFbSjdvTliOo=";
+    sha256 = "af99440154a01f27c09256760ea3477982bf782721feaa345904e806879df4d8";
   };
 
   checkInputs = [ pytestCheckHook ];
diff --git a/pkgs/development/python-modules/commoncode/default.nix b/pkgs/development/python-modules/commoncode/default.nix
index 16d529b17f53..e7dfb65e7946 100644
--- a/pkgs/development/python-modules/commoncode/default.nix
+++ b/pkgs/development/python-modules/commoncode/default.nix
@@ -14,11 +14,11 @@
 }:
 buildPythonPackage rec {
   pname = "commoncode";
-  version = "21.6.11";
+  version = "21.8.27";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "d6c8c985746a541913d5bb534c770f2422e5b4ac7a4ef765abc05c287a40ff4b";
+    sha256 = "789ee1798cd74ab4516d2e547473d69717d3b2ed7ee180ab2746e0bdfd0d88a4";
   };
 
   dontConfigure = true;
diff --git a/pkgs/development/python-modules/configargparse/default.nix b/pkgs/development/python-modules/configargparse/default.nix
index 45ec7364a59a..1bb036b97df5 100644
--- a/pkgs/development/python-modules/configargparse/default.nix
+++ b/pkgs/development/python-modules/configargparse/default.nix
@@ -7,13 +7,13 @@
 
 buildPythonPackage rec {
   pname = "configargparse";
-  version = "1.4.1";
+  version = "1.5.2";
 
   src = fetchFromGitHub {
     owner = "bw2";
     repo = "ConfigArgParse";
-    rev = "v${version}";
-    sha256 = "sha256-hzhjrdrXxjksvbHlTnQVsT350g0yuG1F21fElv6bLSA=";
+    rev = version;
+    sha256 = "1hgd0gfxycfnlddwsr8sl6ybxzp8rqhin16vphbl8q32wp5hhjd2";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/configparser/default.nix b/pkgs/development/python-modules/configparser/default.nix
index a939f6623c9c..3eeae353d115 100644
--- a/pkgs/development/python-modules/configparser/default.nix
+++ b/pkgs/development/python-modules/configparser/default.nix
@@ -1,6 +1,4 @@
-{ lib, stdenv, buildPythonPackage, fetchPypi, setuptools-scm
-, toml
-}:
+{ lib, stdenv, buildPythonPackage, fetchPypi, setuptools-scm }:
 
 buildPythonPackage rec {
   pname = "configparser";
@@ -14,7 +12,7 @@ buildPythonPackage rec {
   # No tests available
   doCheck = false;
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
 
   preConfigure = ''
     export LC_ALL=${if stdenv.isDarwin then "en_US" else "C"}.UTF-8
diff --git a/pkgs/development/python-modules/contextlib2/0.nix b/pkgs/development/python-modules/contextlib2/0.nix
new file mode 100644
index 000000000000..38d9fb696e28
--- /dev/null
+++ b/pkgs/development/python-modules/contextlib2/0.nix
@@ -0,0 +1,23 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, unittest2
+}:
+
+buildPythonPackage rec {
+  pname = "contextlib2";
+  version = "0.6.0.post1";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "01f490098c18b19d2bd5bb5dc445b2054d2fa97f09a4280ba2c5f3c394c8162e";
+  };
+
+  checkInputs = [ unittest2 ];
+
+  meta = {
+    description = "Backports and enhancements for the contextlib module";
+    homepage = "https://contextlib2.readthedocs.org/";
+    license = lib.licenses.psfl;
+  };
+}
diff --git a/pkgs/development/python-modules/contextlib2/default.nix b/pkgs/development/python-modules/contextlib2/default.nix
index 38d9fb696e28..1387e786e7b7 100644
--- a/pkgs/development/python-modules/contextlib2/default.nix
+++ b/pkgs/development/python-modules/contextlib2/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "contextlib2";
-  version = "0.6.0.post1";
+  version = "21.6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "01f490098c18b19d2bd5bb5dc445b2054d2fa97f09a4280ba2c5f3c394c8162e";
+    sha256 = "ab1e2bfe1d01d968e1b7e8d9023bc51ef3509bba217bb730cee3827e1ee82869";
   };
 
   checkInputs = [ unittest2 ];
diff --git a/pkgs/development/python-modules/cryptacular/default.nix b/pkgs/development/python-modules/cryptacular/default.nix
index dccfddaea1ae..31c0ebace475 100644
--- a/pkgs/development/python-modules/cryptacular/default.nix
+++ b/pkgs/development/python-modules/cryptacular/default.nix
@@ -3,11 +3,11 @@
 
 buildPythonPackage rec {
   pname = "cryptacular";
-  version = "1.5.5";
+  version = "1.6.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fb4d48716e88e4d050255ff0f065f6d437caa358ceef16ba5840c95cece224f9";
+    sha256 = "7b529cb2b8a3c7e5be77921bf1ebc653d4d3a8f791375cc6f971b20db2404176";
   };
 
   buildInputs = [ coverage nose ];
diff --git a/pkgs/development/python-modules/cupy/default.nix b/pkgs/development/python-modules/cupy/default.nix
index 6a072ab8e1a7..c165c9af7a20 100644
--- a/pkgs/development/python-modules/cupy/default.nix
+++ b/pkgs/development/python-modules/cupy/default.nix
@@ -7,12 +7,12 @@
 
 buildPythonPackage rec {
   pname = "cupy";
-  version = "8.6.0";
+  version = "9.4.0";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f3ed02ba18e38b4f3ed2c324fa08967e6714f59357ccb0b28badd9572e77500b";
+    sha256 = "4402bd33a051e82f6888dab088a8d657714ca6d1e945b513dcc513a95a435bd5";
   };
 
   preConfigure = ''
diff --git a/pkgs/development/python-modules/cx_freeze/default.nix b/pkgs/development/python-modules/cx_freeze/default.nix
index b6edb2ced1f2..42fa8fd8ddca 100644
--- a/pkgs/development/python-modules/cx_freeze/default.nix
+++ b/pkgs/development/python-modules/cx_freeze/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "cx_Freeze";
-  version = "6.6";
+  version = "6.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c4af8ad3f7e7d71e291c1dec5d0fb26bbe92df834b098ed35434c901fbd6762f";
+    sha256 = "050f1dd133a04810bd7f38ac7ae3b290054acb2ff4f6e73f7a286266d153495d";
   };
 
   disabled = pythonOlder "3.5";
diff --git a/pkgs/development/python-modules/cxxfilt/default.nix b/pkgs/development/python-modules/cxxfilt/default.nix
index 1cc5ad19bda2..117b12145764 100644
--- a/pkgs/development/python-modules/cxxfilt/default.nix
+++ b/pkgs/development/python-modules/cxxfilt/default.nix
@@ -6,11 +6,11 @@
 }:
 buildPythonPackage rec {
   pname = "cxxfilt";
-  version = "0.2.2";
+  version = "0.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ef6810e76d16c95c11b96371e2d8eefd1d270ec03f9bcd07590e8dcc2c69e92b";
+    sha256 = "7df6464ba5e8efbf0d8974c0b2c78b32546676f06059a83515dbdfa559b34214";
   };
 
   postPatch = let
diff --git a/pkgs/development/python-modules/dask-jobqueue/default.nix b/pkgs/development/python-modules/dask-jobqueue/default.nix
index 7719842fbad6..5e43a8f16648 100644
--- a/pkgs/development/python-modules/dask-jobqueue/default.nix
+++ b/pkgs/development/python-modules/dask-jobqueue/default.nix
@@ -8,12 +8,12 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.7.2";
+  version = "0.7.3";
   pname = "dask-jobqueue";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1767f4146b2663d9d2eaef62b882a86e1df0bccdb8ae68ae3e5e546aa6796d35";
+    sha256 = "682d7cc0e6b319b6ab83a7a898680c12e9c77ddc77df380b40041290f55d4e79";
   };
 
   checkInputs = [ pytest ];
diff --git a/pkgs/development/python-modules/dask-xgboost/default.nix b/pkgs/development/python-modules/dask-xgboost/default.nix
index eb18ac31fd03..1f9be870c975 100644
--- a/pkgs/development/python-modules/dask-xgboost/default.nix
+++ b/pkgs/development/python-modules/dask-xgboost/default.nix
@@ -7,12 +7,12 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.1.11";
+  version = "0.2.0";
   pname = "dask-xgboost";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3fbe1bf4344dc74edfbe9f928c7e3e6acc26dc57cefd8da8ae56a15469c6941c";
+    sha256 = "6d9c491dc4099f74a0df66c4d439d296c0f1fba97009fe93e21b2350f295b4ca";
   };
 
   propagatedBuildInputs = [ xgboost dask distributed ];
diff --git a/pkgs/development/python-modules/dask/default.nix b/pkgs/development/python-modules/dask/default.nix
index 208856490b86..120c98febce2 100644
--- a/pkgs/development/python-modules/dask/default.nix
+++ b/pkgs/development/python-modules/dask/default.nix
@@ -2,44 +2,51 @@
 , stdenv
 , bokeh
 , buildPythonPackage
+, cloudpickle
+, distributed
 , fetchFromGitHub
 , fsspec
-, pytestCheckHook
-, pytest-rerunfailures
-, pythonOlder
-, cloudpickle
+, jinja2
 , numpy
-, toolz
-, dill
+, packaging
 , pandas
 , partd
+, pytest-rerunfailures
 , pytest-xdist
+, pytestCheckHook
+, pythonOlder
+, pyyaml
+, toolz
 , withExtraComplete ? false
-, distributed
 }:
 
 buildPythonPackage rec {
   pname = "dask";
-  version = "2021.06.2";
-  disabled = pythonOlder "3.5";
+  version = "2021.08.1";
+  format = "setuptools";
+
+  disabled = pythonOlder "3.7";
 
   src = fetchFromGitHub {
     owner = "dask";
     repo = pname;
     rev = version;
-    sha256 = "sha256-qvfjdijzlqaJQrDztRAVr5PudTaVd3WOTBid2ElZQgg=";
+    sha256 = "sha256-HnrHOp3Y/iLYaK3KVp6NJrK68BMqX8lTl/wLosiGc7k=";
   };
 
   propagatedBuildInputs = [
-    bokeh
     cloudpickle
-    dill
     fsspec
-    numpy
-    pandas
+    packaging
     partd
+    pyyaml
     toolz
-  ] ++ lib.optionals withExtraComplete [
+    pandas
+    jinja2
+    bokeh
+    numpy
+  ] ++ lib.optionals (withExtraComplete) [
+    # infinite recursion between distributed and dask
     distributed
   ];
 
@@ -63,7 +70,11 @@ buildPythonPackage rec {
   '';
 
   pytestFlagsArray = [
-    "-n $NIX_BUILD_CORES"
+    # parallelize
+    "--numprocesses auto"
+    # rerun failed tests up to three times
+    "--reruns 3"
+    # don't run tests that require network access
     "-m 'not network'"
   ];
 
@@ -81,7 +92,16 @@ buildPythonPackage rec {
 
   __darwinAllowLocalNetworking = true;
 
-  pythonImportsCheck = [ "dask.dataframe" "dask" "dask.array" ];
+  pythonImportsCheck = [
+    "dask"
+    "dask.array"
+    "dask.bag"
+    "dask.bytes"
+    "dask.dataframe"
+    "dask.dataframe.io"
+    "dask.dataframe.tseries"
+    "dask.diagnostics"
+  ];
 
   meta = with lib; {
     description = "Minimal task scheduling abstraction";
diff --git a/pkgs/development/python-modules/dateutils/default.nix b/pkgs/development/python-modules/dateutils/default.nix
new file mode 100644
index 000000000000..faa3b1155483
--- /dev/null
+++ b/pkgs/development/python-modules/dateutils/default.nix
@@ -0,0 +1,25 @@
+{ lib, buildPythonPackage, fetchPypi, python-dateutil, pytz }:
+
+buildPythonPackage rec {
+  pname = "dateutils";
+  version = "0.6.12";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "sha256-A92QvLIVQb1OtLATY35PG1+USIHEbMbktnpgWeNw4/E=";
+  };
+
+  propagatedBuildInputs = [
+    python-dateutil
+    pytz
+  ];
+
+  pythonImportsCheck = [ "dateutils" ];
+
+  meta = with lib; {
+    description = "Utilities for working with datetime objects.";
+    homepage = "https://github.com/jmcantrell/python-dateutils";
+    license = licenses.bsd0;
+    maintainers = with maintainers; [ SuperSandro2000 ];
+  };
+}
diff --git a/pkgs/development/python-modules/debugpy/default.nix b/pkgs/development/python-modules/debugpy/default.nix
index 35ac416d5992..0bdfe35514d4 100644
--- a/pkgs/development/python-modules/debugpy/default.nix
+++ b/pkgs/development/python-modules/debugpy/default.nix
@@ -62,7 +62,7 @@ buildPythonPackage rec {
       "x86_64-darwin"  = "-std=c++11 -lc -D_REENTRANT -dynamiclib -arch x86_64 -o attach_x86_64.dylib";
       "i686-darwin"    = "-std=c++11 -lc -D_REENTRANT -dynamiclib -arch i386 -o attach_x86.dylib";
       "aarch64-darwin" = "-std=c++11 -lc -D_REENTRANT -dynamiclib -arch arm64 -o attach_arm64.dylib";
-    }.${stdenv.hostPlatform.system}}
+    }.${stdenv.hostPlatform.system} or (throw "Unsupported system: ${stdenv.hostPlatform.system}")}
   )'';
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/decorator/4.nix b/pkgs/development/python-modules/decorator/4.nix
new file mode 100644
index 000000000000..8e8fd28f0b54
--- /dev/null
+++ b/pkgs/development/python-modules/decorator/4.nix
@@ -0,0 +1,21 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+}:
+
+buildPythonPackage rec {
+  pname = "decorator";
+  version = "4.4.2";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "1rxzhk5zwiggk45hl53zydvy70lk654kg0nc1p54090p402jz9p3";
+  };
+
+  meta = with lib; {
+    homepage = "https://pypi.python.org/pypi/decorator";
+    description = "Better living through Python with decorators";
+    license = lib.licenses.mit;
+    maintainers = [ maintainers.costrouc ];
+  };
+}
diff --git a/pkgs/development/python-modules/decorator/default.nix b/pkgs/development/python-modules/decorator/default.nix
index 8e8fd28f0b54..f8d3f5c9ac61 100644
--- a/pkgs/development/python-modules/decorator/default.nix
+++ b/pkgs/development/python-modules/decorator/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "decorator";
-  version = "4.4.2";
+  version = "5.0.9";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1rxzhk5zwiggk45hl53zydvy70lk654kg0nc1p54090p402jz9p3";
+    sha256 = "72ecfba4320a893c53f9706bebb2d55c270c1e51a28789361aa93e4a21319ed5";
   };
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/distributed/default.nix b/pkgs/development/python-modules/distributed/default.nix
index ce0cf13e9a92..38c977f3ffa5 100644
--- a/pkgs/development/python-modules/distributed/default.nix
+++ b/pkgs/development/python-modules/distributed/default.nix
@@ -19,13 +19,13 @@
 
 buildPythonPackage rec {
   pname = "distributed";
-  version = "2021.6.2";
+  version = "2021.8.1";
   disabled = pythonOlder "3.6";
 
   # get full repository need conftest.py to run tests
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-19ESqGqwSdzvo7If0brqQhKiwD0iwkvVWtONIaf10Ug=";
+    sha256 = "c13ac10ecd9ee5f0ff67f5697149062d6e483f23a079918df1ab2e19b11fa77d";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/distro/default.nix b/pkgs/development/python-modules/distro/default.nix
index 885538de65ce..bf8675af941d 100644
--- a/pkgs/development/python-modules/distro/default.nix
+++ b/pkgs/development/python-modules/distro/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "distro";
-  version = "1.5.0";
+  version = "1.6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0e58756ae38fbd8fc3020d54badb8eae17c5b9dcbed388b17bb55b8a5928df92";
+    sha256 = "83f5e5a09f9c5f68f60173de572930effbcc0287bb84fdc4426cb4168c088424";
   };
 
   # tests are very targeted at individual linux distributions
diff --git a/pkgs/development/python-modules/django-cacheops/default.nix b/pkgs/development/python-modules/django-cacheops/default.nix
index c9344d3bd010..58900ac2cbf4 100644
--- a/pkgs/development/python-modules/django-cacheops/default.nix
+++ b/pkgs/development/python-modules/django-cacheops/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "django-cacheops";
-  version = "5.1";
+  version = "6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-1YUc178whzhKH87PqN3bj1UDDu39b98SciW3W8oPmd0=";
+    sha256 = "78e161ebd96a32e28e19ec7da31f2afed9e62a79726b8b5f0ed12dd16c2e5841";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/django_environ/default.nix b/pkgs/development/python-modules/django_environ/default.nix
index 3f01a2b294a1..6baaf58e7d09 100644
--- a/pkgs/development/python-modules/django_environ/default.nix
+++ b/pkgs/development/python-modules/django_environ/default.nix
@@ -7,11 +7,11 @@
 
 buildPythonPackage rec {
   pname = "django-environ";
-  version = "0.4.5";
+  version = "0.5.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "6c9d87660142608f63ec7d5ce5564c49b603ea8ff25da595fd6098f6dc82afde";
+    sha256 = "a8726675c1ebefa4706b36398c4d3c5c790d335ffe55c4a10378f6bfd57ad8d0";
   };
 
   # The testsuite fails to modify the base environment
diff --git a/pkgs/development/python-modules/django_taggit/default.nix b/pkgs/development/python-modules/django_taggit/default.nix
index cbfcc103c5c1..ab908c639a00 100644
--- a/pkgs/development/python-modules/django_taggit/default.nix
+++ b/pkgs/development/python-modules/django_taggit/default.nix
@@ -11,12 +11,12 @@
 
 buildPythonPackage rec {
   pname = "django-taggit";
-  version = "1.4.0";
+  version = "1.5.1";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b9ed6e94bad0bed3bf062a6be7ee3db117fda02c6419c680d614197364ea018b";
+    sha256 = "e5bb62891f458d55332e36a32e19c08d20142c43f74bc5656c803f8af25c084a";
   };
 
   propagatedBuildInputs = [ isort django ];
diff --git a/pkgs/development/python-modules/djangorestframework-simplejwt/default.nix b/pkgs/development/python-modules/djangorestframework-simplejwt/default.nix
index 82ff51fd3821..ad9afabadf2c 100644
--- a/pkgs/development/python-modules/djangorestframework-simplejwt/default.nix
+++ b/pkgs/development/python-modules/djangorestframework-simplejwt/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "djangorestframework_simplejwt";
-  version = "4.7.1";
+  version = "4.8.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c0e9b617da337becb55e67935eb992fad84f861418e7ab5fb3e77a3fd18d4137";
+    sha256 = "153c973c5c154baf566be431de8527c2bd62557fde7373ebcb0f02b73b28e07a";
   };
 
   propagatedBuildInputs = [ django djangorestframework pyjwt ];
diff --git a/pkgs/development/python-modules/dpkt/default.nix b/pkgs/development/python-modules/dpkt/default.nix
index 74817e60cbcf..a1036e099ea8 100644
--- a/pkgs/development/python-modules/dpkt/default.nix
+++ b/pkgs/development/python-modules/dpkt/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "dpkt";
-  version = "1.9.7.1";
+  version = "1.9.7.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "74899d557ec4e337db29cecc80548b23a1205384d30ee407397cfb9ab178e3d4";
+    sha256 = "80f977667ebbad2b5c4f7b7f45ee8bea6622fb71723f68a9a8fe6274520c853b";
   };
 
   # Project has no tests
diff --git a/pkgs/development/python-modules/elmax/default.nix b/pkgs/development/python-modules/elmax/default.nix
index 775050acb0c9..db1ff91ee0eb 100644
--- a/pkgs/development/python-modules/elmax/default.nix
+++ b/pkgs/development/python-modules/elmax/default.nix
@@ -12,7 +12,7 @@
 
 buildPythonPackage rec {
   pname = "elmax";
-  version = "0.1.2";
+  version = "0.1.3";
   format = "pyproject";
   disabled = pythonOlder "3.7";
 
@@ -20,7 +20,7 @@ buildPythonPackage rec {
     owner = "home-assistant-ecosystem";
     repo = "python-elmax";
     rev = version;
-    sha256 = "sha256-Aq/OHxOmtUUmBNlFPu892C8AkTX+Ee0oca7D79InPXQ=";
+    sha256 = "sha256-OiVPjWqQw1u0OL6/uYlT+FP2XDh7l3OZyVtQfycHICI=";
   };
 
   nativeBuildInputs = [ poetry-core ];
diff --git a/pkgs/development/python-modules/executing/default.nix b/pkgs/development/python-modules/executing/default.nix
index f0c67f3ae591..8ab6994ac415 100644
--- a/pkgs/development/python-modules/executing/default.nix
+++ b/pkgs/development/python-modules/executing/default.nix
@@ -1,6 +1,7 @@
 { lib
 , buildPythonPackage
 , fetchFromGitHub
+, setuptools-scm
 , asttokens
 }:
 
@@ -15,6 +16,10 @@ buildPythonPackage rec {
     sha256 = "1hqx94h6l2wg9sljiaajfay2nr62sqa819w3bxrz8cdki1abdygv";
   };
 
+  nativeBuildInputs = [
+    setuptools-scm
+  ];
+
   preBuild = ''
     export SETUPTOOLS_SCM_PRETEND_VERSION="${version}"
   '';
diff --git a/pkgs/development/python-modules/extractcode/default.nix b/pkgs/development/python-modules/extractcode/default.nix
index 28dece127b12..a39205f5aeea 100644
--- a/pkgs/development/python-modules/extractcode/default.nix
+++ b/pkgs/development/python-modules/extractcode/default.nix
@@ -11,11 +11,11 @@
 }:
 buildPythonPackage rec {
   pname = "extractcode";
-  version = "21.6.2";
+  version = "21.7.23";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e665501438fedeb6e75335d880c8913a8cd894fd8adcf9c243eb6d48fad2d01c";
+    sha256 = "58aa16d60cfcbd3695d7ea84a1e30d5ba9fa6f614b2ef4a6d0565b2ac5d4f757";
   };
 
   dontConfigure = true;
diff --git a/pkgs/development/python-modules/fakeredis/default.nix b/pkgs/development/python-modules/fakeredis/default.nix
index 2e0e5c65d06b..e76eb8903d60 100644
--- a/pkgs/development/python-modules/fakeredis/default.nix
+++ b/pkgs/development/python-modules/fakeredis/default.nix
@@ -21,7 +21,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-Ecz8l2nXGNN+RbOC5kproCWGtiKvoDcaa9hXZtciVfM=";
+    sha256 = "11ccfc9769d718d37e45b382e64a6ba02586b622afa0371a6bd85766d72255f3";
   };
 
   propagatedBuildInputs = [
@@ -41,8 +41,8 @@ buildPythonPackage rec {
   ];
 
   disabledTestPaths = [
-    # Missing support for later pytest-asyncio, https://github.com/jamesls/fakeredis/issues/307
-    "test/test_aioredis1.py"
+    # AttributeError: 'AsyncGenerator' object has no attribute XXXX
+    "test/test_aioredis2.py"
   ];
 
   pythonImportsCheck = [ "fakeredis" ];
diff --git a/pkgs/development/python-modules/fastapi/default.nix b/pkgs/development/python-modules/fastapi/default.nix
index 62aedf1f2117..f068c4cb735e 100644
--- a/pkgs/development/python-modules/fastapi/default.nix
+++ b/pkgs/development/python-modules/fastapi/default.nix
@@ -55,8 +55,18 @@ buildPythonPackage rec {
   # ignoring deprecation warnings to avoid test failure from
   # tests/test_tutorial/test_testing/test_tutorial001.py
 
-  pytestFlagsArray = [ "--ignore=tests/test_default_response_class.py" "-W ignore::DeprecationWarning"];
-  disabledTests = [ "test_get_custom_response" ];
+  pytestFlagsArray = [
+    "--ignore=tests/test_default_response_class.py"
+    "-W ignore::DeprecationWarning"
+  ];
+
+  disabledTests = [
+    "test_get_custom_response"
+
+    # Failed: DID NOT RAISE <class 'starlette.websockets.WebSocketDisconnect'>
+    "test_websocket_invalid_data"
+    "test_websocket_no_credentials"
+  ];
 
   meta = with lib; {
     homepage = "https://github.com/tiangolo/fastapi";
diff --git a/pkgs/development/python-modules/fastdiff/default.nix b/pkgs/development/python-modules/fastdiff/default.nix
index b3e27d7a5e81..a790f1623817 100644
--- a/pkgs/development/python-modules/fastdiff/default.nix
+++ b/pkgs/development/python-modules/fastdiff/default.nix
@@ -1,30 +1,33 @@
-{ lib, buildPythonPackage, fetchPypi, pytestCheckHook, pytest-benchmark, wasmer }:
+{ stdenv, lib, buildPythonPackage, fetchPypi, wasmer, wasmer-compiler-cranelift, pytestCheckHook, pytest-benchmark }:
 
 buildPythonPackage rec {
   pname = "fastdiff";
-  version = "0.2.0";
+  version = "0.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1ai95vjchl4396zjl1b69xfqvn9kn1y7c40d9l0qxdss0pcx6fk2";
+    sha256 = "4dfa09c47832a8c040acda3f1f55fc0ab4d666f0e14e6951e6da78d59acd945a";
   };
 
   postPatch = ''
     substituteInPlace setup.py \
       --replace 'pytest-runner' ""
+    substituteInPlace setup.cfg \
+      --replace "collect_ignore = ['setup.py']" ""
   '';
 
-  propagatedBuildInputs = [ wasmer ];
+  propagatedBuildInputs = [ wasmer wasmer-compiler-cranelift ];
 
   checkInputs = [ pytestCheckHook pytest-benchmark ];
 
   pythonImportsCheck = [ "fastdiff" ];
-  disabledTests = [ "test_native" ];
 
   meta = with lib; {
     description = "A fast native implementation of diff algorithm with a pure Python fallback";
     homepage = "https://github.com/syrusakbary/fastdiff";
     license = licenses.mit;
     maintainers = with maintainers; [ SuperSandro2000 ];
+    # resulting compiled object panics at import
+    broken = stdenv.is32bit;
   };
 }
diff --git a/pkgs/development/python-modules/fastimport/default.nix b/pkgs/development/python-modules/fastimport/default.nix
index fe46405eb3f1..bd5c270d686c 100644
--- a/pkgs/development/python-modules/fastimport/default.nix
+++ b/pkgs/development/python-modules/fastimport/default.nix
@@ -7,13 +7,13 @@
 
 buildPythonPackage rec {
   pname = "fastimport";
-  version = "0.9.13";
+  version = "0.9.14";
 
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "486135a39edb85808fdbbe2c8009197978800a4544fca56cc2074df32e1304f3";
+    sha256 = "6ac99dda4e7b0b3ae831507b6d0094802e6dd95891feafde8cc5c405b6c149ca";
   };
 
   checkPhase = ''
diff --git a/pkgs/development/python-modules/fastparquet/default.nix b/pkgs/development/python-modules/fastparquet/default.nix
index 756d08726c11..56fb6a53e14a 100644
--- a/pkgs/development/python-modules/fastparquet/default.nix
+++ b/pkgs/development/python-modules/fastparquet/default.nix
@@ -5,7 +5,6 @@
 , numba
 , numpy
 , pandas
-, pytest-runner
 , cramjam
 , fsspec
 , thrift
@@ -14,26 +13,32 @@
 
 buildPythonPackage rec {
   pname = "fastparquet";
-  version = "0.7.0";
+  version = "0.7.1";
 
   src = fetchFromGitHub {
     owner = "dask";
     repo = pname;
     rev = version;
-    hash = "sha256-08hanzRnt6WuMriNNtOd+ZHycr2XBeIRav+5sgvT7Do=";
+    hash = "sha256-xV0AXNZSy4LSrHf11OP/+KDbeDQu8yF1ugX+W4mie1E=";
   };
 
-  nativeBuildInputs = [ pytest-runner ];
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "'pytest-runner'," "" \
+      --replace "oldest-supported-numpy" "numpy"
+  '';
+
   propagatedBuildInputs = [ cramjam fsspec numba numpy pandas thrift ];
   checkInputs = [ pytestCheckHook ];
 
   # Workaround https://github.com/NixOS/nixpkgs/issues/123561
   preCheck = ''
     mv fastparquet/test .
-    rm -rf fastparquet
+    rm -r fastparquet
     fastparquet_test="$out"/${python.sitePackages}/fastparquet/test
     ln -s `pwd`/test "$fastparquet_test"
   '';
+
   postCheck = ''
     rm "$fastparquet_test"
   '';
diff --git a/pkgs/development/python-modules/ffmpeg-progress-yield/default.nix b/pkgs/development/python-modules/ffmpeg-progress-yield/default.nix
index 5d2641970721..4b4d6bdd7fc2 100644
--- a/pkgs/development/python-modules/ffmpeg-progress-yield/default.nix
+++ b/pkgs/development/python-modules/ffmpeg-progress-yield/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "ffmpeg-progress-yield";
-  version = "0.0.4";
+  version = "0.1.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e944093e2c1b213da8fa4f0c276c1bad44e0b8ba8be7e4fd001f5132d16baef5";
+    sha256 = "92ae36ff5cf38428bd3695629b5065d161c658fb0de0faf2c20cd7a99dac3820";
   };
 
   propagatedBuildInputs = [ colorama tqdm ];
diff --git a/pkgs/development/python-modules/fiona/default.nix b/pkgs/development/python-modules/fiona/default.nix
index a71e6fbaa7e0..987a8ca6209e 100644
--- a/pkgs/development/python-modules/fiona/default.nix
+++ b/pkgs/development/python-modules/fiona/default.nix
@@ -1,16 +1,16 @@
 { stdenv, lib, buildPythonPackage, fetchPypi, isPy3k, pythonOlder
 , attrs, click, cligj, click-plugins, six, munch, enum34
 , pytestCheckHook, boto3, mock, giflib, pytz
-, gdal
-, certifi
+, gdal, certifi
 }:
 
 buildPythonPackage rec {
-  pname = "Fiona";
+  pname = "fiona";
   version = "1.8.20";
 
   src = fetchPypi {
-    inherit pname version;
+    pname = "Fiona";
+    inherit version;
     sha256 = "a70502d2857b82f749c09cb0dea3726787747933a2a1599b5ab787d74e3c143b";
   };
 
@@ -42,11 +42,15 @@ buildPythonPackage rec {
 
   preCheck = ''
     rm -r fiona # prevent importing local fiona
+    # disable gdal deprecation warnings
+    export GDAL_ENABLE_DEPRECATED_DRIVER_GTM=YES
   '';
 
   disabledTests = [
     # Some tests access network, others test packaging
     "http" "https" "wheel"
+    # Assert not true
+    "test_no_append_driver_cannot_append"
   ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/flask-jwt-extended/default.nix b/pkgs/development/python-modules/flask-jwt-extended/default.nix
index d9eae8ffa585..22be871f745f 100644
--- a/pkgs/development/python-modules/flask-jwt-extended/default.nix
+++ b/pkgs/development/python-modules/flask-jwt-extended/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "Flask-JWT-Extended";
-  version = "4.2.3";
+  version = "4.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "22b8ffa7587d50aaf65f3009f1d55ef7287da8260eaf4655a5837e33479216c3";
+    sha256 = "6e2b40d548b9dfc6051740c4552c097ac38e514e500c16c682d9a533d17ca418";
   };
 
   propagatedBuildInputs = [ python-dateutil flask pyjwt werkzeug ];
diff --git a/pkgs/development/python-modules/flask-migrate/default.nix b/pkgs/development/python-modules/flask-migrate/default.nix
index 26f2ab4aea18..010e79ecbf2c 100644
--- a/pkgs/development/python-modules/flask-migrate/default.nix
+++ b/pkgs/development/python-modules/flask-migrate/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "Flask-Migrate";
-  version = "3.0.1";
+  version = "3.1.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "00m76kgdkk0w5bfq8hbqszpyaqk0yxdvmz4s67lvd36pc7wfhhjd";
+    sha256 = "57d6060839e3a7f150eaab6fe4e726d9e3e7cffe2150fb223d73f92421c6d1d9";
   };
 
   checkInputs = [ flask_script ] ++ lib.optional isPy3k glibcLocales;
diff --git a/pkgs/development/python-modules/flit-core/default.nix b/pkgs/development/python-modules/flit-core/default.nix
index a4c6b99b07f4..7b2731595629 100644
--- a/pkgs/development/python-modules/flit-core/default.nix
+++ b/pkgs/development/python-modules/flit-core/default.nix
@@ -1,7 +1,7 @@
 { lib
 , buildPythonPackage
+, callPackage
 , flit
-, isPy3k
 , toml
 , pytestCheckHook
 , testpath
@@ -12,6 +12,11 @@ buildPythonPackage rec {
   version = "3.2.0";
   format = "pyproject";
 
+  outputs = [
+    "out"
+    "testsout"
+  ];
+
   inherit (flit) src patches;
 
   preConfigure = ''
@@ -22,19 +27,23 @@ buildPythonPackage rec {
     toml
   ];
 
-  checkInputs = [
-    pytestCheckHook
-    testpath
-  ];
+  postInstall = ''
+    mkdir $testsout
+    cp -R ../tests $testsout/tests
+  '';
+
+  # check in passthru.tests.pytest to escape infinite recursion with setuptools-scm
+  doCheck = false;
 
   passthru.tests = {
     inherit flit;
+    pytest = callPackage ./tests.nix { };
   };
 
-  meta = {
+  meta = with lib; {
     description = "Distribution-building parts of Flit. See flit package for more information";
     homepage = "https://github.com/takluyver/flit";
-    license = lib.licenses.bsd3;
-    maintainers = [ lib.maintainers.fridh ];
+    license = licenses.bsd3;
+    maintainers = with maintainers; [ fridh SuperSandro2000 ];
   };
 }
diff --git a/pkgs/development/python-modules/flit-core/tests.nix b/pkgs/development/python-modules/flit-core/tests.nix
new file mode 100644
index 000000000000..0fd13e80cb12
--- /dev/null
+++ b/pkgs/development/python-modules/flit-core/tests.nix
@@ -0,0 +1,22 @@
+{ buildPythonPackage
+, flit
+, flit-core
+, pytestCheckHook
+, testpath
+}:
+
+buildPythonPackage rec {
+  pname = "flit-core";
+  inherit (flit-core) version;
+
+  src = flit-core.testsout;
+
+  dontBuild = true;
+  dontInstall = true;
+
+  checkInputs = [
+    flit
+    pytestCheckHook
+    testpath
+  ];
+}
diff --git a/pkgs/development/python-modules/freetype-py/default.nix b/pkgs/development/python-modules/freetype-py/default.nix
index b0035e838447..13e033e8bc36 100644
--- a/pkgs/development/python-modules/freetype-py/default.nix
+++ b/pkgs/development/python-modules/freetype-py/default.nix
@@ -1,4 +1,12 @@
-{ lib, buildPythonPackage, fetchPypi, substituteAll, stdenv, setuptools-scm, freetype }:
+{ lib
+, stdenv
+, buildPythonPackage
+, fetchPypi
+, substituteAll
+, setuptools-scm
+, freetype
+, pytestCheckHook
+}:
 
 buildPythonPackage rec {
   pname = "freetype-py";
@@ -20,6 +28,14 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [ freetype ];
 
+  preCheck = ''
+    cd tests
+  '';
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
   pythonImportsCheck =  [ "freetype" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/frozendict/default.nix b/pkgs/development/python-modules/frozendict/default.nix
index e172f3815b7e..4acf53563ded 100644
--- a/pkgs/development/python-modules/frozendict/default.nix
+++ b/pkgs/development/python-modules/frozendict/default.nix
@@ -1,16 +1,47 @@
-{ lib, buildPythonPackage, fetchPypi }:
+{ lib
+, buildPythonPackage
+, fetchPypi
+, isPy3k
+, pytestCheckHook
+, setuptoolsBuildHook
+, python
+}:
 
 buildPythonPackage rec {
   pname = "frozendict";
-  version = "1.2";
+  version = "2.0.5";  # 2.0.6 breaks canonicaljson
+  format = "setuptools";
+
+  disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0ibf1wipidz57giy53dh7mh68f2hz38x8f4wdq88mvxj5pr7jhbp";
+    sha256 = "sha256-wb7hwHDY2fZA4SjluHV2pEAAhgCfeGLRPAv4YA5iE9M=";
   };
 
-  # frozendict does not come with tests
-  doCheck = false;
+  pythonImportsCheck = [
+    "frozendict"
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  preCheck = ''
+    rm -r frozendict
+    export PYTHONPATH=$out/${python.sitePackages}:$PYTHONPATH
+  '';
+
+  disabledTests = [
+    # TypeError: unsupported operand type(s) for |=: 'frozendict.frozendict' and 'dict'
+    "test_union"
+  ];
+
+  disabledTestPaths = [
+    # unpackaged test dependency: coold
+    "test/test_coold.py"
+    "test/test_coold_subclass.py"
+  ];
 
   meta = with lib; {
     homepage = "https://github.com/slezica/python-frozendict";
diff --git a/pkgs/development/python-modules/gcovr/default.nix b/pkgs/development/python-modules/gcovr/default.nix
index 1332777189b1..71480ab21131 100644
--- a/pkgs/development/python-modules/gcovr/default.nix
+++ b/pkgs/development/python-modules/gcovr/default.nix
@@ -7,11 +7,11 @@
 
 buildPythonPackage rec {
   pname = "gcovr";
-  version = "4.2";
+  version = "5.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0gyady7x3v3l9fm1zan0idaggqqcm31y7g5vxk7h05p5h7f39bjs";
+    sha256 = "1d80264cbaadff356b3dda71b8c62b3aa803e5b3eb6d526a24932cd6660a2576";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/geoalchemy2/default.nix b/pkgs/development/python-modules/geoalchemy2/default.nix
index c4c0f41d8d17..077523bdb482 100644
--- a/pkgs/development/python-modules/geoalchemy2/default.nix
+++ b/pkgs/development/python-modules/geoalchemy2/default.nix
@@ -1,31 +1,53 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, sqlalchemy
-, shapely
+, packaging
 , setuptools-scm
-, pytest
+, shapely
+, sqlalchemy
+, psycopg2
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "GeoAlchemy2";
-  version = "0.9.3";
+  version = "0.9.4";
+  format = "setuptools";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "56f969cf4ad6629ebcde73e807f7dac0a9375c79991b4f93efab191f37737a00";
+    sha256 = "b0e56d4a945bdc0f8fa9edd50ecc912889ea68e0e3558a19160dcb0d5b1b65fc";
   };
 
-  nativeBuildInputs = [ setuptools-scm ];
-  propagatedBuildInputs = [ sqlalchemy shapely ];
+  nativeBuildInputs = [
+    setuptools-scm
+  ];
 
-  # https://github.com/geoalchemy/geoalchemy2/blob/e05a676350b11f0e73609379dae5625c5de2e868/TEST.rst
-  doCheck = false;
+  propagatedBuildInputs = [
+    packaging
+    shapely
+    sqlalchemy
+  ];
+
+  checkInputs = [
+    psycopg2
+    pytestCheckHook
+  ];
+
+  disabledTestPaths = [
+    # tests require live postgis database
+    "tests/gallery/test_decipher_raster.py"
+    "tests/gallery/test_length_at_insert.py"
+    "tests/gallery/test_summarystatsagg.py"
+    "tests/gallery/test_type_decorator.py"
+    "tests/test_functional.py"
+  ];
 
   meta = with lib; {
+    description = "Toolkit for working with spatial databases";
     homepage =  "http://geoalchemy.org/";
     license = licenses.mit;
-    description = "Toolkit for working with spatial databases";
+    maintainers = with maintainers; [ ];
   };
 
