diff --git a/pkgs/development/guile-modules/guile-lib/default.nix b/pkgs/development/guile-modules/guile-lib/default.nix
index 23576729ac02..75e45b00d4e7 100644
--- a/pkgs/development/guile-modules/guile-lib/default.nix
+++ b/pkgs/development/guile-modules/guile-lib/default.nix
@@ -1,6 +1,7 @@
 { lib
 , stdenv
 , fetchurl
+, autoreconfHook
 , guile
 , pkg-config
 , texinfo
@@ -16,6 +17,7 @@ stdenv.mkDerivation rec {
   };
 
   nativeBuildInputs = [
+    autoreconfHook
     pkg-config
   ];
   buildInputs = [
@@ -23,6 +25,12 @@ stdenv.mkDerivation rec {
     texinfo
   ];
 
+  postPatch = ''
+    substituteInPlace configure.ac \
+      --replace 'SITEDIR="$datadir/guile-lib"' 'SITEDIR=$datadir/guile/site/$GUILE_EFFECTIVE_VERSION' \
+      --replace 'SITECCACHEDIR="$libdir/guile-lib/guile/$GUILE_EFFECTIVE_VERSION/site-ccache"' 'SITECCACHEDIR="$libdir/guile/$GUILE_EFFECTIVE_VERSION/site-ccache"'
+  '';
+
   makeFlags = [ "GUILE_AUTO_COMPILE=0" ];
 
   doCheck = !stdenv.isDarwin;