diff --git a/pkgs/desktops/gnome/core/mutter/42/fix-paths.patch b/pkgs/desktops/gnome/core/mutter/42/fix-paths.patch
deleted file mode 100644
index 6ac0a431f61f..000000000000
--- a/pkgs/desktops/gnome/core/mutter/42/fix-paths.patch
+++ /dev/null
@@ -1,13 +0,0 @@
-diff --git a/src/core/util.c b/src/core/util.c
-index 57b73747d..f424cc81c 100644
---- a/src/core/util.c
-+++ b/src/core/util.c
-@@ -636,7 +636,7 @@ meta_show_dialog (const char *type,
- 
-   args = g_ptr_array_new ();
- 
--  append_argument (args, "zenity");
-+  append_argument (args, "@zenity@/bin/zenity");
-   append_argument (args, type);
- 
-   if (display)
diff --git a/pkgs/desktops/gnome/core/mutter/42/default.nix b/pkgs/desktops/gnome/core/mutter/43/default.nix
similarity index 78%
rename from pkgs/desktops/gnome/core/mutter/42/default.nix
rename to pkgs/desktops/gnome/core/mutter/43/default.nix
index 3ee9f155df4f..f3d18b67c459 100644
--- a/pkgs/desktops/gnome/core/mutter/42/default.nix
+++ b/pkgs/desktops/gnome/core/mutter/43/default.nix
@@ -1,18 +1,18 @@
 { fetchurl
-, fetchpatch
-, substituteAll
 , runCommand
 , lib
+, fetchpatch
 , stdenv
 , pkg-config
 , gnome
 , gettext
 , gobject-introspection
 , cairo
+, colord
+, lcms2
 , pango
 , json-glib
 , libstartup_notification
-, zenity
 , libcanberra
 , ninja
 , xvfb-run
@@ -38,6 +38,7 @@
 , xorgserver
 , python3
 , wrapGAppsHook
+, gi-docgen
 , sysprof
 , libsysprof-capture
 , desktop-file-utils
@@ -47,15 +48,15 @@
 , wayland-protocols
 }:
 
-let self = stdenv.mkDerivation rec {
+stdenv.mkDerivation (finalAttrs: {
   pname = "mutter";
-  version = "42.7";
+  version = "43.4";
 
-  outputs = [ "out" "dev" "man" ];
+  outputs = [ "out" "dev" "man" "devdoc" ];
 
   src = fetchurl {
-    url = "mirror://gnome/sources/mutter/${lib.versions.major version}/${pname}-${version}.tar.xz";
-    sha256 = "OwmmsHDRMHwD2EMorIS0+m1jmfk4MEo4wpTxso3yipM=";
+    url = "mirror://gnome/sources/mutter/${lib.versions.major finalAttrs.version}/mutter-${finalAttrs.version}.tar.xz";
+    sha256 = "FiU2cxEaLsyW/I0tFfrdobVU0B3CioMEE11J1rqHsUA=";
   };
 
   patches = [
@@ -65,11 +66,6 @@ let self = stdenv.mkDerivation rec {
       url = "https://gitlab.gnome.org/GNOME/mutter/-/commit/285a5a4d54ca83b136b787ce5ebf1d774f9499d5.patch";
       sha256 = "/npUE3idMSTVlFptsDpZmGWjZ/d2gqruVlJKq4eF4xU=";
     })
-
-    (substituteAll {
-      src = ./fix-paths.patch;
-      inherit zenity;
-    })
   ];
 
   mesonFlags = [
@@ -81,6 +77,7 @@ let self = stdenv.mkDerivation rec {
     # This should be auto detected, but it looks like it manages a false
     # positive.
     "-Dxwayland_initfd=disabled"
+    "-Ddocs=true"
   ];
 
   propagatedBuildInputs = [
@@ -102,6 +99,7 @@ let self = stdenv.mkDerivation rec {
     pkg-config
     python3
     wrapGAppsHook
+    gi-docgen
     xorgserver
   ];
 