 }
diff --git a/pkgs/development/python-modules/gevent-websocket/default.nix b/pkgs/development/python-modules/gevent-websocket/default.nix
index 7ff62a378ca9..24af4416ab3c 100644
--- a/pkgs/development/python-modules/gevent-websocket/default.nix
+++ b/pkgs/development/python-modules/gevent-websocket/default.nix
@@ -17,10 +17,16 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [ gevent gunicorn ];
 
+  # zero tests run
+  doCheck = false;
+
+  pythonImportsCheck = [ "geventwebsocket" ];
+
   meta = with lib; {
     homepage = "https://www.gitlab.com/noppo/gevent-websocket";
     description = "Websocket handler for the gevent pywsgi server, a Python network library";
     license = licenses.asl20;
+    maintainers = with maintainers; [ ];
   };
 
 }
diff --git a/pkgs/development/python-modules/geventhttpclient/default.nix b/pkgs/development/python-modules/geventhttpclient/default.nix
index 5563ff94baf5..fd759a0bd723 100644
--- a/pkgs/development/python-modules/geventhttpclient/default.nix
+++ b/pkgs/development/python-modules/geventhttpclient/default.nix
@@ -1,32 +1,49 @@
 { lib
 , buildPythonPackage
-, fetchPypi
-, pytest
-, gevent
-, certifi
-, six
-, backports_ssl_match_hostname
 , pythonOlder
+, fetchPypi
+, backports_ssl_match_hostname
+, brotli
+, certifi
+, gevent
+, six
+, dpkt
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "geventhttpclient";
-  version = "1.4.5";
+  version = "1.5.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3f0ab18d84ef26ba0c9df73ae2a41ba30a46072b447f2e36c740400de4a63d44";
+    sha256 = "4aead64253d2769a6528544f7812ce8d71ae13551d079f2d9a3533d72818f2e0";
   };
 
-  buildInputs = [ pytest ];
-  propagatedBuildInputs = [ gevent certifi six ]
-    ++ lib.optionals (pythonOlder "3.7") [ backports_ssl_match_hostname ];
+  propagatedBuildInputs = [
+    brotli
+    certifi
+    gevent
+    six
+  ] ++ lib.optionals (pythonOlder "3.7") [
+    backports_ssl_match_hostname
+  ];
 
-  # Several tests fail that require network
-  doCheck = false;
-  checkPhase = ''
-    py.test $out
-  '';
+  checkInputs = [
+    dpkt
+    pytestCheckHook
+  ];
+
+  disabledTests = [
+    # socket.gaierror: [Errno -2] Name or service not known
+    "test_client_simple"
+    "test_client_without_leading_slas"
+    "test_request_with_headers"
+    "test_response_context_manager"
+    "test_client_ssl"
+    "test_ssl_fail_invalid_certificate"
+    "test_multi_queries_greenlet_safe"
+  ];
 
   meta = with lib; {
     homepage = "https://github.com/gwik/geventhttpclient";
diff --git a/pkgs/development/python-modules/google-api-python-client/default.nix b/pkgs/development/python-modules/google-api-python-client/default.nix
index 2fd9247c8825..45d6044b8ea7 100644
--- a/pkgs/development/python-modules/google-api-python-client/default.nix
+++ b/pkgs/development/python-modules/google-api-python-client/default.nix
@@ -4,11 +4,11 @@
 
 buildPythonPackage rec {
   pname = "google-api-python-client";
-  version = "2.15.0";
+  version = "2.18.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-g3VIkjKCP0TGARlqlgUF4D7FjJXdtkFcax0ddrRo+Lo=";
+    sha256 = "a25661ec6cf4c159f41fe9c061c2bee31b2dddaf2ad787e23617048a25b53842";
   };
 
   # No tests included in archive
diff --git a/pkgs/development/python-modules/google-cloud-bigquery-datatransfer/default.nix b/pkgs/development/python-modules/google-cloud-bigquery-datatransfer/default.nix
index f6a62c544cf4..62956e1e46de 100644
--- a/pkgs/development/python-modules/google-cloud-bigquery-datatransfer/default.nix
+++ b/pkgs/development/python-modules/google-cloud-bigquery-datatransfer/default.nix
@@ -11,11 +11,11 @@
 
 buildPythonPackage rec {
   pname = "google-cloud-bigquery-datatransfer";
-  version = "3.3.1";
+  version = "3.3.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-oCktt8wAYKewz6Ga4mIGVy0IWonXTqQvaO5MT4MkHMY=";
+    sha256 = "fcb71ebe5c5b232d24fe7d666b65709e4fc8db43263c8182e5ed8e5a52abefec";
   };
 
   propagatedBuildInputs = [ google-api-core libcst proto-plus ];
diff --git a/pkgs/development/python-modules/google-cloud-testutils/default.nix b/pkgs/development/python-modules/google-cloud-testutils/default.nix
index 05a66406ce02..2c208511ee3f 100644
--- a/pkgs/development/python-modules/google-cloud-testutils/default.nix
+++ b/pkgs/development/python-modules/google-cloud-testutils/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "google-cloud-testutils";
-  version = "1.0.0";
+  version = "1.1.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-2RaRhRvgnmr/trjAE+RBlVO5AZ54YEFcoRwcPCKCTKs=";
+    sha256 = "3d79051b6ca170c2a4f159bf56ac3f66c1e5360486121e72c06fdaa3911154bf";
   };
 
   propagatedBuildInputs = [ click google-auth six ];
diff --git a/pkgs/development/python-modules/google-crc32c/default.nix b/pkgs/development/python-modules/google-crc32c/default.nix
index b36635654a9d..41b23321af98 100644
--- a/pkgs/development/python-modules/google-crc32c/default.nix
+++ b/pkgs/development/python-modules/google-crc32c/default.nix
@@ -2,13 +2,13 @@
 
 buildPythonPackage rec {
   pname = "google-crc32c";
-  version = "1.1.2";
+  version = "1.1.3";
 
   src = fetchFromGitHub {
     owner = "googleapis";
     repo = "python-crc32c";
     rev = "v${version}";
-    sha256 = "058g69yp7x41mv0d84yp31jv64fpm4r25b86rvvqgc6n74w6jj7k";
+    sha256 = "1m2hafyfagvyabizr4fhcp2s2s3x56k006fhvl1qzk994qjhyzqk";
   };
 
   buildInputs = [ crc32c ];
diff --git a/pkgs/development/python-modules/gradient/default.nix b/pkgs/development/python-modules/gradient/default.nix
index 57b58699ec38..7e47faadc0e2 100644
--- a/pkgs/development/python-modules/gradient/default.nix
+++ b/pkgs/development/python-modules/gradient/default.nix
@@ -22,11 +22,11 @@
 
 buildPythonPackage rec {
   pname = "gradient";
-  version = "1.5.5";
+  version = "1.7.4";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fee5016afe5e61a640bb9d7e234a10926c17c9e83c876b617438ff5f5ce039ad";
+    sha256 = "de1d33672f13d4de37a66ba9aebfd503a098d0ca26e5eb8b071e1c0dacd557ea";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/graphql-core/default.nix b/pkgs/development/python-modules/graphql-core/default.nix
index 7ac25424616a..1909dd99fe0f 100644
--- a/pkgs/development/python-modules/graphql-core/default.nix
+++ b/pkgs/development/python-modules/graphql-core/default.nix
@@ -8,14 +8,14 @@
 
 buildPythonPackage rec {
   pname = "graphql-core";
-  version = "3.1.5";
+  version = "3.1.6";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "graphql-python";
     repo = pname;
     rev = "v${version}";
-    sha256 = "055gfvyax781f4zk4pl60y8yd90bnn4rkqh5i48pczaff0lwlfj1";
+    sha256 = "1ip0yrqmnqncgpwvba18x020gkwr7csiw4zdy6mrdnvwf5qyam4x";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/green/default.nix b/pkgs/development/python-modules/green/default.nix
index 934c363245d7..0320a3858be1 100644
--- a/pkgs/development/python-modules/green/default.nix
+++ b/pkgs/development/python-modules/green/default.nix
@@ -8,13 +8,13 @@
 
 buildPythonPackage rec {
   pname = "green";
-  version = "3.2.6";
+  version = "3.3.0";
 
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e51d4ff6e6885942d944304fedc7440a8f87917aa09526beeecb31a0dae655b8";
+    sha256 = "a4d86f2dfa4ccbc86f24bcb9c9ab8bf34219c876c24e9f0603aab4dfe73bb575";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/greenlet/default.nix b/pkgs/development/python-modules/greenlet/default.nix
index 4d829f3d6473..e997c7da3987 100644
--- a/pkgs/development/python-modules/greenlet/default.nix
+++ b/pkgs/development/python-modules/greenlet/default.nix
@@ -9,12 +9,12 @@
 
 buildPythonPackage rec {
   pname = "greenlet";
-  version = "1.1.0";
+  version = "1.1.1";
   disabled = isPyPy;  # builtin for pypy
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c87df8ae3f01ffb4483c796fe1b15232ce2b219f0b18126948616224d3f658ee";
+    sha256 = "c0f22774cd8294078bdf7392ac73cf00bfa1e5e0ed644bd064fdabc5f2a2f481";
   };
 
   checkPhase = ''
diff --git a/pkgs/development/python-modules/h5py/default.nix b/pkgs/development/python-modules/h5py/default.nix
index 9e5921bb412d..dfa4288e54fc 100644
--- a/pkgs/development/python-modules/h5py/default.nix
+++ b/pkgs/development/python-modules/h5py/default.nix
@@ -8,13 +8,13 @@ let
   mpi = hdf5.mpi;
   mpiSupport = hdf5.mpiSupport;
 in buildPythonPackage rec {
-  version = "3.2.1";
+  version = "3.4.0";
   pname = "h5py";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-iUdL6RG/zbNMvw2YuOxItXjCeon9sa5O51E/HvjZJJ4=";
+    sha256 = "ee1c683d91ab010d5e85cb61e8f9e7ee0d8eab545bf3dd50a9618f1d0e8f615e";
   };
 
   # avoid strict pinning of numpy
diff --git a/pkgs/development/python-modules/hdbscan/default.nix b/pkgs/development/python-modules/hdbscan/default.nix
index bf48d6cf5e76..9fa932c7e418 100644
--- a/pkgs/development/python-modules/hdbscan/default.nix
+++ b/pkgs/development/python-modules/hdbscan/default.nix
@@ -44,6 +44,8 @@ buildPythonPackage rec {
     "test_hdbscan_boruvka_balltree_matches"
   ];
 
+  pythonImportsCheck = [ "hdbscan" ];
+
   meta = with lib; {
     description = "Hierarchical Density-Based Spatial Clustering of Applications with Noise, a clustering algorithm with a scikit-learn compatible API";
     homepage =  "https://github.com/scikit-learn-contrib/hdbscan";
diff --git a/pkgs/development/python-modules/hstspreload/default.nix b/pkgs/development/python-modules/hstspreload/default.nix
index 7b92aeb269df..ecdfb790ebca 100644
--- a/pkgs/development/python-modules/hstspreload/default.nix
+++ b/pkgs/development/python-modules/hstspreload/default.nix
@@ -6,14 +6,14 @@
 
 buildPythonPackage rec {
   pname = "hstspreload";
-  version = "2021.8.1";
+  version = "2021.9.1";
   disabled = isPy27;
 
   src = fetchFromGitHub {
     owner = "sethmlarson";
     repo = pname;
     rev = version;
-    sha256 = "0si22p461qydh874gkidiar89hrfx7lm7r7g6d1qi7lz8wlwcplv";
+    sha256 = "sha256-CZlXnRe4yA6VJF48t73m2PbBRFzg0XTgT7J1N83Ojc4=";
   };
 
   # tests require network connection
diff --git a/pkgs/development/python-modules/httpretty/default.nix b/pkgs/development/python-modules/httpretty/default.nix
index f0c0b9b2ee99..78a529666139 100644
--- a/pkgs/development/python-modules/httpretty/default.nix
+++ b/pkgs/development/python-modules/httpretty/default.nix
@@ -19,7 +19,7 @@
 
 buildPythonPackage rec {
   pname = "httpretty";
-  version = "1.1.3";
+  version = "1.1.4";
 
   # drop this for version > 0.9.7
   # Flaky tests: https://github.com/gabrielfalcao/HTTPretty/pull/394
@@ -27,7 +27,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "229ade39175ea4324e767f29dc24e5f846fbc72bf80e1a919b2547a6574ff601";
+    sha256 = "20de0e5dd5a18292d36d928cc3d6e52f8b2ac73daec40d41eb62dee154933b68";
   };
 
   propagatedBuildInputs = [ six ];
diff --git a/pkgs/development/python-modules/httptools/default.nix b/pkgs/development/python-modules/httptools/default.nix
index 54b512be1fd4..0a5b510b0ad9 100644
--- a/pkgs/development/python-modules/httptools/default.nix
+++ b/pkgs/development/python-modules/httptools/default.nix
@@ -6,12 +6,12 @@
 
 buildPythonPackage rec {
   pname = "httptools";
-  version = "0.2.0";
+  version = "0.3.0";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "94505026be56652d7a530ab03d89474dc6021019d6b8682281977163b3471ea0";
+    sha256 = "3f9b4856d46ba1f0c850f4e84b264a9a8b4460acb20e865ec00978ad9fbaa4cf";
   };
 
   # tests are not included in pypi tarball
diff --git a/pkgs/development/python-modules/httpx/default.nix b/pkgs/development/python-modules/httpx/default.nix
index 6a9300566d59..014272bcc107 100644
--- a/pkgs/development/python-modules/httpx/default.nix
+++ b/pkgs/development/python-modules/httpx/default.nix
@@ -4,6 +4,7 @@
 , fetchFromGitHub
 , brotlicffi
 , certifi
+, charset-normalizer
 , h2
 , httpcore
 , rfc3986
@@ -18,19 +19,20 @@
 
 buildPythonPackage rec {
   pname = "httpx";
-  version = "0.18.2";
+  version = "0.19.0";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "encode";
     repo = pname;
     rev = version;
-    sha256 = "0rr5b6z96yipvp4riqmmbkbcy0sdyzykcdwf5y9ryh27pxr8q8x4";
+    sha256 = "sha256-bUxxeUYqOHBmSL2gPQG5cIq6k5QY4Kyhj9ToA5yZXPA=";
   };
 
   propagatedBuildInputs = [
     brotlicffi
     certifi
+    charset-normalizer
     h2
     httpcore
     rfc3986
diff --git a/pkgs/development/python-modules/humanize/default.nix b/pkgs/development/python-modules/humanize/default.nix
index 4c5bd0e3af25..85ec6257ea5d 100644
--- a/pkgs/development/python-modules/humanize/default.nix
+++ b/pkgs/development/python-modules/humanize/default.nix
@@ -9,13 +9,13 @@
 }:
 
 buildPythonPackage rec {
-  version = "3.9.0";
+  version = "3.11.0";
   pname = "humanize";
   disabled = isPy27; # setup.py no longer compatible
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "892a5b7b87763c4c6997a58382c2b1f4614048a2e01c23ef1bb0456e6f9d4d5d";
+    sha256 = "4160cdc63fcd0daac27d2e1e218a31bb396fc3fe5712d153675d89432a03778f";
   };
 
   nativeBuildInputs = [ setuptools-scm ];
diff --git a/pkgs/development/python-modules/hypothesis/default.nix b/pkgs/development/python-modules/hypothesis/default.nix
index 35f53864eb9d..4d0a1713d954 100644
--- a/pkgs/development/python-modules/hypothesis/default.nix
+++ b/pkgs/development/python-modules/hypothesis/default.nix
@@ -18,14 +18,14 @@ buildPythonPackage rec {
   # If you need these, you can just add them to your environment.
 
   pname = "hypothesis";
-  version = "6.14.0";
+  version = "6.17.3";
 
   # Use github tarballs that includes tests
   src = fetchFromGitHub {
     owner = "HypothesisWorks";
     repo = "hypothesis-python";
     rev = "hypothesis-python-${version}";
-    sha256 = "0yns81j3fnpdfaphk722xcnidqhgy0kmd7ik6aw7l795l0wivhxj";
+    sha256 = "1g96q3l97lq3xps36cv147dvj44nh1b0k67z817x7zfwyw844sgn";
   };
 
   postUnpack = "sourceRoot=$sourceRoot/hypothesis-python";
diff --git a/pkgs/development/python-modules/hypothesmith/default.nix b/pkgs/development/python-modules/hypothesmith/default.nix
index 4bf1ca8d02f7..0d175989271c 100644
--- a/pkgs/development/python-modules/hypothesmith/default.nix
+++ b/pkgs/development/python-modules/hypothesmith/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "hypothesmith";
-  version = "0.1.8";
+  version = "0.1.9";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-+f8EexXE7TEs49pX6idXD4bWtTzhKvnyXlnmV2oAQQo=";
+    sha256 = "039fd6aa0102f89df9df7ad4cff70aa8068678c13c3be2713c92568917317a04";
   };
 
   propagatedBuildInputs = [ hypothesis lark-parser libcst ];
diff --git a/pkgs/development/python-modules/ibm-cloud-sdk-core/default.nix b/pkgs/development/python-modules/ibm-cloud-sdk-core/default.nix
index 8e7f4832c254..cc7572499da1 100644
--- a/pkgs/development/python-modules/ibm-cloud-sdk-core/default.nix
+++ b/pkgs/development/python-modules/ibm-cloud-sdk-core/default.nix
@@ -1,11 +1,8 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, codecov
 , pyjwt
-, pylint
 , pytestCheckHook
-, pytest-cov
 , python-dateutil
 , requests
 , responses
@@ -14,30 +11,27 @@
 
 buildPythonPackage rec {
   pname = "ibm-cloud-sdk-core";
-  version = "3.10.0";
+  version = "3.11.3";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ab9520be99066ec41a24e31ac653c28953adc8fc349f0fa53a598e1802a79cd6";
+    sha256 = "c855d0111dd570f36497cdb8c11510ae8d14fb70698f20529e19f88485266233";
   };
 
-  checkInputs = [
-    codecov
-    pylint
-    pytestCheckHook
-    pytest-cov
-    responses
-    tox
-  ];
-
   propagatedBuildInputs = [
     pyjwt
     python-dateutil
     requests
   ];
 
-  # Various tests try to access credential files which are not included with the source distribution
+  checkInputs = [
+    pytestCheckHook
+    responses
+    tox
+  ];
+
   disabledTests = [
+    # Various tests try to access credential files which are not included with the source distribution
     "test_configure_service"
     "test_cp4d_authenticator"
     "test_cwd"
@@ -49,6 +43,12 @@ buildPythonPackage rec {
     "test_iam"
     "test_read_external_sources_2"
     "test_retry_config_external"
+    # assertion error due to requests brotli support
+    "test_http_client"
+  ];
+
+  disabledTestPaths = [
+    "test/test_container_token_manager.py"
   ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/ibm-watson/default.nix b/pkgs/development/python-modules/ibm-watson/default.nix
index 49e4541143e9..9e5198a1cb30 100644
--- a/pkgs/development/python-modules/ibm-watson/default.nix
+++ b/pkgs/development/python-modules/ibm-watson/default.nix
@@ -14,13 +14,13 @@
 
 buildPythonPackage rec {
   pname = "ibm-watson";
-  version = "5.2.2";
+  version = "5.2.3";
 
   src = fetchFromGitHub {
     owner = "watson-developer-cloud";
     repo = "python-sdk";
     rev = "v${version}";
-    sha256 = "sha256-bK6lcTKAVwAJDb5LqKRWR/4wcOKx7bRwWYC+WB5qJE4=";
+    sha256 = "0i0zs38hqgh2510b3690nrq2pvx7wcdlv9iyjgsrfl7gid8qi3ng";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/imageio-ffmpeg/default.nix b/pkgs/development/python-modules/imageio-ffmpeg/default.nix
index 9d1755d81b97..a249b2dbfe19 100644
--- a/pkgs/development/python-modules/imageio-ffmpeg/default.nix
+++ b/pkgs/development/python-modules/imageio-ffmpeg/default.nix
@@ -9,13 +9,13 @@
 
 buildPythonPackage rec {
   pname = "imageio-ffmpeg";
-  version = "0.4.4";
+  version = "0.4.5";
 
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "73640a7a54f95e607addd637c766d56be31d975a64ddb97d14df012575ef1a5d";
+    sha256 = "f2ea4245a2adad25dedf98d343159579167e549ac8c4691cef5eff980e20c139";
   };
 
   patches = [
diff --git a/pkgs/development/python-modules/imap-tools/default.nix b/pkgs/development/python-modules/imap-tools/default.nix
index d1cecdda42d9..ef13bf471e16 100644
--- a/pkgs/development/python-modules/imap-tools/default.nix
+++ b/pkgs/development/python-modules/imap-tools/default.nix
@@ -7,7 +7,7 @@
 
 buildPythonPackage rec {
   pname = "imap-tools";
-  version = "0.44.0";
+  version = "0.46.0";
 
   disabled = isPy27;
 
@@ -15,7 +15,7 @@ buildPythonPackage rec {
     owner = "ikvk";
     repo = "imap_tools";
     rev = "v${version}";
-    sha256 = "sha256-C9396yRSowaLe3E1s+rw8bah77znjfoIhLwJpcqhN6Y=";
+    sha256 = "08a4p4q96zz6qp3cy7hs5jn9h2gf68d8zchw4w0kk83sm1r8rpxw";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/imdbpy/default.nix b/pkgs/development/python-modules/imdbpy/default.nix
index dea62f080093..ab7575f99be8 100644
--- a/pkgs/development/python-modules/imdbpy/default.nix
+++ b/pkgs/development/python-modules/imdbpy/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "IMDbPY";
-  version = "2020.9.25";
+  version = "2021.4.18";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1p3j9j1jcgbw4626cvgpryhvczy9gzlg0laz6lflgq17m129gin2";
+    sha256 = "af57f03638ba3b8ab3d696bfef0eeaf6414385c85f09260aba0a16b32174853f";
   };
 
   patches = [ ./sql_error.patch ]; # Already fixed in master, but not yet in the current release. This can be removed upon the next version update
diff --git a/pkgs/development/python-modules/iminuit/default.nix b/pkgs/development/python-modules/iminuit/default.nix
index 42a1d7c4ffdb..cd598d602a29 100644
--- a/pkgs/development/python-modules/iminuit/default.nix
+++ b/pkgs/development/python-modules/iminuit/default.nix
@@ -2,12 +2,12 @@
 
 buildPythonPackage rec {
   pname = "iminuit";
-  version = "2.6.1";
+  version = "2.8.2";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "5fb8786bcad53762648ddacb008d18b49704ba5c011ade240004bfc5a628b4f6";
+    sha256 = "ffba627a638fe233bbef03e91af6063c1e5d62405327219b03f0abf50196a95b";
   };
 
   nativeBuildInputs = [ cmake ];
diff --git a/pkgs/development/python-modules/immutabledict/default.nix b/pkgs/development/python-modules/immutabledict/default.nix
index 54fef8720ca5..b45b852f85fc 100644
--- a/pkgs/development/python-modules/immutabledict/default.nix
+++ b/pkgs/development/python-modules/immutabledict/default.nix
@@ -7,22 +7,16 @@
 
 buildPythonPackage rec {
   pname = "immutabledict";
-  version = "2.1.0";
+  version = "2.2.0";
   format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "corenting";
     repo = "immutabledict";
     rev = "v${version}";
-    sha256 = "1n71154nfb6vr41iv00xcwkxmwnn1vwzbr3s23bjvlhvmnjb48a8";
+    sha256 = "sha256-Jf7ad3ImPfEvCBrUZ1NVXMCBqwLmd0hwpKfe9rVsehc=";
   };
 
-  # https://github.com/corenting/immutabledict/issues/56
-  postPatch = ''
-    substituteInPlace pyproject.toml \
-      --replace "poetry.masonry.api" "poetry.core.masonry.api"
-  '';
-
   nativeBuildInputs = [
     poetry-core
   ];
diff --git a/pkgs/development/python-modules/inflect/default.nix b/pkgs/development/python-modules/inflect/default.nix
index 9081a30ac6be..ca454d432317 100644
--- a/pkgs/development/python-modules/inflect/default.nix
+++ b/pkgs/development/python-modules/inflect/default.nix
@@ -3,7 +3,6 @@
 , fetchPypi
 , isPy27
 , setuptools-scm
-, toml
 , pytestCheckHook
 }:
 
@@ -17,7 +16,7 @@ buildPythonPackage rec {
     sha256 = "41a23f6788962e9775e40e2ecfb1d6455d02de315022afeedd3c5dc070019d73";
   };
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
 
   checkInputs = [ pytestCheckHook ];
 
diff --git a/pkgs/development/python-modules/inform/default.nix b/pkgs/development/python-modules/inform/default.nix
index 2397c0bc4db6..9ef6fd1e0a1d 100644
--- a/pkgs/development/python-modules/inform/default.nix
+++ b/pkgs/development/python-modules/inform/default.nix
@@ -7,13 +7,13 @@
 
 buildPythonPackage rec {
   pname = "inform";
-  version = "1.24";
+  version = "1.25";
 
   src = fetchFromGitHub {
     owner = "KenKundert";
     repo = "inform";
     rev = "v${version}";
-    sha256 = "114cyff00j9r7qm2ld4w1a4kklr5gx570vk67p56gpr2553dkmly";
+    sha256 = "1r56wmn21c7ggy33548l6dfjswhadkp2iaalfb7xgsxmq7qfcnax";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/intake/default.nix b/pkgs/development/python-modules/intake/default.nix
index fff6d74b56a1..3a959b897216 100644
--- a/pkgs/development/python-modules/intake/default.nix
+++ b/pkgs/development/python-modules/intake/default.nix
@@ -23,12 +23,12 @@
 
 buildPythonPackage rec {
   pname = "intake";
-  version = "0.6.2";
+  version = "0.6.3";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b0cab1d185a703acb38eecb9cff3edd5cc7004fe18a36d5e42a8f7fffc9cca1c";
+    sha256 = "f64543353f30d9440b953984f78b7a0954e5756d70c64243609d307ba488014f";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/invoke/default.nix b/pkgs/development/python-modules/invoke/default.nix
index 08d72cec4961..45c341c209cf 100644
--- a/pkgs/development/python-modules/invoke/default.nix
+++ b/pkgs/development/python-modules/invoke/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "invoke";
-  version = "1.5.0";
+  version = "1.6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f0c560075b5fb29ba14dad44a7185514e94970d1b9d57dcd3723bec5fed92650";
+    sha256 = "374d1e2ecf78981da94bfaf95366216aaec27c2d6a7b7d5818d92da55aa258d3";
   };
 
   patchPhase = ''
diff --git a/pkgs/development/python-modules/ipykernel/default.nix b/pkgs/development/python-modules/ipykernel/default.nix
index 0d44c406349d..041818900978 100644
--- a/pkgs/development/python-modules/ipykernel/default.nix
+++ b/pkgs/development/python-modules/ipykernel/default.nix
@@ -1,56 +1,39 @@
 { lib
 , stdenv
 , buildPythonPackage
+, callPackage
 , fetchPypi
-, flaky
+, debugpy
 , ipython
 , jupyter_client
-, traitlets
 , tornado
+, traitlets
 , pythonOlder
-, pytestCheckHook
-, nose
 }:
 
 buildPythonPackage rec {
   pname = "ipykernel";
-  version = "5.5.5";
+  version = "6.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e976751336b51082a89fc2099fb7f96ef20f535837c398df6eab1283c2070884";
+    sha256 = "5314690a638f893e2cc3bf3d25042920e9fbb873f7d8263033390264caeb95f4";
   };
 
-  propagatedBuildInputs = [ ipython jupyter_client traitlets tornado ];
+  propagatedBuildInputs = [
+    debugpy
+    ipython
+    jupyter_client
+    tornado
+    traitlets
+  ];
 
-  checkInputs = [ pytestCheckHook nose flaky ];
-  dontUseSetuptoolsCheck = true;
-  preCheck = ''
-    export HOME=$(mktemp -d)
-  '';
-  disabledTests = lib.optionals stdenv.isDarwin ([
-    # see https://github.com/NixOS/nixpkgs/issues/76197
-    "test_subprocess_print"
-    "test_subprocess_error"
-    "test_ipython_start_kernel_no_userns"
+  # check in passthru.tests.pytest to escape infinite recursion with ipyparallel
+  doCheck = false;
 
-    # https://github.com/ipython/ipykernel/issues/506
-    "test_unc_paths"
-  ] ++ lib.optionals (pythonOlder "3.8") [
-    # flaky test https://github.com/ipython/ipykernel/issues/485
-    "test_shutdown"
-
-    # test regression https://github.com/ipython/ipykernel/issues/486
-    "test_sys_path_profile_dir"
-    "test_save_history"
-    "test_help_output"
-    "test_write_kernel_spec"
-    "test_ipython_start_kernel_userns"
-    "ZMQDisplayPublisherTests"
-  ]);
-
-  # Some of the tests use localhost networking.
-  __darwinAllowLocalNetworking = true;
+  passthru.tests = {
+    pytest = callPackage ./tests.nix { };
+  };
 
   meta = {
     description = "IPython Kernel for Jupyter";
diff --git a/pkgs/development/python-modules/ipykernel/tests.nix b/pkgs/development/python-modules/ipykernel/tests.nix
new file mode 100644
index 000000000000..9375dbc2bfdc
--- /dev/null
+++ b/pkgs/development/python-modules/ipykernel/tests.nix
@@ -0,0 +1,57 @@
+{ lib
+, stdenv
+, buildPythonPackage
+, pythonOlder
+, flaky
+, ipykernel
+, ipyparallel
+, nose
+, pytestCheckHook
+
+}:
+
+buildPythonPackage rec {
+  pname = "ipykernel-tests";
+  inherit (ipykernel) version;
+
+  src = ipykernel.src;
+
+  dontBuild = true;
+  dontInstall = true;
+
+  checkInputs = [
+    flaky
+    ipykernel
+    ipyparallel
+    nose
+    pytestCheckHook
+  ];
+
+  preCheck = ''
+    export HOME=$(mktemp -d)
+  '';
+
+  disabledTests = lib.optionals stdenv.isDarwin ([
+    # see https://github.com/NixOS/nixpkgs/issues/76197
+    "test_subprocess_print"
+    "test_subprocess_error"
+    "test_ipython_start_kernel_no_userns"
+
+    # https://github.com/ipython/ipykernel/issues/506
+    "test_unc_paths"
+  ] ++ lib.optionals (pythonOlder "3.8") [
+    # flaky test https://github.com/ipython/ipykernel/issues/485
+    "test_shutdown"
+
+    # test regression https://github.com/ipython/ipykernel/issues/486
+    "test_sys_path_profile_dir"
+    "test_save_history"
+    "test_help_output"
+    "test_write_kernel_spec"
+    "test_ipython_start_kernel_userns"
+    "ZMQDisplayPublisherTests"
+  ]);
+
+  # Some of the tests use localhost networking.
+  __darwinAllowLocalNetworking = true;
+}
diff --git a/pkgs/development/python-modules/ipython/default.nix b/pkgs/development/python-modules/ipython/default.nix
index e036a3378643..548ba874cd70 100644
--- a/pkgs/development/python-modules/ipython/default.nix
+++ b/pkgs/development/python-modules/ipython/default.nix
@@ -23,12 +23,12 @@
 
 buildPythonPackage rec {
   pname = "ipython";
-  version = "7.24.1";
+  version = "7.27.0";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "9bc24a99f5d19721fb8a2d1408908e9c0520a17fff2233ffe82620847f17f1b6";
+    sha256 = "58b55ebfdfa260dad10d509702dc2857cb25ad82609506b070cf2d7b7df5af13";
   };
 
   prePatch = lib.optionalString stdenv.isDarwin ''
diff --git a/pkgs/development/python-modules/irc/default.nix b/pkgs/development/python-modules/irc/default.nix
index 60a960a204c4..423ec4ecf292 100644
--- a/pkgs/development/python-modules/irc/default.nix
+++ b/pkgs/development/python-modules/irc/default.nix
@@ -1,6 +1,6 @@
 { lib, buildPythonPackage, fetchPypi, isPy3k
 , six, jaraco_logging, jaraco_text, jaraco_stream, pytz, jaraco_itertools
-, setuptools-scm, jaraco_collections, importlib-metadata, toml
+, setuptools-scm, jaraco_collections, importlib-metadata
 }:
 
 buildPythonPackage rec {
@@ -28,7 +28,6 @@ buildPythonPackage rec {
     pytz
     jaraco_itertools
     jaraco_collections
-    toml
   ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/islpy/default.nix b/pkgs/development/python-modules/islpy/default.nix
index 736588aa4504..918d8be8e9f1 100644
--- a/pkgs/development/python-modules/islpy/default.nix
+++ b/pkgs/development/python-modules/islpy/default.nix
@@ -11,12 +11,12 @@
 
 buildPythonPackage rec {
   pname = "islpy";
-  version = "2020.2.2";
+  version = "2021.1";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "7eb7dfa41d6a67d9ee4ea4bb9f08bdbcbee42b364502136b7882cfd80ff427e0";
+    sha256 = "b3f49de925149dbf2482e648016507cd66d0dce6668a1bc4de5e7a937e9c576d";
   };
 
   postConfigure = ''
diff --git a/pkgs/development/python-modules/isort/default.nix b/pkgs/development/python-modules/isort/default.nix
index 1195f0f6b097..b55fb9156814 100644
--- a/pkgs/development/python-modules/isort/default.nix
+++ b/pkgs/development/python-modules/isort/default.nix
@@ -6,17 +6,16 @@
 , pytestCheckHook
 }:
 
-let
-in buildPythonPackage rec {
+buildPythonPackage rec {
   pname = "isort";
-  version = "5.6.4";
+  version = "5.9.3";
   format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "PyCQA";
     repo = "isort";
     rev = version;
-    sha256 = "1m7jpqssnbsn1ydrw1dn7nrcrggqcvj9v6mk5ampxmvk94xd2r2q";
+    sha256 = "sha256-JbRZ/3Xz35tGoCNnQesR08Sjoz3yimxZyxhhOXGvmXw=";
   };
 
   nativeBuildInputs = [
@@ -46,6 +45,7 @@ in buildPythonPackage rec {
   '';
 
   pytestFlagsArray = [
+    "--ignore=tests/benchmark/" # requires pytest-benchmark
     "--ignore=tests/integration/" # pulls in 10 other packages
     "--ignore=tests/unit/profiles/test_black.py" # causes infinite recursion to include black
   ];
@@ -63,6 +63,7 @@ in buildPythonPackage rec {
     # plugin not available
     "test_isort_literals_issue_1358"
     "test_isort_supports_formatting_plugins_issue_1353"
+    "test_sort_configurable_sort_issue_1732"
     "test_value_assignment_list"
     # profiles not available
     "test_isort_supports_shared_profiles_issue_970"
diff --git a/pkgs/development/python-modules/iterm2/default.nix b/pkgs/development/python-modules/iterm2/default.nix
index 3b98f25c566f..a1b777c1bb76 100644
--- a/pkgs/development/python-modules/iterm2/default.nix
+++ b/pkgs/development/python-modules/iterm2/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "iterm2";
-  version = "1.21";
+  version = "1.27";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "06be59e0314a2f0f32753eb2d44eb563e85253875bc8da64df5b4eeba7fc05bd";
+    sha256 = "dcbd89d0502e72a9a41b055f5cf10b5a991f60fb12df29918d9c2183d1389abd";
   };
 
   propagatedBuildInputs = [ protobuf websockets ];
diff --git a/pkgs/development/python-modules/jaraco_classes/default.nix b/pkgs/development/python-modules/jaraco_classes/default.nix
index a727e774ec30..aadb9f9028f1 100644
--- a/pkgs/development/python-modules/jaraco_classes/default.nix
+++ b/pkgs/development/python-modules/jaraco_classes/default.nix
@@ -1,5 +1,5 @@
 { lib, buildPythonPackage, fetchFromGitHub, isPy27
-, setuptools-scm, toml
+, setuptools-scm
 , more-itertools
 , pytestCheckHook
 }:
@@ -20,7 +20,7 @@ buildPythonPackage rec {
 
   SETUPTOOLS_SCM_PRETEND_VERSION = version;
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
 
   propagatedBuildInputs = [ more-itertools ];
 
diff --git a/pkgs/development/python-modules/jaraco_collections/default.nix b/pkgs/development/python-modules/jaraco_collections/default.nix
index 060d45938118..46f2bfdff3fc 100644
--- a/pkgs/development/python-modules/jaraco_collections/default.nix
+++ b/pkgs/development/python-modules/jaraco_collections/default.nix
@@ -4,10 +4,10 @@
 
 buildPythonPackage rec {
   pname = "jaraco.collections";
-  version = "3.3.0";
+  version = "3.4.0";
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3662267424b55f10bf15b6f5dee6a6e48a2865c0ec50cc7a16040c81c55a98dc";
+    sha256 = "344d14769d716e7496af879ac71b3c6ebdd46abc64bd9ec21d15248365aa3ac9";
   };
 
   pythonNamespaces = [ "jaraco" ];
diff --git a/pkgs/development/python-modules/jaraco_functools/default.nix b/pkgs/development/python-modules/jaraco_functools/default.nix
index 1fca58ebf733..3ad652af7643 100644
--- a/pkgs/development/python-modules/jaraco_functools/default.nix
+++ b/pkgs/development/python-modules/jaraco_functools/default.nix
@@ -1,5 +1,5 @@
 { lib, buildPythonPackage, fetchPypi
-, setuptools-scm, toml
+, setuptools-scm
 , more-itertools, backports_functools_lru_cache }:
 
 buildPythonPackage rec {
@@ -11,7 +11,7 @@ buildPythonPackage rec {
     sha256 = "bfcf7da71e2a0e980189b0744b59dba6c1dcf66dcd7a30f8a4413e478046b314";
   };
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
 
   propagatedBuildInputs = [ more-itertools backports_functools_lru_cache ];
 
diff --git a/pkgs/development/python-modules/jaraco_text/default.nix b/pkgs/development/python-modules/jaraco_text/default.nix
index 3126ab999674..32e8aa23aeb4 100644
--- a/pkgs/development/python-modules/jaraco_text/default.nix
+++ b/pkgs/development/python-modules/jaraco_text/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "jaraco.text";
-  version = "3.5.0";
+  version = "3.5.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f07f1076814a17a98eb915948b9a0dc71b1891c833588066ec1feb04ea4389b1";
+    sha256 = "ede4e9103443b62b3d1d193257dfb85aab7c69a6cef78a0887d64bb307a03bc3";
   };
 
   pythonNamespaces = [ "jaraco" ];
diff --git a/pkgs/development/python-modules/jeepney/default.nix b/pkgs/development/python-modules/jeepney/default.nix
index 2acf0361bcbc..3079f152e444 100644
--- a/pkgs/development/python-modules/jeepney/default.nix
+++ b/pkgs/development/python-modules/jeepney/default.nix
@@ -2,6 +2,7 @@
 , buildPythonPackage
 , fetchPypi
 , pythonOlder
+, async-timeout
 , dbus
 , pytest
 , pytest-trio
@@ -12,16 +13,17 @@
 
 buildPythonPackage rec {
   pname = "jeepney";
-  version = "0.7.0";
+  version = "0.7.1";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1237cd64c8f7ac3aa4b3f332c4d0fb4a8216f39eaa662ec904302d4d77de5a54";
+    sha256 = "fa9e232dfa0c498bd0b8a3a73b8d8a31978304dcef0515adc859d4e096f96f4f";
   };
 
   checkInputs = [
+    async-timeout
     dbus
     pytest
     pytest-trio
diff --git a/pkgs/development/python-modules/jira/default.nix b/pkgs/development/python-modules/jira/default.nix
index a3f790abfc51..c7d8207aa3d9 100644
--- a/pkgs/development/python-modules/jira/default.nix
+++ b/pkgs/development/python-modules/jira/default.nix
@@ -1,34 +1,56 @@
-{ lib, buildPythonPackage, fetchPypi, isPy3k
-, pytest, pytest-runner, pbr, glibcLocales , pytest-cov
-, requests, requests_oauthlib, requests-toolbelt, defusedxml
-, ipython
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, defusedxml
+, flaky
+, keyring
+, requests-mock
+, requests_oauthlib
+, requests-toolbelt
+, setuptools-scm
+, setuptools-scm-git-archive
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "jira";
-  version = "2.0.0";
+  version = "3.0.1";
 
