diff --git a/pkgs/applications/science/biology/bwa/default.nix b/pkgs/applications/science/biology/bwa/default.nix
index d9ae226027a0..aeea7ed26465 100644
--- a/pkgs/applications/science/biology/bwa/default.nix
+++ b/pkgs/applications/science/biology/bwa/default.nix
@@ -1,24 +1,16 @@
-{ lib, stdenv, fetchurl, fetchpatch, zlib }:
+{ lib, stdenv, fetchFromGitHub, zlib }:
 
-stdenv.mkDerivation rec {
+stdenv.mkDerivation {
   pname = "bwa";
-  version = "0.7.17";
+  version = "unstable-2022-09-23";
 
-  src = fetchurl {
-    url = "mirror://sourceforge/bio-bwa/${pname}-${version}.tar.bz2";
-    sha256 = "1zfhv2zg9v1icdlq4p9ssc8k01mca5d1bd87w71py2swfi74s6yy";
+  src = fetchFromGitHub {
+    owner = "lh3";
+    repo = "bwa";
+    rev = "139f68fc4c3747813783a488aef2adc86626b01b";
+    hash = "sha256-8u35lTK6gBKeapYoIkG9MuJ/pyy/HFA2OiPn+Ml2C6c=";
   };
 
-  patches = [
-    # Pull upstream patch for -fno-common toolchain support like upstream
-    # gcc-10: https://github.com/lh3/bwa/pull/267
-    (fetchpatch {
-      name  = "fno-common.patch";
-      url = "https://github.com/lh3/bwa/commit/2a1ae7b6f34a96ea25be007ac9d91e57e9d32284.patch";
-      sha256 = "1lihfxai6vcshv5vr3m7yhk833bdivkja3gld6ilwrc4z28f6wqy";
-    })
-  ];
-
   buildInputs = [ zlib ];
 
   # Avoid hardcoding gcc to allow environments with a different
@@ -45,6 +37,6 @@ stdenv.mkDerivation rec {
     license     = licenses.gpl3;
     homepage    = "https://bio-bwa.sourceforge.net/";
     maintainers = with maintainers; [ luispedro ];
-    platforms = platforms.x86_64;
+    platforms = platforms.unix;
   };
 }