@@ -123,6 +121,8 @@ let self = stdenv.mkDerivation rec {
     libxkbcommon
     libxkbfile
     libXdamage
+    colord
+    lcms2
     pango
     pipewire
     sysprof # for D-Bus interfaces
@@ -140,16 +140,24 @@ let self = stdenv.mkDerivation rec {
     ${glib.dev}/bin/glib-compile-schemas "$out/share/glib-2.0/schemas"
   '';
 
+  postFixup = ''
+    # Cannot be in postInstall, otherwise _multioutDocs hook in preFixup will move right back.
+    # TODO: Move this into a directory devhelp can find.
+    moveToOutput "share/mutter-11/doc" "$devdoc"
+  '';
+
   # Install udev files into our own tree.
   PKG_CONFIG_UDEV_UDEVDIR = "${placeholder "out"}/lib/udev";
 
+  separateDebugInfo = true;
+
   passthru = {
-    libdir = "${self}/lib/mutter-10";
+    libdir = "${finalAttrs.finalPackage}/lib/mutter-11";
 
     tests = {
       libdirExists = runCommand "mutter-libdir-exists" {} ''
-        if [[ ! -d ${self.libdir} ]]; then
-          echo "passthru.libdir should contain a directory, “${self.libdir}” is not one."
+        if [[ ! -d ${finalAttrs.finalPackage.libdir} ]]; then
+          echo "passthru.libdir should contain a directory, “${finalAttrs.finalPackage.libdir}” is not one."
           exit 1
         fi
         touch $out
@@ -164,5 +172,4 @@ let self = stdenv.mkDerivation rec {
     maintainers = teams.pantheon.members;
     platforms = platforms.linux;
   };
-};
-in self
+})
diff --git a/pkgs/desktops/gnome/default.nix b/pkgs/desktops/gnome/default.nix
index 155d8413ee2a..cfd47ddda45c 100644
--- a/pkgs/desktops/gnome/default.nix
+++ b/pkgs/desktops/gnome/default.nix
@@ -97,7 +97,7 @@ lib.makeScope pkgs.newScope (self: with self; {
   mutter = callPackage ./core/mutter { };
 
   # Needed for elementary's gala, wingpanel and greeter until support for higher versions is provided
-  mutter42 = callPackage ./core/mutter/42 { };
+  mutter43 = callPackage ./core/mutter/43 { };
 
   nautilus = callPackage ./core/nautilus { };
 
@@ -272,5 +272,6 @@ lib.makeScope pkgs.newScope (self: with self; {
   gnome-devel-docs = throw "The ‘gnome.gnome-devel-docs’ package was removed as it is outdated and no longer relevant."; # added 2022-10-26
 
   mutter338 = throw "The ‘gnome.mutter338’ package was removed as it is no longer needed by Pantheon."; # added 2023-02-22
+  mutter42 = throw "The ‘gnome.mutter42’ package was removed as it is no longer needed by Pantheon."; # added 2023-03-23
   gnome-settings-daemon338 = throw "The ‘gnome.gnome-settings-daemon338’ package was removed as it is no longer needed by Pantheon."; # added 2023-02-22
 }
diff --git a/pkgs/desktops/pantheon/default.nix b/pkgs/desktops/pantheon/default.nix
index a96cce755c97..b5ce60985bd7 100644
--- a/pkgs/desktops/pantheon/default.nix
+++ b/pkgs/desktops/pantheon/default.nix
@@ -40,7 +40,7 @@ lib.makeScope pkgs.newScope (self: with self; {
 
   maintainers = lib.teams.pantheon.members;
 
-  mutter = pkgs.gnome.mutter42;
+  mutter = pkgs.gnome.mutter43;
 
   # Using 42 to match Mutter used in Pantheon
   gnome-settings-daemon = pkgs.gnome.gnome-settings-daemon42;