-  PBR_VERSION = version;
-
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "e2a94adff98e45b29ded030adc76103eab34fa7d4d57303f211f572bedba0e93";
+  src = fetchFromGitHub {
+    owner = "pycontribs";
+    repo = pname;
+    rev = version;
+    sha256 = "sha256-hAUAzkHPXFDlKEom+dkzr8GQ+sqK2Ci1/k+QuSNvifE=";
   };
 
-  buildInputs = [ glibcLocales pytest pytest-cov pytest-runner pbr ];
-  propagatedBuildInputs = [ requests requests_oauthlib requests-toolbelt defusedxml pbr ipython ];
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "--cov-report=xml --cov jira" ""
+  '';
+
+  nativeBuildInputs = [ setuptools-scm setuptools-scm-git-archive ];
+
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
+
+  propagatedBuildInputs = [
+    defusedxml
+    keyring
+    requests_oauthlib
+    requests-toolbelt
+  ];
+
+  checkInputs = [
+    flaky
+    pytestCheckHook
+    requests-mock
+  ];
 
   # impure tests because of connectivity attempts to jira servers
   doCheck = false;
 
-  patches = [ ./sphinx-fix.patch ];
-
-  LC_ALL = "en_US.utf8";
-
-  disabled = !isPy3k;
-
   meta = with lib; {
     description = "This library eases the use of the JIRA REST API from Python.";
+    homepage = "https://github.com/pycontribs/jira";
     license = licenses.bsd2;
     maintainers = with maintainers; [ globin ];
   };
diff --git a/pkgs/development/python-modules/jira/sphinx-fix.patch b/pkgs/development/python-modules/jira/sphinx-fix.patch
deleted file mode 100644
index ccc47ac4b9cf..000000000000
--- a/pkgs/development/python-modules/jira/sphinx-fix.patch
+++ /dev/null
@@ -1,11 +0,0 @@
-diff --git a/setup.py b/setup.py
-index c49a24d..31aeec2 100644
---- a/setup.py
-+++ b/setup.py
-@@ -11,5 +11,5 @@ except ImportError:
- 
- 
- setuptools.setup(
--    setup_requires=['pbr>=3.0.0', 'setuptools>=17.1', 'pytest-runner', 'sphinx>=1.6.5'],
-+    setup_requires=['pbr>=3.0.0', 'setuptools>=17.1', 'pytest-runner'],
-     pbr=True)
diff --git a/pkgs/development/python-modules/jupyter-repo2docker/default.nix b/pkgs/development/python-modules/jupyter-repo2docker/default.nix
index 1b352f1e24c9..f4eb9190aa4b 100644
--- a/pkgs/development/python-modules/jupyter-repo2docker/default.nix
+++ b/pkgs/development/python-modules/jupyter-repo2docker/default.nix
@@ -12,13 +12,13 @@
 }:
 
 buildPythonPackage rec {
-  version = "2021.3.0";
+  version = "2021.8.0";
   pname = "jupyter-repo2docker";
   disabled = pythonOlder "3.4";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "42e0cf67181bdd03b54dabde695befec0586ed68a4ec1240104e209997d776c4";
+    sha256 = "9d1b3c3ec7944ea6b0a234d6fa77293a2d1ed1c080eba8466aba94f811b3465d";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/jupyter_client/default.nix b/pkgs/development/python-modules/jupyter_client/default.nix
index fbc37c3f581b..e30b3cb63a71 100644
--- a/pkgs/development/python-modules/jupyter_client/default.nix
+++ b/pkgs/development/python-modules/jupyter_client/default.nix
@@ -1,30 +1,34 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, traitlets
+, entrypoints
 , jupyter_core
-, pyzmq
+, nest-asyncio
 , python-dateutil
+, pyzmq
+, tornado
+, traitlets
 , isPyPy
 , py
-, tornado
 }:
 
 buildPythonPackage rec {
   pname = "jupyter_client";
-  version = "6.1.12";
+  version = "7.0.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c4bca1d0846186ca8be97f4d2fa6d2bae889cce4892a167ffa1ba6bd1f73e782";
+    sha256 = "0c6cabd07e003a2e9692394bf1ae794188ad17d2e250ed747232d7a473aa772c";
   };
 
   propagatedBuildInputs = [
-    traitlets
+    entrypoints
     jupyter_core
-    pyzmq
+    nest-asyncio
     python-dateutil
+    pyzmq
     tornado
+    traitlets
   ] ++ lib.optional isPyPy py;
 
   # Circular dependency with ipykernel
diff --git a/pkgs/development/python-modules/jupyter_server/default.nix b/pkgs/development/python-modules/jupyter_server/default.nix
index 72e1540e0781..3150235fcc7a 100644
--- a/pkgs/development/python-modules/jupyter_server/default.nix
+++ b/pkgs/development/python-modules/jupyter_server/default.nix
@@ -25,12 +25,12 @@
 
 buildPythonPackage rec {
   pname = "jupyter_server";
-  version = "1.8.0";
+  version = "1.10.2";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8f0c75e0a577536125ad62a442ebb7cf02746f1a69d907e8a273c6225d281237";
+    sha256 = "d3a3b68ebc6d7bfee1097f1712cf7709ee39c92379da2cc08724515bb85e72bf";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/jupyterlab-git/default.nix b/pkgs/development/python-modules/jupyterlab-git/default.nix
index 67769e24b328..dbff1660b1cc 100644
--- a/pkgs/development/python-modules/jupyterlab-git/default.nix
+++ b/pkgs/development/python-modules/jupyterlab-git/default.nix
@@ -10,12 +10,12 @@
 
 buildPythonPackage rec {
   pname = "jupyterlab_git";
-  version = "0.30.1";
+  version = "0.32.2";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "f44a33cf59b424e0b5ff984b18eae33e45dab1ef9dc1901b1dd23f9adff15df2";
+    sha256 = "4c5743a05150ed7736e028aac15787a66735f160e9ae198dacc5a4bd1a727ce2";
   };
 
   propagatedBuildInputs = [ notebook nbdime git ];
diff --git a/pkgs/development/python-modules/jupyterlab/default.nix b/pkgs/development/python-modules/jupyterlab/default.nix
index 6264bbb5c44e..21255bba94f2 100644
--- a/pkgs/development/python-modules/jupyterlab/default.nix
+++ b/pkgs/development/python-modules/jupyterlab/default.nix
@@ -10,12 +10,12 @@
 
 buildPythonPackage rec {
   pname = "jupyterlab";
-  version = "3.1.6";
+  version = "3.1.9";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "6d2ada6a333861f33a1b555d3cb7b07aa9d1ab80f07997b3d0c43878a98c1174";
+    sha256 = "007e42f833e59fd36872d459e45be243d899edbd0e4a98d21388632e4e0d8af7";
   };
 
   nativeBuildInputs = [ jupyter-packaging ];
diff --git a/pkgs/development/python-modules/jupyterlab_server/default.nix b/pkgs/development/python-modules/jupyterlab_server/default.nix
index cca40463b024..2c54fa9da7f7 100644
--- a/pkgs/development/python-modules/jupyterlab_server/default.nix
+++ b/pkgs/development/python-modules/jupyterlab_server/default.nix
@@ -16,12 +16,12 @@
 
 buildPythonPackage rec {
   pname = "jupyterlab_server";
-  version = "2.7.0";
+  version = "2.7.2";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "31457ef564febc42043bc539356c804f6f9144f602e2852150bf0820ed6d7e18";
+    sha256 = "c6c9ae5796ed60c65bccd84503cbd44b9e35b046b8265f24db3cc4d61631fc0d";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/k5test/default.nix b/pkgs/development/python-modules/k5test/default.nix
index 80b62f1e4483..0079194f4fa7 100644
--- a/pkgs/development/python-modules/k5test/default.nix
+++ b/pkgs/development/python-modules/k5test/default.nix
@@ -2,19 +2,21 @@
 , buildPythonPackage
 , fetchPypi
 , substituteAll
-, six
 , krb5Full
 , findutils
 , which
+, pythonOlder
 }:
 
 buildPythonPackage rec {
   pname = "k5test";
-  version = "0.9.2";
+  version = "0.10.0";
+
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1lqp3jgfngyhaxjgj3n230hn90wsylwilh120yjf62h7b1s02mh8";
+    sha256 = "fc5e7e5e286b2f331c1396c33f2a1cd8cf34e78d8d482168a50ffd8576a1455c";
   };
 
   patches = [
@@ -27,17 +29,15 @@ buildPythonPackage rec {
     })
   ];
 
-  propagatedBuildInputs = [
-    six
-  ];
-
   # No tests
   doCheck = false;
 
+  pythonImportsCheck = [ "k5test" ];
+
   meta = with lib; {
     description = "Library for setting up self-contained Kerberos 5 environment";
     homepage = "https://github.com/pythongssapi/k5test";
     license = licenses.mit;
-    maintainers = [ ];
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/k5test/fix-paths.patch b/pkgs/development/python-modules/k5test/fix-paths.patch
index f99835b5f2a3..dc6caf815809 100644
--- a/pkgs/development/python-modules/k5test/fix-paths.patch
+++ b/pkgs/development/python-modules/k5test/fix-paths.patch
@@ -45,42 +45,74 @@ index e289fac..e2f486a 100644
      if options_raw:
          return options_raw.split('\n')
 diff --git a/k5test/realm.py b/k5test/realm.py
-index f57946b..ad78579 100644
+index 161e5ad..9f50049 100644
 --- a/k5test/realm.py
 +++ b/k5test/realm.py
-@@ -181,19 +181,13 @@ class K5Realm(object):
-             return path
+@@ -90,7 +90,7 @@ class K5Realm(metaclass=abc.ABCMeta):
  
-     def _init_paths(self, **paths):
--        self.kdb5_util = self._discover_path('kdb5_util',
--                                             '/usr/sbin/kdb5_util', paths)
--        self.krb5kdc = self._discover_path('krb5kdc',
--                                           '/usr/sbin/krb5kdc', paths)
--        self.kadmin_local = self._discover_path('kadmin_local',
--                                                '/usr/sbin/kadmin.local',
--                                                paths)
--        self.kprop = self._discover_path('kprop', '/usr/sbin/kprop', paths)
--        self.kadmind = self._discover_path('kadmind',
--                                           '/usr/sbin/kadmind', paths)
--
--        self._kinit = self._discover_path('kinit', '/usr/bin/kinit', paths)
--        self._klist = self._discover_path('klist', '/usr/bin/klist', paths)
-+        self.kdb5_util = '@krb5Full@/bin/kdb5_util'
-+        self.krb5kdc = '@krb5Full@/bin/krb5kdc'
-+        self.kadmin_local = '@krb5Full@/bin/kadmin.local'
-+        self.kprop = '@krb5Full@/bin/kprop'
-+        self.kadmind = '@krb5Full@/bin/kadmind'
-+        self._kinit = '@krb5Full@/bin/kinit'
-+        self._klist = '@krb5Full@/bin/klist'
+         if provider_cls == K5Realm:
+             krb5_config = _discover_path('krb5-config',
+-                                         '/usr/bin/krb5-config', kwargs)
++                                         '@krb5Full@/bin/krb5-config', kwargs)
  
-     def _create_conf(self, profile, filename):
-         with open(filename, 'w') as conf_file:
+             try:
+                 krb5_version = subprocess.check_output(
+@@ -101,7 +101,7 @@ class K5Realm(metaclass=abc.ABCMeta):
+                 # macOS output doesn't contain Heimdal
+                 if 'heimdal' in krb5_version.lower() or (
+                         sys.platform == 'darwin' and
+-                        krb5_config == '/usr/bin/krb5-config'):
++                        krb5_config == '@krb5Full@/bin/krb5-config'):
+                     provider_cls = HeimdalRealm
+                 else:
+                     provider_cls = MITRealm
+@@ -434,14 +434,14 @@ class MITRealm(K5Realm):
+     @property
+     def _default_paths(self):
+         return [
+-            ('kdb5_util', 'kdb5_util', '/usr/sbin/kdb5_util'),
+-            ('krb5kdc', 'krb5kdc', '/usr/sbin/kdb5kdc'),
+-            ('kadmin', 'kadmin', '/usr/bin/admin'),
+-            ('kadmin_local', 'kadmin.local', '/usr/sbin/kadmin.local'),
+-            ('kadmind', 'kadmind', '/usr/sbin/kadmind'),
+-            ('kprop', 'kprop', '/usr/sbin/kprop'),
+-            ('_kinit', 'kinit', '/usr/bin/kinit'),
+-            ('_klist', 'klist', '/usr/bin/klist'),
++            ('kdb5_util', 'kdb5_util', '@krb5Full@/bin/kdb5_util'),
++            ('krb5kdc', 'krb5kdc', '@krb5Full@/bin/kdb5kdc'),
++            ('kadmin', 'kadmin', '@krb5Full@/bin/admin'),
++            ('kadmin_local', 'kadmin.local', '@krb5Full@/bin/kadmin.local'),
++            ('kadmind', 'kadmind', '@krb5Full@/bin/kadmind'),
++            ('kprop', 'kprop', '@krb5Full@/bin/kprop'),
++            ('_kinit', 'kinit', '@krb5Full@/bin/kinit'),
++            ('_klist', 'klist', '@krb5Full@/bin/klist'),
+         ]
+ 
+     @property
+@@ -585,12 +585,12 @@ class HeimdalRealm(K5Realm):
+ 
+         return [
+             ('krb5kdc', 'kdc', os.path.join(base, 'kdc')),
+-            ('kadmin', 'kadmin', '/usr/bin/kadmin'),
+-            ('kadmin_local', 'kadmin', '/usr/bin/kadmin'),
++            ('kadmin', 'kadmin', '@krb5Full@/bin/kadmin'),
++            ('kadmin_local', 'kadmin', '@krb5Full@/bin/kadmin'),
+             ('kadmind', 'kadmind', os.path.join(base, 'kadmind')),
+-            ('_kinit', 'kinit', '/usr/bin/kinit'),
+-            ('_klist', 'klist', '/usr/bin/klist'),
+-            ('_ktutil', 'ktutil', '/usr/bin/ktutil'),
++            ('_kinit', 'kinit', '@krb5Full@/bin/kinit'),
++            ('_klist', 'klist', '@krb5Full@/bin/klist'),
++            ('_ktutil', 'ktutil', '@krb5Full@/bin/ktutil'),
+         ]
+ 
+     @property
 diff --git a/k5test/unit.py b/k5test/unit.py
-index 4ee7f98..543d662 100644
+index 3c64b9e..59da1ab 100644
 --- a/k5test/unit.py
 +++ b/k5test/unit.py
 @@ -38,7 +38,7 @@ _KRB_VERSION = None
- def krb_minversion_test(target_version, problem):
+ def krb_minversion_test(target_version, problem, provider=None):
      global _KRB_VERSION
      if _KRB_VERSION is None:
 -        _KRB_VERSION = _utils.get_output("krb5-config --version")
diff --git a/pkgs/development/python-modules/keyring/default.nix b/pkgs/development/python-modules/keyring/default.nix
index cea38abee395..cf765c06d869 100644
--- a/pkgs/development/python-modules/keyring/default.nix
+++ b/pkgs/development/python-modules/keyring/default.nix
@@ -13,12 +13,12 @@
 
 buildPythonPackage rec {
   pname = "keyring";
-  version = "23.0.1";
+  version = "23.1.0";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "045703609dd3fccfcdb27da201684278823b72af515aedec1a8515719a038cb8";
+    sha256 = "b7e0156667f5dcc73c1f63a518005cd18a4eb23fe77321194fefcc03748b21a4";
   };
 
   nativeBuildInputs = [
@@ -48,6 +48,9 @@ buildPythonPackage rec {
   disabledTests = lib.optionals (stdenv.isDarwin) [
     "test_multiprocess_get"
     "test_multiprocess_get_after_native_get"
+  ] ++ [
+    # E       ValueError: too many values to unpack (expected 1)
+    "test_entry_point"
   ];
 
   disabledTestPaths = [
diff --git a/pkgs/development/python-modules/keyrings-alt/default.nix b/pkgs/development/python-modules/keyrings-alt/default.nix
index abcd04a1d307..a45be02b55b2 100644
--- a/pkgs/development/python-modules/keyrings-alt/default.nix
+++ b/pkgs/development/python-modules/keyrings-alt/default.nix
@@ -1,15 +1,15 @@
 { lib, buildPythonPackage, fetchPypi, pythonOlder, isPy27, six
-, pytest, backports_unittest-mock, keyring, setuptools-scm, toml
+, pytest, backports_unittest-mock, keyring, setuptools-scm
 }:
 
 buildPythonPackage rec {
   pname = "keyrings.alt";
-  version = "4.0.2";
+  version = "4.1.0";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "cc475635099d6edd7e475c5a479e5b4da5e811a3af04495a1e9ada488d16fe25";
+    sha256 = "52ccb61d6f16c10f32f30d38cceef7811ed48e086d73e3bae86f0854352c4ab2";
   };
 
   postPatch = ''
@@ -17,7 +17,7 @@ buildPythonPackage rec {
       --replace "--flake8" ""
   '';
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
   propagatedBuildInputs = [ six ];
 
   checkInputs = [ pytest keyring ] ++ lib.optional (pythonOlder "3.3") backports_unittest-mock;
diff --git a/pkgs/development/python-modules/kiwisolver/default.nix b/pkgs/development/python-modules/kiwisolver/default.nix
index 2b157494f919..e5649c58e465 100644
--- a/pkgs/development/python-modules/kiwisolver/default.nix
+++ b/pkgs/development/python-modules/kiwisolver/default.nix
@@ -8,11 +8,11 @@
 
 buildPythonPackage rec {
   pname = "kiwisolver";
-  version = "1.3.1";
+  version = "1.3.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "950a199911a8d94683a6b10321f9345d5a3a8433ec58b217ace979e18f16e248";
+    sha256 = "fc4453705b81d03568d5b808ad8f09c77c47534f6ac2e72e733f9ca4714aa75c";
   };
 
   NIX_CFLAGS_COMPILE = lib.optionalString stdenv.isDarwin "-I${lib.getDev libcxx}/include/c++/v1";
diff --git a/pkgs/development/python-modules/kubernetes/default.nix b/pkgs/development/python-modules/kubernetes/default.nix
index 952527d5cab7..e90f72b0fd25 100644
--- a/pkgs/development/python-modules/kubernetes/default.nix
+++ b/pkgs/development/python-modules/kubernetes/default.nix
@@ -4,7 +4,7 @@
 
 buildPythonPackage rec {
   pname = "kubernetes";
-  version = "12.0.1";
+  version = "18.20.0";
 
   prePatch = ''
     sed -e 's/sphinx>=1.2.1,!=1.3b1,<1.4 # BSD/sphinx/' -i test-requirements.txt
@@ -24,7 +24,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ec52ea01d52e2ec3da255992f7e859f3a76f2bdb51cf65ba8cd71dfc309d8daa";
+    sha256 = "0c72d00e7883375bd39ae99758425f5e6cb86388417cf7cc84305c211b2192cf";
   };
 
   checkInputs = [ isort coverage pytest mock sphinx autopep8 pep8 codecov recommonmark nose ];
diff --git a/pkgs/development/python-modules/labelbox/default.nix b/pkgs/development/python-modules/labelbox/default.nix
index 423185b6f226..5f8057df849d 100644
--- a/pkgs/development/python-modules/labelbox/default.nix
+++ b/pkgs/development/python-modules/labelbox/default.nix
@@ -19,14 +19,14 @@
 
 buildPythonPackage rec {
   pname = "labelbox";
-  version = "2.6.0";
+  version = "3.2.0";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "Labelbox";
     repo = "labelbox-python";
     rev = "V${version}";
-    sha256 = "1lkvc926i3c7isqhaja6k013qgla44cdhvkx76gpdyywq53i9mcb";
+    sha256 = "0vp1lk7hipa4ixa1zcy99r9b5xb1gv54h4i0izx6fv4zf9m0gmw1";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/ldap3/default.nix b/pkgs/development/python-modules/ldap3/default.nix
index 3c613d74e272..cf82b166ec6d 100644
--- a/pkgs/development/python-modules/ldap3/default.nix
+++ b/pkgs/development/python-modules/ldap3/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "ldap3";
-  version = "2.9";
+  version = "2.9.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "18c3ee656a6775b9b0d60f7c6c5b094d878d1d90fc03d56731039f0a4b546a91";
+    sha256 = "f3e7fc4718e3f09dda568b57100095e0ce58633bcabbed8667ce3f8fbaa4229f";
   };
 
   propagatedBuildInputs = [ pyasn1 ];
diff --git a/pkgs/development/python-modules/lexid/default.nix b/pkgs/development/python-modules/lexid/default.nix
index 4307d52d8913..400643383773 100644
--- a/pkgs/development/python-modules/lexid/default.nix
+++ b/pkgs/development/python-modules/lexid/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "lexid";
-  version = "2020.1005";
+  version = "2021.1006";
   disabled = pythonOlder "3.6";
   src = fetchPypi {
     inherit pname version;
-    sha256 = "52333a2b9ebd14aa0dfeb33de72bd159c2dc31adb9c59cddfc486e2b69bfdcd1";
+    sha256 = "509a3a4cc926d3dbf22b203b18a4c66c25e6473fb7c0e0d30374533ac28bafe5";
   };
 
   propagatedBuildInputs = [ click ];
diff --git a/pkgs/development/python-modules/libarchive-c/default.nix b/pkgs/development/python-modules/libarchive-c/default.nix
index 73d99afda674..48262398fcbf 100644
--- a/pkgs/development/python-modules/libarchive-c/default.nix
+++ b/pkgs/development/python-modules/libarchive-c/default.nix
@@ -1,23 +1,26 @@
-{ lib, stdenv
+{ lib
+, stdenv
 , buildPythonPackage
-, fetchPypi
-, pytest
-, glibcLocales
+, pythonAtLeast
+, fetchFromGitHub
 , libarchive
+, glibcLocales
 , mock
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "libarchive-c";
-  version = "2.9";
+  version = "3.1";
+  format = "setuptools";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "9919344cec203f5db6596a29b5bc26b07ba9662925a05e24980b84709232ef60";
+  src = fetchFromGitHub {
+    owner = "Changaco";
+    repo = "python-${pname}";
+    rev = version;
+    sha256 = "1z4lqy9zlzymshzrcldsc9ipys2l7grqg4yff6ndl6dgbfb0g4jb";
   };
 
-  checkInputs = [ mock pytest glibcLocales ];
-
   LC_ALL="en_US.UTF-8";
 
   postPatch = ''
@@ -25,9 +28,20 @@ buildPythonPackage rec {
       "find_library('archive')" "'${libarchive.lib}/lib/libarchive${stdenv.hostPlatform.extensions.sharedLibrary}'"
   '';
 
-  checkPhase = ''
-    py.test tests -k 'not test_check_archiveentry_with_unicode_entries_and_name_zip and not test_check_archiveentry_using_python_testtar'
-  '';
+  pythonImportsCheck = [
+    "libarchive"
+  ];
+
+  checkInputs = [
+    glibcLocales
+    mock
+    pytestCheckHook
+  ];
+
+  disabledTests = lib.optionals (pythonAtLeast "3.9") [
+    # causes python3.9 to segfault
+    "test_custom_writer_and_stream_reader"
+  ];
 
   meta = with lib; {
     homepage = "https://github.com/Changaco/python-libarchive-c";
diff --git a/pkgs/development/python-modules/libcst/default.nix b/pkgs/development/python-modules/libcst/default.nix
index 5a1ef3b7f737..5b950ab57397 100644
--- a/pkgs/development/python-modules/libcst/default.nix
+++ b/pkgs/development/python-modules/libcst/default.nix
@@ -15,7 +15,7 @@
 
 buildPythonPackage rec {
   pname = "libcst";
-  version = "0.3.19";
+  version = "0.3.20";
   disabled = pythonOlder "3.6";
 
   # Some files for tests missing from PyPi
@@ -24,7 +24,7 @@ buildPythonPackage rec {
     owner = "instagram";
     repo = pname;
     rev = "v${version}";
-    sha256 = "012g1hyaj015k2sf38a7jnpzjic0f8j97ar84d0f00w2ifzwx4ma";
+    sha256 = "063bl21gyyd25i2v0j6kz29cxxdfhng2nins4i2qblmac90f2nqy";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/llvmlite/default.nix b/pkgs/development/python-modules/llvmlite/default.nix
index c7d2221a22e2..e3b9e3bb7c8a 100644
--- a/pkgs/development/python-modules/llvmlite/default.nix
+++ b/pkgs/development/python-modules/llvmlite/default.nix
@@ -12,17 +12,17 @@
 
 buildPythonPackage rec {
   pname = "llvmlite";
-  version = "0.36.0";
+  version = "0.37.0";
 
   disabled = isPyPy || !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "765128fdf5f149ed0b889ffbe2b05eb1717f8e20a5c87fa2b4018fbcce0fcfc9";
+    sha256 = "6392b870cd018ec0c645d6bbb918d6aa0eeca8c62674baaee30862d6b6865b15";
   };
 
   nativeBuildInputs = [ llvm ];
-  propagatedBuildInputs = [ ] ++ lib.optional (pythonOlder "3.4") enum34;
+  propagatedBuildInputs = lib.optional (pythonOlder "3.4") enum34;
 
   # Disable static linking
   # https://github.com/numba/llvmlite/issues/93
@@ -31,10 +31,12 @@ buildPythonPackage rec {
 
     substituteInPlace llvmlite/tests/test_binding.py --replace "test_linux" "nope"
   '';
+
   # Set directory containing llvm-config binary
   preConfigure = ''
     export LLVM_CONFIG=${llvm.dev}/bin/llvm-config
   '';
+
   checkPhase = ''
     ${python.executable} runtests.py
   '';
diff --git a/pkgs/development/python-modules/marisa-trie/default.nix b/pkgs/development/python-modules/marisa-trie/default.nix
index ade031409b41..4daa619acc4f 100644
--- a/pkgs/development/python-modules/marisa-trie/default.nix
+++ b/pkgs/development/python-modules/marisa-trie/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "marisa-trie";
-  version = "0.7.5";
+  version = "0.7.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c73bc25d868e8c4ea7aa7f1e19892db07bba2463351269b05340ccfa06eb2baf";
+    sha256 = "bbeafb7d92839dc221365340e79d012cb50ee48a1f3f30dd916eb35a8b93db00";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/markdown-it-py/default.nix b/pkgs/development/python-modules/markdown-it-py/default.nix
index 8d75139dddcb..8ed57f3ff031 100644
--- a/pkgs/development/python-modules/markdown-it-py/default.nix
+++ b/pkgs/development/python-modules/markdown-it-py/default.nix
@@ -1,7 +1,6 @@
 { lib
 , buildPythonPackage
 , fetchFromGitHub
-, fetchpatch
 , pytestCheckHook
 , pythonOlder
 , attrs
@@ -14,7 +13,7 @@
 
 buildPythonPackage rec {
   pname = "markdown-it-py";
-  version = "1.0.0";
+  version = "1.1.0";
   format = "pyproject";
 
   disabled = pythonOlder "3.6";
@@ -23,18 +22,9 @@ buildPythonPackage rec {
     owner = "executablebooks";
     repo = pname;
     rev = "v${version}";
-    hash = "sha256-GA7P2I8N+i2ISsVgx58zyhrfKMcZ7pL4X9T/trbsr1Y=";
+    sha256 = "0h7rn3rcqfwmnqs97qczwkw9w5g4df8bgn6sw7k149svfqgrkf56";
   };
 
-  patches = [
-    (fetchpatch {
-      # :arrow_up: UPGRADE: attrs -> v21 (#165)
-      # https://github.com/executablebooks/markdown-it-py/pull/165
-      url = "https://github.com/executablebooks/markdown-it-py/commit/78381ffe1a651741594dc93e693b761422512fa2.patch";
-      sha256 = "1kxhblpi4sycrs3rv50achr8g0wlgq33abg2acra26l736hlsya1";
-    })
-  ];
-
   propagatedBuildInputs = [ attrs linkify-it-py ]
     ++ lib.optional (pythonOlder "3.8") typing-extensions;
 
diff --git a/pkgs/development/python-modules/marshmallow-oneofschema/default.nix b/pkgs/development/python-modules/marshmallow-oneofschema/default.nix
index 343c5952a434..a4b15ce9a544 100644
--- a/pkgs/development/python-modules/marshmallow-oneofschema/default.nix
+++ b/pkgs/development/python-modules/marshmallow-oneofschema/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "marshmallow-oneofschema";
-  version = "2.1.0";
+  version = "3.0.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0s0yr7nv06sfgxglghl2vq74g3m49j60k1hi2qzfsv4bj8hvs35k";
+    sha256 = "62cd2099b29188c92493c2940ee79d1bf2f2619a71721664e5a98ec2faa58237";
   };
 
   propagatedBuildInputs = [ marshmallow setuptools ];
diff --git a/pkgs/development/python-modules/mattermostdriver/default.nix b/pkgs/development/python-modules/mattermostdriver/default.nix
index 7d9421b5d949..6a0be0696063 100644
--- a/pkgs/development/python-modules/mattermostdriver/default.nix
+++ b/pkgs/development/python-modules/mattermostdriver/default.nix
@@ -8,13 +8,13 @@
 
 buildPythonPackage rec {
   pname = "mattermostdriver";
-  version = "7.3.0";
+  version = "7.3.1";
 
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "17jqcpa1xd9n7bf4d5l7wmscls34kymv27gi17pyyfjxbwk5gsga";
+    sha256 = "bf629c4b8f825bd7196208aa93995ac5077bd60939ba67cca314a7f13c1dbcea";
   };
 
   propagatedBuildInputs = [ websockets requests ];
diff --git a/pkgs/development/python-modules/mautrix/default.nix b/pkgs/development/python-modules/mautrix/default.nix
index f0005eef61bf..1b8bcb293892 100644
--- a/pkgs/development/python-modules/mautrix/default.nix
+++ b/pkgs/development/python-modules/mautrix/default.nix
@@ -4,11 +4,11 @@
 
 buildPythonPackage rec {
   pname = "mautrix";
-  version = "0.10.5";
+  version = "0.10.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b7d52d72a9739963b6d39d5e58ef367c00490a90cf7795f23c8b2e2c140c8882";
+    sha256 = "2738370469f8ce27efc37aa6e17319a4149246c9a0da822c8d81d948f0c7e1a7";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/minidump/default.nix b/pkgs/development/python-modules/minidump/default.nix
index 6c00ad650bb5..589b7e351c1e 100644
--- a/pkgs/development/python-modules/minidump/default.nix
+++ b/pkgs/development/python-modules/minidump/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "minidump";
-  version = "0.0.18";
+  version = "0.0.19";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-uf4KZc9C1gWRgHu4ttk1fpL2pG8oUb79uvCIlHItB/8=";
+    sha256 = "67b3327cb96e319633653a353c6281703772335dc84797d6fdce7daf0b3be077";
   };
 
   # Upstream doesn't have tests
diff --git a/pkgs/development/python-modules/mitmproxy/default.nix b/pkgs/development/python-modules/mitmproxy/default.nix
index e9c12548269f..a6638fc6ff49 100644
--- a/pkgs/development/python-modules/mitmproxy/default.nix
+++ b/pkgs/development/python-modules/mitmproxy/default.nix
@@ -45,14 +45,14 @@
 
 buildPythonPackage rec {
   pname = "mitmproxy";
-  version = "6.0.2";
+  version = "7.0.2";
   disabled = pythonOlder "3.8";
 
   src = fetchFromGitHub {
     owner = pname;
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-FyIZKFQtf6qvwo4+NzPa/KOmBCcdGJ3jCqxz26+S2e4=";
+    sha256 = "0y5zsay9b6xgibs6m4gckw63jip35vsdfajsh1nw2zcb2xs1a7qs";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/mkl-service/default.nix b/pkgs/development/python-modules/mkl-service/default.nix
index c54da3055e7c..be0ac454ee98 100644
--- a/pkgs/development/python-modules/mkl-service/default.nix
+++ b/pkgs/development/python-modules/mkl-service/default.nix
@@ -2,13 +2,13 @@
 
 buildPythonPackage rec {
   pname = "mkl-service";
-  version = "2.4.0";
+  version = "2.4.0.post1";
 
   src = fetchFromGitHub {
     owner = "IntelPython";
     repo = "mkl-service";
     rev = "v${version}";
-    sha256 = "1x8j0ij582dyhay0gaqq45a2jz1m4fr8xw0v65ngviajj3cxmcpb";
+    sha256 = "0ysjn8z1hkscb4cycbrvcb93r04w5793yylsy40h5dvjd04ns5jc";
   };
 
   MKLROOT = mkl;
diff --git a/pkgs/development/python-modules/mlflow/default.nix b/pkgs/development/python-modules/mlflow/default.nix
index 2940c111e5dc..b50d98513a2f 100644
--- a/pkgs/development/python-modules/mlflow/default.nix
+++ b/pkgs/development/python-modules/mlflow/default.nix
@@ -25,12 +25,12 @@
 
 buildPythonPackage rec {
   pname = "mlflow";
-  version = "1.18.0";
+  version = "1.20.1";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8942089589d08c05c8a7fc66828c02a9233be462c421881b50bc2a0b183dfdbe";
+    sha256 = "71764443c4942f181fee2d5bf44dd74a0507bcc5b62a1f1e08079d1f40a15fc0";
   };
 
   # run into https://stackoverflow.com/questions/51203641/attributeerror-module-alembic-context-has-no-attribute-config
diff --git a/pkgs/development/python-modules/mne-python/default.nix b/pkgs/development/python-modules/mne-python/default.nix
index 2dfe06d51770..912c2c52ea8e 100644
--- a/pkgs/development/python-modules/mne-python/default.nix
+++ b/pkgs/development/python-modules/mne-python/default.nix
@@ -16,7 +16,7 @@
 
 buildPythonPackage rec {
   pname = "mne-python";
-  version = "0.23.0";
+  version = "0.23.3";
 
   disabled = isPy27;
 
@@ -25,7 +25,7 @@ buildPythonPackage rec {
     owner = "mne-tools";
     repo = pname;
     rev = "v${version}";
-    sha256 = "02fcnfsrc6sccv6x2rnx86g0zw0ivk5s8gx230g6pxfg3lap6knv";
+    sha256 = "1pil4vy4grg49i5xcrqmi43vf40lk5p4sbj5bl0fjixkklavwmhj";
   };
 
   propagatedBuildInputs = [ numpy scipy ];
diff --git a/pkgs/development/python-modules/mocket/default.nix b/pkgs/development/python-modules/mocket/default.nix
index 73a3b07a64c3..f8ff484046bb 100644
--- a/pkgs/development/python-modules/mocket/default.nix
+++ b/pkgs/development/python-modules/mocket/default.nix
@@ -19,12 +19,12 @@
 
 buildPythonPackage rec {
   pname = "mocket";
-  version = "3.9.42";
+  version = "3.9.44";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1vvlbnbypd4z1pjlvhwhd89fn0mis5acfx4v25f1mfl04k63ffah";
+    sha256 = "sha256-oeDYzhSzUXxtYhcLjXAmsi1v9vY5qCE/U9YOYxdQxrg=";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/monotonic/default.nix b/pkgs/development/python-modules/monotonic/default.nix
index e93bf206edaa..d775d5157191 100644
--- a/pkgs/development/python-modules/monotonic/default.nix
+++ b/pkgs/development/python-modules/monotonic/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "monotonic";
-  version = "1.5";
+  version = "1.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "23953d55076df038541e648a53676fb24980f7a1be290cdda21300b3bc21dfb0";
+    sha256 = "3a55207bcfed53ddd5c5bae174524062935efed17792e9de2ad0205ce9ad63f7";
   };
 
   __propagatedImpureHostDeps = lib.optional stdenv.isDarwin "/usr/lib/libc.dylib";
diff --git a/pkgs/development/python-modules/monty/default.nix b/pkgs/development/python-modules/monty/default.nix
index ff236d9becc4..73325c24d94c 100644
--- a/pkgs/development/python-modules/monty/default.nix
+++ b/pkgs/development/python-modules/monty/default.nix
@@ -5,6 +5,7 @@
 , msgpack
 , pytestCheckHook
 , numpy
+, pandas
 , pydantic
 , pymongo
 , ruamel_yaml
@@ -13,17 +14,21 @@
 
 buildPythonPackage rec {
   pname = "monty";
-  version = "2021.6.10";
+  version = "2021.8.17";
   disabled = pythonOlder "3.5"; # uses type annotations
 
-  # No tests in Pypi
   src = fetchFromGitHub {
     owner = "materialsvirtuallab";
     repo = pname;
     rev = "v${version}";
-    sha256 = "01fhl4pl5gj4ahph4lxcm0fmglh0bjw6jz9ckmgzviasg4l1j6h4";
+    sha256 = "0lg6d0qk6iv476rcn45p5f50kips5g9s709cxddwnk5yrz57c4d0";
   };
 
+  postPatch = ''
+    substituteInPlace tests/test_os.py \
+      --replace 'self.assertEqual("/usr/bin/find", which("/usr/bin/find"))' '#'
+  '';
+
   propagatedBuildInputs = [
     ruamel_yaml
     tqdm
@@ -33,15 +38,11 @@ buildPythonPackage rec {
   checkInputs = [
     pytestCheckHook
     numpy
+    pandas
     pydantic
     pymongo
   ];
 
-  preCheck = ''
-    substituteInPlace tests/test_os.py \
-      --replace 'self.assertEqual("/usr/bin/find", which("/usr/bin/find"))' '#'
-  '';
-
   meta = with lib; {
     description = "Serves as a complement to the Python standard library by providing a suite of tools to solve many common problems";
     longDescription = "
diff --git a/pkgs/development/python-modules/moviepy/default.nix b/pkgs/development/python-modules/moviepy/default.nix
index c3acdbe71ec2..a353816d252e 100644
--- a/pkgs/development/python-modules/moviepy/default.nix
+++ b/pkgs/development/python-modules/moviepy/default.nix
@@ -1,7 +1,7 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, pythonAtLeast
+, pythonOlder
 , numpy
 , decorator
 , imageio
@@ -9,44 +9,56 @@
 , proglog
 , requests
 , tqdm
-# Advanced image processing (triples size of output)
+  # Advanced image processing (triples size of output)
 , advancedProcessing ? false
-, opencv3 ? null
-, scikitimage ? null
-, scikit-learn ? null
-, scipy ? null
-, matplotlib ? null
-, youtube-dl ? null
+, opencv3
+, scikitimage
+, scikit-learn
+, scipy
+, matplotlib
+, youtube-dl
 }:
 
-assert advancedProcessing -> (
-  opencv3 != null && scikitimage != null && scikit-learn != null
-  && scipy != null && matplotlib != null && youtube-dl != null);
-
 buildPythonPackage rec {
   pname = "moviepy";
   version = "1.0.3";
 
