diff --git a/pkgs/development/python-modules/beniget/default.nix b/pkgs/development/python-modules/beniget/default.nix
index 3e3e104a9062..b0dfc690841d 100644
--- a/pkgs/development/python-modules/beniget/default.nix
+++ b/pkgs/development/python-modules/beniget/default.nix
@@ -1,25 +1,36 @@
 {
   lib,
   buildPythonPackage,
-  fetchPypi,
+  fetchFromGitHub,
+  setuptools,
   gast,
+  pytestCheckHook,
 }:
 
 buildPythonPackage rec {
   pname = "beniget";
-  version = "0.4.1";
-  format = "setuptools";
+  version = "0.4.2.post1";
+  pyproject = true;
 
-  src = fetchPypi {
-    inherit pname version;
-    sha256 = "75554b3b8ad0553ce2f607627dad3d95c60c441189875b98e097528f8e23ac0c";
+  src = fetchFromGitHub {
+    owner = "serge-sans-paille";
+    repo = "beniget";
+    rev = "refs/tags/${version}";
+    hash = "sha256-rNMgCEkI6p9KtLSz/2jVJ9rPeJzxv5rT+Pu6OHM8z70=";
   };
 
-  propagatedBuildInputs = [ gast ];
+  build-system = [ setuptools ];
+
+  dependencies = [ gast ];
+
+  pythonImportsCheck = [ "beniget" ];
+
+  nativeCheckInputs = [ pytestCheckHook ];
 
   meta = {
     description = "Extract semantic information about static Python code";
     homepage = "https://github.com/serge-sans-paille/beniget";
     license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [ ];
   };
 }
diff --git a/pkgs/development/python-modules/gast/default.nix b/pkgs/development/python-modules/gast/default.nix
index e275cc3170c2..d62c2bc4cd41 100644
--- a/pkgs/development/python-modules/gast/default.nix
+++ b/pkgs/development/python-modules/gast/default.nix
@@ -5,22 +5,25 @@
   fetchFromGitHub,
   pytestCheckHook,
   pythonOlder,
+  setuptools,
 }:
 
 buildPythonPackage rec {
   pname = "gast";
-  version = "0.5.3";
-  format = "setuptools";
+  version = "0.6.0";
+  pyproject = true;
 
   disabled = pythonOlder "3.7";
 
   src = fetchFromGitHub {
     owner = "serge-sans-paille";
-    repo = pname;
-    rev = version;
-    hash = "sha256-0y2bHT7YEfTvDxTm6yLl3GmnPUYEieoGEnwkzfA6mOg=";
+    repo = "gast";
+    rev = "refs/tags/${version}";
+    hash = "sha256-zrbxW8qWhCY6tObP+/WDReoCnlCpMEzQucX2inpRTL4=";
   };
 
+  build-system = [ setuptools ];
+
   nativeCheckInputs = [
     astunparse
     pytestCheckHook
@@ -28,11 +31,11 @@ buildPythonPackage rec {
 
   pythonImportsCheck = [ "gast" ];
 
-  meta = with lib; {
+  meta = {
     description = "Compatibility layer between the AST of various Python versions";
     homepage = "https://github.com/serge-sans-paille/gast/";
-    license = licenses.bsd3;
-    maintainers = with maintainers; [
+    license = lib.licenses.bsd3;
+    maintainers = with lib.maintainers; [
       jyp
       cpcloud
     ];
diff --git a/pkgs/development/python-modules/pythran/default.nix b/pkgs/development/python-modules/pythran/default.nix
index e99283bc49ae..e74a9d62b210 100644
--- a/pkgs/development/python-modules/pythran/default.nix
+++ b/pkgs/development/python-modules/pythran/default.nix
@@ -3,7 +3,7 @@
   python,
   buildPythonPackage,
   fetchFromGitHub,
-  isPy3k,
+  fetchpatch2,
   substituteAll,
 
   # build-system
@@ -31,11 +31,16 @@ buildPythonPackage rec {
   src = fetchFromGitHub {
     owner = "serge-sans-paille";
     repo = "pythran";
-    rev = version;
+    rev = "refs/tags/${version}";
     hash = "sha256-TpD8YZnnv48PKYrUqR0/qvJG1XRbcMBcrkcERh6Q4q0=";
   };
 
   patches = [
+    (fetchpatch2 {
+      name = "bump-gast-to-0.6.0.patch";
+      url = "https://github.com/serge-sans-paille/pythran/commit/840a0e706ec39963aec6bcd1f118bf33177c20b4.patch";
+      hash = "sha256-FHGXWuAX/Nmn6uEfQgAXfUxIdApDwSfHHtOStxyme/0=";
+    })
     # Hardcode path to mp library
     (substituteAll {
       src = ./0001-hardcode-path-to-libgomp.patch;
@@ -51,9 +56,9 @@ buildPythonPackage rec {
     ln -s '${lib.getDev xsimd}'/include/xsimd pythran/
   '';
 
-  nativeBuildInputs = [ setuptools ];
+  build-system = [ setuptools ];
 
-  propagatedBuildInputs = [
+  dependencies = [
     ply
     gast
     numpy
@@ -73,9 +78,8 @@ buildPythonPackage rec {
   # Test suite is huge and has a circular dependency on scipy.
   doCheck = false;
 
-  disabled = !isPy3k;
-
   meta = {
+    changelog = "https://github.com/serge-sans-paille/pythran/blob/${src.rev}/Changelog";
     description = "Ahead of Time compiler for numeric kernels";
     homepage = "https://github.com/serge-sans-paille/pythran";
     license = lib.licenses.bsd3;