-  disabled = !(pythonAtLeast "3.4");
+  disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
     sha256 = "2884e35d1788077db3ff89e763c5ba7bfddbd7ae9108c9bc809e7ba58fa433f5";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "decorator>=4.0.2,<5.0" "decorator>=4.0.2,<6.0"
+  '';
+
   # No tests, require network connection
   doCheck = false;
 
   propagatedBuildInputs = [
-    numpy decorator imageio imageio-ffmpeg tqdm requests proglog
-  ] ++ (lib.optionals advancedProcessing [
-    opencv3 scikitimage scikit-learn scipy matplotlib youtube-dl
-  ]);
+    numpy
+    decorator
+    imageio
+    imageio-ffmpeg
+    tqdm
+    requests
+    proglog
+  ] ++ lib.optionals advancedProcessing [
+    opencv3
+    scikitimage
+    scikit-learn
+    scipy
+    matplotlib
+    youtube-dl
+  ];
 
   meta = with lib; {
     description = "Video editing with Python";
     homepage = "https://zulko.github.io/moviepy/";
     license = licenses.mit;
+    maintainers = with maintainers; [ ];
   };
-
 }
diff --git a/pkgs/development/python-modules/mypy-boto3-s3/default.nix b/pkgs/development/python-modules/mypy-boto3-s3/default.nix
index b25e838c96ff..d16d858c22f5 100644
--- a/pkgs/development/python-modules/mypy-boto3-s3/default.nix
+++ b/pkgs/development/python-modules/mypy-boto3-s3/default.nix
@@ -8,12 +8,12 @@
 
 buildPythonPackage rec {
   pname = "mypy-boto3-s3";
-  version = "1.17.97";
+  version = "1.18.29";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "cc12897498213e6aa1530d9f75dadb3916fcd3ce376639560c2fede2c93c51b9";
+    sha256 = "efee8defd50c441f1daec39fe415a81ded16b828678b4606ee8f9dd677bfe53e";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/mypy-protobuf/default.nix b/pkgs/development/python-modules/mypy-protobuf/default.nix
index 6c6ea7b7b1c9..17b0d068c981 100644
--- a/pkgs/development/python-modules/mypy-protobuf/default.nix
+++ b/pkgs/development/python-modules/mypy-protobuf/default.nix
@@ -2,13 +2,13 @@
 
 buildPythonApplication rec {
   pname = "mypy-protobuf";
-  version = "2.4";
+  version = "2.9";
 
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "77e10c476cdd3ee14535c2357e64deac6b1a69f33eb500d795b064acda48c66f";
+    sha256 = "278172935d7121c2f8c7c0a05518dd565a2b76d9e9c4a0a3fcd08a21fa685d43";
   };
 
   propagatedBuildInputs = [ protobuf ];
diff --git a/pkgs/development/python-modules/nbclient/default.nix b/pkgs/development/python-modules/nbclient/default.nix
index 169b89f7b892..3b9986bae048 100644
--- a/pkgs/development/python-modules/nbclient/default.nix
+++ b/pkgs/development/python-modules/nbclient/default.nix
@@ -6,12 +6,12 @@
 
 buildPythonPackage rec {
   pname = "nbclient";
-  version = "0.5.3";
+  version = "0.5.4";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "db17271330c68c8c88d46d72349e24c147bb6f34ec82d8481a8f025c4d26589c";
+    sha256 = "6c8ad36a28edad4562580847f9f1636fe5316a51a323ed85a24a4ad37d4aefce";
   };
 
   inherit doCheck;
diff --git a/pkgs/development/python-modules/nbconvert/default.nix b/pkgs/development/python-modules/nbconvert/default.nix
index 02eda2beb195..67d08f9e50ff 100644
--- a/pkgs/development/python-modules/nbconvert/default.nix
+++ b/pkgs/development/python-modules/nbconvert/default.nix
@@ -23,11 +23,11 @@
 
 buildPythonPackage rec {
   pname = "nbconvert";
-  version = "6.0.7";
+  version = "6.1.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "cbbc13a86dfbd4d1b5dee106539de0795b4db156c894c2c5dc382062bbc29002";
+    sha256 = "d22a8ff202644d31db254d24d52c3a96c82156623fcd7c7f987bba2612303ec9";
   };
 
   # Add $out/share/jupyter to the list of paths that are used to search for
diff --git a/pkgs/development/python-modules/nbdime/default.nix b/pkgs/development/python-modules/nbdime/default.nix
index 96fc94d43e85..a4cbe11fbe7a 100644
--- a/pkgs/development/python-modules/nbdime/default.nix
+++ b/pkgs/development/python-modules/nbdime/default.nix
@@ -24,12 +24,12 @@
 
 buildPythonPackage rec {
   pname = "nbdime";
-  version = "2.1.0";
+  version = "3.1.0";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "4e3efdcfda31c3074cb565cd8e76e2e5421b1c4560c3a00c56f8679dd15590e5";
+    sha256 = "12dc4390b355b26d07ac8d11d50efbcb54bae0ad5842b817131babd2f4567963";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/numba/default.nix b/pkgs/development/python-modules/numba/default.nix
index 74f7d4003dcd..287737900b89 100644
--- a/pkgs/development/python-modules/numba/default.nix
+++ b/pkgs/development/python-modules/numba/default.nix
@@ -12,28 +12,39 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.53.1";
+  version = "0.54.0";
   pname = "numba";
   disabled = pythonOlder "3.6" || pythonAtLeast "3.10";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "9cd4e5216acdc66c4e9dab2dfd22ddb5bef151185c070d4a3cd8e78638aff5b0";
+    sha256 = "bad6bd98ab2e41c34aa9c80b8d9737e07d92a53df4f74d3ada1458b0b516ccff";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "1.21" "1.22"
+
+    substituteInPlace numba/__init__.py \
+      --replace "(1, 20)" "(1, 21)"
+  '';
+
   NIX_CFLAGS_COMPILE = lib.optionalString stdenv.isDarwin "-I${lib.getDev libcxx}/include/c++/v1";
 
   propagatedBuildInputs = [ numpy llvmlite setuptools ];
-  pythonImportsCheck = [ "numba" ];
+
   # Copy test script into $out and run the test suite.
   checkPhase = ''
     ${python.interpreter} -m numba.runtests
   '';
+
   # ImportError: cannot import name '_typeconv'
   doCheck = false;
 
+  pythonImportsCheck = [ "numba" ];
+
   meta =  with lib; {
-    homepage = "http://numba.pydata.org/";
+    homepage = "https://numba.pydata.org/";
     license = licenses.bsd2;
     description = "Compiling Python code using LLVM";
     maintainers = with maintainers; [ fridh ];
diff --git a/pkgs/development/python-modules/numpy/default.nix b/pkgs/development/python-modules/numpy/default.nix
index 9071cec1b03d..60f3bf1091ec 100644
--- a/pkgs/development/python-modules/numpy/default.nix
+++ b/pkgs/development/python-modules/numpy/default.nix
@@ -40,14 +40,14 @@ let
   };
 in buildPythonPackage rec {
   pname = "numpy";
-  version = "1.21.1";
+  version = "1.21.2";
   format = "pyproject.toml";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
     extension = "zip";
-    sha256 = "1za22ggjxzm7drs2vd15s81ad9rlshk4p7pv7mxcbz4acdiszx6z";
+    sha256 = "423216d8afc5923b15df86037c6053bf030d15cc9e3224206ef868c2d63dd6dc";
   };
 
   patches = lib.optionals python.hasDistutilsCxxPatch [
diff --git a/pkgs/development/python-modules/nunavut/default.nix b/pkgs/development/python-modules/nunavut/default.nix
index e8d032e16aba..c628abad8691 100644
--- a/pkgs/development/python-modules/nunavut/default.nix
+++ b/pkgs/development/python-modules/nunavut/default.nix
@@ -7,12 +7,12 @@
 
  buildPythonPackage rec {
   pname = "nunavut";
-  version = "1.2.2";
+  version = "1.4.2";
   disabled = pythonOlder "3.5"; # only python>=3.5 is supported
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "78ab56951172ecd92f9b66dbf9b0ea986dcc6899d462eeef74563ddf33a5a9a5";
+    sha256 = "7238780e42a8d6b7fd3296273c76d35dbebb4520d6778472d556b68b77e2aade";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/openshift/default.nix b/pkgs/development/python-modules/openshift/default.nix
index 052d364982b3..cf604ea38181 100644
--- a/pkgs/development/python-modules/openshift/default.nix
+++ b/pkgs/development/python-modules/openshift/default.nix
@@ -11,11 +11,11 @@
 
 buildPythonPackage rec {
   pname = "openshift";
-  version = "0.12.0";
+  version = "0.12.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-aggRnD4goiZJPp4cngp8AIrJC/V46378cwUSfq8Xml4=";
+    sha256 = "a38957684b17ad0e140a87226249bf26de7267db0c83a6d512b48be258052e1a";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/optuna/default.nix b/pkgs/development/python-modules/optuna/default.nix
index 0b496b5ef0f8..457d796d0b78 100644
--- a/pkgs/development/python-modules/optuna/default.nix
+++ b/pkgs/development/python-modules/optuna/default.nix
@@ -30,14 +30,14 @@
 
 buildPythonPackage rec {
   pname = "optuna";
-  version = "2.8.0";
+  version = "2.9.1";
   disabled = isPy27;
 
   src = fetchFromGitHub {
     owner = "optuna";
     repo = pname;
     rev = "v${version}";
-    sha256 = "1w5vyl36mbk78a5028qa7dlzhavrs1dkx3q8m50ij37pa5cnyksz";
+    sha256 = "1fx80qjrkmnvn2mg9fx26qn3sjlwnwqlmkaf6sqhdw79pn6khlpi";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/pandas/default.nix b/pkgs/development/python-modules/pandas/default.nix
index b7e237a3e3ba..54ce6b3747bf 100644
--- a/pkgs/development/python-modules/pandas/default.nix
+++ b/pkgs/development/python-modules/pandas/default.nix
@@ -33,11 +33,11 @@
 
 buildPythonPackage rec {
   pname = "pandas";
-  version = "1.2.4";
+  version = "1.3.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "649ecab692fade3cbfcf967ff936496b0cfba0af00a55dfaacd82bdda5cb2279";
+    sha256 = "cbcb84d63867af3411fa063af3de64902665bb5b3d40b25b2059e40603594e87";
   };
 
   nativeBuildInputs = [ cython ];
diff --git a/pkgs/development/python-modules/panel/default.nix b/pkgs/development/python-modules/panel/default.nix
index 58ae09af14b9..3f6875f4986f 100644
--- a/pkgs/development/python-modules/panel/default.nix
+++ b/pkgs/development/python-modules/panel/default.nix
@@ -1,6 +1,7 @@
 { lib
 , buildPythonPackage
 , fetchPypi
+, bleach
 , bokeh
 , param
 , pyviz-comms
@@ -12,10 +13,11 @@
 }:
 
 let
-  node = callPackage ./node {};
-in buildPythonPackage rec {
+  node = callPackage ./node { };
+in
+buildPythonPackage rec {
   pname = "panel";
-  version = "0.11.3";
+  version = "0.12.1";
 
   # Don't forget to also update the node packages
   # 1. retrieve the package.json file
@@ -23,7 +25,7 @@ in buildPythonPackage rec {
   # 3. node2nix
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-HpHYHysPE6MRxR0kek5C7sunHMfBsUGdZfxamz2jcLc=";
+    sha256 = "e4898d60abdb82f8a429df7f59dbf8bcaf7e19b3e633555512ceb4ce06678458";
   };
 
   # Since 0.10.0 panel attempts to fetch from the web.
@@ -42,6 +44,7 @@ in buildPythonPackage rec {
   '';
 
   propagatedBuildInputs = [
+    bleach
     bokeh
     param
     pyviz-comms
diff --git a/pkgs/development/python-modules/panel/node/node-env.nix b/pkgs/development/python-modules/panel/node/node-env.nix
index c2b723195b77..21089c4d5459 100644
--- a/pkgs/development/python-modules/panel/node/node-env.nix
+++ b/pkgs/development/python-modules/panel/node/node-env.nix
@@ -391,13 +391,14 @@ let
     , dontStrip ? true
     , unpackPhase ? "true"
     , buildPhase ? "true"
+    , meta ? {}
     , ... }@args:
 
     let
-      extraArgs = removeAttrs args [ "name" "dependencies" "buildInputs" "dontStrip" "dontNpmInstall" "preRebuild" "unpackPhase" "buildPhase" ];
+      extraArgs = removeAttrs args [ "name" "dependencies" "buildInputs" "dontStrip" "dontNpmInstall" "preRebuild" "unpackPhase" "buildPhase" "meta" ];
     in
     stdenv.mkDerivation ({
-      name = "node_${name}-${version}";
+      name = "${name}-${version}";
       buildInputs = [ tarWrapper python nodejs ]
         ++ lib.optional (stdenv.isLinux) utillinux
         ++ lib.optional (stdenv.isDarwin) libtool
@@ -446,6 +447,11 @@ let
         # Run post install hook, if provided
         runHook postInstall
       '';
+
+      meta = {
+        # default to Node.js' platforms
+        platforms = nodejs.meta.platforms;
+      } // meta;
     } // extraArgs);
 
   # Builds a node environment (a node_modules folder and a set of binaries)
diff --git a/pkgs/development/python-modules/panel/node/node-packages.nix b/pkgs/development/python-modules/panel/node/node-packages.nix
index 6e45b64d5c6f..78c7c4ac37d1 100644
--- a/pkgs/development/python-modules/panel/node/node-packages.nix
+++ b/pkgs/development/python-modules/panel/node/node-packages.nix
@@ -4,13 +4,22 @@
 
 let
   sources = {
-    "@bokeh/bokehjs-2.3.1" = {
+    "@babel/runtime-7.15.3" = {
+      name = "_at_babel_slash_runtime";
+      packageName = "@babel/runtime";
+      version = "7.15.3";
+      src = fetchurl {
+        url = "https://registry.npmjs.org/@babel/runtime/-/runtime-7.15.3.tgz";
+        sha512 = "OvwMLqNXkCXSz1kSm58sEsNuhqOx/fKpnUnKnFB5v8uDda5bLNEHNgKPvhDN6IU0LDcnHQ90LlJ0Q6jnyBSIBA==";
+      };
+    };
+    "@bokeh/bokehjs-2.3.3" = {
       name = "_at_bokeh_slash_bokehjs";
       packageName = "@bokeh/bokehjs";
-      version = "2.3.1";
+      version = "2.3.3";
       src = fetchurl {
-        url = "https://registry.npmjs.org/@bokeh/bokehjs/-/bokehjs-2.3.1.tgz";
-        sha512 = "DlNZaqAJFUw38IuSk2TUOcfyiK8Ya3kDRpYt/RgVUftIDW2CWLbBo47kbug9+ykEF49rcnlxcCXhNXzpg4V7gw==";
+        url = "https://registry.npmjs.org/@bokeh/bokehjs/-/bokehjs-2.3.3.tgz";
+        sha512 = "Zev3p5xnS47YsZo5hcGGNUdISH3mkVLKSc6LMVqEIRlnc7Ay79TD9bnApeYh90k0JU1pcMh0gEqHgwVOGPTZ/w==";
       };
     };
     "@bokeh/numbro-1.6.2" = {
@@ -31,13 +40,13 @@ let
         sha512 = "W9tm8Qdw5BrylbZbaVWaQMgLfW/klesnj6J3FnyWpo18hCCOFApccUD8iOnRv7bF6PHlgWk84mW3JT5RSzYKjA==";
       };
     };
-    "@luma.gl/constants-8.4.4" = {
+    "@luma.gl/constants-8.5.5" = {
       name = "_at_luma.gl_slash_constants";
       packageName = "@luma.gl/constants";
-      version = "8.4.4";
+      version = "8.5.5";
       src = fetchurl {
-        url = "https://registry.npmjs.org/@luma.gl/constants/-/constants-8.4.4.tgz";
-        sha512 = "4e58QW6UKXkxiIvWSLoAnTc4cT8nvb0PhLzu1h8KiCuaDT5Vq8csOymcNOy/jhpfcIhHlmT1KwowF5m/DcOlKg==";
+        url = "https://registry.npmjs.org/@luma.gl/constants/-/constants-8.5.5.tgz";
+        sha512 = "3pDC7jFaXliDP7Gvr6pPkorLFBXDnuakNeN87aEYcIM+p3XrkF0rPnDQJEzwScWS9RIopXT858xmL3vG7IYsDw==";
       };
     };
     "@types/debounce-1.2.0" = {
@@ -58,31 +67,31 @@ let
         sha512 = "0L8Mq1+oaIW0oVzGUDbSW+HnTjCNb4CmoIQE5BkoHt/A7x20z0MJ1PnwfH3atty/vbWLGgvJwVu2Mz3SKFiEFw==";
       };
     };
-    "@types/jquery-3.5.5" = {
+    "@types/jquery-3.5.6" = {
       name = "_at_types_slash_jquery";
       packageName = "@types/jquery";
-      version = "3.5.5";
+      version = "3.5.6";
       src = fetchurl {
-        url = "https://registry.npmjs.org/@types/jquery/-/jquery-3.5.5.tgz";
-        sha512 = "6RXU9Xzpc6vxNrS6FPPapN1SxSHgQ336WC6Jj/N8q30OiaBZ00l1GBgeP7usjVZPivSkGUfL1z/WW6TX989M+w==";
+        url = "https://registry.npmjs.org/@types/jquery/-/jquery-3.5.6.tgz";
+        sha512 = "SmgCQRzGPId4MZQKDj9Hqc6kSXFNWZFHpELkyK8AQhf8Zr6HKfCzFv9ZC1Fv3FyQttJZOlap3qYb12h61iZAIg==";
       };
     };
-    "@types/sizzle-2.3.2" = {
+    "@types/sizzle-2.3.3" = {
       name = "_at_types_slash_sizzle";
       packageName = "@types/sizzle";
-      version = "2.3.2";
+      version = "2.3.3";
       src = fetchurl {
-        url = "https://registry.npmjs.org/@types/sizzle/-/sizzle-2.3.2.tgz";
-        sha512 = "7EJYyKTL7tFR8+gDbB6Wwz/arpGa0Mywk1TJbNzKzHtzbwVmY4HR9WqS5VV7dsBUKQmPNr192jHr/VpBluj/hg==";
+        url = "https://registry.npmjs.org/@types/sizzle/-/sizzle-2.3.3.tgz";
+        sha512 = "JYM8x9EGF163bEyhdJBpR2QX1R5naCJHC8ucJylJ3w9/CVBaskdQ8WqBf8MmQrd1kRvp/a4TS8HJ+bxzR7ZJYQ==";
       };
     };
-    "@types/slickgrid-2.1.30" = {
+    "@types/slickgrid-2.1.31" = {
       name = "_at_types_slash_slickgrid";
       packageName = "@types/slickgrid";
-      version = "2.1.30";
+      version = "2.1.31";
       src = fetchurl {
-        url = "https://registry.npmjs.org/@types/slickgrid/-/slickgrid-2.1.30.tgz";
-        sha512 = "9nTqNWD3BtEVK0CP+G+mBtvSrKTfQy3Dg5/al+GdTSVMHFm37UxsHJ1eURwPg7rYu6vc7xU95fGTCKMZbxsD5w==";
+        url = "https://registry.npmjs.org/@types/slickgrid/-/slickgrid-2.1.31.tgz";
+        sha512 = "t/LodOkh8yP+o2jKcHsC0hAjDh1kl4RSFXKWmR9+U5FwXE7VpipqiAkE1W3NnGNA3ni5xnKQJt/CNXurJWTQ6w==";
       };
     };
     "choices.js-9.0.1" = {
@@ -202,13 +211,13 @@ let
         sha1 = "df8c69eef1647923c7157b9ce83840610b02cc39";
       };
     };
-    "ext-1.4.0" = {
+    "ext-1.5.0" = {
       name = "ext";
       packageName = "ext";
-      version = "1.4.0";
+      version = "1.5.0";
       src = fetchurl {
-        url = "https://registry.npmjs.org/ext/-/ext-1.4.0.tgz";
-        sha512 = "Key5NIsUxdqKg3vIsdw9dSuXpPCQ297y6wBjL30edxwPgt2E44WcWBZey/ZvUc6sERLTxKdyCu4gZFmUbk1Q7A==";
+        url = "https://registry.npmjs.org/ext/-/ext-1.5.0.tgz";
+        sha512 = "+ONcYoWj/SoQwUofMr94aGu05Ou4FepKi7N7b+O8T4jVfyIsZQV1/xeS8jpaBzF0csAk0KLXoHCxU7cKYZjo1Q==";
       };
     };
     "fast-deep-equal-2.0.1" = {
@@ -283,13 +292,13 @@ let
         sha1 = "04ef77862cff2bb79d30f7692095930222bf60f1";
       };
     };
-    "htm-3.0.4" = {
+    "htm-3.1.0" = {
       name = "htm";
       packageName = "htm";
-      version = "3.0.4";
+      version = "3.1.0";
       src = fetchurl {
-        url = "https://registry.npmjs.org/htm/-/htm-3.0.4.tgz";
-        sha512 = "VRdvxX3tmrXuT/Ovt59NMp/ORMFi4bceFMDjos1PV4E0mV+5votuID8R60egR9A4U8nLt238R/snlJGz3UYiTQ==";
+        url = "https://registry.npmjs.org/htm/-/htm-3.1.0.tgz";
+        sha512 = "L0s3Sid5r6YwrEvkig14SK3Emmc+kIjlfLhEGn2Vy3bk21JyDEes4MoDsbJk6luaPp8bugErnxPz86ZuAw6e5Q==";
       };
     };
     "jquery-3.6.0" = {
@@ -310,15 +319,6 @@ let
         sha1 = "bcb4045c8dd0539c134bc1488cdd3e768a7a9e51";
       };
     };
-    "js-tokens-4.0.0" = {
-      name = "js-tokens";
-      packageName = "js-tokens";
-      version = "4.0.0";
-      src = fetchurl {
-        url = "https://registry.npmjs.org/js-tokens/-/js-tokens-4.0.0.tgz";
-        sha512 = "RdJUflcE3cUzKiMqQgsCu06FPu9UdIJO0beYbPhHN4k6apgJtifcoCtT9bcxOpYBtpD2kCM6Sbzg4CausW/PKQ==";
-      };
-    };
     "json-formatter-js-2.3.4" = {
       name = "json-formatter-js";
       packageName = "json-formatter-js";
@@ -328,15 +328,6 @@ let
         sha512 = "gmAzYRtPRmYzeAT4T7+t3NhTF89JOAIioCVDddl9YDb3ls3kWcskirafw/MZGJaRhEU6fRimGJHl7CC7gaAI2Q==";
       };
     };
-    "loose-envify-1.4.0" = {
-      name = "loose-envify";
-      packageName = "loose-envify";
-      version = "1.4.0";
-      src = fetchurl {
-        url = "https://registry.npmjs.org/loose-envify/-/loose-envify-1.4.0.tgz";
-        sha512 = "lyuxPGr/Wfhrlem2CL/UcnUc1zcqKAImBDzukY7Y5F/yQiNdko6+fRLevlw1HgMySw7f611UIY408EtxRSoK3Q==";
-      };
-    };
     "mgrs-1.0.0" = {
       name = "mgrs";
       packageName = "mgrs";
@@ -364,31 +355,40 @@ let
         sha512 = "4RtQ1+LHJKesDCNJrXkQcwXAWCrC2aggdLYMstS/G5fEWL+fXZbUA9pwVNHFghMGuFGRATlDLNInRaPeRKzpFQ==";
       };
     };
-    "preact-10.5.13" = {
+    "preact-10.5.14" = {
       name = "preact";
       packageName = "preact";
-      version = "10.5.13";
+      version = "10.5.14";
       src = fetchurl {
-        url = "https://registry.npmjs.org/preact/-/preact-10.5.13.tgz";
-        sha512 = "q/vlKIGNwzTLu+jCcvywgGrt+H/1P/oIRSD6mV4ln3hmlC+Aa34C7yfPI4+5bzW8pONyVXYS7SvXosy2dKKtWQ==";
+        url = "https://registry.npmjs.org/preact/-/preact-10.5.14.tgz";
+        sha512 = "KojoltCrshZ099ksUZ2OQKfbH66uquFoxHSbnwKbTJHeQNvx42EmC7wQVWNuDt6vC5s3nudRHFtKbpY4ijKlaQ==";
       };
     };
-    "proj4-2.7.2" = {
+    "proj4-2.7.5" = {
       name = "proj4";
       packageName = "proj4";
-      version = "2.7.2";
+      version = "2.7.5";
       src = fetchurl {
-        url = "https://registry.npmjs.org/proj4/-/proj4-2.7.2.tgz";
-        sha512 = "x/EboBmIq48a9FED0Z9zWCXkd8VIpXHLsyEXljGtsnzeztC41bFjPjJ0S//wBbNLDnDYRe0e6c3FSSiqMCebDA==";
+        url = "https://registry.npmjs.org/proj4/-/proj4-2.7.5.tgz";
+        sha512 = "5ecXUXbHAfvdhfBQpU7EhUfPCQGUCPmVup/4gnZA3bJY3JcK/xxzm4QQDz1xiXokN6ux65VDczlCtBtKrTSpAQ==";
       };
     };
-    "redux-4.0.5" = {
+    "redux-4.1.1" = {
       name = "redux";
       packageName = "redux";
-      version = "4.0.5";
+      version = "4.1.1";
       src = fetchurl {
-        url = "https://registry.npmjs.org/redux/-/redux-4.0.5.tgz";
-        sha512 = "VSz1uMAH24DM6MF72vcojpYPtrTUu3ByVWfPL1nPfVRb5mZVTve5GnNCUV53QM/BZ66xfWrm0CTWoM+Xlz8V1w==";
+        url = "https://registry.npmjs.org/redux/-/redux-4.1.1.tgz";
+        sha512 = "hZQZdDEM25UY2P493kPYuKqviVwZ58lEmGQNeQ+gXa+U0gYPUBf7NKYazbe3m+bs/DzM/ahN12DbF+NG8i0CWw==";
+      };
+    };
+    "regenerator-runtime-0.13.9" = {
+      name = "regenerator-runtime";
+      packageName = "regenerator-runtime";
+      version = "0.13.9";
+      src = fetchurl {
+        url = "https://registry.npmjs.org/regenerator-runtime/-/regenerator-runtime-0.13.9.tgz";
+        sha512 = "p3VT+cOEgxFsRRA9X4lkI1E+k2/CtnKtU4gcxyaCUreilL/vqI6CdZ3wxVUx3UOUg+gnUOQQcRI7BmSI656MYA==";
       };
     };
     "sprintf-js-1.1.2" = {
@@ -400,15 +400,6 @@ let
         sha512 = "VE0SOVEHCk7Qc8ulkWw3ntAzXuqf7S2lvwQaDLRnUeIEaKNQJzV6BwmLKhOqT61aGhfUMrXeaBk+oDGCzvhcug==";
       };
     };
-    "symbol-observable-1.2.0" = {
-      name = "symbol-observable";
-      packageName = "symbol-observable";
-      version = "1.2.0";
-      src = fetchurl {
-        url = "https://registry.npmjs.org/symbol-observable/-/symbol-observable-1.2.0.tgz";
-        sha512 = "e900nM8RRtGhlV36KGEU9k65K3mPb1WV70OdjfxlG2EAuM1noi/E/BaW/uMhL7bPEssK8QV57vN3esixjUvcXQ==";
-      };
-    };
     "timezone-1.0.23" = {
       name = "timezone";
       packageName = "timezone";
@@ -427,13 +418,13 @@ let
         sha512 = "Xni35NKzjgMrwevysHTCArtLDpPvye8zV/0E4EyYn43P7/7qvQwPh9BGkHewbMulVntbigmcT7rdX3BNo9wRJg==";
       };
     };
-    "tslib-2.2.0" = {
+    "tslib-2.3.1" = {
       name = "tslib";
       packageName = "tslib";
-      version = "2.2.0";
+      version = "2.3.1";
       src = fetchurl {
-        url = "https://registry.npmjs.org/tslib/-/tslib-2.2.0.tgz";
-        sha512 = "gS9GVHRU+RGn5KQM2rllAlR3dU6m7AcpJKdtH8gFvQiC4Otgk98XnmMU+nZenHt/+VhnBPWwgrJsyrdcw6i23w==";
+        url = "https://registry.npmjs.org/tslib/-/tslib-2.3.1.tgz";
+        sha512 = "77EbyPPpMz+FRFRuAFlWMtmgUWGe9UOG2Z25NqCwiIjRhOf5iKGuzSe5P2w1laq+FkRy4p+PCuVkJSGkzTEKVw==";
       };
     };
     "type-1.2.0" = {
@@ -463,35 +454,36 @@ let
         sha1 = "3013e0ea181756306f1609e959cafbc722adb3e9";
       };
     };
-    "wkt-parser-1.2.4" = {
+    "wkt-parser-1.3.1" = {
       name = "wkt-parser";
       packageName = "wkt-parser";
-      version = "1.2.4";
+      version = "1.3.1";
       src = fetchurl {
-        url = "https://registry.npmjs.org/wkt-parser/-/wkt-parser-1.2.4.tgz";
-        sha512 = "ZzKnc7ml/91fOPh5bANBL4vUlWPIYYv11waCtWTkl2TRN+LEmBg60Q1MA8gqV4hEp4MGfSj9JiHz91zw/gTDXg==";
+        url = "https://registry.npmjs.org/wkt-parser/-/wkt-parser-1.3.1.tgz";
+        sha512 = "XK5qV+Y5gsygQfHx2/cS5a7Zxsgleaw8iX5UPC5eOXPc0TgJAu1JB9lr0iYYX3zAnN3p0aNiaN5c+1Bdblxwrg==";
       };
     };
   };
   args = {
     name = "_at_holoviz_slash_panel";
     packageName = "@holoviz/panel";
-    version = "0.11.3";
+    version = "0.12.1";
     src = ./.;
     dependencies = [
-      sources."@bokeh/bokehjs-2.3.1"
+      sources."@babel/runtime-7.15.3"
+      sources."@bokeh/bokehjs-2.3.3"
       sources."@bokeh/numbro-1.6.2"
       (sources."@bokeh/slickgrid-2.4.2702" // {
         dependencies = [
           sources."tslib-1.14.1"
         ];
       })
-      sources."@luma.gl/constants-8.4.4"
+      sources."@luma.gl/constants-8.5.5"
       sources."@types/debounce-1.2.0"
       sources."@types/gl-matrix-2.4.5"
-      sources."@types/jquery-3.5.5"
-      sources."@types/sizzle-2.3.2"
-      sources."@types/slickgrid-2.1.30"
+      sources."@types/jquery-3.5.6"
+      sources."@types/sizzle-2.3.3"
+      sources."@types/slickgrid-2.1.31"
       sources."choices.js-9.0.1"
       sources."d-1.0.1"
       sources."debounce-1.2.1"
@@ -508,7 +500,7 @@ let
       sources."es6-symbol-3.1.3"
       sources."es6-weak-map-2.0.3"
       sources."event-emitter-0.3.5"
-      (sources."ext-1.4.0" // {
+      (sources."ext-1.5.0" // {
         dependencies = [
           sources."type-2.5.0"
         ];
@@ -521,25 +513,23 @@ let
       sources."fuse.js-3.6.1"
       sources."gl-matrix-3.3.0"
       sources."hammerjs-2.0.8"
-      sources."htm-3.0.4"
+      sources."htm-3.1.0"
       sources."jquery-3.6.0"
       sources."jquery-ui-1.12.1"
-      sources."js-tokens-4.0.0"
       sources."json-formatter-js-2.3.4"
-      sources."loose-envify-1.4.0"
       sources."mgrs-1.0.0"
       sources."next-tick-1.0.0"
       sources."nouislider-14.7.0"
-      sources."preact-10.5.13"
-      sources."proj4-2.7.2"
-      sources."redux-4.0.5"
+      sources."preact-10.5.14"
+      sources."proj4-2.7.5"
+      sources."redux-4.1.1"
+      sources."regenerator-runtime-0.13.9"
       sources."sprintf-js-1.1.2"
-      sources."symbol-observable-1.2.0"
       sources."timezone-1.0.23"
-      sources."tslib-2.2.0"
+      sources."tslib-2.3.1"
       sources."type-1.2.0"
       sources."underscore.template-0.1.7"
-      sources."wkt-parser-1.2.4"
+      sources."wkt-parser-1.3.1"
     ];
     buildInputs = globalBuildInputs;
     meta = {
diff --git a/pkgs/development/python-modules/panel/node/package.json b/pkgs/development/python-modules/panel/node/package.json
index f40e3773e23b..dc1d13ab4875 100644
--- a/pkgs/development/python-modules/panel/node/package.json
+++ b/pkgs/development/python-modules/panel/node/package.json
@@ -1,6 +1,6 @@
 {
   "name": "@holoviz/panel",
-  "version": "0.11.1",
+  "version": "0.12.1",
   "description": "A high level dashboarding library for python visualization libraries.",
   "license": "BSD-3-Clause",
   "repository": {
@@ -8,7 +8,7 @@
     "url": "https://github.com/holoviz/panel.git"
   },
   "dependencies": {
-    "@bokeh/bokehjs": "^2.3.0",
+    "@bokeh/bokehjs": "^2.3.3",
     "@luma.gl/constants": "^8.0.3",
     "@types/debounce": "^1.2.0",
     "@types/gl-matrix": "^2.4.5",
diff --git a/pkgs/development/python-modules/paramiko/default.nix b/pkgs/development/python-modules/paramiko/default.nix
index c2237f68524f..88d63f0de93f 100644
--- a/pkgs/development/python-modules/paramiko/default.nix
+++ b/pkgs/development/python-modules/paramiko/default.nix
@@ -6,7 +6,7 @@
 , invoke
 , pynacl
 , pyasn1
-, pytest
+, pytestCheckHook
 , pytest-relaxed
 , mock
 }:
@@ -20,25 +20,21 @@ buildPythonPackage rec {
     sha256 = "7f36f4ba2c0d81d219f4595e35f70d56cc94f9ac40a6acdf51d6ca210ce65035";
   };
 
-  checkInputs = [ invoke pytest mock pytest-relaxed ];
   propagatedBuildInputs = [ bcrypt cryptography pynacl pyasn1 ];
 
-  __darwinAllowLocalNetworking = true;
+  checkInputs = [ invoke pytestCheckHook pytest-relaxed mock ];
 
-  # 2 sftp tests fail (skip for now)
-  # test_config relies on artifacts to be to downloaded
-  # RSA tests don't have valid keys
-  checkPhase = ''
-    pytest tests \
-      --ignore=tests/test_sftp.py \
-      --ignore=tests/test_config.py
-  '';
+  disabledTestPaths = [
+    "tests/test_sftp.py"
+    "tests/test_config.py"
+  ];
+
+  __darwinAllowLocalNetworking = true;
 
   meta = with pkgs.lib; {
     homepage = "https://github.com/paramiko/paramiko/";
     description = "Native Python SSHv2 protocol library";
     license = licenses.lgpl21Plus;
-
     longDescription = ''
       This is a library for making SSH2 connections (client or server).
       Emphasis is on using SSH2 as an alternative to SSL for making secure
diff --git a/pkgs/development/python-modules/pathlib2/default.nix b/pkgs/development/python-modules/pathlib2/default.nix
index b21536060d3a..757ddc7d9746 100644
--- a/pkgs/development/python-modules/pathlib2/default.nix
+++ b/pkgs/development/python-modules/pathlib2/default.nix
@@ -10,11 +10,11 @@
 
 buildPythonPackage rec {
   pname = "pathlib2";
-  version = "2.3.5";
+  version = "2.3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "6cd9a47b597b37cc57de1c05e56fb1a1c9cc9fab04fe78c29acd090418529868";
+    sha256 = "7d8bcb5555003cdf4a8d2872c538faa3a0f5d20630cb360e518ca3b981795e5f";
   };
 
   propagatedBuildInputs = [ six ] ++ lib.optional (pythonOlder "3.5") scandir;
diff --git a/pkgs/development/python-modules/pathspec/default.nix b/pkgs/development/python-modules/pathspec/default.nix
index cd51747d5678..6a0281b756ec 100644
--- a/pkgs/development/python-modules/pathspec/default.nix
+++ b/pkgs/development/python-modules/pathspec/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname   = "pathspec";
-  version = "0.8.1";
+  version = "0.9.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "86379d6b86d75816baba717e64b1a3a3469deb93bb76d613c9ce79edc5cb68fd";
+    sha256 = "e564499435a2673d586f6b2130bb5b95f04a3ba06f81b8f895b651a3c76aabb1";
   };
 
   meta = {
diff --git a/pkgs/development/python-modules/pathy/default.nix b/pkgs/development/python-modules/pathy/default.nix
index d656a752cf55..9108c3656dbd 100644
--- a/pkgs/development/python-modules/pathy/default.nix
+++ b/pkgs/development/python-modules/pathy/default.nix
@@ -12,11 +12,11 @@
 
 buildPythonPackage rec {
   pname = "pathy";
-  version = "0.5.2";
+  version = "0.6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-nb8my/5rkc7thuHnXZHe1Hg8j+sLBlYyJcLHWrrKZ5M=";
+    sha256 = "f83f1eddf77dd86e824143eef8d9adbe0785c3cdd5ec0ed6c0edea3227385048";
   };
 
   propagatedBuildInputs = [ smart-open typer google-cloud-storage ];
diff --git a/pkgs/development/python-modules/pdoc3/default.nix b/pkgs/development/python-modules/pdoc3/default.nix
index 66bed253cb86..1a3996311570 100644
--- a/pkgs/development/python-modules/pdoc3/default.nix
+++ b/pkgs/development/python-modules/pdoc3/default.nix
@@ -8,12 +8,12 @@
 
 buildPythonPackage rec {
   pname = "pdoc3";
-  version = "0.9.2";
+  version = "0.10.0";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "9df5d931f25f353c69c46819a3bd03ef96dd286f2a70bb1b93a23a781f91faa1";
+    sha256 = "5f22e7bcb969006738e1aa4219c75a32f34c2d62d46dc9d2fb2d3e0b0287e4b7";
   };
 
   nativeBuildInputs = [ setuptools-git setuptools-scm ];
diff --git a/pkgs/development/python-modules/phik/default.nix b/pkgs/development/python-modules/phik/default.nix
index b309fb287d80..09a240f4c4a6 100644
--- a/pkgs/development/python-modules/phik/default.nix
+++ b/pkgs/development/python-modules/phik/default.nix
@@ -16,14 +16,14 @@
 
 buildPythonPackage rec {
   pname = "phik";
-  version = "0.10.0";
+  version = "0.12.0";
   format = "wheel";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version format;
     python = "py3";
-    sha256 = "b745313c5ff9d6a3092eefa97f83fa4dbed178c9ce69161b655e95497cb2f38b";
+    sha256 = "57db39d1c74c84a24d0270b63d1c629a5cb975462919895b96a8522ae0678408";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/pkgconfig/default.nix b/pkgs/development/python-modules/pkgconfig/default.nix
index d51a83a05478..fc593e6a48fb 100644
--- a/pkgs/development/python-modules/pkgconfig/default.nix
+++ b/pkgs/development/python-modules/pkgconfig/default.nix
@@ -2,7 +2,7 @@
 
 buildPythonPackage rec {
   pname = "pkgconfig";
-  version = "1.5.4";
+  version = "1.5.5";
 
   inherit (pkg-config)
     setupHooks
@@ -14,7 +14,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "c34503829fd226822fd93c902b1cf275516908a023a24be0a02ba687f3a00399";
+    sha256 = "deb4163ef11f75b520d822d9505c1f462761b4309b1bb713d08689759ea8b899";
   };
 
 
diff --git a/pkgs/development/python-modules/pkginfo/default.nix b/pkgs/development/python-modules/pkginfo/default.nix
index 1b1834e324bb..6bfed6305a8a 100644
--- a/pkgs/development/python-modules/pkginfo/default.nix
+++ b/pkgs/development/python-modules/pkginfo/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "pkginfo";
-  version = "1.7.0";
+  version = "1.7.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "029a70cb45c6171c329dfc890cde0879f8c52d6f3922794796e06f577bb03db4";
+    sha256 = "e7432f81d08adec7297633191bbf0bd47faf13cd8724c3a13250e51d542635bd";
   };
 
   doCheck = false; # I don't know why, but with doCheck = true it fails.
diff --git a/pkgs/development/python-modules/plaid-python/default.nix b/pkgs/development/python-modules/plaid-python/default.nix
index 567fdd42d0d3..b864dedecfe7 100644
--- a/pkgs/development/python-modules/plaid-python/default.nix
+++ b/pkgs/development/python-modules/plaid-python/default.nix
@@ -1,12 +1,12 @@
 { lib, buildPythonPackage, fetchPypi, requests, pytest }:
 
 buildPythonPackage rec {
-  version = "7.4.0";
+  version = "8.1.0";
   pname = "plaid-python";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ab70467116adc110b56eb5a1fdeed726307cc216e04dda46a782aa1a1468ce0e";
+    sha256 = "b1f7b5b58ba3c171bb795352119d54797c8c50877bc376d26cd756de2453e9fd";
   };
 
   checkInputs = [ pytest ];
diff --git a/pkgs/development/python-modules/platformdirs/default.nix b/pkgs/development/python-modules/platformdirs/default.nix
index 90eb35f993a3..f49b8716211e 100644
--- a/pkgs/development/python-modules/platformdirs/default.nix
+++ b/pkgs/development/python-modules/platformdirs/default.nix
@@ -11,14 +11,14 @@
 
 buildPythonPackage rec {
   pname = "platformdirs";
-  version = "2.2.0";
+  version = "2.3.0";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = pname;
     repo = pname;
     rev = version;
-    sha256 = "15f08czqfmxy1y947rlrsjs20jgsy2vc1wqhv4b08b3ijxj0jpqh";
+    sha256 = "sha256-g2DPNN7VxK3EjOXOpSWA4a+PghZ7v2jmjw9+VQyCTBI=";
   };
 
   SETUPTOOLS_SCM_PRETEND_VERSION = version;
diff --git a/pkgs/development/python-modules/plotly/default.nix b/pkgs/development/python-modules/plotly/default.nix
index e2496d6097d9..4b849dd016b8 100644
--- a/pkgs/development/python-modules/plotly/default.nix
+++ b/pkgs/development/python-modules/plotly/default.nix
@@ -1,38 +1,35 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, decorator
-, nbformat
 , pytz
 , requests
-, retrying
 , six
+, tenacity
 }:
 
 buildPythonPackage rec {
   pname = "plotly";
-  version = "4.14.3";
+  version = "5.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "14cxlfl79i9bh3awsf4xgwr14ywm7lnrz2a81s7gp0if77nsx2kx";
+    sha256 = "b6dc306c56e7d5fa7d017718894099b27290b427abf4acad8e5b77fdc3bd32ec";
   };
 
   propagatedBuildInputs = [
-    decorator
-    nbformat
     pytz
     requests
-    retrying
     six
+    tenacity
   ];
 
   # No tests in archive
   doCheck = false;
 
-  meta = {
+  meta = with lib; {
     description = "Python plotting library for collaborative, interactive, publication-quality graphs";
     homepage = "https://plot.ly/python/";
-    license = with lib.licenses; [ mit ];
+    license = with licenses; [ mit ];
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/pluggy/0.nix b/pkgs/development/python-modules/pluggy/0.nix
new file mode 100644
index 000000000000..30fa2e1945b2
--- /dev/null
+++ b/pkgs/development/python-modules/pluggy/0.nix
@@ -0,0 +1,34 @@
+{ buildPythonPackage
+, lib
+, fetchPypi
+, setuptools-scm
+, importlib-metadata
+}:
+
+buildPythonPackage rec {
+  pname = "pluggy";
+  version = "0.13.1";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "15b2acde666561e1298d71b523007ed7364de07029219b604cf808bfa1c765b0";
+  };
+
+  checkPhase = ''
+    py.test
+  '';
+
+  # To prevent infinite recursion with pytest
+  doCheck = false;
+
+  nativeBuildInputs = [ setuptools-scm ];
+
+  propagatedBuildInputs = [ importlib-metadata ];
+
+  meta = {
+    description = "Plugin and hook calling mechanisms for Python";
+    homepage = "https://github.com/pytest-dev/pluggy";
+    license = lib.licenses.mit;
+    maintainers = with lib.maintainers; [ ];
+  };
+}
diff --git a/pkgs/development/python-modules/pluggy/default.nix b/pkgs/development/python-modules/pluggy/default.nix
index 30fa2e1945b2..1a1c23f22d0a 100644
--- a/pkgs/development/python-modules/pluggy/default.nix
+++ b/pkgs/development/python-modules/pluggy/default.nix
@@ -7,11 +7,11 @@
 
 buildPythonPackage rec {
   pname = "pluggy";
-  version = "0.13.1";
+  version = "1.0.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "15b2acde666561e1298d71b523007ed7364de07029219b604cf808bfa1c765b0";
+    sha256 = "4224373bacce55f955a878bf9cfa763c1e360858e330072059e10bad68531159";
   };
 
   checkPhase = ''
diff --git a/pkgs/development/python-modules/poetry-core/default.nix b/pkgs/development/python-modules/poetry-core/default.nix
index 4d8c444dcd20..d5262ee22c47 100644
--- a/pkgs/development/python-modules/poetry-core/default.nix
+++ b/pkgs/development/python-modules/poetry-core/default.nix
@@ -1,7 +1,6 @@
 { lib, buildPythonPackage, fetchFromGitHub, pythonOlder, isPy27
 , importlib-metadata
 , intreehooks
-, isort
 , pathlib2
 , pep517
 , pytest-mock
@@ -13,14 +12,14 @@
 
 buildPythonPackage rec {
   pname = "poetry-core";
-  version = "1.0.3";
+  version = "1.0.4";
   format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "python-poetry";
     repo = pname;
     rev = version;
-    sha256 = "07x0zagf9cfr7g3132jjd5byywkbnzpfbxjfjzpzpj70fqw70qrc";
+    sha256 = "0jgd4d7m5y8ly8n0l9lcq7cjab2y3hifk90f343ksmjzssfd5lg3";
   };
 
   postPatch = lib.optionalString (pythonOlder "3.8") ''
diff --git a/pkgs/development/python-modules/poetry/default.nix b/pkgs/development/python-modules/poetry/default.nix
index 7287797ef331..4b7d35093662 100644
--- a/pkgs/development/python-modules/poetry/default.nix
+++ b/pkgs/development/python-modules/poetry/default.nix
@@ -24,7 +24,7 @@
 
 buildPythonPackage rec {
   pname = "poetry";
-  version = "1.1.7";
+  version = "1.1.8";
   format = "pyproject";
   disabled = isPy27;
 
@@ -32,7 +32,7 @@ buildPythonPackage rec {
     owner = "python-poetry";
     repo = pname;
     rev = version;
-    sha256 = "03cbzjw0sb8rs85iq191ndk9523d6qpymh2nhw5bvcxfvsf9042d";
+    sha256 = "0qcgjb78nj69sppd8146519q9422xxg1bi34gyxy51sjkvd5lxhz";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/prance/default.nix b/pkgs/development/python-modules/prance/default.nix
index 0f18a6ad2072..105fa9e180b7 100644
--- a/pkgs/development/python-modules/prance/default.nix
+++ b/pkgs/development/python-modules/prance/default.nix
@@ -1,51 +1,43 @@
 { lib
 , buildPythonPackage
-, fetchPypi
+, fetchFromGitHub
 , chardet
-, pyyaml
 , requests
+, ruamel_yaml
 , six
 , semver
 , pytestCheckHook
-, pytest-cov
-, pytest-runner
 , openapi-spec-validator
 }:
 
 buildPythonPackage rec {
   pname = "prance";
-  version = "0.21.2";
+  version = "0.21.8.0";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "43ebe3a5b38f0c65c428427004c4d8ce8d7155ddad50610276c89c192680f138";
+  src = fetchFromGitHub {
+    owner = "RonnyPfannschmidt";
+    repo = pname;
+    rev = "v${version}";
+    fetchSubmodules = true;
+    sha256 = "sha256-kGANMHfWwhW3ZBw2ZVCJZR/bV2EPhcydMKhDeDTVwcQ=";
   };
 
-  buildInputs = [
-    pytest-runner
-  ];
-
   propagatedBuildInputs = [
     chardet
-    pyyaml
     requests
+    ruamel_yaml
     six
     semver
   ];
 
   checkInputs = [
     pytestCheckHook
-    pytest-cov
     openapi-spec-validator
   ];
 
   postPatch = ''
-    substituteInPlace setup.py \
-      --replace "tests_require = dev_require," "tests_require = None," \
-      --replace "chardet~=4.0" "" \
-      --replace "semver~=2.13" ""
     substituteInPlace setup.cfg \
-      --replace "--cov-fail-under=90" ""
+      --replace "--cov=prance --cov-report=term-missing --cov-fail-under=90" ""
   '';
 
   # Disable tests that require network
diff --git a/pkgs/development/python-modules/prettytable/default.nix b/pkgs/development/python-modules/prettytable/default.nix
index 23702f8e8cfb..5b3253b31b39 100644
--- a/pkgs/development/python-modules/prettytable/default.nix
+++ b/pkgs/development/python-modules/prettytable/default.nix
@@ -10,11 +10,11 @@
 
 buildPythonPackage rec {
   pname = "prettytable";
-  version = "2.1.0";
+  version = "2.2.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "5882ed9092b391bb8f6e91f59bcdbd748924ff556bb7c634089d5519be87baa0";
+    sha256 = "bd81678c108e6c73d4f1e47cd4283de301faaa6ff6220bcd1d4022038c56b416";
   };
 
   nativeBuildInputs = [ setuptools-scm ];
diff --git a/pkgs/development/python-modules/priority/default.nix b/pkgs/development/python-modules/priority/default.nix
index a699f6ff812f..0f11347a74b8 100644
--- a/pkgs/development/python-modules/priority/default.nix
+++ b/pkgs/development/python-modules/priority/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "priority";
-  version = "1.3.0";
+  version = "2.0.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1gpzn9k9zgks0iw5wdmad9b4dry8haiz2sbp6gycpjkzdld9dhbb";
+    sha256 = "c965d54f1b8d0d0b19479db3924c7c36cf672dbf2aec92d43fbdaf4492ba18c0";
   };
 
   patches = [
diff --git a/pkgs/development/python-modules/psd-tools/default.nix b/pkgs/development/python-modules/psd-tools/default.nix
index 92810ec6a5fb..a642d6ba10d1 100644
--- a/pkgs/development/python-modules/psd-tools/default.nix
+++ b/pkgs/development/python-modules/psd-tools/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "psd-tools";
-  version = "1.9.17";
+  version = "1.9.18";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "d01e11581442dfcc1bd73ac3278bdf1f98e9df8f083a11e5989632ff97322b65";
+    sha256 = "d7e510790512f0bb8150c508531c8681c3d9d0ea63b3ba9b11bbf0952cbd69a8";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/pudb/default.nix b/pkgs/development/python-modules/pudb/default.nix
index af653f260cd3..6df85ca5f089 100644
--- a/pkgs/development/python-modules/pudb/default.nix
+++ b/pkgs/development/python-modules/pudb/default.nix
@@ -8,11 +8,11 @@
 
 buildPythonPackage rec {
   pname = "pudb";
-  version = "2020.1";
+  version = "2021.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "2ef23d3371439f13fffbe7f8b9fc180a19d4183dc9cab204d878d7c7766464bf";
+    sha256 = "309ee82b45a0ffca0bc4c7f521fd3e357589c764f339bdf9dcabb7ad40692d6e";
   };
 
   propagatedBuildInputs = [ pygments urwid ];
diff --git a/pkgs/development/python-modules/py3status/default.nix b/pkgs/development/python-modules/py3status/default.nix
index c8d5068e4e73..e027aaeb294b 100644
--- a/pkgs/development/python-modules/py3status/default.nix
+++ b/pkgs/development/python-modules/py3status/default.nix
@@ -24,11 +24,11 @@
 
 buildPythonPackage rec {
   pname = "py3status";
-  version = "3.38";
+  version = "3.39";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "5660163a91590f320685263a738ab910c7a86346d9c85a68639a19ab83433ce6";
+    sha256 = "d2a11dde0cc82d0eb5e938fe624f223d852ed848c57299ff562827bc4557375f";
   };
 
   doCheck = false;
diff --git a/pkgs/development/python-modules/pyTelegramBotAPI/default.nix b/pkgs/development/python-modules/pyTelegramBotAPI/default.nix
index 58d1d0c694a7..f53038b2e1f6 100644
--- a/pkgs/development/python-modules/pyTelegramBotAPI/default.nix
+++ b/pkgs/development/python-modules/pyTelegramBotAPI/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "pyTelegramBotAPI";
-  version = "3.8.3";
+  version = "4.0.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "afdd887fff42a963f13d09a1f4f5fd24aef08f4b8a594f2ac11e0a29022f1518";
+    sha256 = "6accc4af505ee5b312689eaee1a9bc93cb6ea31a2d905a877c6b47f0888c3dcc";
   };
 
   propagatedBuildInputs = [ requests ];
diff --git a/pkgs/development/python-modules/pybids/default.nix b/pkgs/development/python-modules/pybids/default.nix
index 97187abd7591..daa879a58a0d 100644
--- a/pkgs/development/python-modules/pybids/default.nix
+++ b/pkgs/development/python-modules/pybids/default.nix
@@ -14,12 +14,12 @@
 }:
 
 buildPythonPackage rec {
-  version = "0.13.1";
+  version = "0.13.2";
   pname = "pybids";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-ySDhVX4drotnFiXXDK+9woQ3uigistudpMJYenYl47o=";
+    sha256 = "9692013af3b86b096b5423b88179c6c9b604baff5a6b6f89ba5f40429feb7a3e";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/pybind11/default.nix b/pkgs/development/python-modules/pybind11/default.nix
index 3f825a06cd3c..e6be3f063fef 100644
--- a/pkgs/development/python-modules/pybind11/default.nix
+++ b/pkgs/development/python-modules/pybind11/default.nix
@@ -12,13 +12,13 @@
 
 buildPythonPackage rec {
   pname = "pybind11";
-  version = "2.7.0";
+  version = "2.7.1";
 
   src = fetchFromGitHub {
     owner = "pybind";
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-iEXoNTsfsDq79bKV7A4aOCHr11rT/cqnyLghEtGsaks=";
+    sha256 = "13nq16pxz4vck7jn936ymhm0y0q82hd7kkw0ip7k85cx7wywzbql";
   };
 
   nativeBuildInputs = [ cmake ];
diff --git a/pkgs/development/python-modules/pydeconz/default.nix b/pkgs/development/python-modules/pydeconz/default.nix
index fb0852e2bf11..07fe662f6ec0 100644
--- a/pkgs/development/python-modules/pydeconz/default.nix
+++ b/pkgs/development/python-modules/pydeconz/default.nix
@@ -10,14 +10,14 @@
 
 buildPythonPackage rec {
   pname = "pydeconz";
-  version = "82";
+  version = "83";
   disabled = pythonOlder "3.7";
 
   src = fetchFromGitHub {
     owner = "Kane610";
     repo = "deconz";
     rev = "v${version}";
-    sha256 = "sha256-DdZ6bf+2rMjgjm5aRxcSRI/hN0zfP7uV8PaM40c9IJo=";
+    sha256 = "0azpdgmfby8plsp22hy1ip9vzbnmvf9brmah7hcwkpypg31rb61y";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/pyfaidx/default.nix b/pkgs/development/python-modules/pyfaidx/default.nix
index c179688a8a5b..317691066f47 100644
--- a/pkgs/development/python-modules/pyfaidx/default.nix
+++ b/pkgs/development/python-modules/pyfaidx/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "pyfaidx";
-  version = "0.6.1";
+  version = "0.6.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fae5d2264f62f40e6f37090422a764197de610df36afb5ae827b167d34b8621a";
+    sha256 = "d1258f8d053cba0c90fe329254e8ec59eb28b535b48d9d06e8c7f1d74b8e4531";
   };
 
   propagatedBuildInputs = [ six ];
diff --git a/pkgs/development/python-modules/pyfakefs/default.nix b/pkgs/development/python-modules/pyfakefs/default.nix
index ab4c2f360760..217e552aa0e1 100644
--- a/pkgs/development/python-modules/pyfakefs/default.nix
+++ b/pkgs/development/python-modules/pyfakefs/default.nix
@@ -7,13 +7,13 @@
 }:
 
 buildPythonPackage rec {
-  version = "4.5.0";
+  version = "4.5.1";
   pname = "pyfakefs";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "58b017b3437bbe97803a23755876c6d6aeb5aea37e52cec15e5d86b59c4c7295";
+    sha256 = "002a065dcbf59c2caa039e4fc4ba01d1d636aa63ee9c794d4c9fc01f0e2d6dc0";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/pykka/default.nix b/pkgs/development/python-modules/pykka/default.nix
index 075b607c772e..dfd84fe066d0 100644
--- a/pkgs/development/python-modules/pykka/default.nix
+++ b/pkgs/development/python-modules/pykka/default.nix
@@ -1,21 +1,39 @@
-{ lib, buildPythonPackage, fetchPypi, pytestCheckHook, pytest-mock }:
+{ lib
+, buildPythonPackage
+, pythonOlder
+, fetchFromGitHub
+, poetry-core
+, pytestCheckHook
+, pytest-mock
+}:
 
 buildPythonPackage rec {
-  pname = "Pykka";
-  version = "2.0.3";
+  pname = "pykka";
+  version = "3.0.1";
+  format = "pyproject";
+  disabled = pythonOlder "3.6.1";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "4b9d2363365b3455a0204bf163f09bd351d24b938c618c79d975a9510e128e95";
+  src = fetchFromGitHub {
+    owner = "jodal";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "1h3brgm8y4a9s991y0drkp0vvmxix9f2b49f9w6ibhkhr37gc0lh";
   };
 
-  checkInputs = [ pytestCheckHook pytest-mock ];
+  nativeBuildInputs = [
+    poetry-core
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+    pytest-mock
+  ];
 
   meta = with lib; {
     homepage = "https://www.pykka.org/";
     description = "A Python implementation of the actor model";
     changelog = "https://github.com/jodal/pykka/blob/v${version}/docs/changes.rst";
-    maintainers = [ maintainers.marsam ];
+    maintainers = with maintainers; [ marsam ];
     license = licenses.asl20;
   };
 }
diff --git a/pkgs/development/python-modules/pylint/default.nix b/pkgs/development/python-modules/pylint/default.nix
index ef42bd43239a..2e4953ec7b9b 100644
--- a/pkgs/development/python-modules/pylint/default.nix
+++ b/pkgs/development/python-modules/pylint/default.nix
@@ -1,12 +1,13 @@
 { stdenv
 , lib
 , buildPythonPackage
-, fetchPypi
+, fetchFromGitHub
 , pythonOlder
 , installShellFiles
 , astroid
 , isort
 , mccabe
+, platformdirs
 , toml
 , pytest-benchmark
 , pytest-xdist
@@ -15,13 +16,15 @@
 
 buildPythonPackage rec {
   pname = "pylint";
-  version = "2.7.4";
+  version = "2.10.2";
 
   disabled = pythonOlder "3.6";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "bd38914c7731cdc518634a8d3c5585951302b6e2b6de60fbb3f7a0220e21eeee";
+  src = fetchFromGitHub {
+    owner = "PyCQA";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "sha256-hkrkgUdC5LO1oSPFL6gvIk0zFpMw45gCmnoRbdPZuRs=";
   };
 
   nativeBuildInputs = [
@@ -32,6 +35,7 @@ buildPythonPackage rec {
     astroid
     isort
     mccabe
+    platformdirs
     toml
   ];
 
@@ -58,6 +62,12 @@ buildPythonPackage rec {
     "-n auto"
   ];
 
+  disabledTestPaths = [
+    # tests miss multiple input files
+    # FileNotFoundError: [Errno 2] No such file or directory
+    "tests/pyreverse/test_writer.py"
+  ];
+
   disabledTests = lib.optionals stdenv.isDarwin [
     "test_parallel_execution"
     "test_py3k_jobs_option"
diff --git a/pkgs/development/python-modules/pylitterbot/default.nix b/pkgs/development/python-modules/pylitterbot/default.nix
index 08924d515732..a305a8309a93 100644
--- a/pkgs/development/python-modules/pylitterbot/default.nix
+++ b/pkgs/development/python-modules/pylitterbot/default.nix
@@ -11,14 +11,14 @@
 
 buildPythonPackage rec {
   pname = "pylitterbot";
-  version = "2021.8.0";
+  version = "2021.8.1";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "natekspencer";
     repo = pname;
     rev = version;
-    sha256 = "sha256-Z7/j5ZZd8cOJhY/GfKUcDSJZvmU/TR/KDK60j1eYsik=";
+    sha256 = "sha256-ULaybf2uV8lY9J9EHlszbnLWZJ0QO7y6BQxvdQX+nMU=";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/pymatgen/default.nix b/pkgs/development/python-modules/pymatgen/default.nix
index 364514b6b5d0..56e436e96d2c 100644
--- a/pkgs/development/python-modules/pymatgen/default.nix
+++ b/pkgs/development/python-modules/pymatgen/default.nix
@@ -21,11 +21,11 @@
 
 buildPythonPackage rec {
   pname = "pymatgen";
-  version = "2022.0.11";
+  version = "2022.0.12";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "901d00105142c9added48275188e289e91b3098251ec107aef90acaef3ea6d0d";
+    sha256 = "bad712c883a12d774a8a58c35abc5d582c5e5eafdbb5351dc06ebe98c28bd135";
   };
 
   nativeBuildInputs = [ glibcLocales ];
diff --git a/pkgs/development/python-modules/pymc3/default.nix b/pkgs/development/python-modules/pymc3/default.nix
index e322bb14f7ba..095f3baf97ae 100644
--- a/pkgs/development/python-modules/pymc3/default.nix
+++ b/pkgs/development/python-modules/pymc3/default.nix
@@ -20,12 +20,12 @@
 
 buildPythonPackage rec {
   pname = "pymc3";
-  version = "3.11.2";
+  version = "3.11.4";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "d3b93c8923ae8c8107c5adfd22f7c37fa0849a00a9723e0e0a0ca6afb582d6c3";
+    sha256 = "3b88d1e6c85f7fb8a9b99d6f136ac860672170370ec4146338fdd160c3b3fd3f";
   };
 
   # No need for coverage stats in Nix builds
diff --git a/pkgs/development/python-modules/pynndescent/default.nix b/pkgs/development/python-modules/pynndescent/default.nix
index fa9db26b5e39..7256749f8dec 100644
--- a/pkgs/development/python-modules/pynndescent/default.nix
+++ b/pkgs/development/python-modules/pynndescent/default.nix
@@ -1,43 +1,40 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, nose
+, joblib
+, llvmlite
+, numba
 , scikit-learn
 , scipy
-, numba
-, llvmlite
-, joblib
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
   pname = "pynndescent";
-  version = "0.5.2";
+  version = "0.5.4";
+  format = "setuptools";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0w87c2v0li2rdbx6qfc2lb6y6bxpdy3jwfgzfs1kcr4d1chj5zfr";
+    sha256 = "221124cbad8e3cf3ed421a4089d80ac5a29d3215e76cb49effc1df887533d2a8";
   };
 
   propagatedBuildInputs = [
+    joblib
+    llvmlite
+    numba
     scikit-learn
     scipy
-    numba
-    llvmlite
-    joblib
   ];
 
   checkInputs = [
-    nose
+    pytestCheckHook
   ];
 
-  checkPhase = ''
-    nosetests
-  '';
-
   meta = with lib; {
     description = "Nearest Neighbor Descent";
     homepage = "https://github.com/lmcinnes/pynndescent";
     license = licenses.bsd2;
-    maintainers = [ maintainers.mic92 ];
+    maintainers = with maintainers; [ mic92 ];
   };
 }
diff --git a/pkgs/development/python-modules/pyocr/default.nix b/pkgs/development/python-modules/pyocr/default.nix
index 099c9e237111..df20d3bb6c47 100644
--- a/pkgs/development/python-modules/pyocr/default.nix
+++ b/pkgs/development/python-modules/pyocr/default.nix
@@ -1,6 +1,16 @@
-{ lib, fetchFromGitLab, buildPythonPackage, pillow, setuptools-scm,
-setuptools-scm-git-archive , tesseract, cuneiform, isPy3k, substituteAll,
-pytest, tox }:
+{ lib
+, fetchFromGitLab
+, buildPythonPackage
+, pillow
+, setuptools-scm
+, setuptools-scm-git-archive
+, tesseract
+, cuneiform
+, isPy3k
+, substituteAll
+, pytestCheckHook
+, tox
+}:
 
 buildPythonPackage rec {
   pname = "pyocr";
@@ -17,20 +27,25 @@ buildPythonPackage rec {
     sha256 = "09ab86bmizpv94w3mdvdqkjyyvk1vafw3jqhkiw5xx7p180xn3il";
   };
 
-  patches = [ (substituteAll {
-    src = ./paths.patch;
-    inherit cuneiform tesseract;
-  })
+  patches = [
+    (substituteAll {
+      src = ./paths.patch;
+      inherit cuneiform tesseract;
+    })
   ];
 
-  buildInputs = [ setuptools-scm setuptools-scm-git-archive ];
-  propagatedBuildInputs = [ pillow ];
-  checkInputs = [ pytest tox ];
-  checkPhase = "pytest";
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
 
-  meta = {
+  buildInputs = [ setuptools-scm setuptools-scm-git-archive ];
+
+  propagatedBuildInputs = [ pillow ];
+
+  checkInputs = [ pytestCheckHook ];
+
+  meta = with lib; {
     inherit (src.meta) homepage;
     description = "A Python wrapper for Tesseract and Cuneiform";
-    license = lib.licenses.gpl3Plus;
+    license = licenses.gpl3Plus;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/pyosmium/default.nix b/pkgs/development/python-modules/pyosmium/default.nix
index 6bd360036000..bd6b5d701dda 100644
--- a/pkgs/development/python-modules/pyosmium/default.nix
+++ b/pkgs/development/python-modules/pyosmium/default.nix
@@ -1,10 +1,10 @@
 { lib, buildPythonPackage, fetchFromGitHub, cmake, python
 , libosmium, protozero, boost, expat, bzip2, zlib, pybind11
-, nose, shapely, pythonOlder, isPyPy, lz4 }:
+, nose, shapely, pythonOlder, isPyPy, lz4, requests }:
 
 buildPythonPackage rec {
   pname = "pyosmium";
-  version = "3.1.3";
+  version = "3.2.0";
 
   disabled = pythonOlder "3.4" || isPyPy;
 
@@ -12,11 +12,12 @@ buildPythonPackage rec {
     owner = "osmcode";
     repo = pname;
     rev = "v${version}";
-    sha256 = "11ma8nr7k2ixwwb55fiqvrj5qbmpgkyfk0canz4l0m8b7rcw3qsc";
+    sha256 = "0s9h1blz4vrgcvdiikbpi2d4cy69kg2s8ki4dzampm1s0pa92if5";
   };
 
   nativeBuildInputs = [ cmake ];
   buildInputs = [ libosmium protozero boost expat bzip2 zlib pybind11 lz4 ];
+  propagatedBuildInputs = [ requests ];
 
   preBuild = "cd ..";
 
diff --git a/pkgs/development/python-modules/pyphen/default.nix b/pkgs/development/python-modules/pyphen/default.nix
index 2f573b67838b..74581ba7e33c 100644
--- a/pkgs/development/python-modules/pyphen/default.nix
+++ b/pkgs/development/python-modules/pyphen/default.nix
@@ -1,14 +1,26 @@
-{ lib, buildPythonPackage, fetchPypi }:
+{ lib
+, buildPythonPackage
+, fetchPypi
+, pytestCheckHook
+}:
 
 buildPythonPackage rec {
-  pname = "Pyphen";
-  version = "0.10.0";
+  pname = "pyphen";
+  version = "0.11.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "719b21dfb4b04fbc11cc0f6112418535fe35474021120cccfffc43a25fe63128";
+    sha256 = "e2c3ed82c3a04317df5102addafe89652b0876bc6c6265f5dd4c3efaf02315e8";
   };
 
+  preCheck = ''
+    sed -i '/addopts/d' pyproject.toml
+  '';
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
   meta = with lib; {
     description = "Pure Python module to hyphenate text";
     homepage = "https://github.com/Kozea/Pyphen";
diff --git a/pkgs/development/python-modules/pyramid/default.nix b/pkgs/development/python-modules/pyramid/default.nix
index 95333f746d0c..da9569b7fb73 100644
--- a/pkgs/development/python-modules/pyramid/default.nix
+++ b/pkgs/development/python-modules/pyramid/default.nix
@@ -18,11 +18,11 @@
 
 buildPythonPackage rec {
   pname = "pyramid";
-  version = "1.10.8";
+  version = "2.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b7cd66595bef92f81764b976ddde2b2fa8e4f5f325e02f65f6ec7f3708b29cf6";
+    sha256 = "45431b387587ed0fac6213b54d6e9f0936f0cc85238a8f5af7852fc9484c5c77";
   };
 
   checkInputs = [ webtest zope_component ];
diff --git a/pkgs/development/python-modules/pyrsistent/default.nix b/pkgs/development/python-modules/pyrsistent/default.nix
index 8a6eb47a46c7..75cecc7d7091 100644
--- a/pkgs/development/python-modules/pyrsistent/default.nix
+++ b/pkgs/development/python-modules/pyrsistent/default.nix
@@ -9,13 +9,13 @@
 
 buildPythonPackage rec {
   pname = "pyrsistent";
-  version = "0.17.3";
+  version = "0.18.0";
 
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "2e636185d9eb976a18a8a8e96efce62f2905fea90041958d8cc2a189756ebf3e";
+    sha256 = "773c781216f8c2900b42a7b638d5b517bb134ae1acbebe4d1e8f1f41ea60eb4b";
   };
 
   propagatedBuildInputs = [ six ];
diff --git a/pkgs/development/python-modules/pysatochip/default.nix b/pkgs/development/python-modules/pysatochip/default.nix
index f24571a78cf1..a2e726903554 100644
--- a/pkgs/development/python-modules/pysatochip/default.nix
+++ b/pkgs/development/python-modules/pysatochip/default.nix
@@ -1,17 +1,35 @@
-{ lib, buildPythonPackage, fetchPypi, pyscard, ecdsa, pyaes
-, pythonOlder }:
+{ lib
+, buildPythonPackage
+, fetchPypi
+, certifi
+, cryptography
+, ecdsa
+, pyaes
+, pyopenssl
+, pyscard
+, pythonOlder
+}:
 
 buildPythonPackage rec {
   pname = "pysatochip";
-  version = "0.11.4";
+  version = "0.12.3";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-Jj/zZIS9aXmZ2xdi29Eun7iRIrIk9oBlrtN9+6opIMo=";
+    sha256 = "24db358a65c0402c299c0c62efcfbbfc98e494181cd30d3996949ac667d5b4d4";
   };
 
-  propagatedBuildInputs = [ pyscard ecdsa pyaes ];
+  postPatch = ''
+    substituteInPlace requirements.txt \
+      --replace "cryptography==3.3.2" "cryptography" \
+      --replace "ecdsa==0.15" "ecdsa" \
+      --replace "pyopenssl==20.0.0" "pyopenssl"
+  '';
+
+  propagatedBuildInputs = [ cryptography ecdsa pyaes pyopenssl pyscard ];
+
+  checkInputs = [ certifi ];
 
   pythonImportsCheck = [ "pysatochip" ];
 
diff --git a/pkgs/development/python-modules/pysdl2/default.nix b/pkgs/development/python-modules/pysdl2/default.nix
index be9663245bb5..26aece1afb21 100644
--- a/pkgs/development/python-modules/pysdl2/default.nix
+++ b/pkgs/development/python-modules/pysdl2/default.nix
@@ -2,7 +2,7 @@
 
 buildPythonPackage rec {
   pname = "PySDL2";
-  version = "0.9.7";
+  version = "0.9.8";
   # The tests use OpenGL using find_library, which would have to be
   # patched; also they seem to actually open X windows and test stuff
   # like "screensaver disabling", which would have to be cleverly
@@ -11,7 +11,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e4fcc8aa1108e4917cb56794575ee08c2a3d9c2c52620474e3ecc8538dadf209";
+    sha256 = "4dfa3168e4e4e9301a2cd5904bdcea15e2bf62a1c9abb5d3f92d9122ea22c26e";
   };
 
   # Deliberately not in propagated build inputs; users can decide
diff --git a/pkgs/development/python-modules/pytest-doctestplus/default.nix b/pkgs/development/python-modules/pytest-doctestplus/default.nix
index 01ec38458c9f..8cd73f483fa8 100644
--- a/pkgs/development/python-modules/pytest-doctestplus/default.nix
+++ b/pkgs/development/python-modules/pytest-doctestplus/default.nix
@@ -1,40 +1,50 @@
 { lib
 , buildPythonPackage
 , fetchPypi
-, isPy27
-, six
+, pythonOlder
+, packaging
 , pytest
 , pytestCheckHook
-, numpy
 , setuptools-scm
 }:
 
 buildPythonPackage rec {
   pname = "pytest-doctestplus";
-  version = "0.9.0";
-  disabled = isPy27; # abandoned upstream
+  version = "0.10.1";
+  disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "6fe747418461d7b202824a3486ba8f4fa17a9bd0b1eddc743ba1d6d87f03391a";
+    sha256 = "7e9e0912c206c53cd6ee996265aa99d5c99c9334e37d025ce6114bc0416ffc14";
   };
 
   nativeBuildInputs = [
     setuptools-scm
   ];
+
   buildInputs = [
     pytest
   ];
 
   propagatedBuildInputs = [
-    six
-    numpy
+    packaging
   ];
 
   checkInputs = [
     pytestCheckHook
   ];
 
+  disabledTests = [
+    # ERROR: usage: __main__.py [options] [file_or_dir] [file_or_dir] [...]
+    # __main__.py: error: unrecognized arguments: --remote-data
+    "test_remote_data_url"
+    "test_remote_data_float_cmp"
+    "test_remote_data_ignore_whitespace"
+    "test_remote_data_ellipsis"
+    "test_remote_data_requires"
+    "test_remote_data_ignore_warnings"
+  ];
+
   meta = with lib; {
     description = "Pytest plugin with advanced doctest features";
     homepage = "https://astropy.org";
diff --git a/pkgs/development/python-modules/pytest-httpx/default.nix b/pkgs/development/python-modules/pytest-httpx/default.nix
index 6e7fd37b915e..b0bc07b6c162 100644
--- a/pkgs/development/python-modules/pytest-httpx/default.nix
+++ b/pkgs/development/python-modules/pytest-httpx/default.nix
@@ -9,13 +9,13 @@
 
 buildPythonPackage rec {
   pname = "pytest-httpx";
-  version = "0.12.1";
+  version = "0.13.0";
 
   src = fetchFromGitHub {
     owner = "Colin-b";
     repo = "pytest_httpx";
     rev = "v${version}";
-    sha256 = "sha256-eyR0h0fW5a+L6QslTnM0TPvQCto06aMcKCE+b8LqHcQ=";
+    sha256 = "0lh7df3ysxmjzvx6242xb6qiwpfxrnj70kjmw5sndvzmy5dfpxfc";
   };
 
   buildInputs = [ pytest ];
diff --git a/pkgs/development/python-modules/pytest-isort/default.nix b/pkgs/development/python-modules/pytest-isort/default.nix
index fe74f692df5e..e628e6a158c5 100644
--- a/pkgs/development/python-modules/pytest-isort/default.nix
+++ b/pkgs/development/python-modules/pytest-isort/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "pytest-isort";
-  version = "1.3.0";
+  version = "2.0.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "46a12331a701e2f21d48548b2828c8b0a7956dbf1cd5347163f537deb24332dd";
+    sha256 = "821a8c5c9c4f3a3c52cfa9c541fbe89ac9e28728125125af53724c4c3f129117";
   };
 
   propagatedBuildInputs = [ isort ];
diff --git a/pkgs/development/python-modules/pytest-relaxed/default.nix b/pkgs/development/python-modules/pytest-relaxed/default.nix
index 19d031b6a2b1..1030f76050ca 100644
--- a/pkgs/development/python-modules/pytest-relaxed/default.nix
+++ b/pkgs/development/python-modules/pytest-relaxed/default.nix
@@ -4,6 +4,7 @@
 , pytest
 , six
 , decorator
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
@@ -15,22 +16,23 @@ buildPythonPackage rec {
     sha256 = "e39a7e5b14e14dfff0de0ad720dfffa740c128d599ab14cfac13f4deb34164a6";
   };
 
+  # newer decorator versions are incompatible and cause the test suite to fail
+  # but only a few utility functions are used from this package which means it has no actual impact on test execution in paramiko and Fabric
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "decorator>=4,<5" "decorator>=4" \
+      --replace "pytest>=3,<5" "pytest>=3"
+  '';
+
   buildInputs = [ pytest ];
-  checkInputs = [ pytest ];
 
   propagatedBuildInputs = [ six decorator ];
 
-  patchPhase = ''
-    sed -i "s/pytest>=3,<5/pytest/g" setup.py
-  '';
+  checkInputs = [ pytestCheckHook ];
 
-  # skip tests due to dir requirements
+  # lots of assertion errors mainly around decorator
   doCheck = false;
 
-  checkPhase = ''
-    pytest tests
-  '';
-
   meta = with lib; {
     homepage = "https://pytest-relaxed.readthedocs.io/";
     description = "Relaxed test discovery/organization for pytest";
diff --git a/pkgs/development/python-modules/pytest-xprocess/default.nix b/pkgs/development/python-modules/pytest-xprocess/default.nix
index 0695b49191b4..fcd72ce9b976 100644
--- a/pkgs/development/python-modules/pytest-xprocess/default.nix
+++ b/pkgs/development/python-modules/pytest-xprocess/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "pytest-xprocess";
-  version = "0.17.1";
+  version = "0.18.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "59c739edee7f3f2258e7c77989241698e356c552f5efb28bb46b478616888bf6";
+    sha256 = "fd9f30ed1584b5833bc34494748adf0fb9de3ca7bacc4e88ad71989c21cba266";
   };
 
   nativeBuildInputs = [ setuptools-scm ];
diff --git a/pkgs/development/python-modules/pytest/4.nix b/pkgs/development/python-modules/pytest/4.nix
index c764b55d1f10..fd6d3507afb8 100644
--- a/pkgs/development/python-modules/pytest/4.nix
+++ b/pkgs/development/python-modules/pytest/4.nix
@@ -11,6 +11,11 @@ buildPythonPackage rec {
     sha256 = "50fa82392f2120cc3ec2ca0a75ee615be4c479e66669789771f1758332be4353";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "pluggy>=0.12,<1.0" "pluggy>=0.12,<2.0"
+  '';
+
   checkInputs = [ hypothesis mock ];
   buildInputs = [ setuptools-scm ];
   propagatedBuildInputs = [ attrs py setuptools six pluggy more-itertools atomicwrites wcwidth packaging ]
diff --git a/pkgs/development/python-modules/pytest/5.nix b/pkgs/development/python-modules/pytest/5.nix
index b3e69578d7eb..b38c1a759fe3 100644
--- a/pkgs/development/python-modules/pytest/5.nix
+++ b/pkgs/development/python-modules/pytest/5.nix
@@ -30,6 +30,11 @@ buildPythonPackage rec {
     sha256 = "1n67lk8iwlsmfdm8663k8l7isllg1xd3n9p1yla7885szhdk6ybr";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace "pluggy>=0.12,<1.0" "pluggy>=0.12,<2.0"
+  '';
+
   checkInputs = [ hypothesis pygments ];
   nativeBuildInputs = [ setuptools-scm ];
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/pytest/default.nix b/pkgs/development/python-modules/pytest/default.nix
index 19289426d71a..f2438622f6a6 100644
--- a/pkgs/development/python-modules/pytest/default.nix
+++ b/pkgs/development/python-modules/pytest/default.nix
@@ -19,14 +19,19 @@
 
 buildPythonPackage rec {
   pname = "pytest";
-  version = "6.2.4";
+  version = "6.2.5";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "50bcad0a0b9c5a72c8e4e7c9855a3ad496ca6a881a3641b4260605450772c54b";
+    sha256 = "131b36680866a76e6781d13f101efb86cf674ebb9762eb70d3082b6f29889e89";
   };
 
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "pluggy>=0.12,<1.0.0a1" "pluggy>=0.23,<2.0"
+  '';
+
   nativeBuildInputs = [ setuptools-scm ];
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/python-daemon/default.nix b/pkgs/development/python-modules/python-daemon/default.nix
index 246e253e191d..9df9bf8a593b 100644
--- a/pkgs/development/python-modules/python-daemon/default.nix
+++ b/pkgs/development/python-modules/python-daemon/default.nix
@@ -1,9 +1,12 @@
-{ lib, buildPythonPackage, fetchPypi
+{ lib
+, buildPythonPackage
+, fetchPypi
 , docutils
 , lockfile
 , mock
 , pytest_4
 , testscenarios
+, testtools
 , twine
 }:
 
@@ -16,13 +19,31 @@ buildPythonPackage rec {
     sha256 = "bda993f1623b1197699716d68d983bb580043cf2b8a66a01274d9b8297b0aeaf";
   };
 
-  nativeBuildInputs = [ twine ];
-  propagatedBuildInputs = [ docutils lockfile ];
+  nativeBuildInputs = [
+    twine
+  ];
 
-  checkInputs = [ pytest_4 mock testscenarios ];
+  propagatedBuildInputs = [
+    docutils
+    lockfile
+  ];
+
+  checkInputs = [
+    pytest_4
+    mock
+    testscenarios
+    testtools
+  ];
+
+  # tests disabled due to incompatibilities with testtools>=2.5.0
   checkPhase = ''
-    pytest -k 'not detaches_process_context \
-                and not standard_stream_file_descriptors'
+    runHook preCheck
+    pytest -k ' \
+      not detaches_process_context and \
+      not standard_stream_file_descriptors and \
+      not test_module_has_attribute and \
+      not test_module_attribute_has_duck_type'
+    runHook postCheck
   '';
 
   pythonImportsCheck = [
@@ -35,6 +56,10 @@ buildPythonPackage rec {
   meta = with lib; {
     description = "Library to implement a well-behaved Unix daemon process";
     homepage = "https://pagure.io/python-daemon/";
-    license = [ licenses.gpl3Plus licenses.asl20 ];
+    license = with licenses; [
+      gpl3Plus
+      asl20
+    ];
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/python-dotenv/default.nix b/pkgs/development/python-modules/python-dotenv/default.nix
index 6fbda114d338..22bf7ea7ece4 100644
--- a/pkgs/development/python-modules/python-dotenv/default.nix
+++ b/pkgs/development/python-modules/python-dotenv/default.nix
@@ -11,12 +11,12 @@
 
 buildPythonPackage rec {
   pname = "python-dotenv";
-  version = "0.17.1";
+  version = "0.19.0";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "b1ae5e9643d5ed987fc57cc2583021e38db531946518130777734f9589b3141f";
+    sha256 = "f521bc2ac9a8e03c736f62911605c5d83970021e3fa95b37d769e2bbbe9b6172";
   };
 
   propagatedBuildInputs = [ click ];
diff --git a/pkgs/development/python-modules/python-ethtool/default.nix b/pkgs/development/python-modules/python-ethtool/default.nix
index 03c147397068..e758f4a1ef71 100644
--- a/pkgs/development/python-modules/python-ethtool/default.nix
+++ b/pkgs/development/python-modules/python-ethtool/default.nix
@@ -8,13 +8,13 @@
 
 buildPythonPackage rec {
   pname = "python-ethtool";
-  version = "0.14";
+  version = "0.15";
 
   src = fetchFromGitHub {
     owner = "fedora-python";
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-Sp7ssfLZ/1FEKrvX257pKcaureZ5mdpJ7jCEh/ft1l0=";
+    sha256 = "0arkcfq64a4fl88vjjsx4gd3mhcpa7mpq6sblpkgs4k4m9mccz6i";
   };
 
   postPatch = ''
diff --git a/pkgs/development/python-modules/python-gitlab/default.nix b/pkgs/development/python-modules/python-gitlab/default.nix
index 831ae6e39668..a5c40533c169 100644
--- a/pkgs/development/python-modules/python-gitlab/default.nix
+++ b/pkgs/development/python-modules/python-gitlab/default.nix
@@ -10,12 +10,12 @@
 
 buildPythonPackage rec {
   pname = "python-gitlab";
-  version = "2.10.0";
+  version = "2.10.1";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-N2s+mCOBzsc0RxxQKz2ixueFio300DyZNJnmp1k5UOY=";
+    sha256 = "7afa7d7c062fa62c173190452265a30feefb844428efc58ea5244f3b9fc0d40f";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/python-lsp-server/default.nix b/pkgs/development/python-modules/python-lsp-server/default.nix
index 5d13a50a11fd..60215fa0b4cd 100644
--- a/pkgs/development/python-modules/python-lsp-server/default.nix
+++ b/pkgs/development/python-modules/python-lsp-server/default.nix
@@ -45,6 +45,12 @@ buildPythonPackage rec {
     sha256 = "sha256-TyXKlXeXMyq+bQq9ngDm0SuW+rAhDlOVlC3mDI1THwk=";
   };
 
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "--cov-report html --cov-report term --junitxml=pytest.xml" "" \
+      --replace "--cov pylsp --cov test" ""
+  '';
+
   propagatedBuildInputs = [
     jedi
     pluggy
@@ -52,14 +58,14 @@ buildPythonPackage rec {
     setuptools
     ujson
   ] ++ lib.optional withAutopep8 autopep8
-    ++ lib.optional withFlake8 flake8
-    ++ lib.optional withMccabe mccabe
-    ++ lib.optional withPycodestyle pycodestyle
-    ++ lib.optional withPydocstyle pydocstyle
-    ++ lib.optional withPyflakes pyflakes
-    ++ lib.optional withPylint pylint
-    ++ lib.optional withRope rope
-    ++ lib.optional withYapf yapf;
+  ++ lib.optional withFlake8 flake8
+  ++ lib.optional withMccabe mccabe
+  ++ lib.optional withPycodestyle pycodestyle
+  ++ lib.optional withPydocstyle pydocstyle
+  ++ lib.optional withPyflakes pyflakes
+  ++ lib.optional withPylint pylint
+  ++ lib.optional withRope rope
+  ++ lib.optional withYapf yapf;
 
   checkInputs = [
     flaky
@@ -70,7 +76,10 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  disabledTests = lib.optional (!withPycodestyle) "test_workspace_loads_pycodestyle_config";
+  disabledTests = [
+    # pytlint output changed
+    "test_lint_free_pylint"
+  ] ++ lib.optional (!withPycodestyle) "test_workspace_loads_pycodestyle_config";
 
   disabledTestPaths = lib.optional (!withAutopep8) "test/plugins/test_autopep8_format.py"
     ++ lib.optional (!withRope) "test/plugins/test_completion.py"
@@ -83,12 +92,6 @@ buildPythonPackage rec {
     ++ lib.optional (!withRope) "test/plugins/test_rope_rename.py"
     ++ lib.optional (!withYapf) "test/plugins/test_yapf_format.py";
 
-  postPatch = ''
-    substituteInPlace setup.cfg \
-      --replace "--cov-report html --cov-report term --junitxml=pytest.xml" "" \
-      --replace "--cov pylsp --cov test" ""
-  '';
-
   preCheck = ''
     export HOME=$(mktemp -d);
   '';
diff --git a/pkgs/development/python-modules/python-rapidjson/default.nix b/pkgs/development/python-modules/python-rapidjson/default.nix
index 63dc4018b27d..a939caf49703 100644
--- a/pkgs/development/python-modules/python-rapidjson/default.nix
+++ b/pkgs/development/python-modules/python-rapidjson/default.nix
@@ -8,13 +8,13 @@
 }:
 
 buildPythonPackage rec {
-  version = "1.0";
+  version = "1.4";
   pname = "python-rapidjson";
   disabled = pythonOlder "3.4";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a61fa61e41b0b85ba9e78444242fddcb3be724de1df79314e6b4766b66e4e11c";
+    sha256 = "018c20d3983cccfdc9cfed64407d4ba861ef3d64fe324a486f7130431afdefa7";
   };
 
   LC_ALL="en_US.utf-8";
diff --git a/pkgs/development/python-modules/pytube/default.nix b/pkgs/development/python-modules/pytube/default.nix
index 93ff39360830..bd5b9e374f16 100644
--- a/pkgs/development/python-modules/pytube/default.nix
+++ b/pkgs/development/python-modules/pytube/default.nix
@@ -7,7 +7,7 @@
 
 buildPythonPackage rec {
   pname = "pytube";
-  version = "10.9.3";
+  version = "11.0.1";
 
   disabled = pythonOlder "3.6";
 
@@ -15,7 +15,7 @@ buildPythonPackage rec {
     owner = "pytube";
     repo = "pytube";
     rev = "v${version}";
-    sha256 = "sha256-x4u68O9dNhDZ+1Q+S4ou6zPqoR2/Yn5lcKgR2kyM/uo=";
+    sha256 = "04s4hganb6x0dlfyyg9gjah5z0vxd7bxzqwgvd28hqnf0iwc2byb";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/pyusb/default.nix b/pkgs/development/python-modules/pyusb/default.nix
index 43ae18741e1d..05fb6b682716 100644
--- a/pkgs/development/python-modules/pyusb/default.nix
+++ b/pkgs/development/python-modules/pyusb/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "pyusb";
-  version = "1.1.1";
+  version = "1.2.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "7d449ad916ce58aff60b89aae0b65ac130f289c24d6a5b7b317742eccffafc38";
+    sha256 = "a4cc7404a203144754164b8b40994e2849fde1cfff06b08492f12fff9d9de7b9";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/pyvips/default.nix b/pkgs/development/python-modules/pyvips/default.nix
index ea40fc573b63..c3eb750783fd 100644
--- a/pkgs/development/python-modules/pyvips/default.nix
+++ b/pkgs/development/python-modules/pyvips/default.nix
@@ -3,11 +3,11 @@
 
 buildPythonPackage rec {
   pname = "pyvips";
-  version = "2.1.14";
+  version = "2.1.15";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "244e79c625be65237677c79424d4476de6c406805910015d4adbd0186c64a6a2";
+    sha256 = "8bca4077dbdc1434dcbc6759407367b6561e3505aa9555b1bc0b45989dcf50b2";
   };
 
   nativeBuildInputs = [ pytest-runner pkgconfig pkg-config ];
diff --git a/pkgs/development/python-modules/pyzmq/default.nix b/pkgs/development/python-modules/pyzmq/default.nix
index 5aca8d6d66c6..816c46204f88 100644
--- a/pkgs/development/python-modules/pyzmq/default.nix
+++ b/pkgs/development/python-modules/pyzmq/default.nix
@@ -9,11 +9,11 @@
 
 buildPythonPackage rec {
   pname = "pyzmq";
-  version = "22.1.0";
+  version = "22.2.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "7040d6dd85ea65703904d023d7f57fab793d7ffee9ba9e14f3b897f34ff2415d";
+    sha256 = "6d18c76676771fd891ca8e0e68da0bbfb88e30129835c0ade748016adb3b6242";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/qtpy/default.nix b/pkgs/development/python-modules/qtpy/default.nix
index 17e1d9dbe83b..7ee51449ed90 100644
--- a/pkgs/development/python-modules/qtpy/default.nix
+++ b/pkgs/development/python-modules/qtpy/default.nix
@@ -2,11 +2,11 @@
 
 buildPythonPackage rec {
   pname = "QtPy";
-  version = "1.9.0";
+  version = "1.10.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "13cw8l7zrhbdi03k1wl1pg9xdl4ahdfa7yz8gd0f23sxnm22rdrd";
+    sha256 = "3d20f010caa3b2c04835d6a2f66f8873b041bdaf7a76085c2a0d7890cdd65ea9";
   };
 
   # no concrete propagatedBuildInputs as multiple backends are supposed
diff --git a/pkgs/development/python-modules/quantities/default.nix b/pkgs/development/python-modules/quantities/default.nix
index 233eb8a44b32..28e08eade43d 100644
--- a/pkgs/development/python-modules/quantities/default.nix
+++ b/pkgs/development/python-modules/quantities/default.nix
@@ -2,7 +2,7 @@
 , buildPythonPackage
 , fetchPypi
 , numpy
-, python
+, pytestCheckHook
 }:
 
 buildPythonPackage rec {
@@ -14,15 +14,27 @@ buildPythonPackage rec {
     sha256 = "67546963cb2a519b1a4aa43d132ef754360268e5d551b43dd1716903d99812f0";
   };
 
-  propagatedBuildInputs = [ numpy ];
+  propagatedBuildInputs = [
+    numpy
+  ];
 
-  checkPhase = ''
-    ${python.interpreter} setup.py test -V 1
-  '';
+  checkInputs = [
+    pytestCheckHook
+  ];
 
-  meta = {
-    description = "Quantities is designed to handle arithmetic and";
+  disabledTests = [
+    # Tests don't work with current numpy
+    # https://github.com/python-quantities/python-quantities/pull/195
+    "test_arctan2"
+    "test_fix"
+  ];
+
+  pythonImportsCheck = [ "quantities" ];
+
+  meta = with lib; {
+    description = "Quantities is designed to handle arithmetic and conversions of physical quantities";
     homepage = "https://python-quantities.readthedocs.io/";
-    license = lib.licenses.bsd2;
+    license = licenses.bsd2;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/queuelib/default.nix b/pkgs/development/python-modules/queuelib/default.nix
index 7534974237a9..cd83914669e5 100644
--- a/pkgs/development/python-modules/queuelib/default.nix
+++ b/pkgs/development/python-modules/queuelib/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "queuelib";
-  version = "1.6.1";
+  version = "1.6.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "631d067c9be57e395c382d680d3653ca1452cd29e8da25c5e8d94b5c0c528c31";
+    sha256 = "4b207267f2642a8699a1f806045c56eb7ad1a85a10c0e249884580d139c2fcd2";
   };
 
   buildInputs = [ pytest ];
diff --git a/pkgs/development/python-modules/r2pipe/default.nix b/pkgs/development/python-modules/r2pipe/default.nix
index 3fbb0fb4042c..ffe784ad1995 100644
--- a/pkgs/development/python-modules/r2pipe/default.nix
+++ b/pkgs/development/python-modules/r2pipe/default.nix
@@ -9,7 +9,7 @@
 
 buildPythonPackage rec {
   pname = "r2pipe";
-  version = "1.5.3";
+  version = "1.6.0";
 
   postPatch = let
     r2lib = "${lib.getOutput "lib" radare2}/lib";
@@ -27,7 +27,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8f3708195c8a6e91c5753940fd348cd821df1389d23b889b01b3e88acf407485";
+    sha256 = "f7d1f629130fac597dc444df57168cf011a18abb1be2f690c8993fc5fb4c78a0";
   };
 
   # Tiny sanity check to make sure r2pipe finds radare2 (since r2pipe doesn't
diff --git a/pkgs/development/python-modules/rdflib-jsonld/default.nix b/pkgs/development/python-modules/rdflib-jsonld/default.nix
index 6e038dd33433..9a0b02c329f7 100644
--- a/pkgs/development/python-modules/rdflib-jsonld/default.nix
+++ b/pkgs/development/python-modules/rdflib-jsonld/default.nix
@@ -17,5 +17,7 @@ buildPythonPackage rec {
     license = licenses.bsdOriginal;
     description = "rdflib extension adding JSON-LD parser and serializer";
     maintainers = [ maintainers.koslambrou ];
+    # incomptiable with rdflib 6.0.0, half of the test suite fails with import and atrribute errors
+    broken = true;
   };
 }
diff --git a/pkgs/development/python-modules/rdflib/default.nix b/pkgs/development/python-modules/rdflib/default.nix
index 261ba794e70a..5b16e2f744e2 100644
--- a/pkgs/development/python-modules/rdflib/default.nix
+++ b/pkgs/development/python-modules/rdflib/default.nix
@@ -10,11 +10,11 @@
 
 buildPythonPackage rec {
   pname = "rdflib";
-  version = "5.0.0";
+  version = "6.0.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0mdi7xh4zcr3ngqwlgqdqf0i5bxghwfddyxdng1zwpiqkpa9s53q";
+    sha256 = "7ce4d757eb26f4dd43205ec340d8c097f29e5adfe45d6ea20238c731dc679879";
   };
 
   propagatedBuildInputs = [isodate html5lib SPARQLWrapper ];
diff --git a/pkgs/development/python-modules/regex/default.nix b/pkgs/development/python-modules/regex/default.nix
index 0445b02c1f33..92ce64d186db 100644
--- a/pkgs/development/python-modules/regex/default.nix
+++ b/pkgs/development/python-modules/regex/default.nix
@@ -7,11 +7,11 @@
 
 buildPythonPackage rec {
   pname = "regex";
-  version = "2021.4.4";
+  version = "2021.8.28";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-Uro9P5uULEnX5LwQW7KFUcRAZfE5plBiq3kSvvEMmvs=";
+    sha256 = "f585cbbeecb35f35609edccb95efd95a3e35824cd7752b586503f7e6087303f1";
   };
 
   # Sources for different Python releases are located in same folder
diff --git a/pkgs/development/python-modules/reportlab/default.nix b/pkgs/development/python-modules/reportlab/default.nix
index c9f2600efe1e..71d4cd7425d1 100644
--- a/pkgs/development/python-modules/reportlab/default.nix
+++ b/pkgs/development/python-modules/reportlab/default.nix
@@ -11,11 +11,11 @@ let
   ft = freetype.overrideAttrs (oldArgs: { dontDisableStatic = true; });
 in buildPythonPackage rec {
   pname = "reportlab";
-  version = "3.5.67";
+  version = "3.6.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0cf2206c73fbca752c8bd39e12bb9ad7f2d01e6fcb2b25b9eaf94ea042fe86c9";
+    sha256 = "68f9324000cfc5570b5a59a92306691b5d655078a399f20bc72c2581fe903261";
   };
 
   checkInputs = [ glibcLocales ];
diff --git a/pkgs/development/python-modules/requests/default.nix b/pkgs/development/python-modules/requests/default.nix
index 8b5514f63936..4dfd4fd623d4 100644
--- a/pkgs/development/python-modules/requests/default.nix
+++ b/pkgs/development/python-modules/requests/default.nix
@@ -1,4 +1,6 @@
 { lib
+, brotli
+, brotlicffi
 , buildPythonPackage
 , certifi
 , chardet
@@ -9,6 +11,8 @@
 , pytestCheckHook
 , urllib3
 , isPy27
+, isPy3k
+, trustme
 }:
 
 buildPythonPackage rec {
@@ -32,6 +36,11 @@ buildPythonPackage rec {
     chardet
     idna
     urllib3
+  ] ++ lib.optionals (isPy3k) [
+    brotlicffi
+    charset-normalizer
+  ] ++ lib.optionals (isPy27) [
+    brotli
   ];
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/rich/default.nix b/pkgs/development/python-modules/rich/default.nix
index 323bd8ba8685..6c953a4579ea 100644
--- a/pkgs/development/python-modules/rich/default.nix
+++ b/pkgs/development/python-modules/rich/default.nix
@@ -13,7 +13,7 @@
 
 buildPythonPackage rec {
   pname = "rich";
-  version = "10.7.0";
+  version = "10.9.0";
   format = "pyproject";
   disabled = pythonOlder "3.6";
 
@@ -21,7 +21,7 @@ buildPythonPackage rec {
     owner = "willmcgugan";
     repo = pname;
     rev = "v${version}";
-    sha256 = "1drh08cmcn8dqi0mpfwscz3ljsv2s60kyhxy6iiw5si7rf717j4p";
+    sha256 = "0lf2s7n9b31aavwl5xjl3x1pjc756s8pbk0whh5kag80z5v6qc32";
   };
 
   nativeBuildInputs = [ poetry-core ];
diff --git a/pkgs/development/python-modules/robotframework-sshlibrary/default.nix b/pkgs/development/python-modules/robotframework-sshlibrary/default.nix
index 4d72a2b3b0a1..82a5fd3fed67 100644
--- a/pkgs/development/python-modules/robotframework-sshlibrary/default.nix
+++ b/pkgs/development/python-modules/robotframework-sshlibrary/default.nix
@@ -7,12 +7,12 @@
 }:
 
 buildPythonPackage rec {
-  version = "3.6.0";
+  version = "3.7.0";
   pname = "robotframework-sshlibrary";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "169c343f4db71e1969169fa6f383ca7fff549aa8f83bdd3d9cbd03cea928b688";
+    sha256 = "55bd5a11bb1fe60a5a83446e6a3e1e81b13fc671e3b660aa55912a263c1f63aa";
   };
 
   # unit tests are impure
diff --git a/pkgs/development/python-modules/ruamel_yaml/default.nix b/pkgs/development/python-modules/ruamel_yaml/default.nix
index 863b62c1bcce..efd418e454d4 100644
--- a/pkgs/development/python-modules/ruamel_yaml/default.nix
+++ b/pkgs/development/python-modules/ruamel_yaml/default.nix
@@ -10,11 +10,11 @@
 
 buildPythonPackage rec {
   pname = "ruamel.yaml";
-  version = "0.17.9";
+  version = "0.17.16";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "374373b4743aee9f6d9f40bea600fe020a7ac7ae36b838b4a6a93f72b584a14c";
+    sha256 = "1a771fc92d3823682b7f0893ad56cb5a5c87c48e62b5399d6f42c8759a583b33";
   };
 
   # Tests use relative paths
diff --git a/pkgs/development/python-modules/sagemaker/default.nix b/pkgs/development/python-modules/sagemaker/default.nix
index 2b16b99bea73..23fa728a78a0 100644
--- a/pkgs/development/python-modules/sagemaker/default.nix
+++ b/pkgs/development/python-modules/sagemaker/default.nix
@@ -16,11 +16,11 @@
 
 buildPythonPackage rec {
   pname = "sagemaker";
-  version = "2.54.0";
+  version = "2.57.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-uLsBHqzpcuTugRXBihdbib64l396m+os39OhP+tLLCM=";
+    sha256 = "b03b340fe54f91b0533d3ce19d5b7fdf403da21b5befab70a9915466e48f6e75";
   };
 
   pythonImportsCheck = [
diff --git a/pkgs/development/python-modules/sanic-testing/default.nix b/pkgs/development/python-modules/sanic-testing/default.nix
index b59781e5c459..5e7deb51362e 100644
--- a/pkgs/development/python-modules/sanic-testing/default.nix
+++ b/pkgs/development/python-modules/sanic-testing/default.nix
@@ -19,6 +19,13 @@ buildPythonPackage rec {
     sha256 = "1pf619cd3dckn3d8gh18vbn7dflvb0mzpf6frx4y950x2j3rdplk";
   };
 
+  postPatch = ''
+    # https://github.com/sanic-org/sanic-testing/issues/19
+    substituteInPlace setup.py \
+      --replace '"websockets==8.1",' '"websockets>=9.1",' \
+      --replace "httpx==0.18.*" "httpx"
+  '';
+
   propagatedBuildInputs = [
     httpx
     sanic
@@ -30,12 +37,6 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
-  postPatch = ''
-    # https://github.com/sanic-org/sanic-testing/issues/19
-    substituteInPlace setup.py \
-      --replace '"websockets==8.1",' '"websockets>=9.1",'
-  '';
-
   # `sanic` is explicitly set to null when building `sanic` itself
   # to prevent infinite recursion.  In that case we skip running
   # the package at all.
diff --git a/pkgs/development/python-modules/scancode-toolkit/default.nix b/pkgs/development/python-modules/scancode-toolkit/default.nix
index fa7dabc27293..177032aea7f3 100644
--- a/pkgs/development/python-modules/scancode-toolkit/default.nix
+++ b/pkgs/development/python-modules/scancode-toolkit/default.nix
@@ -37,12 +37,12 @@
 }:
 buildPythonPackage rec {
   pname = "scancode-toolkit";
-  version = "21.6.7";
+  version = "21.8.4";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "056923ce556cd6d402e5cc98567cb0331a1b6349d03ec565f8ce1c9c37f3a783";
+    sha256 = "c18340067244274c67e166f701c60e747e1d0bccb17efc99f277a4bc0a5a13c6";
   };
 
   dontConfigure = true;
diff --git a/pkgs/development/python-modules/schema-salad/default.nix b/pkgs/development/python-modules/schema-salad/default.nix
index 007cca251436..e6342b90bba4 100644
--- a/pkgs/development/python-modules/schema-salad/default.nix
+++ b/pkgs/development/python-modules/schema-salad/default.nix
@@ -12,11 +12,11 @@
 
 buildPythonPackage rec {
   pname = "schema-salad";
-  version = "8.1.20210716111910";
+  version = "8.1.20210721123742";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3f851b385d044c58d359285ba471298b6199478a4978f892a83b15cbfb282f25";
+    sha256 = "1549555b9b5656cfc690716f04fb76b9fa002feb278638c446522f030632b450";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/scikit-image/default.nix b/pkgs/development/python-modules/scikit-image/default.nix
index f7d3fd63b17b..b34d3ff7b8de 100644
--- a/pkgs/development/python-modules/scikit-image/default.nix
+++ b/pkgs/development/python-modules/scikit-image/default.nix
@@ -18,11 +18,11 @@
 
 buildPythonPackage rec {
   pname = "scikit-image";
-  version = "0.18.1";
+  version = "0.18.3";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fbb618ca911867bce45574c1639618cdfb5d94e207432b19bc19563d80d2f171";
+    sha256 = "ecae99f93f4c5e9b1bf34959f4dc596c41f2f6b2fc407d9d9ddf85aebd3137ca";
   };
 
   nativeBuildInputs = [ cython ];
diff --git a/pkgs/development/python-modules/scipy/default.nix b/pkgs/development/python-modules/scipy/default.nix
index 7a9643aa7d24..2e19d2d42042 100644
--- a/pkgs/development/python-modules/scipy/default.nix
+++ b/pkgs/development/python-modules/scipy/default.nix
@@ -3,7 +3,9 @@
 , fetchPypi
 , python
 , buildPythonPackage
+, cython
 , gfortran
+, pythran
 , nose
 , pytest
 , pytest-xdist
@@ -13,18 +15,21 @@
 
 buildPythonPackage rec {
   pname = "scipy";
-  version = "1.6.3";
+  version = "1.7.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a75b014d3294fce26852a9d04ea27b5671d86736beb34acdfc05859246260707";
+    sha256 = "6b47d5fa7ea651054362561a28b1ccc8da9368a39514c1bbf6c0977a1c376764";
   };
 
-  checkInputs = [ nose pytest pytest-xdist ];
-  nativeBuildInputs = [ gfortran ];
+  nativeBuildInputs = [ cython gfortran pythran ];
+
   buildInputs = [ numpy.blas pybind11 ];
+
   propagatedBuildInputs = [ numpy ];
 
+  checkInputs = [ nose pytest pytest-xdist ];
+
   # Remove tests because of broken wrapper
   prePatch = ''
     rm scipy/linalg/tests/test_lapack.py
@@ -41,7 +46,6 @@ buildPythonPackage rec {
     ln -s ${numpy.cfg} site.cfg
   '';
 
-
   # disable stackprotector on aarch64-darwin for now
   #
   # build error:
diff --git a/pkgs/development/python-modules/screeninfo/default.nix b/pkgs/development/python-modules/screeninfo/default.nix
index 80933043b3b9..21b3f30e1323 100644
--- a/pkgs/development/python-modules/screeninfo/default.nix
+++ b/pkgs/development/python-modules/screeninfo/default.nix
@@ -1,36 +1,50 @@
-{ lib, buildPythonApplication, fetchPypi, isPy27, isPy36, dataclasses, libX11, libXinerama, libXrandr }:
+{ lib
+, buildPythonApplication
+, dataclasses
+, fetchPypi
+, libX11
+, libXinerama
+, libXrandr
+, pytestCheckHook
+, pythonOlder
+}:
 
 buildPythonApplication rec {
   pname = "screeninfo";
-  version = "0.6.7";
-  disabled = isPy27; # dataclasses isn't available for python2
+  version = "0.7";
+
+  disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "1c4bac1ca329da3f68cbc4d2fbc92256aa9bb8ff8583ee3e14f91f0a7baa69cb";
+    sha256 = "12a97c3527e3544ac5dbd7c1204283e2653d655cbd15844c990a83b1b13ef500";
   };
 
-  # dataclasses is a compatibility shim for python 3.6 ONLY
-  patchPhase = if isPy36 then "" else ''
-    substituteInPlace setup.py \
-      --replace "\"dataclasses\"," ""
-  '' + ''
-    substituteInPlace screeninfo/enumerators/xinerama.py \
-      --replace "load_library(\"X11\")" "ctypes.cdll.LoadLibrary(\"${libX11}/lib/libX11.so\")" \
-      --replace "load_library(\"Xinerama\")" "ctypes.cdll.LoadLibrary(\"${libXinerama}/lib/libXinerama.so\")"
-    substituteInPlace screeninfo/enumerators/xrandr.py \
-      --replace "load_library(\"X11\")" "ctypes.cdll.LoadLibrary(\"${libX11}/lib/libX11.so\")" \
-      --replace "load_library(\"Xrandr\")" "ctypes.cdll.LoadLibrary(\"${libXrandr}/lib/libXrandr.so\")"
-  '';
+  propagatedBuildInputs = lib.optionals (pythonOlder "3.7") [
+    dataclasses
+  ];
 
-  propagatedBuildInputs = lib.optional isPy36 dataclasses;
+  buildInputs = [
+    libX11
+    libXinerama
+    libXrandr
+  ];
 
-  buildInputs = [ libX11 libXinerama libXrandr];
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  disabledTestPaths = [
+    # We don't have a screen
+    "screeninfo/test_screeninfo.py"
+  ];
+
+  pythonImportsCheck = [ "screeninfo" ];
 
   meta = with lib; {
     description = "Fetch location and size of physical screens";
     homepage = "https://github.com/rr-/screeninfo";
     license = licenses.mit;
-    maintainers = [ maintainers.nickhu ];
+    maintainers = with maintainers; [ nickhu ];
   };
 }
diff --git a/pkgs/development/python-modules/setuptools-scm/default.nix b/pkgs/development/python-modules/setuptools-scm/default.nix
index a4cff6d056b0..87f8c3d13ae4 100644
--- a/pkgs/development/python-modules/setuptools-scm/default.nix
+++ b/pkgs/development/python-modules/setuptools-scm/default.nix
@@ -1,15 +1,25 @@
-{ lib, buildPythonPackage, fetchPypi, toml }:
+{ lib, buildPythonPackage, fetchPypi, toml, tomli }:
 
 buildPythonPackage rec {
-  pname = "setuptools_scm";
+  pname = "setuptools-scm";
+  # don't update to 6.1.0 or 6.2.0, releases were pulled because of regression
+  # https://github.com/pypa/setuptools_scm/issues/615
   version = "6.0.1";
 
   src = fetchPypi {
-    inherit pname version;
-    sha256 = "d1925a69cb07e9b29416a275b9fadb009a23c148ace905b2fb220649a6c18e92";
+    pname = "setuptools_scm";
+    inherit version;
+    sha256 = "sha256-0ZJaacsH6bKUFqJ1ufrbAJojwUis6QWy+yIGSabBjpI=";
   };
 
-  propagatedBuildInputs = [ toml ];
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "tomli~=1.0.0" "tomli>=1.0.0"
+  '';
+
+  # TODO: figure out why both toml and tomli are needed when only tomli is listed in setuptools-scm
+  # if not both are listed some packages like zipp silently fallback to a 0.0.0 version number and break version pins in other packages
+  propagatedBuildInputs = [ toml tomli ];
 
   # Requires pytest, circular dependency
   doCheck = false;
diff --git a/pkgs/development/python-modules/simple-salesforce/default.nix b/pkgs/development/python-modules/simple-salesforce/default.nix
index 592e23578095..7a0cebc44f92 100644
--- a/pkgs/development/python-modules/simple-salesforce/default.nix
+++ b/pkgs/development/python-modules/simple-salesforce/default.nix
@@ -12,13 +12,13 @@
 
 buildPythonPackage rec {
   pname = "simple-salesforce";
-  version = "1.11.2";
+  version = "1.11.3";
 
   src = fetchFromGitHub {
     owner = pname;
     repo = pname;
     rev = "v${version}";
-    sha256 = "1xysym0b1qnxck4hbj5d0l5wapwfahmkr280f6iskz2hi5j2j1yb";
+    sha256 = "16bd40n0xy0vmsgi2499vc6mx57ksyjrm6v88bwxp49p9qrm4a23";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/simplejson/default.nix b/pkgs/development/python-modules/simplejson/default.nix
index 0d4d45cce5d6..52e55c71aff0 100644
--- a/pkgs/development/python-modules/simplejson/default.nix
+++ b/pkgs/development/python-modules/simplejson/default.nix
@@ -7,13 +7,13 @@
 
 buildPythonPackage rec {
   pname = "simplejson";
-  version = "3.17.3";
+  version = "3.17.5";
 
   src = fetchFromGitHub {
     owner = pname;
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-Ev1vKyxexPvTT+esf9ngUcHu70Brl27P3qbS5fK2HxU=";
+    sha256 = "1vljsd5bk12gasadkxcddwhmp38fj64x1aqi4frk3frq9lp8h3a1";
   };
 
   checkInputs = [
diff --git a/pkgs/development/python-modules/singledispatch/default.nix b/pkgs/development/python-modules/singledispatch/default.nix
index 8fa62e835f22..837271b4d57c 100644
--- a/pkgs/development/python-modules/singledispatch/default.nix
+++ b/pkgs/development/python-modules/singledispatch/default.nix
@@ -8,11 +8,11 @@
 
 buildPythonPackage rec {
   pname = "singledispatch";
-  version = "3.6.2";
+  version = "3.7.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "d5bb9405a4b8de48e36709238e8b91b4f6f300f81a5132ba2531a9a738eca391";
+    sha256 = "c1a4d5c1da310c3fd8fccfb8d4e1cb7df076148fd5d858a819e37fffe44f3092";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/slack-sdk/default.nix b/pkgs/development/python-modules/slack-sdk/default.nix
index 6183ee7b0cba..92712b2ce41f 100644
--- a/pkgs/development/python-modules/slack-sdk/default.nix
+++ b/pkgs/development/python-modules/slack-sdk/default.nix
@@ -20,14 +20,14 @@
 
 buildPythonPackage rec {
   pname = "slack-sdk";
-  version = "3.10.0";
+  version = "3.10.1";
   disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "slackapi";
     repo = "python-slack-sdk";
     rev = "v${version}";
-    sha256 = "sha256-FOpUO9bXrEOgYGmRmAhHnovzBafu6D2ZSLcgw0+0uzs=";
+    sha256 = "1m9jbn5wn892f22lxkxgahlbnwflak50hfjrydblp4agsag94nsg";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/slowapi/default.nix b/pkgs/development/python-modules/slowapi/default.nix
index 921a191d5fa1..a1e54a6c5f93 100644
--- a/pkgs/development/python-modules/slowapi/default.nix
+++ b/pkgs/development/python-modules/slowapi/default.nix
@@ -43,6 +43,12 @@ buildPythonPackage rec {
     starlette
   ];
 
+  disabledTests = [
+    # E       AssertionError: Regex pattern 'parameter `request` must be an instance of starlette.requests.Request' does not match 'This portal is not running'.
+    "test_endpoint_request_param_invalid"
+    "test_endpoint_response_param_invalid"
+  ];
+
   patches = [
     # Switch to poetry-core, https://github.com/laurentS/slowapi/pull/54
     (fetchpatch {
diff --git a/pkgs/development/python-modules/smart-meter-texas/default.nix b/pkgs/development/python-modules/smart-meter-texas/default.nix
index f8bd6825673c..a9364ad0d1f2 100644
--- a/pkgs/development/python-modules/smart-meter-texas/default.nix
+++ b/pkgs/development/python-modules/smart-meter-texas/default.nix
@@ -3,13 +3,14 @@
 , pythonOlder
 , fetchFromGitHub
 , aiohttp
+, asn1
 , python-dateutil
 , tenacity
 }:
 
 buildPythonPackage rec {
   pname = "smart-meter-texas";
-  version = "0.4.4";
+  version = "0.4.7";
 
   disabled = pythonOlder "3.6";
 
@@ -17,7 +18,7 @@ buildPythonPackage rec {
     owner = "grahamwetzler";
     repo = "smart-meter-texas";
     rev = "v${version}";
-    sha256 = "sha256-jewibcsqWnl0OQ2oEEOSOcyyDCIGZiG4EZQfuFUbxK4=";
+    sha256 = "1hfvv3kpkc7i9mn58bjgvwjj0mi2syr8fv4r8bwbhq5sailma27j";
   };
 
   postPatch = ''
@@ -27,6 +28,7 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [
     aiohttp
+    asn1
     python-dateutil
     tenacity
   ];
diff --git a/pkgs/development/python-modules/smart-open/default.nix b/pkgs/development/python-modules/smart-open/default.nix
index 5e86281642af..bbe8b1b468ee 100644
--- a/pkgs/development/python-modules/smart-open/default.nix
+++ b/pkgs/development/python-modules/smart-open/default.nix
@@ -15,7 +15,7 @@
 
 buildPythonPackage rec {
   pname = "smart-open";
-  version = "5.2.0";
+  version = "5.2.1";
 
   disabled = pythonOlder "3.5";
 
@@ -23,7 +23,7 @@ buildPythonPackage rec {
     owner = "RaRe-Technologies";
     repo = "smart_open";
     rev = "v${version}";
-    sha256 = "sha256-eC9BYHeACzGp382QBNgLcNMYDkHi0WXyEj/Re9ShXuA=";
+    sha256 = "13a1qsb4vwrhx45hz4qcl0d7bgv20ai5vsy7cq0q6qbj212nff19";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/snowflake-connector-python/default.nix b/pkgs/development/python-modules/snowflake-connector-python/default.nix
index 0b0c961e7d09..81d939db66be 100644
--- a/pkgs/development/python-modules/snowflake-connector-python/default.nix
+++ b/pkgs/development/python-modules/snowflake-connector-python/default.nix
@@ -24,12 +24,12 @@
 
 buildPythonPackage rec {
   pname = "snowflake-connector-python";
-  version = "2.5.1";
+  version = "2.6.0";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8af2a51ac890d9e0ffe0cd509ba83198076e2564fb8fdc63c6814b773e70b33a";
+    sha256 = "0198d9c1934540ae9c7276d98f1048f3432160613d9d0e49398112bb21b0f0bb";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/snscrape/default.nix b/pkgs/development/python-modules/snscrape/default.nix
index a8f565aa3533..98933759f0bb 100644
--- a/pkgs/development/python-modules/snscrape/default.nix
+++ b/pkgs/development/python-modules/snscrape/default.nix
@@ -1,33 +1,48 @@
 { lib
-, buildPythonPackage
-, isPy3k
-, fetchPypi
-, setuptools-scm
-, setuptools
-, requests
-, lxml
 , beautifulsoup4
+, buildPythonPackage
+, fetchFromGitHub
+, lxml
+, pythonOlder
+, pytz
+, requests
+, setuptools-scm
 }:
 
 buildPythonPackage rec {
   pname = "snscrape";
-  version = "0.3.4";
+  version = "unstable-2021-08-30";
 
-  disabled = !isPy3k;
+  disabled = pythonOlder "3.8";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "36ba7f95c8bf5202749189f760e591952f19c849379c35ff598aafafe5d0cfef";
+  src = fetchFromGitHub {
+    owner = "JustAnotherArchivist";
+    repo = pname;
+    rev = "c76f1637ce1d7a154af83495b67ead2559cd5715";
+    sha256 = "01x4961fxj1p98y6fcyxw5sv8fa87x41fdx9p31is12bdkmqxi6v";
   };
 
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
+
+  nativeBuildInputs = [
+    setuptools-scm
+  ];
+
+  propagatedBuildInputs = [
+    beautifulsoup4
+    lxml
+    requests
+  ] ++ lib.optionals (pythonOlder "3.9") [
+    pytz
+  ];
+
   # There are no tests; make sure the executable works.
   checkPhase = ''
     export PATH=$PATH:$out/bin
     snscrape --help
   '';
 
-  nativeBuildInputs = [ setuptools-scm ];
-  propagatedBuildInputs = [ setuptools requests lxml beautifulsoup4 ];
+  pythonImportsCheck = [ "snscrape" ];
 
   meta = with lib; {
     homepage = "https://github.com/JustAnotherArchivist/snscrape";
diff --git a/pkgs/development/python-modules/sphinx/default.nix b/pkgs/development/python-modules/sphinx/default.nix
index d37ccd3e4489..cf792da1249e 100644
--- a/pkgs/development/python-modules/sphinx/default.nix
+++ b/pkgs/development/python-modules/sphinx/default.nix
@@ -2,6 +2,7 @@
 , buildPythonPackage
 , pythonOlder
 , fetchFromGitHub
+, fetchpatch
 # propagatedBuildInputs
 , Babel
 , alabaster
@@ -39,6 +40,14 @@ buildPythonPackage rec {
     sha256 = "sha256-0QdgHFX4r40BDHjpi9R40lXqT4n5ZgrIny+w070LZPE=";
   };
 
+  patches = [
+    (fetchpatch {
+      # Fix tests with pygments 2.10
+      url = "https://github.com/sphinx-doc/sphinx/commit/bde6c8d2effc56dc8b9098abee796167f972c306.patch";
+      sha256 = "0d0ddhgrrh7z9ix0f3zrc2gjb4d73f6ffm98zl62fzv5l4fd00lr";
+    })
+  ];
+
   propagatedBuildInputs = [
     Babel
     alabaster
diff --git a/pkgs/development/python-modules/sphinxcontrib-autoapi/default.nix b/pkgs/development/python-modules/sphinxcontrib-autoapi/default.nix
index 484b692f69f8..9f72e6f3d64f 100644
--- a/pkgs/development/python-modules/sphinxcontrib-autoapi/default.nix
+++ b/pkgs/development/python-modules/sphinxcontrib-autoapi/default.nix
@@ -13,12 +13,12 @@
 
 buildPythonPackage rec {
   pname = "sphinx-autoapi";
-  version = "1.8.1";
+  version = "1.8.4";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "842c0a8f49c824803f7edee31cb1cabd5001a987553bec7b4681283ec9e47d4a";
+    sha256 = "8c4ec5fbedc1e6e8f4692bcc4fcd1abcfb9e8dfca8a4ded60ad811a743c22ccc";
   };
 
   propagatedBuildInputs = [ astroid jinja2 pyyaml sphinx unidecode ];
diff --git a/pkgs/development/python-modules/sphinxcontrib-htmlhelp/default.nix b/pkgs/development/python-modules/sphinxcontrib-htmlhelp/default.nix
index 8ca631a2b3c9..4efdb2633f28 100644
--- a/pkgs/development/python-modules/sphinxcontrib-htmlhelp/default.nix
+++ b/pkgs/development/python-modules/sphinxcontrib-htmlhelp/default.nix
@@ -6,12 +6,12 @@
 
 buildPythonPackage rec {
   pname = "sphinxcontrib-htmlhelp";
-  version = "1.0.3";
+  version = "2.0.0";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e8f5bb7e31b2dbb25b9cc435c8ab7a79787ebf7f906155729338f3156d93659b";
+    sha256 = "f5f8bb2d0d629f398bf47d0d69c07bc13b65f75a81ad9e2f71a63d4b7a2f6db2";
   };
 
 
diff --git a/pkgs/development/python-modules/sphinxcontrib-tikz/binary-paths.patch b/pkgs/development/python-modules/sphinxcontrib-tikz/binary-paths.patch
deleted file mode 100644
index 847a6e076918..000000000000
--- a/pkgs/development/python-modules/sphinxcontrib-tikz/binary-paths.patch
+++ /dev/null
@@ -1,22 +0,0 @@
-diff --git a/sphinxcontrib/tikz.py b/sphinxcontrib/tikz.py
-index ee21113..a4f4589 100644
---- a/sphinxcontrib/tikz.py
-+++ b/sphinxcontrib/tikz.py
-@@ -242,7 +242,7 @@ def render_tikz(self, node, libs='', stringsubst=False):
-         tf.write(latex)
-         tf.close()
- 
--        system([self.builder.config.latex_engine, '--interaction=nonstopmode',
-+        system(['@texLive@/bin/pdflatex', '--interaction=nonstopmode',
-                 'tikz-%s.tex' % shasum],
-                self.builder)
- 
-@@ -281,7 +281,7 @@ def render_tikz(self, node, libs='', stringsubst=False):
-                     '-sOutputFile=%s' % outfn, '-r' + resolution + 'x' + resolution,
-                     '-f', 'tikz-%s.pdf' % shasum], self.builder)
-         elif self.builder.config.tikz_proc_suite == "pdf2svg":
--            system(['pdf2svg', 'tikz-%s.pdf' % shasum, outfn], self.builder)
-+            system(['@pdf2svg@/bin/pdf2svg', 'tikz-%s.pdf' % shasum, outfn], self.builder)
-         else:
-             self.builder._tikz_warned = True
-             raise TikzExtError('Error (tikz extension): Invalid configuration '
diff --git a/pkgs/development/python-modules/sphinxcontrib-tikz/default.nix b/pkgs/development/python-modules/sphinxcontrib-tikz/default.nix
index 19f386d7d278..cc5412fe42ff 100644
--- a/pkgs/development/python-modules/sphinxcontrib-tikz/default.nix
+++ b/pkgs/development/python-modules/sphinxcontrib-tikz/default.nix
@@ -9,19 +9,18 @@
 
 buildPythonPackage rec {
   pname = "sphinxcontrib-tikz";
-  version = "0.4.13";
+  version = "0.4.14";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "882e3ccfa202559bf77b90c93ee5eb13ec50cdd7714b3673dc6580dea7236740";
+    sha256 = "1614a45c960b80009dd42f96689122c9c0781018a0c5ec5828f4cdc5e35b11ad";
   };
 
-  patches = [
-    (substituteAll {
-      src = ./binary-paths.patch;
-      inherit texLive pdf2svg;
-    })
-  ];
+  postPatch = ''
+    substituteInPlace sphinxcontrib/tikz.py \
+      --replace "config.latex_engine" "${texLive}/bin/pdflatex" \
+      --replace "system(['pdf2svg'" "system(['${pdf2svg}/bin/pdf2svg'"
+  '';
 
   propagatedBuildInputs = [ sphinx ];
 
diff --git a/pkgs/development/python-modules/spyder-kernels/default.nix b/pkgs/development/python-modules/spyder-kernels/default.nix
index fa29236563e4..5ce41d8d7575 100644
--- a/pkgs/development/python-modules/spyder-kernels/default.nix
+++ b/pkgs/development/python-modules/spyder-kernels/default.nix
@@ -3,11 +3,11 @@
 
 buildPythonPackage rec {
   pname = "spyder-kernels";
-  version = "1.10.3";
+  version = "2.1.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "cecb0ca0115a42bab864c199a737c859a8534a510fc7edfa33dc42abcbb5287f";
+    sha256 = "6c287207c7855bb581eae66ef8d990407382d5f9caccb1e0cabf909aaaf10c9b";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/spyder/default.nix b/pkgs/development/python-modules/spyder/default.nix
index 5aaf4cb4a757..dbe54d52e3a9 100644
--- a/pkgs/development/python-modules/spyder/default.nix
+++ b/pkgs/development/python-modules/spyder/default.nix
@@ -8,13 +8,13 @@
 
 buildPythonPackage rec {
   pname = "spyder";
-  version = "4.2.5";
+  version = "5.1.1";
 
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "03159003f6ea51458e10000091e65e77888b095dba48e64ca2b36c75a648580c";
+    sha256 = "6551acfd6fedfebd1f938ef67d3db415b33540f8377e7de3f4d4a2a11dd1b915";
   };
 
   nativeBuildInputs = [ pyqtwebengine.wrapQtAppsHook ];
diff --git a/pkgs/development/python-modules/sqlite-utils/default.nix b/pkgs/development/python-modules/sqlite-utils/default.nix
index 35f7d7c07c98..8f5f7fd619c5 100644
--- a/pkgs/development/python-modules/sqlite-utils/default.nix
+++ b/pkgs/development/python-modules/sqlite-utils/default.nix
@@ -4,36 +4,38 @@
 , pythonOlder
 , click
 , click-default-group
+, dateutils
 , sqlite-fts4
 , tabulate
 , pytestCheckHook
-, pytest-runner
-, black
 , hypothesis
-, sqlite
 }:
 
 buildPythonPackage rec {
   pname = "sqlite-utils";
-  version = "3.9.1";
+  version = "3.17";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a08ed62eb269e26ae9c35b9be9cd3d395b0522157e6543128a40cc5302d8aa81";
+    sha256 = "77acd202aa568a1f6888c5d8879f306bb3f8acedc82df0df98eb615caa491abb";
   };
 
+  postPatch = ''
+    substituteInPlace setup.py \
+      --replace '"pytest-runner"' ""
+  '';
+
   propagatedBuildInputs = [
     click
     click-default-group
+    dateutils
     sqlite-fts4
     tabulate
   ];
 
   checkInputs = [
     pytestCheckHook
-    pytest-runner
-    black
     hypothesis
   ];
 
@@ -43,5 +45,4 @@ buildPythonPackage rec {
     license = licenses.asl20;
     maintainers = with maintainers; [ meatcar ];
   };
-
 }
diff --git a/pkgs/development/python-modules/ssdp/default.nix b/pkgs/development/python-modules/ssdp/default.nix
index ac39cffa393e..bd73a6abaead 100644
--- a/pkgs/development/python-modules/ssdp/default.nix
+++ b/pkgs/development/python-modules/ssdp/default.nix
@@ -1,31 +1,51 @@
 { lib
 , buildPythonPackage
-, fetchPypi
-, isPy27
+, fetchFromGitHub
 , pbr
-, pytest
-, isPy3k
+, pytestCheckHook
+, pythonOlder
+, setuptools-scm
 }:
 
 buildPythonPackage rec {
   pname = "ssdp";
-  version = "1.0.1";
-  disabled = !isPy3k;
+  version = "1.1.0";
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "0yhjqs9jyvwmba8fi72xfi9k8pxy11wkz4iywayrg71ka3la49bk";
+  disabled = pythonOlder "3.6";
+
+  src = fetchFromGitHub {
+    owner = "codingjoe";
+    repo = pname;
+    rev = version;
+    sha256 = "19d2b5frpq2qkfkpz173wpjk5jwhkjpk75p8q92nm8iv41nrzljy";
   };
 
-  buildInputs = [ pbr ];
-  checkInputs = [ pytest ];
+  SETUPTOOLS_SCM_PRETEND_VERSION = version;
 
-  # test suite uses new async primitives
-  doCheck = !isPy27;
+  nativeBuildInputs = [
+    setuptools-scm
+  ];
+
+  buildInputs = [
+    pbr
+  ];
+
+  checkInputs = [
+    pytestCheckHook
+  ];
+
+  postPatch = ''
+    substituteInPlace setup.cfg \
+      --replace "pytest-runner" "" \
+      --replace "--cov=ssdp" ""
+  '';
+
+  pythonImportsCheck = [ "ssdp" ];
 
   meta = with lib; {
+    description = "Python asyncio library for Simple Service Discovery Protocol (SSDP)";
     homepage = "https://github.com/codingjoe/ssdp";
-    description = "Python asyncio library for Simple Service Discovery Protocol (SSDP).";
     license = licenses.mit;
+    maintainers = with maintainers; [ fab ];
   };
 }
diff --git a/pkgs/development/python-modules/starlette/default.nix b/pkgs/development/python-modules/starlette/default.nix
index 3079b60564f1..e8c130692125 100644
--- a/pkgs/development/python-modules/starlette/default.nix
+++ b/pkgs/development/python-modules/starlette/default.nix
@@ -4,6 +4,8 @@
 , fetchFromGitHub
 , isPy27
 , aiofiles
+, anyio
+, contextlib2
 , graphene
 , itsdangerous
 , jinja2
@@ -12,22 +14,24 @@
 , requests
 , aiosqlite
 , databases
-, pytestCheckHook
 , pytest-asyncio
+, pytestCheckHook
+, pythonOlder
+, trio
 , typing-extensions
 , ApplicationServices
 }:
 
 buildPythonPackage rec {
   pname = "starlette";
-  version = "0.14.2";
-  disabled = isPy27;
+  version = "0.16.0";
+  disabled = pythonOlder "3.6";
 
   src = fetchFromGitHub {
     owner = "encode";
     repo = pname;
     rev = version;
-    sha256 = "0fz28czvwiww693ig9vwdja59xxs7m0yp1df32ms1hzr99666bia";
+    sha256 = "sha256-/NYhRRZdi6I7CtLCohAqK4prsSUayOxa6sBKIJhPv+w=";
   };
 
   postPatch = ''
@@ -37,19 +41,27 @@ buildPythonPackage rec {
 
   propagatedBuildInputs = [
     aiofiles
+    anyio
     graphene
     itsdangerous
     jinja2
     python-multipart
     pyyaml
     requests
-  ] ++ lib.optional stdenv.isDarwin [ ApplicationServices ];
+  ] ++ lib.optionals (pythonOlder "3.8") [
+    typing-extensions
+  ] ++ lib.optionals (pythonOlder "3.7") [
+    contextlib2
+  ] ++ lib.optional stdenv.isDarwin [
+    ApplicationServices
+  ];
 
   checkInputs = [
     aiosqlite
     databases
     pytest-asyncio
     pytestCheckHook
+    trio
     typing-extensions
   ];
 
@@ -57,8 +69,12 @@ buildPythonPackage rec {
     # fails to import graphql, but integrated graphql support is about to
     # be removed in 0.15, see https://github.com/encode/starlette/pull/1135.
     "tests/test_graphql.py"
-    # contextfunction was removed in Jinja 3.1
-    "tests/test_templates.py"
+  ];
+
+  disabledTests = [
+    # asserts fail due to inclusion of br in Accept-Encoding
+    "test_websocket_headers"
+    "test_request_headers"
   ];
 
   pythonImportsCheck = [ "starlette" ];
diff --git a/pkgs/development/python-modules/sure/default.nix b/pkgs/development/python-modules/sure/default.nix
index ee21e9c45168..b8bb9a36586a 100644
--- a/pkgs/development/python-modules/sure/default.nix
+++ b/pkgs/development/python-modules/sure/default.nix
@@ -9,12 +9,12 @@
 
 buildPythonPackage rec {
   pname = "sure";
-  version = "1.4.11";
+  version = "2.0.0";
   disabled = isPyPy;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3c8d5271fb18e2c69e2613af1ad400d8df090f1456081635bd3171847303cdaa";
+    sha256 = "34ae88c846046742ef074036bf311dc90ab152b7bc09c342b281cebf676727a2";
   };
 
   buildInputs = [ rednose ];
diff --git a/pkgs/development/python-modules/tableaudocumentapi/default.nix b/pkgs/development/python-modules/tableaudocumentapi/default.nix
index 5260a678e8c7..56a3b27e7b96 100644
--- a/pkgs/development/python-modules/tableaudocumentapi/default.nix
+++ b/pkgs/development/python-modules/tableaudocumentapi/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "tableaudocumentapi";
-  version = "0.6";
+  version = "0.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "fc6d44b62cf6ea29916c073686e2f9f35c9902eccd57b8493f8d44a59a2f60d9";
+    sha256 = "5b1d04817a0fba43d58e1ce23c64ad8dfe54dc029ba5ccae3908944555bb13e0";
   };
 
   # tests not inclued with release
diff --git a/pkgs/development/python-modules/tempora/default.nix b/pkgs/development/python-modules/tempora/default.nix
index 8da8d622a7b3..7bd7605fc3ff 100644
--- a/pkgs/development/python-modules/tempora/default.nix
+++ b/pkgs/development/python-modules/tempora/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "tempora";
-  version = "4.0.2";
+  version = "4.1.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "10fdc29bf85fa0df39a230a225bb6d093982fc0825b648a414bbc06bddd79909";
+    sha256 = "c54da0f05405f04eb67abbb1dff4448fd91428b58cb00f0f645ea36f6a927950";
   };
 
   disabled = pythonOlder "3.2";
diff --git a/pkgs/development/python-modules/tensorboard-plugin-profile/default.nix b/pkgs/development/python-modules/tensorboard-plugin-profile/default.nix
index 1ae1aa471be5..843b9d6c3199 100644
--- a/pkgs/development/python-modules/tensorboard-plugin-profile/default.nix
+++ b/pkgs/development/python-modules/tensorboard-plugin-profile/default.nix
@@ -6,14 +6,15 @@
 
 buildPythonPackage rec {
   pname = "tensorboard_plugin_profile";
-  version = "2.4.0";
+  version = "2.5.0";
   format = "wheel";
 
   src = fetchPypi {
     inherit pname version;
     format = "wheel";
+    dist = "py3";
     python = "py3";
-    sha256 = "0z6dcjvkk3pzmmmjxi2ybawnfshz5qa3ga92kqj69ld1g9k3i9bj";
+    sha256 = "16jch9py98h7wrffdiz6j0i3kdykxdp5m0kfxr1fxy2phqanpjqk";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/terminado/default.nix b/pkgs/development/python-modules/terminado/default.nix
index 27c159349b0a..aff355d963ce 100644
--- a/pkgs/development/python-modules/terminado/default.nix
+++ b/pkgs/development/python-modules/terminado/default.nix
@@ -7,11 +7,11 @@
 
 buildPythonPackage rec {
   pname = "terminado";
-  version = "0.10.1";
+  version = "0.11.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "89d5dac2f4e2b39758a0ff9a3b643707c95a020a6df36e70583b88297cd59cbe";
+    sha256 = "962b402edbb480718054dc37027bada293972ecadfb587b89f01e2b8660a2132";
   };
 
   propagatedBuildInputs = [ ptyprocess tornado ];
diff --git a/pkgs/development/python-modules/termplotlib/default.nix b/pkgs/development/python-modules/termplotlib/default.nix
index dae40dcb993a..492d51dcb2ca 100644
--- a/pkgs/development/python-modules/termplotlib/default.nix
+++ b/pkgs/development/python-modules/termplotlib/default.nix
@@ -9,13 +9,13 @@
 
 buildPythonPackage rec {
   pname = "termplotlib";
-  version = "0.3.5";
+  version = "0.3.8";
 
   src = fetchFromGitHub {
     owner = "nschloe";
     repo = pname;
     rev = "v${version}";
-    sha256 = "1z6bw6lkbrgjyq3ndsx20gwpai4scm1q9rjh4rdz0rvja4jdcv3z";
+    sha256 = "10k70pb7554cc2zwkcgxfak8nb7iqqw6njbnaqfdz07l4v9f6smm";
   };
 
   format = "pyproject";
diff --git a/pkgs/development/python-modules/tern/default.nix b/pkgs/development/python-modules/tern/default.nix
index 0468ee6f84b1..b8aee5ab9315 100644
--- a/pkgs/development/python-modules/tern/default.nix
+++ b/pkgs/development/python-modules/tern/default.nix
@@ -16,11 +16,11 @@
 
 buildPythonPackage rec {
   pname = "tern";
-  version = "2.6.1";
+  version = "2.7.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "749c18ef493ebe3ac28624b2b26c6e38f77de2afd6a6579d2c92393d8fbdbd46";
+    sha256 = "cfd59431cafd6adf05ccb94be964098d9301f83a03bf715def7861811e4a4b74";
   };
 
   preBuild = ''
diff --git a/pkgs/development/python-modules/teslajsonpy/default.nix b/pkgs/development/python-modules/teslajsonpy/default.nix
index 750b070804c3..6fefda407f90 100644
--- a/pkgs/development/python-modules/teslajsonpy/default.nix
+++ b/pkgs/development/python-modules/teslajsonpy/default.nix
@@ -14,14 +14,14 @@
 
 buildPythonPackage rec {
   pname = "teslajsonpy";
-  version = "0.18.3";
+  version = "0.19.0";
   format = "pyproject";
 
   src = fetchFromGitHub {
     owner = "zabuldon";
     repo = pname;
     rev = "v${version}";
-    sha256 = "1hdc5gm6dg1vw6qfs3z6mg2m94scrvjphj0lin6pi8n3zqj1h26k";
+    sha256 = "04ihjxysfmppwa7rnz86nd89wrqks2gwvcza8707yddzfp5hh8id";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/testtools/default.nix b/pkgs/development/python-modules/testtools/default.nix
index 8ef3d9c4320f..a07117a1e46d 100644
--- a/pkgs/development/python-modules/testtools/default.nix
+++ b/pkgs/development/python-modules/testtools/default.nix
@@ -11,11 +11,11 @@
 
 buildPythonPackage rec {
   pname = "testtools";
-  version = "2.4.0";
+  version = "2.5.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "64c974a6cca4385d05f4bbfa2deca1c39ce88ede31c3448bee86a7259a9a61c8";
+    sha256 = "57c13433d94f9ffde3be6534177d10fb0c1507cc499319128958ca91a65cb23f";
   };
 
   propagatedBuildInputs = [ pbr python_mimeparse extras unittest2 ];
diff --git a/pkgs/development/python-modules/texttable/default.nix b/pkgs/development/python-modules/texttable/default.nix
index a8c6d9dcfda8..b104bd845962 100644
--- a/pkgs/development/python-modules/texttable/default.nix
+++ b/pkgs/development/python-modules/texttable/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "texttable";
-  version = "1.6.3";
+  version = "1.6.4";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "ce0faf21aa77d806bbff22b107cc22cce68dc9438f97a2df32c93e9afa4ce436";
+    sha256 = "42ee7b9e15f7b225747c3fa08f43c5d6c83bc899f80ff9bae9319334824076e9";
   };
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/tifffile/default.nix b/pkgs/development/python-modules/tifffile/default.nix
index 40654366ea21..236f3443ca6b 100644
--- a/pkgs/development/python-modules/tifffile/default.nix
+++ b/pkgs/development/python-modules/tifffile/default.nix
@@ -13,11 +13,11 @@
 
 buildPythonPackage rec {
   pname = "tifffile";
-  version = "2021.6.14";
+  version = "2021.8.8";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a2f83d82800a8d83cbd04340f9d65a6873a970874947a6b823b1b1238e84cba6";
+    sha256 = "8260f31c4700143e8374ff6cde5cef7fe54fc9b7313afe88329f407881901dc5";
   };
 
   patches = lib.optional isPy27 ./python2-regex-compat.patch;
diff --git a/pkgs/development/python-modules/tomli/default.nix b/pkgs/development/python-modules/tomli/default.nix
index c658339dcd9c..79cd5a4f500c 100644
--- a/pkgs/development/python-modules/tomli/default.nix
+++ b/pkgs/development/python-modules/tomli/default.nix
@@ -1,9 +1,8 @@
 { lib
 , buildPythonPackage
+, callPackage
 , fetchFromGitHub
 , flit-core
-, pytestCheckHook
-, python-dateutil
 }:
 
 buildPythonPackage rec {
@@ -11,6 +10,11 @@ buildPythonPackage rec {
   version = "1.1.0";
   format = "pyproject";
 
+  outputs = [
+    "out"
+    "testsout"
+  ];
+
   src = fetchFromGitHub {
     owner = "hukkin";
     repo = pname;
@@ -20,17 +24,24 @@ buildPythonPackage rec {
 
   nativeBuildInputs = [ flit-core ];
 
-  checkInputs = [
-    pytestCheckHook
-    python-dateutil
-  ];
+  postInstall = ''
+    mkdir $testsout
+    cp -R benchmark/ pyproject.toml tests/ $testsout/
+  '';
 
   pythonImportsCheck = [ "tomli" ];
 
+  # check in passthru.tests.pytest to escape infinite recursion with setuptools-scm
+  doCheck = false;
+
+  passthru.tests = {
+    pytest = callPackage ./tests.nix { };
+  };
+
   meta = with lib; {
     description = "A Python library for parsing TOML, fully compatible with TOML v1.0.0";
     homepage = "https://github.com/hukkin/tomli";
     license = licenses.mit;
-    maintainers = with maintainers; [ veehaitch ];
+    maintainers = with maintainers; [ veehaitch SuperSandro2000 ];
   };
 }
diff --git a/pkgs/development/python-modules/tomli/tests.nix b/pkgs/development/python-modules/tomli/tests.nix
new file mode 100644
index 000000000000..5d3d67dbd128
--- /dev/null
+++ b/pkgs/development/python-modules/tomli/tests.nix
@@ -0,0 +1,21 @@
+{ buildPythonPackage
+, tomli
+, pytestCheckHook
+, python-dateutil
+}:
+
+buildPythonPackage rec {
+  pname = "tomli-tests";
+  inherit (tomli) version;
+
+  src = tomli.testsout;
+
+  dontBuild = true;
+  dontInstall = true;
+
+  checkInputs = [
+    pytestCheckHook
+    python-dateutil
+    tomli
+  ];
+}
diff --git a/pkgs/development/python-modules/towncrier/default.nix b/pkgs/development/python-modules/towncrier/default.nix
index 6b699a2fbc24..83215f5e0af3 100644
--- a/pkgs/development/python-modules/towncrier/default.nix
+++ b/pkgs/development/python-modules/towncrier/default.nix
@@ -3,6 +3,7 @@
 , click-default-group
 , incremental
 , jinja2
+, mock
 , pytestCheckHook
 , toml
 , twisted
@@ -11,11 +12,11 @@
 
 buildPythonPackage rec {
   pname = "towncrier";
-  version = "19.9.0";
+  version = "21.3.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "19916889879353a8863f3de8cb1ef19b305a0b5cfd9d36159d76ca2fef08e9aa";
+    sha256 = "6eed0bc924d72c98c000cb8a64de3bd566e5cb0d11032b73fcccf8a8f956ddfe";
   };
 
   propagatedBuildInputs = [
@@ -28,7 +29,12 @@ buildPythonPackage rec {
 
   # zope.interface collision
   doCheck = !isPy27;
-  checkInputs = [ git twisted pytestCheckHook ];
+  checkInputs = [
+    git
+    mock
+    twisted
+    pytestCheckHook
+  ];
   pythonImportsCheck = [ "towncrier" ];
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/tox/default.nix b/pkgs/development/python-modules/tox/default.nix
index 035bb9701bb5..c660327ad72e 100644
--- a/pkgs/development/python-modules/tox/default.nix
+++ b/pkgs/development/python-modules/tox/default.nix
@@ -13,7 +13,7 @@
 
 buildPythonPackage rec {
   pname = "tox";
-  version = "3.23.1";
+  version = "3.24.3";
 
   buildInputs = [ setuptools-scm ];
   propagatedBuildInputs = [ packaging pluggy py six virtualenv toml filelock ];
@@ -22,7 +22,7 @@ buildPythonPackage rec {
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "307a81ddb82bd463971a273f33e9533a24ed22185f27db8ce3386bff27d324e3";
+    sha256 = "c6c4e77705ada004283610fd6d9ba4f77bc85d235447f875df9f0ba1bc23b634";
   };
 
   meta = with lib; {
diff --git a/pkgs/development/python-modules/tqdm/default.nix b/pkgs/development/python-modules/tqdm/default.nix
index fe2eb35d4df7..babea4357a79 100644
--- a/pkgs/development/python-modules/tqdm/default.nix
+++ b/pkgs/development/python-modules/tqdm/default.nix
@@ -14,11 +14,11 @@
 
 buildPythonPackage rec {
   pname = "tqdm";
-  version = "4.61.1";
+  version = "4.62.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "24be966933e942be5f074c29755a95b315c69a91f839a29139bf26ffffe2d3fd";
+    sha256 = "a4d6d112e507ef98513ac119ead1159d286deab17dffedd96921412c2d236ff5";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/traitlets/default.nix b/pkgs/development/python-modules/traitlets/default.nix
index 3bc05897af66..23412d0a6940 100644
--- a/pkgs/development/python-modules/traitlets/default.nix
+++ b/pkgs/development/python-modules/traitlets/default.nix
@@ -13,12 +13,12 @@
 
 buildPythonPackage rec {
   pname = "traitlets";
-  version = "5.0.5";
+  version = "5.1.0";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "178f4ce988f69189f7e523337a3e11d91c786ded9360174a3d9ca83e79bc5396";
+    sha256 = "bd382d7ea181fbbcce157c133db9a829ce06edffe097bcf3ab945b435452b46d";
   };
 
   checkInputs = [ glibcLocales pytest mock ];
diff --git a/pkgs/development/python-modules/trytond/default.nix b/pkgs/development/python-modules/trytond/default.nix
index d5ddf8f58802..75e1ee68e4b3 100644
--- a/pkgs/development/python-modules/trytond/default.nix
+++ b/pkgs/development/python-modules/trytond/default.nix
@@ -23,12 +23,12 @@
 
 buildPythonApplication rec {
   pname = "trytond";
-  version = "5.8.9";
+  version = "6.0.5";
   disabled = pythonOlder "3.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "5f14e9615ff91e18c146c74eb4c1cd56112662361a52c73389f15baced0bef18";
+    sha256 = "3ccb98dbf905d99991ed0151e13c91cd9267e4aa104fa40097df4e02580dadfc";
   };
 
   # Tells the tests which database to use
diff --git a/pkgs/development/python-modules/twine/default.nix b/pkgs/development/python-modules/twine/default.nix
index da5c4a9c3f51..f5809b0a9b90 100644
--- a/pkgs/development/python-modules/twine/default.nix
+++ b/pkgs/development/python-modules/twine/default.nix
@@ -14,12 +14,13 @@
 
 buildPythonPackage rec {
   pname = "twine";
-  version = "3.4.1";
+  version = "3.4.2";
+  format = "pyproject";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a56c985264b991dc8a8f4234eb80c5af87fa8080d0c224ad8f2cd05a2c22e83b";
+    sha256 = "4caec0f1ed78dc4c9b83ad537e453d03ce485725f2aea57f1bb3fdde78dae936";
   };
 
   nativeBuildInputs = [ setuptools-scm ];
diff --git a/pkgs/development/python-modules/types-pytz/default.nix b/pkgs/development/python-modules/types-pytz/default.nix
index 2fc5cc0d4503..4b3f9c1726c8 100644
--- a/pkgs/development/python-modules/types-pytz/default.nix
+++ b/pkgs/development/python-modules/types-pytz/default.nix
@@ -5,11 +5,11 @@
 
 buildPythonPackage rec {
   pname = "types-pytz";
-  version = "2021.1.0";
+  version = "2021.1.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0hzjz6wgzfyybcfli4rpmfxk49cn6x3slbs2xdmlnckvlahs5pxd";
+    sha256 = "448828a06f2aaa840e57364d866c661645a045e532f817e4f10c8c3ab2b66651";
   };
 
   # Modules doesn't have tests
diff --git a/pkgs/development/python-modules/typing-extensions/default.nix b/pkgs/development/python-modules/typing-extensions/default.nix
index fd8a25a485b9..939ca25eb1a3 100644
--- a/pkgs/development/python-modules/typing-extensions/default.nix
+++ b/pkgs/development/python-modules/typing-extensions/default.nix
@@ -4,11 +4,11 @@ let
 
 in buildPythonPackage rec {
   pname = "typing_extensions";
-  version = "3.10.0.0";
+  version = "3.10.0.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "50b6f157849174217d0656f99dc82fe932884fb250826c18350e159ec6cdf342";
+    sha256 = "49f75d16ff11f1cd258e1b988ccff82a3ca5570217d7ad8c5f48205dd99a677e";
   };
 
   checkInputs = lib.optional (pythonOlder "3.5") typing;
diff --git a/pkgs/development/python-modules/tzlocal/default.nix b/pkgs/development/python-modules/tzlocal/default.nix
index c5514cfa53a4..363e1d12a55e 100644
--- a/pkgs/development/python-modules/tzlocal/default.nix
+++ b/pkgs/development/python-modules/tzlocal/default.nix
@@ -3,7 +3,7 @@
 
 buildPythonPackage rec {
   pname = "tzlocal";
-  version = "2.1";
+  version = "2.1"; # version needs to be compatible with APScheduler
 
   propagatedBuildInputs = [ pytz ];
 
diff --git a/pkgs/development/python-modules/uvloop/default.nix b/pkgs/development/python-modules/uvloop/default.nix
index a762ec55ee36..c7e11ab6c258 100644
--- a/pkgs/development/python-modules/uvloop/default.nix
+++ b/pkgs/development/python-modules/uvloop/default.nix
@@ -15,12 +15,12 @@
 
 buildPythonPackage rec {
   pname = "uvloop";
-  version = "0.15.2";
+  version = "0.16.0";
   disabled = pythonOlder "3.7";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "2bb0624a8a70834e54dde8feed62ed63b50bad7a1265c40d6403a2ac447bce01";
+    sha256 = "f74bc20c7b67d1c27c72601c78cf95be99d5c2cdd4514502b4f3eb0933ff1228";
   };
 
   buildInputs = [
diff --git a/pkgs/development/python-modules/virtualenv/default.nix b/pkgs/development/python-modules/virtualenv/default.nix
index 2bcfa88b6ae4..10e1ebbc87bc 100644
--- a/pkgs/development/python-modules/virtualenv/default.nix
+++ b/pkgs/development/python-modules/virtualenv/default.nix
@@ -1,6 +1,9 @@
-{ buildPythonPackage
-, appdirs
-, contextlib2
+{ stdenv
+, lib
+, buildPythonPackage
+, pythonOlder
+, isPy27
+, backports-entry-points-selectable
 , cython
 , distlib
 , fetchPypi
@@ -8,26 +11,23 @@
 , flaky
 , importlib-metadata
 , importlib-resources
-, isPy27
-, lib
 , pathlib2
+, platformdirs
 , pytest-freezegun
 , pytest-mock
 , pytest-timeout
 , pytestCheckHook
-, pythonOlder
 , setuptools-scm
 , six
-, stdenv
 }:
 
 buildPythonPackage rec {
   pname = "virtualenv";
-  version = "20.4.7";
+  version = "20.7.2";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "14fdf849f80dbb29a4eb6caa9875d476ee2a5cf76a5f5415fa2f1606010ab467";
+    sha256 = "9ef4e8ee4710826e98ff3075c9a4739e2cb1040de6a2a8d35db0055840dc96a0";
   };
 
   nativeBuildInputs = [
@@ -35,13 +35,12 @@ buildPythonPackage rec {
   ];
 
   propagatedBuildInputs = [
-    appdirs
+    backports-entry-points-selectable
     distlib
     filelock
+    platformdirs
     six
-  ] ++ lib.optionals isPy27 [
-    contextlib2
-  ] ++ lib.optionals (isPy27 && !stdenv.hostPlatform.isWindows) [
+  ] ++ lib.optionals (pythonOlder "3.4" && !stdenv.hostPlatform.isWindows) [
     pathlib2
   ] ++ lib.optionals (pythonOlder "3.7") [
     importlib-resources
diff --git a/pkgs/development/python-modules/vispy/default.nix b/pkgs/development/python-modules/vispy/default.nix
index 849f25ef0df3..9ebbfcd77e87 100644
--- a/pkgs/development/python-modules/vispy/default.nix
+++ b/pkgs/development/python-modules/vispy/default.nix
@@ -1,15 +1,26 @@
-{ lib, buildPythonPackage, substituteAll, stdenv,
-  fetchPypi, numpy, cython, freetype-py, fontconfig, libGL,
-  setuptools-scm, setuptools-scm-git-archive
-  }:
+{ lib
+, stdenv
+, buildPythonPackage
+, substituteAll
+, fetchPypi
+, cython
+, fontconfig
+, freetype-py
+, hsluv
+, kiwisolver
+, libGL
+, numpy
+, setuptools-scm
+, setuptools-scm-git-archive
+}:
 
 buildPythonPackage rec {
   pname = "vispy";
-  version = "0.6.6";
+  version = "0.8.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "6f3c4d00be9e6761c046d520a86693d78a0925d47eeb2fc095e95dac776f74ee";
+    sha256 = "6e482e68487f5384205d349f288580d6287fd690df4cdc3ad4c573afc39990f1";
   };
 
   patches = [
@@ -21,15 +32,37 @@ buildPythonPackage rec {
   ];
 
   nativeBuildInputs = [
-    cython setuptools-scm setuptools-scm-git-archive
+    cython
+    setuptools-scm
+    setuptools-scm-git-archive
+  ];
+
+  buildInputs = [
+    libGL
   ];
 
   propagatedBuildInputs = [
-    numpy freetype-py fontconfig libGL
+    fontconfig
+    freetype-py
+    hsluv
+    kiwisolver
+    numpy
   ];
 
   doCheck = false;  # otherwise runs OSX code on linux.
-  pythonImportsCheck = [ "vispy" ];
+
+  pythonImportsCheck = [
+    "vispy"
+    "vispy.color"
+    "vispy.geometry"
+    "vispy.gloo"
+    "vispy.glsl"
+    "vispy.io"
+    "vispy.plot"
+    "vispy.scene"
+    "vispy.util"
+    "vispy.visuals"
+  ];
 
   meta = with lib; {
     homepage = "https://vispy.org/index.html";
diff --git a/pkgs/development/python-modules/vivisect/default.nix b/pkgs/development/python-modules/vivisect/default.nix
index 43e54bda9d6c..5dc8bc2254d4 100644
--- a/pkgs/development/python-modules/vivisect/default.nix
+++ b/pkgs/development/python-modules/vivisect/default.nix
@@ -10,12 +10,12 @@
 }:
 buildPythonPackage rec {
   pname = "vivisect";
-  version = "0.2.1";
+  version = "1.0.4";
   disabled = isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8fc4d2097a1d0d8d97aa8c540984cb52432df759f04f2281a21a4e1b7d1a95a7";
+    sha256 = "bd47b2cf5874cd2f74e6c36b8a97bf301785bacf9ac0297bbe78ec1b8c86c755";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/vowpalwabbit/default.nix b/pkgs/development/python-modules/vowpalwabbit/default.nix
index 0a75600bb0f0..1a1c6a33acb3 100644
--- a/pkgs/development/python-modules/vowpalwabbit/default.nix
+++ b/pkgs/development/python-modules/vowpalwabbit/default.nix
@@ -15,11 +15,11 @@
 
 buildPythonPackage rec {
   pname = "vowpalwabbit";
-  version = "8.10.2";
+  version = "8.11.0";
 
   src = fetchPypi{
     inherit pname version;
-    sha256 = "e9f7d525a6e88ebff41406409a5c31f79bb008f524fc63a61dc74bac6a1ac887";
+    sha256 = "cfde0515a3fa4d224aad5461135372f3441ae1a64717ae6bff5e23509d70b0bd";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/wasmer/default.nix b/pkgs/development/python-modules/wasmer/default.nix
index d3881032af13..dff14d15b901 100644
--- a/pkgs/development/python-modules/wasmer/default.nix
+++ b/pkgs/development/python-modules/wasmer/default.nix
@@ -1,45 +1,99 @@
-{ lib
-, stdenv
+{ stdenv
+, lib
 , rustPlatform
+, callPackage
 , fetchFromGitHub
 , buildPythonPackage
 , libiconv
+, llvm_11
+, libffi
+, libxml2
+, ncurses
+, zlib
 }:
 
-buildPythonPackage rec {
-  pname = "wasmer";
-  version = "1.0.0";
+let
+  common =
+    { pname
+    , buildAndTestSubdir
+    , cargoHash
+    , extraNativeBuildInputs ? [ ]
+    , extraBuildInputs ? [ ]
+    }: buildPythonPackage rec {
+      inherit pname;
+      version = "1.0.0";
+      format = "pyproject";
 
-  src = fetchFromGitHub {
-    owner = "wasmerio";
-    repo = "wasmer-python";
-    rev = version;
-    hash = "sha256-I1GfjLaPYMIHKh2m/5IQepUsJNiVUEJg49wyuuzUYtY=";
+      outputs = [ "out" ] ++ lib.optional (pname == "wasmer") "testsout";
+
+      src = fetchFromGitHub {
+        owner = "wasmerio";
+        repo = "wasmer-python";
+        rev = version;
+        hash = "sha256-I1GfjLaPYMIHKh2m/5IQepUsJNiVUEJg49wyuuzUYtY=";
+      };
+
+      cargoDeps = rustPlatform.fetchCargoTarball {
+        inherit src;
+        name = "${pname}-${version}";
+        sha256 = cargoHash;
+      };
+
+      nativeBuildInputs = (with rustPlatform; [ cargoSetupHook maturinBuildHook ])
+        ++ extraNativeBuildInputs;
+
+      buildInputs = lib.optionals stdenv.isDarwin [ libiconv ]
+        ++ extraBuildInputs;
+
+      inherit buildAndTestSubdir;
+
+      postInstall = lib.optionalString (pname == "wasmer") ''
+        mkdir $testsout
+        cp -R tests $testsout/tests
+      '';
+
+      # check in passthru.tests.pytest because all packages are required to run the tests
+      doCheck = false;
+
+      passthru.tests = lib.optionalAttrs (pname == "wasmer") {
+        pytest = callPackage ./tests.nix { };
+      };
+
+      pythonImportsCheck = [ "${lib.replaceStrings ["-"] ["_"] pname}" ];
+
+      meta = with lib; {
+        description = "Python extension to run WebAssembly binaries";
+        homepage = "https://github.com/wasmerio/wasmer-python";
+        license = licenses.mit;
+        platforms = platforms.unix;
+        maintainers = with maintainers; [ SuperSandro2000 ];
+      };
+    };
+in
+rec {
+  wasmer = common {
+    pname = "wasmer";
+    buildAndTestSubdir = "packages/api";
+    cargoHash = "sha256-txOOia1C4W+nsXuXp4EytEn82CFfSmiOYwRLC4WPImc=";
   };
 
-  cargoDeps = rustPlatform.fetchCargoTarball {
-    inherit src;
-    name = "${pname}-${version}";
-    hash = "sha256-txOOia1C4W+nsXuXp4EytEn82CFfSmiOYwRLC4WPImc=";
+  wasmer-compiler-cranelift = common {
+    pname = "wasmer-compiler-cranelift";
+    buildAndTestSubdir = "packages/compiler-cranelift";
+    cargoHash = "sha256-cHgAUwqnbQV3E5nUYGYQ48ntbIFfq4JXfU5IrSFZ3zI=";
   };
 
-  format = "pyproject";
+  wasmer-compiler-llvm = common {
+    pname = "wasmer-compiler-llvm";
+    buildAndTestSubdir = "packages/compiler-llvm";
+    cargoHash = "sha256-Jm22CC5S3pN/vdVvsGZdvtoAgPzWVLto8wavSJdxY3A=";
+    extraNativeBuildInputs = [ llvm_11 ];
+    extraBuildInputs = [ libffi libxml2.out ncurses zlib ];
+  };
 
-  nativeBuildInputs = with rustPlatform; [ cargoSetupHook maturinBuildHook ];
-
-  buildInputs = lib.optionals stdenv.isDarwin [ libiconv ];
-
-  buildAndTestSubdir = "packages/api";
-
-  doCheck = false;
-
-  pythonImportsCheck = [ "wasmer" ];
-
-  meta = with lib; {
-    description = "Python extension to run WebAssembly binaries";
-    homepage = "https://github.com/wasmerio/wasmer-python";
-    license = licenses.mit;
-    platforms = platforms.unix;
-    maintainers = with maintainers; [ SuperSandro2000 ];
+  wasmer-compiler-singlepass = common {
+    pname = "wasmer-compiler-singlepass";
+    buildAndTestSubdir = "packages/compiler-singlepass";
+    cargoHash = "sha256-lmqEo3+jYoN+4EEYphcoE4b84jdFcvYVycjrJ956Bh8=";
   };
 }
diff --git a/pkgs/development/python-modules/wasmer/tests.nix b/pkgs/development/python-modules/wasmer/tests.nix
new file mode 100644
index 000000000000..bdb3adfe93ce
--- /dev/null
+++ b/pkgs/development/python-modules/wasmer/tests.nix
@@ -0,0 +1,25 @@
+{ buildPythonPackage
+, wasmer
+, pytestCheckHook
+, wasmer-compiler-cranelift
+, wasmer-compiler-llvm
+, wasmer-compiler-singlepass
+}:
+
+buildPythonPackage rec {
+  pname = "wasmer-tests";
+  inherit (wasmer) version;
+
+  src = wasmer.testsout;
+
+  dontBuild = true;
+  dontInstall = true;
+
+  checkInputs = [
+    pytestCheckHook
+    wasmer
+    wasmer-compiler-cranelift
+    wasmer-compiler-llvm
+    wasmer-compiler-singlepass
+  ];
+}
diff --git a/pkgs/development/python-modules/watchdog/default.nix b/pkgs/development/python-modules/watchdog/default.nix
index 921ed5af4aa1..7dab01b3ca09 100644
--- a/pkgs/development/python-modules/watchdog/default.nix
+++ b/pkgs/development/python-modules/watchdog/default.nix
@@ -13,11 +13,11 @@
 
 buildPythonPackage rec {
   pname = "watchdog";
-  version = "2.1.3";
+  version = "2.1.5";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-5SNqjoYCq220uHNmTC01bDZas8rJb73sSXCtYWQV3UU=";
+    sha256 = "5563b005907613430ef3d4aaac9c78600dd5704e84764cb6deda4b3d72807f09";
   };
 
   buildInputs = lib.optionals stdenv.isDarwin [ CoreServices ];
diff --git a/pkgs/development/python-modules/webargs/default.nix b/pkgs/development/python-modules/webargs/default.nix
index 6db909992f48..63ad60c9f084 100644
--- a/pkgs/development/python-modules/webargs/default.nix
+++ b/pkgs/development/python-modules/webargs/default.nix
@@ -4,12 +4,12 @@
 
 buildPythonPackage rec {
   pname = "webargs";
-  version = "8.0.0";
+  version = "8.0.1";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0xy6na8axc5wnp2wg3kvqbpl2iv0hx0rsnlrmrgkgp88znx6cmjn";
+    sha256 = "bcce022250ee97cfbb0ad07b02388ac90a226ef4b479ec84317152345a565614";
   };
 
   pythonImportsCheck = [
diff --git a/pkgs/development/python-modules/werkzeug/default.nix b/pkgs/development/python-modules/werkzeug/default.nix
index d3dce5018d97..898fa4556ec3 100644
--- a/pkgs/development/python-modules/werkzeug/default.nix
+++ b/pkgs/development/python-modules/werkzeug/default.nix
@@ -8,15 +8,16 @@
 , pytest-timeout
 , pytest-xprocess
 , pytestCheckHook
- }:
+}:
 
 buildPythonPackage rec {
-  pname = "Werkzeug";
+  pname = "werkzeug";
   version = "2.0.1";
   disabled = pythonOlder "3.6";
 
   src = fetchPypi {
-    inherit pname version;
+    pname = "Werkzeug";
+    inherit version;
     sha256 = "0hlwawnn8c41f254qify5jnjj8xb97n294h09bqimzqhs0qdpq8x";
   };
 
diff --git a/pkgs/development/python-modules/xarray/default.nix b/pkgs/development/python-modules/xarray/default.nix
index 675461a63cc6..ee07adeb9d5b 100644
--- a/pkgs/development/python-modules/xarray/default.nix
+++ b/pkgs/development/python-modules/xarray/default.nix
@@ -11,12 +11,12 @@
 
 buildPythonPackage rec {
   pname = "xarray";
-  version = "0.18.2";
+  version = "0.19.0";
   disabled = !isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "5d2e72a228286fcf60f66e16876bd27629a1a70bf64822c565f16515c4d10284";
+    sha256 = "3a365ce09127fc841ba88baa63f37ca61376ffe389a6c5e66d52f2c88c23a62b";
   };
 
   nativeBuildInputs = [ setuptools-scm ];
diff --git a/pkgs/development/python-modules/xml2rfc/default.nix b/pkgs/development/python-modules/xml2rfc/default.nix
index c975218e5b1d..b623fc37c224 100644
--- a/pkgs/development/python-modules/xml2rfc/default.nix
+++ b/pkgs/development/python-modules/xml2rfc/default.nix
@@ -4,12 +4,12 @@
 
 buildPythonPackage rec {
   pname = "xml2rfc";
-  version = "3.8.0";
+  version = "3.9.1";
   disabled = pythonAtLeast "3.9";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "8e25a9d73acf57ade798fc67841277dbbdb81ced390e6f84362370305b127426";
+    sha256 = "76cee167e81fc3cc0e0cc696fe58cadd039e19a774c8f4d2e5c0fea724c7aaca";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/xmlsec/default.nix b/pkgs/development/python-modules/xmlsec/default.nix
index b8c60f1b6425..c94f018382a6 100644
--- a/pkgs/development/python-modules/xmlsec/default.nix
+++ b/pkgs/development/python-modules/xmlsec/default.nix
@@ -9,7 +9,6 @@
 , xmlsec
 , pkgconfig
 , setuptools-scm
-, toml
 , lxml
 , hypothesis
 }:
@@ -28,7 +27,7 @@ buildPythonPackage rec {
     ./reset-lxml-in-tests.patch
   ];
 
-  nativeBuildInputs = [ pkg-config pkgconfig setuptools-scm toml ];
+  nativeBuildInputs = [ pkg-config pkgconfig setuptools-scm ];
 
   buildInputs = [ xmlsec libxslt libxml2 libtool ];
 
diff --git a/pkgs/development/python-modules/yamlloader/default.nix b/pkgs/development/python-modules/yamlloader/default.nix
index d2b66cb073d7..97da02102c7f 100644
--- a/pkgs/development/python-modules/yamlloader/default.nix
+++ b/pkgs/development/python-modules/yamlloader/default.nix
@@ -4,11 +4,11 @@
 
 buildPythonPackage rec {
   pname = "yamlloader";
-  version = "1.0.0";
+  version = "1.1.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "e96dc3dc6895d814c330c054c966d993fc81ef1dbf5a30a4bdafeb256359e058";
+    sha256 = "8a297c7a197683ba02e5e2b882ffd6c6180d01bdefb534b69cd3962df020bfe6";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/yt/default.nix b/pkgs/development/python-modules/yt/default.nix
index 42bde9909b8c..9611b2722295 100644
--- a/pkgs/development/python-modules/yt/default.nix
+++ b/pkgs/development/python-modules/yt/default.nix
@@ -15,12 +15,12 @@
 
 buildPythonPackage rec {
   pname = "yt";
-  version = "3.6.1";
+  version = "4.0.1";
   disabled = isPy3k;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "be454f9d05dcbe0623328b4df43a1bfd1f0925e516be97399710452931a19bb0";
+    sha256 = "6219cbf971871320a13679a57722c0363e50db5e6d4d64ea9d197461b2a7f70f";
   };
 
   buildInputs = [
diff --git a/pkgs/development/python-modules/ytmusicapi/default.nix b/pkgs/development/python-modules/ytmusicapi/default.nix
index 6ec5fda2ca58..77a579eba9c7 100644
--- a/pkgs/development/python-modules/ytmusicapi/default.nix
+++ b/pkgs/development/python-modules/ytmusicapi/default.nix
@@ -7,13 +7,13 @@
 
 buildPythonPackage rec {
   pname = "ytmusicapi";
-  version = "0.18.0";
+  version = "0.19.1";
 
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-RH0ballPSZQvesdUEsulnBkbbzVA2YrGWhMzRFvuwW0=";
+    sha256 = "1b8a050e2208b3d05359106d8c44c3d62e60edf6753529bd8a207788a6caeb95";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/zarr/default.nix b/pkgs/development/python-modules/zarr/default.nix
index 9fc5589d281d..a26fa1dfef3c 100644
--- a/pkgs/development/python-modules/zarr/default.nix
+++ b/pkgs/development/python-modules/zarr/default.nix
@@ -12,12 +12,12 @@
 
 buildPythonPackage rec {
   pname = "zarr";
-  version = "2.9.1";
+  version = "2.9.4";
   disabled = isPy27;
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "688afec069e0f85b87c1ef4572766f998309c64ab7bea1884cec60e92d109544";
+    sha256 = "5544c47bc2a35f8e8af58bee92378518018b484ba550e997759d18f40fa75719";
   };
 
   nativeBuildInputs = [
diff --git a/pkgs/development/python-modules/zconfig/default.nix b/pkgs/development/python-modules/zconfig/default.nix
index a6a00ad821b8..521bca4ece8c 100644
--- a/pkgs/development/python-modules/zconfig/default.nix
+++ b/pkgs/development/python-modules/zconfig/default.nix
@@ -1,32 +1,27 @@
-{ lib, stdenv
+{ lib
+, stdenv
 , fetchPypi
-, fetchpatch
 , buildPythonPackage
 , zope_testrunner
 , manuel
 , docutils
-, pythonAtLeast
+, pygments
 }:
 
 buildPythonPackage rec {
   pname = "ZConfig";
-  version = "3.5.0";
+  version = "3.6.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "0s7aycxna07a04b4rswbkj4y5qh3gxy2mcsqb9dmy0iimj9f9550";
+    sha256 = "sha256-oo6VoK4zV5V0fsytNbLLcI831Ex/Ml4qyyAemDMLFuU=";
   };
 
-  patches = [
-    # fixes 3.8+ logger validation issues, has been merged into master, remove next bump
-    (fetchpatch {
-      url = "https://github.com/zopefoundation/ZConfig/commit/f0c2990d35ac3c924ecc8be4a5c71c8e4abbd0e5.patch";
-      sha256 = "1bjg3wrvii0rwzf3s0vlpzgg2ckj0h2zxkyxwjcr64s4k2vaq9ij";
-    })
-  ] ++ lib.optional stdenv.hostPlatform.isMusl ./remove-setlocale-test.patch;
+  patches = lib.optional stdenv.hostPlatform.isMusl ./remove-setlocale-test.patch;
 
   buildInputs = [ manuel docutils ];
   propagatedBuildInputs = [ zope_testrunner ];
+  checkInputs = [ pygments ];
 
   meta = with lib; {
     description = "Structured Configuration Library";
diff --git a/pkgs/development/python-modules/zigpy-xbee/default.nix b/pkgs/development/python-modules/zigpy-xbee/default.nix
index 1279bb804de6..be522214164b 100644
--- a/pkgs/development/python-modules/zigpy-xbee/default.nix
+++ b/pkgs/development/python-modules/zigpy-xbee/default.nix
@@ -7,11 +7,12 @@
 , pytest-asyncio
 , pytestCheckHook
 , pythonOlder
-, zigpy }:
+, zigpy
+}:
 
 buildPythonPackage rec {
   pname = "zigpy-xbee";
-  version = "0.13.0";
+  version = "0.14.0";
   # https://github.com/Martiusweb/asynctest/issues/152
   # broken by upstream python bug with asynctest and
   # is used exclusively by home-assistant with python 3.8
@@ -21,7 +22,7 @@ buildPythonPackage rec {
     owner = "zigpy";
     repo = "zigpy-xbee";
     rev = version;
-    sha256 = "Krdqb9bYKwUC2cdNppB2+tLwWjzmzIHhXnQ1KRduofU=";
+    sha256 = "sha256-veAkaBHPYgVd3iwvnH/A2upYX4T/qXXNRcaysbRQvNI=";
   };
 
   buildInputs = [
@@ -36,6 +37,12 @@ buildPythonPackage rec {
     pytestCheckHook
   ];
 
+  disabledTests = [
+    # assertion failure
+    # E       assert ff:ff:ff:ff:ff:ff:ff:ff is None
+    "test_startup_api_mode_config_fails"
+  ];
+
   meta = with lib; {
     description = "A library which communicates with XBee radios for zigpy";
     homepage = "https://github.com/zigpy/zigpy-xbee";
diff --git a/pkgs/development/python-modules/zigpy-znp/default.nix b/pkgs/development/python-modules/zigpy-znp/default.nix
index 474e7f309e34..f8413d9aa17f 100644
--- a/pkgs/development/python-modules/zigpy-znp/default.nix
+++ b/pkgs/development/python-modules/zigpy-znp/default.nix
@@ -18,13 +18,13 @@
 
 buildPythonPackage rec {
   pname = "zigpy-znp";
-  version = "0.5.3";
+  version = "0.5.4";
 
   src = fetchFromGitHub {
     owner = "zigpy";
     repo = pname;
     rev = "v${version}";
-    sha256 = "sha256-nnA/gVXBpCZFkspcO6kF3ZkEDu0vV0d9p1WNGVrN0u8=";
+    sha256 = "0jki9qmjazh0by02c0w17dyaz0nl3gzjiy064mj6pi502d175831";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/zigpy/default.nix b/pkgs/development/python-modules/zigpy/default.nix
index 7dab5cda6cc5..af498c59cf06 100644
--- a/pkgs/development/python-modules/zigpy/default.nix
+++ b/pkgs/development/python-modules/zigpy/default.nix
@@ -15,13 +15,13 @@
 
 buildPythonPackage rec {
   pname = "zigpy";
-  version = "0.36.1";
+  version = "0.37.1";
 
   src = fetchFromGitHub {
     owner = "zigpy";
     repo = "zigpy";
     rev = version;
-    sha256 = "0rfif8ds6m9ndxnc0f02fivc2pwidf476ylyx9y2b1sa2qz36z5w";
+    sha256 = "sha256-tDpu6tv8qwIPB3G5GKURtDi6QOYxF5jEVbzmJ2Px5W4=";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/zipp/default.nix b/pkgs/development/python-modules/zipp/default.nix
index 7ef26dbd7606..c070e2327772 100644
--- a/pkgs/development/python-modules/zipp/default.nix
+++ b/pkgs/development/python-modules/zipp/default.nix
@@ -2,31 +2,22 @@
 , buildPythonPackage
 , fetchPypi
 , setuptools-scm
-, pytest
-, pytest-flake8
 , more-itertools
-, toml
 }:
 
 buildPythonPackage rec {
   pname = "zipp";
-  version = "3.4.1";
+  version = "3.5.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "3607921face881ba3e026887d8150cca609d517579abe052ac81fc5aeffdbd76";
+    sha256 = "f5812b1e007e48cff63449a5e9f4e7ebea716b4111f9c4f9a645f91d579bf0c4";
   };
 
-  nativeBuildInputs = [ setuptools-scm toml ];
+  nativeBuildInputs = [ setuptools-scm ];
 
   propagatedBuildInputs = [ more-itertools ];
 
-  checkInputs = [ pytest pytest-flake8 ];
-
-  checkPhase = ''
-    pytest
-  '';
-
   # Prevent infinite recursion with pytest
   doCheck = false;
 
@@ -34,5 +25,6 @@ buildPythonPackage rec {
     description = "Pathlib-compatible object wrapper for zip files";
     homepage = "https://github.com/jaraco/zipp";
     license = licenses.mit;
+    maintainers = with maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/zodb/default.nix b/pkgs/development/python-modules/zodb/default.nix
index aa7cc6c97ebd..e4f1e403cd97 100644
--- a/pkgs/development/python-modules/zodb/default.nix
+++ b/pkgs/development/python-modules/zodb/default.nix
@@ -2,7 +2,6 @@
 , fetchPypi
 , buildPythonPackage
 , python
-, pythonAtLeast
 , zope_testrunner
 , transaction
 , six
@@ -16,46 +15,43 @@
 }:
 
 buildPythonPackage rec {
-    pname = "ZODB";
-    version = "5.6.0";
+  pname = "ZODB";
+  version = "5.6.0";
 
-    src = fetchPypi {
-      inherit pname version;
-      sha256 = "1zh7rd182l15swkbkm3ib0wgyn16xasdz2mzry8k4lwk6dagnm26";
-    };
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "1zh7rd182l15swkbkm3ib0wgyn16xasdz2mzry8k4lwk6dagnm26";
+  };
 
-    # remove broken test
-    postPatch = ''
-      rm -vf src/ZODB/tests/testdocumentation.py
-    '';
+  # remove broken test
+  postPatch = ''
+    rm -vf src/ZODB/tests/testdocumentation.py
+  '';
 
-    # ZConfig 3.5.0 is not compatible with Python 3.8
-    disabled = pythonAtLeast "3.8";
+  propagatedBuildInputs = [
+    transaction
+    six
+    zope_interface
+    zodbpickle
+    zconfig
+    persistent
+    zc_lockfile
+    BTrees
+  ];
 
-    propagatedBuildInputs = [
-      transaction
-      six
-      zope_interface
-      zodbpickle
-      zconfig
-      persistent
-      zc_lockfile
-      BTrees
-    ];
+  checkInputs = [
+    manuel
+    zope_testrunner
+  ];
 
-    checkInputs = [
-      manuel
-      zope_testrunner
-    ];
+  checkPhase = ''
+    ${python.interpreter} -m zope.testrunner --test-path=src []
+  '';
 
-    checkPhase = ''
-      ${python.interpreter} -m zope.testrunner --test-path=src []
-    '';
-
-    meta = with lib; {
-      description = "Zope Object Database: object database and persistence";
-      homepage = "https://pypi.python.org/pypi/ZODB";
-      license = licenses.zpl21;
-      maintainers = with maintainers; [ goibhniu ];
-    };
+  meta = with lib; {
+    description = "Zope Object Database: object database and persistence";
+    homepage = "https://pypi.python.org/pypi/ZODB";
+    license = licenses.zpl21;
+    maintainers = with maintainers; [ goibhniu ];
+  };
 }
diff --git a/pkgs/development/python-modules/zope_component/default.nix b/pkgs/development/python-modules/zope_component/default.nix
index 41c15fcd1307..a5cbcffe4336 100644
--- a/pkgs/development/python-modules/zope_component/default.nix
+++ b/pkgs/development/python-modules/zope_component/default.nix
@@ -12,11 +12,11 @@
 
 buildPythonPackage rec {
   pname = "zope.component";
-  version = "5.0.0";
+  version = "5.0.1";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "df541a0501c79123f9ac30c6686a9e45c2690c5c3ae4f2b7f4c6fd1a3aaaf614";
+    sha256 = "32cbe426ba8fa7b62ce5b211f80f0718a0c749cc7ff09e3f4b43a57f7ccdf5e5";
   };
 
   propagatedBuildInputs = [
diff --git a/pkgs/development/python-modules/zope_proxy/default.nix b/pkgs/development/python-modules/zope_proxy/default.nix
index 67e8a191d97a..2d1a5880d0de 100644
--- a/pkgs/development/python-modules/zope_proxy/default.nix
+++ b/pkgs/development/python-modules/zope_proxy/default.nix
@@ -6,11 +6,11 @@
 
 buildPythonPackage rec {
   pname = "zope.proxy";
-  version = "4.3.5";
+  version = "4.4.0";
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "a66a0d94e5b081d5d695e66d6667e91e74d79e273eee95c1747717ba9cb70792";
+    sha256 = "b244904c5148067c3f1899d29a2c1a28faca747b143192c0f825e6bf3170a347";
   };
 
   propagatedBuildInputs = [ zope_interface ];
diff --git a/pkgs/development/tools/rust/maturin/default.nix b/pkgs/development/tools/rust/maturin/default.nix
index 5ab47c8aa8de..9e7e39f3b721 100644
--- a/pkgs/development/tools/rust/maturin/default.nix
+++ b/pkgs/development/tools/rust/maturin/default.nix
@@ -11,16 +11,16 @@
 
 rustPlatform.buildRustPackage rec {
   pname = "maturin";
-  version = "0.10.6";
+  version = "0.11.3";
 
   src = fetchFromGitHub {
     owner = "PyO3";
     repo = "maturin";
     rev = "v${version}";
-    hash = "sha256-qWDrdS1zxe5woQSKLHhDSGJ1KF4SHk1mhaQApJXCCO4=";
+    hash = "sha256-jWkrjFQg0EqM+e/IT2n2E4lGL2kT/Wz7r5BLlzvWSO0=";
   };
 
-  cargoHash = "sha256-NEXgb7yWQkqbbofd3oYQ5n+CmfaM2cWj8HwufrcRKkc=";
+  cargoHash = "sha256-+kXwMGeE2HD59EU0Dzvg8I6LcHiPV7SKSFqnCTfkKwY=";
 
   nativeBuildInputs = [ pkg-config ];
 
diff --git a/pkgs/misc/pylode/default.nix b/pkgs/misc/pylode/default.nix
index 33e78bc15231..18e112346912 100644
--- a/pkgs/misc/pylode/default.nix
+++ b/pkgs/misc/pylode/default.nix
@@ -5,13 +5,13 @@
 
 python3Packages.buildPythonApplication rec {
   pname = "pyLODE";
-  version = "2.8.6";
+  version = "2.12.0";
 
   src = fetchFromGitHub {
     owner = "RDFLib";
     repo = pname;
     rev = version;
-    sha256 = "0zbk5lj9vlg32rmvw1himlw63kxd7sim7nzglrjs5zm6vpi4x5ch";
+    sha256 = "sha256-X/YiJduAJNiceIrlCFwD2PFiMn3HVlzr9NzyDvYcql8=";
   };
 
   propagatedBuildInputs = with python3Packages; [
@@ -22,7 +22,6 @@ python3Packages.buildPythonApplication rec {
     jinja2
     markdown
     rdflib
-    rdflib-jsonld
     requests
     six
     beautifulsoup4
diff --git a/pkgs/servers/calibre-web/default.nix b/pkgs/servers/calibre-web/default.nix
index ef322524ca92..b6dd0b987201 100644
--- a/pkgs/servers/calibre-web/default.nix
+++ b/pkgs/servers/calibre-web/default.nix
@@ -18,9 +18,9 @@ python3.pkgs.buildPythonApplication rec {
 
   prePatch = ''
     substituteInPlace setup.cfg \
-        --replace "requests>=2.11.1,<2.25.0" "requests>=2.11.1,<2.26.0" \
-        --replace "cps = calibreweb:main" "calibre-web = calibreweb:main" \
-        --replace "PyPDF3>=1.0.0,<1.0.4" "PyPDF3>=1.0.0"
+      --replace "requests>=2.11.1,<2.25.0" "requests" \
+      --replace "cps = calibreweb:main" "calibre-web = calibreweb:main" \
+      --replace "PyPDF3>=1.0.0,<1.0.4" "PyPDF3>=1.0.0"
   '';
 
   patches = [
diff --git a/pkgs/servers/home-assistant/default.nix b/pkgs/servers/home-assistant/default.nix
index 7bf04b65c723..3a9f7c7480d0 100644
--- a/pkgs/servers/home-assistant/default.nix
+++ b/pkgs/servers/home-assistant/default.nix
@@ -172,7 +172,9 @@ in with py.pkgs; buildPythonApplication rec {
       --replace "awesomeversion==21.4.0" "awesomeversion" \
       --replace "bcrypt==3.1.7" "bcrypt" \
       --replace "cryptography==3.3.2" "cryptography" \
+      --replace "httpx==0.18.2" "httpx>=0.18.2" \
       --replace "pip>=8.0.3,<20.3" "pip" \
+      --replace "requests==2.25.1" "requests>=2.25.1" \
       --replace "ruamel.yaml==0.15.100" "ruamel.yaml"
     substituteInPlace tests/test_config.py --replace '"/usr"' '"/build/media"'
   '';
diff --git a/pkgs/tools/admin/awscli/default.nix b/pkgs/tools/admin/awscli/default.nix
index 0d0d2ec80ffe..556539eddd2b 100644
--- a/pkgs/tools/admin/awscli/default.nix
+++ b/pkgs/tools/admin/awscli/default.nix
@@ -21,11 +21,11 @@ let
 in
 with py.pkgs; buildPythonApplication rec {
   pname = "awscli";
-  version = "1.19.97"; # N.B: if you change this, change botocore and boto3 to a matching version too
+  version = "1.19.106"; # N.B: if you change this, change botocore and boto3 to a matching version too
 
   src = fetchPypi {
     inherit pname version;
-    sha256 = "sha256-kecuyQMk4GWH9G0/f4Gi/hWtW4Zme9Q4i7XclcZTlNc=";
+    sha256 = "sha256-6o24GUcT3efgK5+Wa7n4+EeA5qXmAGhybzed7ybdT9Q=";
   };
 
   # https://github.com/aws/aws-cli/issues/4837
diff --git a/pkgs/tools/admin/azure-cli/python-packages.nix b/pkgs/tools/admin/azure-cli/python-packages.nix
index 2cde5a1da579..1cae7c1cc1fb 100644
--- a/pkgs/tools/admin/azure-cli/python-packages.nix
+++ b/pkgs/tools/admin/azure-cli/python-packages.nix
@@ -87,6 +87,7 @@ let
         postPatch = ''
           substituteInPlace setup.py \
             --replace "azure-mgmt-core>=1.2.0,<1.3.0" "azure-mgmt-core~=1.2" \
+            --replace "requests~=2.25.1" "requests~=2.25" \
             --replace "cryptography>=3.2,<3.4" "cryptography"
         '';
 
@@ -98,7 +99,7 @@ let
           PYTHONPATH=$PWD:$PYTHONPATH HOME=$TMPDIR pytest \
             --ignore=azure/cli/core/tests/test_profile.py \
             --ignore=azure/cli/core/tests/test_generic_update.py \
-            -k 'not metadata_url'
+            -k 'not metadata_url and not test_send_raw_requests'
         '';
 
         pythonImportsCheck = [
@@ -157,7 +158,7 @@ let
         "sha256-39msNYlZeZdn8cJ4LjZw9oxzy0YrNSPVEIN21wnkMKs=";
 
       azure-mgmt-recoveryservices = overrideAzureMgmtPackage super.azure-mgmt-recoveryservices "1.0.0" "zip"
-        "0v0ycyjnnx09jqf958hj2q6zfpsn80bxxm98jf59y8rj09v99rza";
+        "sha256-q4cQjA1c4n2AWDtL+tlmrQcEncvA6awoxkqmu9rmTiI=";
 
       azure-mgmt-recoveryservicesbackup = overrideAzureMgmtPackage super.azure-mgmt-recoveryservicesbackup "0.12.0" "zip"
         "sha256-mrw1Gs3LMOPFiL5mSSrm+g1/dxihplA6ItYHbwljJbM=";
@@ -201,6 +202,9 @@ let
       azure-mgmt-iothub = overrideAzureMgmtPackage super.azure-mgmt-iothub "2.0.0" "zip"
         "653a765f0beb6af0c9ecbd290b4101e1b5e0f6450405faf28ab8234c15d8b38b";
 
+      azure-mgmt-iothubprovisioningservices = overrideAzureMgmtPackage super.azure-mgmt-iothubprovisioningservices "0.2.0" "zip"
+        "sha256-jDes/Rwzq6hF8uAwLvcmbK0xy6UDzJkKSGhGWay3uR0=";
+
       azure-mgmt-iotcentral = overrideAzureMgmtPackage super.azure-mgmt-iotcentral "4.1.0" "zip"
         "e6d4810f454c0d63a5e816eaa7e54a073a3f70b2256162ff1c234cfe91783ae6";
 
diff --git a/pkgs/tools/security/wapiti/default.nix b/pkgs/tools/security/wapiti/default.nix
index cd89d4039e5f..38ba47a51223 100644
--- a/pkgs/tools/security/wapiti/default.nix
+++ b/pkgs/tools/security/wapiti/default.nix
@@ -104,6 +104,8 @@ python3.pkgs.buildPythonApplication rec {
     # Requires a PHP installation
     "test_timesql"
     "test_cookies"
+    # E           TypeError: Expected bytes or bytes-like object got: <class 'str'>
+    "test_persister_upload"
   ];
 
   pythonImportsCheck = [ "wapitiCore" ];
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 15f8a80e174b..7888af80493e 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -3598,7 +3598,7 @@ with pkgs;
 
   bud = callPackage ../tools/networking/bud { };
 
-  bump2version = python37Packages.callPackage ../applications/version-management/git-and-tools/bump2version { };
+  bump2version = python3Packages.callPackage ../applications/version-management/git-and-tools/bump2version { };
 
   bumpver = callPackage ../applications/version-management/bumpver { };
 
@@ -14739,9 +14739,7 @@ with pkgs;
 
   vultr-cli = callPackage ../development/tools/vultr-cli { };
 
-  vulnix = callPackage ../tools/security/vulnix {
-    python3Packages = python37Packages;
-  };
+  vulnix = callPackage ../tools/security/vulnix { };
 
   vtable-dumper = callPackage ../development/tools/misc/vtable-dumper { };
 
@@ -25272,11 +25270,7 @@ with pkgs;
 
   kubetail = callPackage ../applications/networking/cluster/kubetail { } ;
 
-  kupfer = callPackage ../applications/misc/kupfer {
-    # using python36 as there appears to be a waf issue with python37
-    # see https://github.com/NixOS/nixpkgs/issues/60498
-    python3Packages = python36Packages;
-  };
+  kupfer = callPackage ../applications/misc/kupfer { };
 
   kvirc = libsForQt514.callPackage ../applications/networking/irc/kvirc { };
 
diff --git a/pkgs/top-level/python-aliases.nix b/pkgs/top-level/python-aliases.nix
index cd35fb250390..27b467cbb2a4 100644
--- a/pkgs/top-level/python-aliases.nix
+++ b/pkgs/top-level/python-aliases.nix
@@ -33,7 +33,6 @@ in
   ### Deprecated aliases - for backward compatibility
 
 mapAliases ({
-  backports-entry-points-selectable = throw "backports-entry-points-selectable has been removed"; # added 2021-07-01
   blockdiagcontrib-cisco = throw "blockdiagcontrib-cisco is not compatible with blockdiag 2.0.0 and has been removed."; # Added 2020-11-29
   bt_proximity = bt-proximity; # added 2021-07-02
   bugseverywhere = throw "bugseverywhere has been removed: Abandoned by upstream."; # Added 2019-11-27
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index d581ad1fa00f..6e5a95ad7f63 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -565,6 +565,8 @@ in {
 
   asgiref = callPackage ../development/python-modules/asgiref { };
 
+  asn1 = callPackage ../development/python-modules/asn1 { };
+
   asn1ate = callPackage ../development/python-modules/asn1ate { };
 
   asn1crypto = callPackage ../development/python-modules/asn1crypto { };
@@ -623,9 +625,7 @@ in {
 
   async-timeout = callPackage ../development/python-modules/async_timeout { };
 
-  async-upnp-client = callPackage ../development/python-modules/async-upnp-client {
-    pytestCheckHook = self.pytestCheckHook_6_1;
-  };
+  async-upnp-client = callPackage ../development/python-modules/async-upnp-client { };
 
   asyncwhois = callPackage ../development/python-modules/asyncwhois { };
 
@@ -979,6 +979,8 @@ in {
 
   backports-datetime-fromisoformat = callPackage ../development/python-modules/backports-datetime-fromisoformat { };
 
+  backports-entry-points-selectable = callPackage ../development/python-modules/backports-entry-points-selectable { };
+
   backports_functools_lru_cache = callPackage ../development/python-modules/backports_functools_lru_cache { };
 
   backports_shutil_get_terminal_size = callPackage ../development/python-modules/backports_shutil_get_terminal_size { };
@@ -1856,6 +1858,8 @@ in {
 
   dateparser = callPackage ../development/python-modules/dateparser { };
 
+  dateutils = callPackage ../development/python-modules/dateutils { };
+
   datrie = callPackage ../development/python-modules/datrie { };
 
   dawg-python = callPackage ../development/python-modules/dawg-python { };
@@ -4254,8 +4258,9 @@ in {
   };
 
   llvmlite = callPackage ../development/python-modules/llvmlite {
-    llvm = pkgs.llvm_9;
-  }; # llvmlite always requires a specific version of llvm.
+    # llvmlite always requires a specific version of llvm.
+    llvm = pkgs.llvm_11;
+  };
 
   lmdb = callPackage ../development/python-modules/lmdb {
     inherit (pkgs) lmdb;
@@ -6866,6 +6871,11 @@ in {
       inherit version;
       sha256 = "c0a7e94a8cdbc5422a51ccdad8e6f1024795939cc89159a0ae7f0b316ad3823e";
     };
+
+    postPatch = ''
+      substituteInPlace setup.cfg \
+        --replace "pluggy>=0.12,<1.0" "pluggy>=0.12,<2.0"
+    '';
   });
 
   pytest-aiohttp = callPackage ../development/python-modules/pytest-aiohttp { };
@@ -8936,9 +8946,7 @@ in {
 
   trimesh = callPackage ../development/python-modules/trimesh { };
 
-  trio = callPackage ../development/python-modules/trio {
-    pytestCheckHook = self.pytestCheckHook_6_1;
-  };
+  trio = callPackage ../development/python-modules/trio { };
 
   trueskill = callPackage ../development/python-modules/trueskill { };
 
@@ -9156,9 +9164,7 @@ in {
 
   urlgrabber = callPackage ../development/python-modules/urlgrabber { };
 
-  urllib3 = callPackage ../development/python-modules/urllib3 {
-    pytestCheckHook = self.pytestCheckHook_6_1;
-  };
+  urllib3 = callPackage ../development/python-modules/urllib3 { };
 
   urlpy = callPackage ../development/python-modules/urlpy { };
 
@@ -9315,7 +9321,8 @@ in {
 
   wasm = callPackage ../development/python-modules/wasm { };
 
-  wasmer = callPackage ../development/python-modules/wasmer { };
+  wasmerPackages = pkgs.recurseIntoAttrs (callPackage ../development/python-modules/wasmer { });
+  inherit (self.wasmerPackages) wasmer wasmer-compiler-cranelift wasmer-compiler-llvm wasmer-compiler-singlepass;
 
   watchdog = callPackage ../development/python-modules/watchdog {
     inherit (pkgs.darwin.apple_sdk.frameworks) CoreServices;
@@ -9373,9 +9380,7 @@ in {
 
   webthing = callPackage ../development/python-modules/webthing { };
 
-  werkzeug = callPackage ../development/python-modules/werkzeug {
-    pytestCheckHook = self.pytestCheckHook_6_1;
-  };
+  werkzeug = callPackage ../development/python-modules/werkzeug { };
 
   west = callPackage ../development/python-modules/west { };
 
diff --git a/pkgs/top-level/python2-packages.nix b/pkgs/top-level/python2-packages.nix
index caa44e5947e1..57e6987e6703 100644
--- a/pkgs/top-level/python2-packages.nix
+++ b/pkgs/top-level/python2-packages.nix
@@ -70,6 +70,8 @@ with self; with super; {
 
   construct = callPackage ../development/python-modules/construct/2.10.54.nix { };
 
+  contextlib2 = callPackage ../development/python-modules/contextlib2/0.nix { };
+
   convertdate = callPackage ../development/python-modules/convertdate/2.2.x.nix { };
 
   cryptography = callPackage ../development/python-modules/cryptography/3.3.nix { };
@@ -80,6 +82,8 @@ with self; with super; {
 
   dateparser = callPackage ../development/python-modules/dateparser/0.x.nix { };
 
+  decorator = callPackage ../development/python-modules/decorator/4.nix { };
+
   deskcon = callPackage ../development/python-modules/deskcon { };
 
   django_evolution = callPackage ../development/python-modules/django_evolution { };
@@ -393,6 +397,8 @@ with self; with super; {
 
   pip = callPackage ../development/python-modules/pip/20.nix { };
 
+  pluggy = callPackage ../development/python-modules/pluggy/0.nix { };
+
   postorius = disabled super.postorius;
 
   praw = callPackage ../development/python-modules/praw/6.3.nix { };